Direct factor Xa inhibitors
- Name
- Direct factor Xa inhibitors
- Accession Number
- DBCAT005262
- Description
Not Available
- ATC Classification
- Drugs
Drug Drug Description Rivaroxaban A factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations. Dabigatran Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate. Apixaban An anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery. Edoxaban A novel oral anticoagulant used for reducing the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF). Betrixaban A Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients. - Drugs & Drug Targets
Drug Target Type Rivaroxaban Coagulation factor X target Rivaroxaban Cytochrome P450 3A4 enzyme Rivaroxaban Cytochrome P450 2J2 enzyme Rivaroxaban P-glycoprotein 1 transporter Rivaroxaban Cytochrome P450 3A5 enzyme Rivaroxaban ATP-binding cassette sub-family G member 2 transporter Apixaban Coagulation factor X target Apixaban Cytochrome P450 3A4 enzyme Apixaban Cytochrome P450 1A2 enzyme Apixaban Cytochrome P450 2C8 enzyme Apixaban Cytochrome P450 2C9 enzyme Apixaban Cytochrome P450 2C19 enzyme Apixaban Cytochrome P450 2J2 enzyme Apixaban P-glycoprotein 1 transporter Apixaban ATP-binding cassette sub-family G member 2 transporter Apixaban Cytochrome P450 3A5 enzyme Edoxaban Coagulation factor X target Edoxaban P-glycoprotein 1 transporter Betrixaban P-glycoprotein 1 transporter Betrixaban Coagulation factor X target Betrixaban Potassium voltage-gated channel subfamily H member 2 transporter