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Identification
NameHydroxyzine
Accession NumberDB00557  (APRD00688)
TypeSmall Molecule
GroupsApproved
DescriptionA histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite cetirizine, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative. [PubChem]
Structure
Thumb
Synonyms
Hidroxizina
Hychotine
Hydroksyzyny
Hydroxine
Hydroxizine
Hydroxizinum
Hydroxycine
Hydroxyzin
Hydroxyzine
Hydroxyzinum
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Atarax Cap 10mgcapsule10 mgoralErfa Canada 2012 Inc1956-12-312005-09-15Canada
Atarax Cap 25mgcapsule25 mgoralErfa Canada 2012 Inc1956-12-312005-09-15Canada
Atarax Cap 50mgcapsule50 mgoralErfa Canada 2012 Inc1959-12-312005-09-15Canada
Atarax Im Sol 50mg/mlsolution50 mgintramuscularErfa Canada 2012 Inc1957-12-312005-08-18Canada
Atarax Syrup 2mg/mlsyrup2 mgoralErfa Canada 2012 Inc1956-12-31Not applicableCanada
Hydroxyzine Hydrochloride Injectionliquid50 mgintramuscularFresenius Kabi Canada Ltd2001-04-05Not applicableCanada
Hydroxyzine Hydrochloride Injection USPliquid50 mgintramuscularSandoz Canada Incorporated1987-12-31Not applicableCanada
Hydroxyzine Hydrochloride Injection, USPsolution50 mgintramuscularSterimax Inc1997-05-16Not applicableCanada
Hydroxyzine-10capsule10 mgoralPro Doc Limitee1987-12-312014-07-24Canada
Hydroxyzine-25capsule25 mgoralPro Doc Limitee1987-12-312014-07-24Canada
Hydroxyzine-50capsule50 mgoralPro Doc Limitee1987-12-312014-07-24Canada
Multipax Cap 10mgcapsule10 mgoralRhone Poulenc Rorer Canada Inc.1992-12-311997-08-13Canada
Multipax Cap 25mgcapsule25 mgoralRhone Poulenc Rorer Canada Inc.1992-12-312000-07-28Canada
Novo-hydroxyzincapsule50 mgoralTeva Canada Limited1987-12-31Not applicableCanada
Novo-hydroxyzincapsule10 mgoralTeva Canada Limited1987-12-31Not applicableCanada
Novo-hydroxyzincapsule25 mgoralTeva Canada Limited1987-12-31Not applicableCanada
Nu-hydroxyzinecapsule50 mgoralNu Pharm Inc1995-12-312012-09-04Canada
Nu-hydroxyzinecapsule25 mgoralNu Pharm Inc1995-12-312012-09-04Canada
Nu-hydroxyzinecapsule10 mgoralNu Pharm Inc1995-12-312012-09-04Canada
PMS Hydroxyzine Cap 10mgcapsule10 mgoralPharmascience Inc1988-12-31Not applicableCanada
PMS Hydroxyzine Cap 25mgcapsule25 mgoralPharmascience Inc1988-12-31Not applicableCanada
PMS Hydroxyzine Cap 50mgcapsule50 mgoralPharmascience Inc1988-12-31Not applicableCanada
PMS Hydroxyzine Syr 10mg/5mlsyrup10 mgoralPharmascience Inc1988-12-31Not applicableCanada
Riva-hydroxyzin 10mg Capsulescapsule10 mgoralLaboratoire Riva Inc1999-11-232013-07-31Canada
Riva-hydroxyzin 25mg Capsulescapsule25 mgoralLaboratoire Riva Inc1999-11-232013-07-31Canada
Riva-hydroxyzin 50mg Capsulescapsule50 mgoralLaboratoire Riva Inc1999-11-232013-07-31Canada
Vistarilsolution50 mg/mLintramuscularRoerig1957-09-18Not applicableUs
Vistarilcapsule25 mg/1oralPfizer Laboratories Div Pfizer Inc1994-11-28Not applicableUs
Vistarilcapsule50 mg/1oralPfizer Laboratories Div Pfizer Inc1968-11-15Not applicableUs
Vistarilcapsule50 mg/1oralREMEDYREPACK INC.2013-03-11Not applicableUs
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo Hydroxyzine Cap 10mgcapsule10 mgoralApotex Inc1986-12-31Not applicableCanada
Apo Hydroxyzine Cap 25mgcapsule25 mgoralApotex Inc1986-12-31Not applicableCanada
Apo Hydroxyzine Cap 50mgcapsule50 mgoralApotex Inc1986-12-31Not applicableCanada
Hydoxyzine Pamoatecapsule25 mg/1oralPd Rx Pharmaceuticals, Inc.1981-12-14Not applicableUs
Hydroxyzinetablet, film coated50 mg/1oralMajor Pharmaceuticals2007-03-20Not applicableUs
Hydroxyzineinjection, solution50 mg/mLintramuscularGeneral Injectables & Vaccines, Inc2010-03-01Not applicableUs
Hydroxyzinetablet, film coated10 mg/1oralBlenheim Pharmacal, Inc.2009-12-28Not applicableUs
Hydroxyzineinjection, solution50 mg/mLintramuscularGeneral Injectables & Vaccines, Inc2010-03-01Not applicableUs
Hydroxyzinetablet, film coated10 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2007-03-20Not applicableUs
Hydroxyzinetablet, film coated25 mg/1oralBlenheim Pharmacal, Inc.2010-05-17Not applicableUs
Hydroxyzinetablet, film coated10 mg/1oralMajor Pharmaceuticals2007-03-20Not applicableUs
Hydroxyzinesolution10 mg/5mLoralPreferred Pharmaceuticals, Inc.2015-08-21Not applicableUs
Hydroxyzineinjection, solution50 mg/mLintramuscularGeneral Injectables & Vaccines, Inc2010-03-01Not applicableUs
Hydroxyzinetablet, film coated25 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2007-03-20Not applicableUs
Hydroxyzinetablet, film coated25 mg/1oralMajor Pharmaceuticals2007-03-20Not applicableUs
Hydroxyzineinjection, solution25 mg/mLintramuscularGeneral Injectables & Vaccines, Inc2010-03-01Not applicableUs
Hydroxyzinetablet, film coated50 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2007-03-20Not applicableUs
Hydroxyzine HClsolution10 mg/5mLoralSTI Pharma LLC1982-01-01Not applicableUs
Hydroxyzine HCltablet, film coated10 mg/1oralDIRECT RX2016-02-12Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralLake Erie Medical DBA Quality Care Products LLC2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralPd Rx Pharmaceuticals, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralProficient Rx LP2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralWatson Laboratories, Inc.2011-11-212016-02-11Us
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralRebel Distributors Corp2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralAmerican Health Packaging2009-01-13Not applicableUs
Hydroxyzine Hydrochloridesolution10 mg/5mLoralSilarx Pharmaceuticals, Inc.2013-08-21Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralA S Medication Solutions Llc2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralA S Medication Solutions Llc2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet10 mg/1oralCaraco Pharmaceutical Laboratories, Ltd.2009-03-31Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralEpic Pharma, LLC2015-03-31Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution50 mg/mLintramuscularAmerican Regent, Inc.1990-09-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralTeva Pharmaceuticals USA Inc2013-02-19Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralGlenmark Generics Inc., USA2008-03-01Not applicableUs
Hydroxyzine Hydrochloridetablet25 mg/1oralREMEDYREPACK INC.2011-05-16Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralNorthwind Pharmaceuticals, LLC2015-02-26Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralDispensing Solutions, Inc.2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralGlenmark Pharmaceuticals Inc., Usa2015-02-01Not applicableUs
Hydroxyzine Hydrochloridetablet10 mg/1oralHeritage Pharmaceuticals Inc.2012-03-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralMylan Institutional Inc.2010-08-13Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralAidarex Pharmaceuticals LLC2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralPhysicians Total Care, Inc.1994-04-04Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralPd Rx Pharmaceuticals, Inc.2010-12-07Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralProficient Rx LP2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralQualitest Pharmaceuticals2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralMylan Pharmaceuticals Inc.2010-07-23Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralHeritage Pharmaceuticals Inc.2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralHarris Pharmaceutical, Inc.2007-06-29Not applicableUs
Hydroxyzine Hydrochloridetablet25 mg/1oralNorthstar Rx LLC2009-11-11Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralREMEDYREPACK INC.2014-03-03Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralClinical Solutions Wholesale2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralKAISER FOUNDATION HOSPITALS2010-10-08Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralA S Medication Solutions Llc2005-05-27Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution50 mg/mLintramuscularCardinal Health1990-09-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralLake Erie Medical DBA Quality Care Products LLC2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralGolden State Medical Supply, Inc.2008-09-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralPd Rx Pharmaceuticals, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralProficient Rx LP2007-06-29Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralWatson Laboratories, Inc.2011-11-212016-02-11Us
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralBlenheim Pharmacal, Inc.2010-09-15Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralRebel Distributors Corp2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralAmerican Health Packaging2009-01-13Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralPreferred Pharmaceuticals, Inc.2012-10-08Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralKvk Tech, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralA S Medication Solutions Llc2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralREMEDYREPACK INC.2013-06-04Not applicableUs
Hydroxyzine Hydrochloridesyrup10 mg/5mLoralPhysicians Total Care, Inc.2000-09-13Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralCamber Pharmaceuticals, Inc.2008-05-29Not applicableUs
Hydroxyzine Hydrochloridetablet25 mg/1oralCaraco Pharmaceutical Laboratories, Ltd.2009-03-31Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralPd Rx Pharmaceuticals, Inc.2007-06-29Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution50 mg/mLintramuscularAmerican Regent, Inc.1990-09-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralTeva Pharmaceuticals USA Inc2012-10-09Not applicableUs
Hydroxyzine Hydrochloridesolution10 mg/5mLoralKvk Tech, Inc.2008-09-26Not applicableUs
Hydroxyzine Hydrochloridetablet10 mg/1oralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2011-03-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralRed Pharm Drug Inc.2009-08-07Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution25 mg/mLintramuscularFresenius Kabi USA, LLC2000-10-17Not applicableUs
Hydroxyzine Hydrochloridetablet25 mg/1oralREMEDYREPACK INC.2011-03-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralHeritage Pharmaceuticals Inc.2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralGlenmark Pharmaceuticals Inc., Usa2015-02-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralLife Line Home Care Services, Inc.2012-01-18Not applicableUs
Hydroxyzine Hydrochloridetablet25 mg/1oralHeritage Pharmaceuticals Inc.2012-03-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralMylan Institutional Inc.2010-08-13Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralPhysicians Total Care, Inc.1994-07-28Not applicableUs
Hydroxyzine Hydrochloridecapsule50 mg/1oralREMEDYREPACK INC.2011-08-12Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralQualitest Pharmaceuticals2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralLiberty Pharmaceuticals, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralKAISER FOUNDATION HOSPITALS2010-10-08Not applicableUs
Hydroxyzine Hydrochloridetablet50 mg/1oralNorthstar Rx LLC2009-11-11Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralHarris Pharmaceutical, Inc.2007-06-29Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralREMEDYREPACK INC.2016-02-11Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralA S Medication Solutions Llc2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralPd Rx Pharmaceuticals, Inc.2007-06-29Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralH.J. Harkins Company, Inc.2008-06-30Not applicableUs
Hydroxyzine Hydrochloridesyrup10 mg/5mLoralA S Medication Solutions Llc1995-03-09Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution25 mg/mLintramuscularCardinal Health1990-09-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralGolden State Medical Supply, Inc.2012-08-22Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralPd Rx Pharmaceuticals, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochloridesyrup10 mg/5mLoralProficient Rx LP1995-03-09Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralWatson Laboratories, Inc.2011-11-212016-02-11Us
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralMylan Pharmaceuticals Inc.2010-07-23Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralBlenheim Pharmacal, Inc.2011-04-18Not applicableUs
Hydroxyzine Hydrochloridesolution10 mg/5mLoralPreferred Pharmaceuticals, Inc.2015-01-13Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralKvk Tech, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution50 mg/mLintramuscularFresenius Kabi USA, LLC2000-08-08Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-21Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralREMEDYREPACK INC.2013-05-282016-04-05Us
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralState of Florida DOH Central Pharmacy2013-01-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralCamber Pharmaceuticals, Inc.2008-05-29Not applicableUs
Hydroxyzine Hydrochloridetablet50 mg/1oralCaraco Pharmaceutical Laboratories, Ltd.2009-03-31Not applicableUs
Hydroxyzine Hydrochloridetablet50 mg/1oralREMEDYREPACK INC.2015-12-14Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralTeva Pharmaceuticals USA Inc2012-10-22Not applicableUs
Hydroxyzine Hydrochloridetablet25 mg/1oralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2011-03-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralRed Pharm Drug Inc.2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralQualitest Pharmaceuticals2005-05-27Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution25 mg/mLintramuscularAmerican Regent, Inc.1990-09-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralBlenheim Pharmacal, Inc.2013-11-18Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralGlenmark Generics Inc., USA2008-03-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralMc Kesson Contract Packaging2012-01-23Not applicableUs
Hydroxyzine Hydrochloridetablet50 mg/1oralHeritage Pharmaceuticals Inc.2012-03-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralMylan Institutional Inc.2010-08-13Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralPhysicians Total Care, Inc.1993-09-21Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralEpic Pharma, LLC2015-03-31Not applicableUs
Hydroxyzine Hydrochloridesyrup10 mg/5mLoralMorton Grove Pharmaceuticals, Inc.1995-03-09Not applicableUs
Hydroxyzine Hydrochloridetablet50 mg/1oralREMEDYREPACK INC.2011-03-11Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralbryant ranch prepack2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralRebel Distributors Corp2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralAmerican Health Packaging2009-01-13Not applicableUs
Hydroxyzine Hydrochloridesolution10 mg/5mLoralPreferred Pharmaceuticals, Inc.2014-02-06Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralA S Medication Solutions Llc2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralA S Medication Solutions Llc2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralCardinal Health2010-07-23Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralPd Rx Pharmaceuticals, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralKvk Tech, Inc.2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralPd Rx Pharmaceuticals, Inc.2005-05-27Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralGolden State Medical Supply, Inc.2008-09-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralProficient Rx LP2008-06-30Not applicableUs
Hydroxyzine Hydrochloridesolution10 mg/5mLoralQualitest Pharmaceuticals2002-04-10Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralMylan Pharmaceuticals Inc.2010-07-23Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralBlenheim Pharmacal, Inc.2012-11-16Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralHeritage Pharmaceuticals Inc.2008-06-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralGlenmark Pharmaceuticals Inc., Usa2015-02-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralHarris Pharmaceutical, Inc.2007-06-29Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralPreferred Pharmaceuticals, Inc.2015-04-15Not applicableUs
Hydroxyzine Hydrochloridetablet10 mg/1oralNorthstar Rx LLC2009-11-11Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-28Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralREMEDYREPACK INC.2014-01-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralState of Florida DOH Central Pharmacy2013-01-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralCardinal Health2009-01-13Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralCamber Pharmaceuticals, Inc.2008-05-29Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralClinical Solutions Wholesale2012-07-24Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralDIRECT RX2015-01-01Not applicableUs
Hydroxyzine Hydrochloridesyrup10 mg/5mLoralPharmaceutical Associates, Inc.2015-01-01Not applicableUs
Hydroxyzine Hydrochlorideinjection, solution50 mg/mLintramuscularAmerican Regent, Inc.1990-09-30Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralBlenheim Pharmacal, Inc.2013-11-18Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralRed Pharm Drug Inc.2010-12-07Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralGlenmark Generics Inc., USA2008-03-01Not applicableUs
Hydroxyzine Hydrochloridesolution10 mg/5mLoralHi Tech Pharmacal Co., Inc.1994-10-28Not applicableUs
Hydroxyzine Hydrochloridetablet10 mg/1oralNorthwind Pharmaceuticals, LLC2014-09-15Not applicableUs
Hydroxyzine Hydrochloridesolution10 mg/5mLoralPhysicians Total Care, Inc.1994-08-01Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated10 mg/1oralPd Rx Pharmaceuticals, Inc.2007-06-29Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated25 mg/1oralEpic Pharma, LLC2015-03-31Not applicableUs
Hydroxyzine Hydrochloridetablet25 mg/1oralREMEDYREPACK INC.2011-05-23Not applicableUs
Hydroxyzine Hydrochloridetablet, film coated50 mg/1oralbryant ranch prepack2008-06-30Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralClinical Solutions Wholsesale1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralEon Labs, Inc.1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralTYA Pharmaceuticals1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralPreferred Pharmaceuticals, Inc.2013-04-22Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralCardinal Health2012-09-25Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralPhysicians Total Care, Inc.2000-02-09Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralREMEDYREPACK INC.2013-06-24Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralREMEDYREPACK INC.2015-03-09Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralBlenheim Pharmacal, Inc.2013-11-11Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralbryant ranch prepack1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralRed Pharm Drug Inc.2010-07-01Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralA S Medication Solutions1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralAvera Mc Kennan Hospital2015-03-01Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralWestwood Manufacturing2010-11-17Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralGolden State Medical Supply, Inc.2014-05-20Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralREMEDYREPACK INC.2011-08-03Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralSTAT Rx USA LLC1996-06-15Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralTYA Pharmaceuticals2010-11-17Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralPreferred Pharmaceuticals, Inc.2014-07-23Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralCardinal Health2013-06-12Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralAidarex Pharmaceuticals LLC1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralPd Rx Pharmaceuticals, Inc.1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralDIRECT RX2014-01-01Not applicableUs
Hydroxyzine Pamoatecapsule100 mg/1oralBarr Laboratories Inc.1984-07-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-06-27Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralEon Labs, Inc.2014-06-27Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralTYA Pharmaceuticals1996-06-15Not applicableUs
Hydroxyzine Pamoatecapsule100 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralREMEDYREPACK INC.2015-10-20Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralPreferred Pharmaceuticals, Inc.2004-07-21Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralContract Pharmacy Services Pa2010-08-16Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralPd Rx Pharmaceuticals, Inc.1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralSTAT Rx USA LLC1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralGolden State Medical Supply, Inc.2014-05-20Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralbryant ranch prepack1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralTYA Pharmaceuticals1984-07-01Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralCardinal Health2011-08-03Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralClinical Solutions Wholsesale1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralAmerican Health Packaging2013-06-12Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralWatson Laboratories, Inc.1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralMylan Institutional Inc.2007-11-26Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralAv Kare, Inc.2013-03-07Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralRebel Distributors Corp1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralRising Pharmaceuticals Inc.2010-11-17Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralAmerican Health Packaging2015-02-15Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralBarr Laboratories Inc.1984-07-01Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralApotheca Inc.1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralPreferred Pharmaceuticals, Inc.2004-07-21Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralREMEDYREPACK INC.2013-03-19Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralContract Pharmacy Services Pa2010-08-16Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralPd Rx Pharmaceuticals, Inc.1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralWatson Laboratories, Inc.1996-06-15Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralEon Labs, Inc.1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralTYA Pharmaceuticals1984-07-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralLake Erie Medical DBA Quality Care Products LLC1984-07-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralClinical Solutions Wholsesale1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralProficient Rx LP1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralAvera Mc Kennan Hospital2015-03-04Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralMylan Institutional Inc.2007-11-26Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralH.J. Harkins Company, Inc.2010-07-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralA S Medication Solutions Llc1981-12-142016-04-05Us
Hydroxyzine Pamoatecapsule50 mg/1oralAv Kare, Inc.2013-03-07Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralAphena Pharma Solutions Tennessee, Llc1996-07-15Not applicableUs
Hydroxyzine Pamoatecapsule50 mg/1oralRising Pharmaceuticals Inc.2010-11-17Not applicableUs
Hydroxyzine Pamoatecapsule100 mg/1oralPd Rx Pharmaceuticals, Inc.2011-09-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralBarr Laboratories Inc.1984-07-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralSTAT Rx USA LLC1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralTYA Pharmaceuticals2010-11-17Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs1981-12-14Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralREMEDYREPACK INC.2013-04-08Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralAmerican Health Packaging2013-06-122015-11-30Us
Hydroxyzine Pamoatecapsule25 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Hydroxyzine Pamoatecapsule25 mg/1oralREMEDYREPACK INC.2015-03-09Not applicableUs
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International Brands
NameCompany
AtaraxUCB
HyzineHyrex
MasmoranPfizer
RezineNot Available
Vistaject-50Not Available
VistazineNot Available
Brand mixturesNot Available
Salts
Name/CASStructureProperties
Hydroxyzine hydrochloride
2192-20-3
Thumb
  • InChI Key: ANOMHKZSQFYSBR-UHFFFAOYNA-N
  • Monoisotopic Mass: 446.129461303
  • Average Mass: 447.826
DBSALT000343
Hydroxyzine pamoate
ThumbNot applicableDBSALT000984
Categories
UNII30S50YM8OG
CAS number68-88-2
WeightAverage: 374.904
Monoisotopic: 374.176105825
Chemical FormulaC21H27ClN2O2
InChI KeyInChIKey=ZQDWXGKKHFNSQK-UHFFFAOYSA-N
InChI
InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2
IUPAC Name
2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethan-1-ol
SMILES
OCCOCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=C(Cl)C=C1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassDiphenylmethanes
Direct ParentDiphenylmethanes
Alternative Parents
Substituents
  • Diphenylmethane
  • Aralkylamine
  • N-alkylpiperazine
  • Halobenzene
  • Chlorobenzene
  • Piperazine
  • 1,4-diazinane
  • Aryl halide
  • Aryl chloride
  • Tertiary aliphatic amine
  • Tertiary amine
  • Azacycle
  • Organoheterocyclic compound
  • Ether
  • Dialkyl ether
  • Hydrocarbon derivative
  • Primary alcohol
  • Organooxygen compound
  • Organonitrogen compound
  • Organochloride
  • Organohalogen compound
  • Amine
  • Alcohol
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External DescriptorsNot Available
Pharmacology
IndicationFor symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
PharmacodynamicsHydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.
Mechanism of actionHydroxyzine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The sedative properties of hydroxyzine occur at the subcortical level of the CNS. Secondary to its central anticholinergic actions, hydroxyzine may be effective as an antiemetic.
Related Articles
AbsorptionRapidly absorbed from the gastrointestinal tract
Volume of distributionNot Available
Protein binding93%
Metabolism

Hepatic

Route of eliminationNot Available
Half life20 to 25 hours
ClearanceNot Available
ToxicityOral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.8623
Blood Brain Barrier+0.9516
Caco-2 permeable-0.5565
P-glycoprotein substrateSubstrate0.7447
P-glycoprotein inhibitor IInhibitor0.8563
P-glycoprotein inhibitor IIInhibitor0.6394
Renal organic cation transporterInhibitor0.592
CYP450 2C9 substrateNon-substrate0.8352
CYP450 2D6 substrateNon-substrate0.9116
CYP450 3A4 substrateNon-substrate0.7193
CYP450 1A2 substrateNon-inhibitor0.9045
CYP450 2C9 inhibitorNon-inhibitor0.9111
CYP450 2D6 inhibitorInhibitor0.8535
CYP450 2C19 inhibitorNon-inhibitor0.9026
CYP450 3A4 inhibitorNon-inhibitor0.9623
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.7615
Ames testNon AMES toxic0.7558
CarcinogenicityNon-carcinogens0.9102
BiodegradationNot ready biodegradable1.0
Rat acute toxicity2.6612 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.5929
hERG inhibition (predictor II)Inhibitor0.7898
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Baxter healthcare corp anesthesia and critical care
  • Altana inc
  • App pharmaceuticals llc
  • Hospira inc
  • Luitpold pharmaceuticals inc
  • Pharmafair inc
  • Smith and nephew solopak div smith and nephew
  • Solopak medical products inc
  • Solopak laboratories inc
  • Watson laboratories inc
  • Wyeth ayerst laboratories
  • Organon usa inc
  • Pfizer laboratories div pfizer inc
  • Roerig div pfizer inc
  • Actavis mid atlantic llc
  • Alpharma us pharmaceuticals division
  • Hi tech pharmacal co inc
  • Kv pharmaceutical co
  • Vintage pharmaceuticals inc
  • Wockhardt eu operations (swiss) ag
  • Pfizer inc
  • Able laboratories inc
  • Actavis totowa llc
  • Amneal pharmaceutical
  • Halsey drug co inc
  • Heritage pharmaceuticals inc
  • Hetero drugs ltd unit iii
  • Invagen pharmaceuticals inc
  • Ivax pharmaceuticals inc
  • Kvk tech inc
  • Mutual pharmaceutical co inc
  • Mylan pharmaceuticals inc
  • Northstar healthcare holdings ltd
  • Pliva inc
  • Purepac pharmaceutical co
  • Quantum pharmics ltd
  • Sandoz inc
  • Sun pharmaceutical industries inc
  • Superpharm corp
  • Usl pharma inc
  • Vintage pharmaceuticals llc
  • Barr laboratories inc
  • Duramed pharmaceuticals inc sub barr laboratories inc
  • Ivax pharmaceuticals inc sub teva pharmaceuticals usa
  • Par pharmaceutical inc
  • Vangard laboratories inc div midway medical co
  • Teva pharmaceuticals usa inc
Packagers
Dosage forms
FormRouteStrength
Capsuleoral10 mg
Capsuleoral25 mg
Capsuleoral50 mg
Solutionintramuscular50 mg
Syruporal2 mg
Injection, solutionintramuscular25 mg/mL
Injection, solutionintramuscular50 mg/mL
Solutionoral10 mg/5mL
Syruporal10 mg/5mL
Tabletoral10 mg/1
Tabletoral25 mg/1
Tabletoral50 mg/1
Tablet, film coatedoral10 mg/1
Tablet, film coatedoral25 mg/1
Tablet, film coatedoral50 mg/1
Liquidintramuscular50 mg
Capsuleoral100 mg/1
Syruporal10 mg
Capsuleoral25 mg/1
Capsuleoral50 mg/1
Solutionintramuscular50 mg/mL
Prices
Unit descriptionCostUnit
Hydroxyzine Hcl 50 mg/ml4.42USD ml
Hydroxyzine 50 mg/ml vial3.96USD ml
Hydroxyzine 25 mg/ml vial3.6USD ml
Hydroxyzine hcl powder2.75USD g
Hydroxyzine pamoate powder2.14USD g
Vistaril 50 mg capsule2.03USD capsule
HydrOXYzine HCl 50 mg/ml vial1.78USD vial
Vistaril 25 mg capsule1.71USD capsule
Vistaril 100 mg capsule1.7USD capsule
Hydroxyzine hcl 50 mg tablet1.19USD tablet
Hydroxyzine hcl 10 mg tablet0.72USD tablet
Hydroxyzine hcl 25 mg tablet0.7USD tablet
HydrOXYzine Pamoate 100 mg capsule0.67USD capsule
Hydroxyzine pam 50 mg capsule0.64USD capsule
Hydroxyzine pam 100 mg capsule0.63USD capsule
Hydroxyzine pam 25 mg capsule0.46USD capsule
Vistaril 25 mg/5ml Suspension0.45USD ml
HydrOXYzine Pamoate 25 mg capsule0.3USD capsule
HydrOXYzine Pamoate 50 mg capsule0.23USD capsule
Apo-Hydroxyzine 50 mg Capsule0.22USD capsule
Novo-Hydroxyzin 50 mg Capsule0.22USD capsule
Apo-Hydroxyzine 25 mg Capsule0.15USD capsule
Novo-Hydroxyzin 25 mg Capsule0.15USD capsule
HydrOXYzine HCl 10 mg/5ml Syrup0.13USD ml
Apo-Hydroxyzine 10 mg Capsule0.12USD capsule
Novo-Hydroxyzin 10 mg Capsule0.12USD capsule
Atarax 2 mg/ml Syrup0.06USD ml
Pms-Hydroxyzine 2 mg/ml Syrup0.04USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point193 °CU.S. Patent 2,899,436.
water solubility< 700 mg/mLNot Available
logP2.7Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0914 mg/mLALOGPS
logP3.43ALOGPS
logP3.41ChemAxon
logS-3.6ALOGPS
pKa (Strongest Acidic)15.12ChemAxon
pKa (Strongest Basic)7.82ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area35.94 Å2ChemAxon
Rotatable Bond Count8ChemAxon
Refractivity107.07 m3·mol-1ChemAxon
Polarizability41.99 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
MSMass Spectrum (Electron Ionization)splash10-0uxr-4591000000-d2e3424c44feae8a5d9cView in MoNA
References
Synthesis Reference

U.S. Patent 2,899,436.

General References
  1. HUTCHEON DE, MORRIS DL, SCRIABINE A: Cardiovascular action of hydroxyzine (atarax). J Pharmacol Exp Ther. 1956 Dec;118(4):451-60. [PubMed:13385806 ]
  2. DOLAN CM: Management of emotional disturbances; use of hydroxyzine (atarax) in general practice. Calif Med. 1958 Jun;88(6):443-4. [PubMed:13536863 ]
  3. Clark BG, Araki M, Brown HW: Hydroxyzine-associated tardive dyskinesia. Ann Neurol. 1982 Apr;11(4):435. [PubMed:7103423 ]
External Links
ATC CodesN05BB51N05BB01
AHFS Codes
  • 28:24.92
PDB EntriesNot Available
FDA labelNot Available
MSDSDownload (73.5 KB)
Interactions
Drug Interactions
Drug
3,4-Methylenedioxyamphetamine3,4-Methylenedioxyamphetamine may decrease the sedative activities of Hydroxyzine.
3,4-Methylenedioxymethamphetamine3,4-Methylenedioxymethamphetamine may decrease the sedative activities of Hydroxyzine.
7-NitroindazoleHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of 7-Nitroindazole.
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Hydroxyzine.
AcepromazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Acepromazine.
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Hydroxyzine.
AceprometazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Aceprometazine.
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Hydroxyzine.
adipiplonHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of adipiplon.
adipiplonThe risk or severity of adverse effects can be increased when adipiplon is combined with Hydroxyzine.
AgomelatineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Agomelatine.
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Hydroxyzine.
AlfaxaloneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Alfaxalone.
AlfaxaloneThe risk or severity of adverse effects can be increased when Alfaxalone is combined with Hydroxyzine.
AlfentanilHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Alfentanil.
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Hydroxyzine.
AlphacetylmethadolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Alphacetylmethadol.
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Hydroxyzine.
AlprazolamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Alprazolam.
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Hydroxyzine.
AmiodaroneHydroxyzine may increase the QTc-prolonging activities of Amiodarone.
AmisulprideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Amisulpride.
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Hydroxyzine.
AmitriptylineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Amitriptyline.
AmitriptylineThe risk or severity of adverse effects can be increased when Amitriptyline is combined with Hydroxyzine.
AmobarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Amobarbital.
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with Hydroxyzine.
AmoxapineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Amoxapine.
AmoxapineThe risk or severity of adverse effects can be increased when Amoxapine is combined with Hydroxyzine.
AmperozideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Amperozide.
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Hydroxyzine.
AmphetamineAmphetamine may decrease the sedative activities of Hydroxyzine.
AnagrelideHydroxyzine may increase the QTc-prolonging activities of Anagrelide.
AripiprazoleThe serum concentration of Aripiprazole can be increased when it is combined with Hydroxyzine.
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with Hydroxyzine.
Arsenic trioxideHydroxyzine may increase the QTc-prolonging activities of Arsenic trioxide.
ArtemetherHydroxyzine may increase the QTc-prolonging activities of Artemether.
ArticaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Articaine.
ArticaineThe risk or severity of adverse effects can be increased when Articaine is combined with Hydroxyzine.
AsenapineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Asenapine.
AsenapineThe risk or severity of adverse effects can be increased when Asenapine is combined with Hydroxyzine.
AzaperoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Azaperone.
AzaperoneThe risk or severity of adverse effects can be increased when Azaperone is combined with Hydroxyzine.
AzelastineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
AzelastineThe risk or severity of adverse effects can be increased when Azelastine is combined with Hydroxyzine.
AzithromycinHydroxyzine may increase the QTc-prolonging activities of Azithromycin.
BaclofenHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Hydroxyzine.
BarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Barbital.
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with Hydroxyzine.
BedaquilineHydroxyzine may increase the QTc-prolonging activities of Bedaquiline.
BenzocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Benzocaine.
BenzocaineThe risk or severity of adverse effects can be increased when Benzocaine is combined with Hydroxyzine.
BenzphetamineBenzphetamine may decrease the sedative activities of Hydroxyzine.
Benzyl alcoholHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Benzyl alcohol.
Benzyl alcoholThe risk or severity of adverse effects can be increased when Benzyl alcohol is combined with Hydroxyzine.
Benzylpenicilloyl PolylysineHydroxyzine may decrease effectiveness of Benzylpenicilloyl Polylysine as a diagnostic agent.
BetahistineThe therapeutic efficacy of Betahistine can be decreased when used in combination with Hydroxyzine.
BrexpiprazoleHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Brexpiprazole.
BrexpiprazoleThe risk or severity of adverse effects can be increased when Brexpiprazole is combined with Hydroxyzine.
BrimonidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Brimonidine.
BromazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Bromazepam.
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Hydroxyzine.
BrompheniramineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Brompheniramine.
BrompheniramineThe risk or severity of adverse effects can be increased when Brompheniramine is combined with Hydroxyzine.
BrotizolamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Brotizolam.
BrotizolamThe risk or severity of adverse effects can be increased when Brotizolam is combined with Hydroxyzine.
BupivacaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Bupivacaine.
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Hydroxyzine.
BuprenorphineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
BuprenorphineThe risk or severity of adverse effects can be increased when Buprenorphine is combined with Hydroxyzine.
BuspironeHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Buspirone.
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Hydroxyzine.
ButabarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Butabarbital.
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Hydroxyzine.
ButacaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Butacaine.
ButacaineThe risk or severity of adverse effects can be increased when Butacaine is combined with Hydroxyzine.
ButalbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Butalbital.
ButalbitalThe risk or severity of adverse effects can be increased when Butalbital is combined with Hydroxyzine.
ButambenHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Butamben.
ButambenThe risk or severity of adverse effects can be increased when Butamben is combined with Hydroxyzine.
ButethalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Butethal.
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Hydroxyzine.
ButorphanolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Butorphanol.
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Hydroxyzine.
CarbamazepineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Carbamazepine.
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with Hydroxyzine.
CarbinoxamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Carbinoxamine.
CarbinoxamineThe risk or severity of adverse effects can be increased when Carbinoxamine is combined with Hydroxyzine.
CarfentanilHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Carfentanil.
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Hydroxyzine.
CarisoprodolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Carisoprodol.
CarisoprodolThe risk or severity of adverse effects can be increased when Carisoprodol is combined with Hydroxyzine.
CeritinibHydroxyzine may increase the QTc-prolonging activities of Ceritinib.
CetirizineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cetirizine.
CetirizineThe risk or severity of adverse effects can be increased when Cetirizine is combined with Hydroxyzine.
Chloral hydrateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chloral hydrate.
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Hydroxyzine.
ChlordiazepoxideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Hydroxyzine.
ChlormezanoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chlormezanone.
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with Hydroxyzine.
ChloroprocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chloroprocaine.
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with Hydroxyzine.
ChloroquineHydroxyzine may increase the QTc-prolonging activities of Chloroquine.
ChlorphenamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chlorphenamine.
ChlorphenamineThe risk or severity of adverse effects can be increased when Chlorphenamine is combined with Hydroxyzine.
ChlorphentermineChlorphentermine may decrease the sedative activities of Hydroxyzine.
ChlorpromazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chlorpromazine.
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Hydroxyzine.
ChlorprothixeneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chlorprothixene.
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Hydroxyzine.
ChlorzoxazoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Chlorzoxazone.
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Hydroxyzine.
CinchocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cinchocaine.
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Hydroxyzine.
CiprofloxacinHydroxyzine may increase the QTc-prolonging activities of Ciprofloxacin.
CisaprideHydroxyzine may increase the QTc-prolonging activities of Cisapride.
CitalopramThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Citalopram.
ClarithromycinHydroxyzine may increase the QTc-prolonging activities of Clarithromycin.
ClemastineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clemastine.
ClemastineThe risk or severity of adverse effects can be increased when Clemastine is combined with Hydroxyzine.
ClidiniumHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clidinium.
ClidiniumThe risk or severity of adverse effects can be increased when Clidinium is combined with Hydroxyzine.
ClobazamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clobazam.
ClobazamThe risk or severity of adverse effects can be increased when Clobazam is combined with Hydroxyzine.
clomethiazoleHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of clomethiazole.
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Hydroxyzine.
ClomipramineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clomipramine.
ClomipramineThe risk or severity of adverse effects can be increased when Clomipramine is combined with Hydroxyzine.
ClonazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clonazepam.
ClonazepamThe risk or severity of adverse effects can be increased when Clonazepam is combined with Hydroxyzine.
ClonidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clonidine.
ClonidineThe risk or severity of adverse effects can be increased when Clonidine is combined with Hydroxyzine.
ClorazepateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clorazepate.
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Hydroxyzine.
ClozapineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Clozapine.
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Hydroxyzine.
CocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cocaine.
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Hydroxyzine.
CodeineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Codeine.
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Hydroxyzine.
CrizotinibHydroxyzine may increase the QTc-prolonging activities of Crizotinib.
CyclizineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cyclizine.
CyclizineThe risk or severity of adverse effects can be increased when Cyclizine is combined with Hydroxyzine.
CyclobenzaprineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cyclobenzaprine.
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Hydroxyzine.
CyproheptadineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
CyproheptadineThe risk or severity of adverse effects can be increased when Cyproheptadine is combined with Hydroxyzine.
DantroleneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dantrolene.
DantroleneThe risk or severity of adverse effects can be increased when Dantrolene is combined with Hydroxyzine.
DapiprazoleHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dapiprazole.
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Hydroxyzine.
DapoxetineThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Dapoxetine.
deramciclaneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of deramciclane.
deramciclaneThe risk or severity of adverse effects can be increased when deramciclane is combined with Hydroxyzine.
DesfluraneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Desflurane.
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Hydroxyzine.
DesipramineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Desipramine.
DesipramineThe risk or severity of adverse effects can be increased when Desipramine is combined with Hydroxyzine.
DesloratadineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Desloratadine.
DesloratadineThe risk or severity of adverse effects can be increased when Desloratadine is combined with Hydroxyzine.
DetomidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Detomidine.
DetomidineThe risk or severity of adverse effects can be increased when Detomidine is combined with Hydroxyzine.
DexbrompheniramineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dexbrompheniramine.
DexbrompheniramineThe risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Hydroxyzine.
DexmedetomidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dexmedetomidine.
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Hydroxyzine.
DextroamphetamineDextroamphetamine may decrease the sedative activities of Hydroxyzine.
DextromoramideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dextromoramide.
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Hydroxyzine.
DextropropoxypheneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dextropropoxyphene.
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Hydroxyzine.
DezocineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dezocine.
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Hydroxyzine.
DiazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Diazepam.
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Hydroxyzine.
DifenoxinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Difenoxin.
DifenoxinThe risk or severity of adverse effects can be increased when Difenoxin is combined with Hydroxyzine.
DihydrocodeineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dihydrocodeine.
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Hydroxyzine.
DihydroetorphineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dihydroetorphine.
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Hydroxyzine.
DihydromorphineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dihydromorphine.
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Hydroxyzine.
DimenhydrinateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dimenhydrinate.
DimenhydrinateThe risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Hydroxyzine.
DiphenhydramineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Diphenhydramine.
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Hydroxyzine.
DiphenoxylateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Diphenoxylate.
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Hydroxyzine.
DisopyramideHydroxyzine may increase the QTc-prolonging activities of Disopyramide.
DofetilideHydroxyzine may increase the QTc-prolonging activities of Dofetilide.
DolasetronHydroxyzine may increase the QTc-prolonging activities of Dolasetron.
DomperidoneHydroxyzine may increase the QTc-prolonging activities of Domperidone.
DoramectinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Doramectin.
DoramectinThe risk or severity of adverse effects can be increased when Doramectin is combined with Hydroxyzine.
DoxepinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
DoxepinThe risk or severity of adverse effects can be increased when Doxepin is combined with Hydroxyzine.
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Hydroxyzine.
DPDPEHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of DPDPE.
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Hydroxyzine.
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Hydroxyzine.
DronedaroneHydroxyzine may increase the QTc-prolonging activities of Dronedarone.
DroperidolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Droperidol.
DroperidolThe risk or severity of adverse effects can be increased when Droperidol is combined with Hydroxyzine.
DrotebanolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Drotebanol.
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Hydroxyzine.
DyclonineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Dyclonine.
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Hydroxyzine.
EcgonineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ecgonine.
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with Hydroxyzine.
ECGONINE METHYL ESTERHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
ECGONINE METHYL ESTERThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Hydroxyzine.
EfavirenzHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Efavirenz.
EfavirenzThe risk or severity of adverse effects can be increased when Efavirenz is combined with Hydroxyzine.
EliglustatHydroxyzine may increase the QTc-prolonging activities of Eliglustat.
EnfluraneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Enflurane.
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Hydroxyzine.
EntacaponeHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Entacapone.
EntacaponeThe risk or severity of adverse effects can be increased when Entacapone is combined with Hydroxyzine.
ErythromycinHydroxyzine may increase the QTc-prolonging activities of Erythromycin.
EscitalopramThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Escitalopram.
EstazolamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Estazolam.
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Hydroxyzine.
EszopicloneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Eszopiclone.
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Hydroxyzine.
EthanolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
EthanolThe risk or severity of adverse effects can be increased when Ethanol is combined with Hydroxyzine.
EthchlorvynolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ethchlorvynol.
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Hydroxyzine.
EthosuximideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ethosuximide.
EthosuximideThe risk or severity of adverse effects can be increased when Ethosuximide is combined with Hydroxyzine.
EthotoinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ethotoin.
EthotoinThe risk or severity of adverse effects can be increased when Ethotoin is combined with Hydroxyzine.
Ethyl carbamateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ethyl carbamate.
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Hydroxyzine.
Ethyl loflazepateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ethyl loflazepate.
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Hydroxyzine.
EthylmorphineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ethylmorphine.
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Hydroxyzine.
EtidocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Etidocaine.
EtidocaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Hydroxyzine.
EtifoxineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Etifoxine.
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Hydroxyzine.
EtizolamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Etizolam.
EtizolamThe risk or severity of adverse effects can be increased when Etizolam is combined with Hydroxyzine.
EtomidateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Etomidate.
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Hydroxyzine.
EtoperidoneThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Etoperidone.
EtorphineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Etorphine.
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with Hydroxyzine.
EzogabineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ezogabine.
EzogabineThe risk or severity of adverse effects can be increased when Ezogabine is combined with Hydroxyzine.
FelbamateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Felbamate.
FelbamateThe risk or severity of adverse effects can be increased when Felbamate is combined with Hydroxyzine.
FencamfamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fencamfamine.
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Hydroxyzine.
FenfluramineThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Fenfluramine.
FentanylHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fentanyl.
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Hydroxyzine.
FesoterodineThe serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Hydroxyzine.
FexofenadineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fexofenadine.
FexofenadineThe risk or severity of adverse effects can be increased when Fexofenadine is combined with Hydroxyzine.
FlecainideHydroxyzine may increase the QTc-prolonging activities of Flecainide.
FlibanserinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Flibanserin.
FlibanserinThe risk or severity of adverse effects can be increased when Flibanserin is combined with Hydroxyzine.
FludiazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fludiazepam.
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Hydroxyzine.
FlunarizineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Flunarizine.
FlunarizineThe risk or severity of adverse effects can be increased when Flunarizine is combined with Hydroxyzine.
FlunitrazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Flunitrazepam.
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Hydroxyzine.
FluoxetineThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Fluoxetine.
FlupentixolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Flupentixol.
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Hydroxyzine.
FluphenazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Hydroxyzine.
FlurazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Flurazepam.
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Hydroxyzine.
FluspirileneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fluspirilene.
FluspirileneThe risk or severity of adverse effects can be increased when Fluspirilene is combined with Hydroxyzine.
Fluticasone PropionateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fluticasone Propionate.
Fluticasone PropionateThe risk or severity of adverse effects can be increased when Fluticasone Propionate is combined with Hydroxyzine.
FluvoxamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fluvoxamine.
FluvoxamineThe risk or severity of adverse effects can be increased when Fluvoxamine is combined with Hydroxyzine.
FosphenytoinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fosphenytoin.
FosphenytoinThe risk or severity of adverse effects can be increased when Fosphenytoin is combined with Hydroxyzine.
FospropofolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Fospropofol.
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Hydroxyzine.
GabapentinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Hydroxyzine.
gabapentin enacarbilHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of gabapentin enacarbil.
gabapentin enacarbilThe risk or severity of adverse effects can be increased when gabapentin enacarbil is combined with Hydroxyzine.
Gadobenic acidHydroxyzine may increase the QTc-prolonging activities of Gadobenic acid.
Gamma Hydroxybutyric AcidHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Gamma Hydroxybutyric Acid.
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Hydroxyzine.
GemifloxacinHydroxyzine may increase the QTc-prolonging activities of Gemifloxacin.
GlutethimideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Glutethimide.
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Hydroxyzine.
GoserelinHydroxyzine may increase the QTc-prolonging activities of Goserelin.
GranisetronHydroxyzine may increase the QTc-prolonging activities of Granisetron.
GuanfacineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Guanfacine.
GuanfacineThe risk or severity of adverse effects can be increased when Guanfacine is combined with Hydroxyzine.
HalazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Halazepam.
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Hydroxyzine.
HaloperidolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Haloperidol.
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Hydroxyzine.
HalothaneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Halothane.
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Hydroxyzine.
HeroinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Heroin.
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Hydroxyzine.
HexobarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Hexobarbital.
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with Hydroxyzine.
HyaluronidaseThe therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Hydroxyzine.
HydrocodoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
HydrocodoneThe risk or severity of adverse effects can be increased when Hydrocodone is combined with Hydroxyzine.
HydromorphoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Hydromorphone.
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Hydroxyzine.
Hydroxyamphetamine hydrobromideHydroxyamphetamine hydrobromide may decrease the sedative activities of Hydroxyzine.
IbutilideHydroxyzine may increase the QTc-prolonging activities of Ibutilide.
IloperidoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Iloperidone.
IloperidoneThe risk or severity of adverse effects can be increased when Iloperidone is combined with Hydroxyzine.
ImipramineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Imipramine.
ImipramineThe risk or severity of adverse effects can be increased when Imipramine is combined with Hydroxyzine.
IndalpineThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Indalpine.
IsofluraneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Isoflurane.
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Hydroxyzine.
KetamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ketamine.
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Hydroxyzine.
KetazolamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ketazolam.
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Hydroxyzine.
KetobemidoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ketobemidone.
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Hydroxyzine.
LamotrigineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lamotrigine.
LamotrigineThe risk or severity of adverse effects can be increased when Lamotrigine is combined with Hydroxyzine.
LenvatinibHydroxyzine may increase the QTc-prolonging activities of Lenvatinib.
LeuprolideHydroxyzine may increase the QTc-prolonging activities of Leuprolide.
LevetiracetamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Levetiracetam.
LevetiracetamThe risk or severity of adverse effects can be increased when Levetiracetam is combined with Hydroxyzine.
LevobupivacaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Levobupivacaine.
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Hydroxyzine.
LevocabastineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Levocabastine.
LevocabastineThe risk or severity of adverse effects can be increased when Levocabastine is combined with Hydroxyzine.
LevocetirizineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Levocetirizine.
LevocetirizineThe risk or severity of adverse effects can be increased when Levocetirizine is combined with Hydroxyzine.
LevodopaHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Levodopa.
LevodopaThe risk or severity of adverse effects can be increased when Levodopa is combined with Hydroxyzine.
LevofloxacinHydroxyzine may increase the QTc-prolonging activities of Levofloxacin.
Levomethadyl AcetateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Levomethadyl Acetate.
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Hydroxyzine.
LevomilnacipranThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Levomilnacipran.
LevorphanolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Levorphanol.
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Hydroxyzine.
LidocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lidocaine.
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with Hydroxyzine.
LisdexamfetamineLisdexamfetamine may decrease the sedative activities of Hydroxyzine.
LithiumHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lithium.
LithiumThe risk or severity of adverse effects can be increased when Lithium is combined with Hydroxyzine.
LofentanilHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lofentanil.
LofentanilThe risk or severity of adverse effects can be increased when Lofentanil is combined with Hydroxyzine.
LopinavirHydroxyzine may increase the QTc-prolonging activities of Lopinavir.
LoratadineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Loratadine.
LoratadineThe risk or severity of adverse effects can be increased when Loratadine is combined with Hydroxyzine.
LorazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lorazepam.
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Hydroxyzine.
LoxapineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Loxapine.
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Hydroxyzine.
Lu AA21004Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lu AA21004.
Lu AA21004The risk or severity of adverse effects can be increased when Lu AA21004 is combined with Hydroxyzine.
LumefantrineHydroxyzine may increase the QTc-prolonging activities of Lumefantrine.
LurasidoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Lurasidone.
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Hydroxyzine.
Magnesium SulfateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Magnesium Sulfate.
MaprotilineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Maprotiline.
MaprotilineThe risk or severity of adverse effects can be increased when Maprotiline is combined with Hydroxyzine.
MeclizineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Meclizine.
MeclizineThe risk or severity of adverse effects can be increased when Meclizine is combined with Hydroxyzine.
MedetomidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Medetomidine.
MedetomidineThe risk or severity of adverse effects can be increased when Medetomidine is combined with Hydroxyzine.
MelatoninHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Melatonin.
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Hydroxyzine.
MelperoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Melperone.
MelperoneThe risk or severity of adverse effects can be increased when Melperone is combined with Hydroxyzine.
MephentermineMephentermine may decrease the sedative activities of Hydroxyzine.
MepivacaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Mepivacaine.
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Hydroxyzine.
MeprobamateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Meprobamate.
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Hydroxyzine.
MesoridazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine.
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Hydroxyzine.
MetaxaloneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Metaxalone.
MetaxaloneThe risk or severity of adverse effects can be increased when Metaxalone is combined with Hydroxyzine.
MethadoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methadone.
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Hydroxyzine.
Methadyl AcetateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methadyl Acetate.
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Hydroxyzine.
MethamphetamineMethamphetamine may decrease the sedative activities of Hydroxyzine.
MethapyrileneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methapyrilene.
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Hydroxyzine.
MethaqualoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methaqualone.
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Hydroxyzine.
MethocarbamolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methocarbamol.
MethocarbamolThe risk or severity of adverse effects can be increased when Methocarbamol is combined with Hydroxyzine.
MethohexitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methohexital.
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Hydroxyzine.
MethotrimeprazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
MethotrimeprazineThe risk or severity of adverse effects can be increased when Methotrimeprazine is combined with Hydroxyzine.
MethoxyfluraneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methoxyflurane.
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Hydroxyzine.
MethsuximideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methsuximide.
MethsuximideThe risk or severity of adverse effects can be increased when Methsuximide is combined with Hydroxyzine.
MethylphenobarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital.
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Hydroxyzine.
MetoprololThe serum concentration of Metoprolol can be increased when it is combined with Hydroxyzine.
MetyrosineHydroxyzine may increase the sedative activities of Metyrosine.
MidazolamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Midazolam.
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Hydroxyzine.
MifepristoneMifepristone may increase the QTc-prolonging activities of Hydroxyzine.
MilnacipranThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Milnacipran.
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Hydroxyzine.
MirtazapineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
MirtazapineThe risk or severity of adverse effects can be increased when Mirtazapine is combined with Hydroxyzine.
MolindoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Molindone.
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Hydroxyzine.
MorphineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Morphine.
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Hydroxyzine.
MoxifloxacinHydroxyzine may increase the QTc-prolonging activities of Moxifloxacin.
NabiloneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Nabilone.
NalbuphineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Nalbuphine.
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Hydroxyzine.
NilotinibHydroxyzine may increase the QTc-prolonging activities of Nilotinib.
NitrazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Nitrazepam.
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Hydroxyzine.
Nitrous oxideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Nitrous oxide.
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Hydroxyzine.
NormethadoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Normethadone.
NormethadoneThe risk or severity of adverse effects can be increased when Normethadone is combined with Hydroxyzine.
NortriptylineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Nortriptyline.
NortriptylineThe risk or severity of adverse effects can be increased when Nortriptyline is combined with Hydroxyzine.
OfloxacinHydroxyzine may increase the QTc-prolonging activities of Ofloxacin.
OlanzapineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
OlanzapineThe risk or severity of adverse effects can be increased when Olanzapine is combined with Hydroxyzine.
OlopatadineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Olopatadine.
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Hydroxyzine.
OndansetronHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Hydroxyzine.
OpiumHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Opium.
OpiumThe risk or severity of adverse effects can be increased when Opium is combined with Hydroxyzine.
OrphenadrineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
OrphenadrineThe risk or severity of adverse effects can be increased when Orphenadrine is combined with Hydroxyzine.
OsanetantHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Osanetant.
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Hydroxyzine.
OxazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Oxazepam.
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Hydroxyzine.
OxprenololHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Oxprenolol.
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Hydroxyzine.
OxybuprocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Oxybuprocaine.
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Hydroxyzine.
OxycodoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Oxycodone.
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Hydroxyzine.
OxymorphoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Oxymorphone.
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with Hydroxyzine.
PaliperidoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Paliperidone.
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with Hydroxyzine.
PanobinostatHydroxyzine may increase the QTc-prolonging activities of Panobinostat.
ParaldehydeHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ParaldehydeThe risk or severity of adverse effects can be increased when Paraldehyde is combined with Hydroxyzine.
ParoxetineThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Paroxetine.
PazopanibHydroxyzine may increase the QTc-prolonging activities of Pazopanib.
PentamidineHydroxyzine may increase the QTc-prolonging activities of Pentamidine.
PentazocineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pentazocine.
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Hydroxyzine.
PentobarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pentobarbital.
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Hydroxyzine.
PerampanelHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Perampanel.
PerampanelThe risk or severity of adverse effects can be increased when Perampanel is combined with Hydroxyzine.
PerflutrenHydroxyzine may increase the QTc-prolonging activities of Perflutren.
PerospironeHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Perospirone.
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Hydroxyzine.
PerphenazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Perphenazine.
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Hydroxyzine.
PethidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pethidine.
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Hydroxyzine.
PhenobarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Phenobarbital.
PhenobarbitalThe risk or severity of adverse effects can be increased when Phenobarbital is combined with Hydroxyzine.
PhenoxyethanolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Phenoxyethanol.
PhenoxyethanolThe risk or severity of adverse effects can be increased when Phenoxyethanol is combined with Hydroxyzine.
PhenterminePhentermine may decrease the sedative activities of Hydroxyzine.
PhenytoinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Phenytoin.
PhenytoinThe risk or severity of adverse effects can be increased when Phenytoin is combined with Hydroxyzine.
PimozideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pimozide.
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Hydroxyzine.
PipamperoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pipamperone.
PipamperoneThe risk or severity of adverse effects can be increased when Pipamperone is combined with Hydroxyzine.
PipotiazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pipotiazine.
PipotiazineThe risk or severity of adverse effects can be increased when Pipotiazine is combined with Hydroxyzine.
PizotifenHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.
PizotifenThe risk or severity of adverse effects can be increased when Pizotifen is combined with Hydroxyzine.
PomalidomideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pomalidomide.
PomalidomideThe risk or severity of adverse effects can be increased when Pomalidomide is combined with Hydroxyzine.
PramipexoleHydroxyzine may increase the sedative activities of Pramipexole.
PramocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pramocaine.
PramocaineThe risk or severity of adverse effects can be increased when Pramocaine is combined with Hydroxyzine.
PrazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Prazepam.
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Hydroxyzine.
PregabalinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pregabalin.
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Hydroxyzine.
PrilocaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Hydroxyzine.
PrimaquineHydroxyzine may increase the QTc-prolonging activities of Primaquine.
PrimidoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Primidone.
PrimidoneThe risk or severity of adverse effects can be increased when Primidone is combined with Hydroxyzine.
ProcainamideHydroxyzine may increase the QTc-prolonging activities of Procainamide.
ProcaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Procaine.
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Hydroxyzine.
ProchlorperazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Prochlorperazine.
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Hydroxyzine.
PromazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Promazine.
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Hydroxyzine.
PromethazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Promethazine.
PromethazineThe risk or severity of adverse effects can be increased when Promethazine is combined with Hydroxyzine.
PropafenoneHydroxyzine may increase the QTc-prolonging activities of Propafenone.
ProparacaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Proparacaine.
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Hydroxyzine.
PropofolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Propofol.
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Hydroxyzine.
PropoxycaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Propoxycaine.
PropoxycaineThe risk or severity of adverse effects can be increased when Propoxycaine is combined with Hydroxyzine.
ProtriptylineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Protriptyline.
ProtriptylineThe risk or severity of adverse effects can be increased when Protriptyline is combined with Hydroxyzine.
PSD502Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of PSD502.
PSD502The risk or severity of adverse effects can be increased when PSD502 is combined with Hydroxyzine.
QuazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Quazepam.
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Hydroxyzine.
QuetiapineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Quetiapine.
QuetiapineThe risk or severity of adverse effects can be increased when Quetiapine is combined with Hydroxyzine.
QuinidineHydroxyzine may increase the QTc-prolonging activities of Quinidine.
QuinineHydroxyzine may increase the QTc-prolonging activities of Quinine.
RamelteonHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ramelteon.
RamelteonThe risk or severity of adverse effects can be increased when Ramelteon is combined with Hydroxyzine.
RemifentanilHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Remifentanil.
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Hydroxyzine.
RemoxiprideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Remoxipride.
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Hydroxyzine.
ReserpineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Reserpine.
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Hydroxyzine.
RisperidoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Risperidone.
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Hydroxyzine.
RomifidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Romifidine.
RomifidineThe risk or severity of adverse effects can be increased when Romifidine is combined with Hydroxyzine.
RopiniroleHydroxyzine may increase the sedative activities of Ropinirole.
RopivacaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ropivacaine.
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Hydroxyzine.
RotigotineHydroxyzine may increase the sedative activities of Rotigotine.
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Hydroxyzine.
S-EthylisothioureaHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of S-Ethylisothiourea.
S-EthylisothioureaThe risk or severity of adverse effects can be increased when S-Ethylisothiourea is combined with Hydroxyzine.
SaquinavirHydroxyzine may increase the QTc-prolonging activities of Saquinavir.
ScopolamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Scopolamine.
ScopolamineThe risk or severity of adverse effects can be increased when Scopolamine is combined with Hydroxyzine.
SecobarbitalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Secobarbital.
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with Hydroxyzine.
SertindoleHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Sertindole.
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Hydroxyzine.
SertralineThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Sertraline.
SevofluraneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Sevoflurane.
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Hydroxyzine.
Sodium oxybateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Sodium oxybateThe risk or severity of adverse effects can be increased when Sodium oxybate is combined with Hydroxyzine.
SotalolHydroxyzine may increase the QTc-prolonging activities of Sotalol.
StiripentolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Stiripentol.
StiripentolThe risk or severity of adverse effects can be increased when Stiripentol is combined with Hydroxyzine.
SufentanilHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Sufentanil.
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Hydroxyzine.
SulfisoxazoleHydroxyzine may increase the QTc-prolonging activities of Sulfisoxazole.
SulpirideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Sulpiride.
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Hydroxyzine.
SuvorexantHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
SuvorexantThe risk or severity of adverse effects can be increased when Suvorexant is combined with Hydroxyzine.
TapentadolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tapentadol.
TapentadolThe risk or severity of adverse effects can be increased when Tapentadol is combined with Hydroxyzine.
TasimelteonHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tasimelteon.
TasimelteonThe risk or severity of adverse effects can be increased when Tasimelteon is combined with Hydroxyzine.
TelavancinHydroxyzine may increase the QTc-prolonging activities of Telavancin.
TelithromycinHydroxyzine may increase the QTc-prolonging activities of Telithromycin.
TemazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Temazepam.
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Hydroxyzine.
TetrabenazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tetrabenazine.
TetrabenazineThe risk or severity of adverse effects can be increased when Tetrabenazine is combined with Hydroxyzine.
TetracaineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tetracaine.
TetracaineThe risk or severity of adverse effects can be increased when Tetracaine is combined with Hydroxyzine.
TetrodotoxinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tetrodotoxin.
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Hydroxyzine.
ThalidomideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
ThalidomideThe risk or severity of adverse effects can be increased when Thalidomide is combined with Hydroxyzine.
ThiamylalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Thiamylal.
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with Hydroxyzine.
ThiopentalHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Thiopental.
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Hydroxyzine.
ThioridazineThe serum concentration of Thioridazine can be increased when it is combined with Hydroxyzine.
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Hydroxyzine.
ThiothixeneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Hydroxyzine.
TiagabineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tiagabine.
TiagabineThe risk or severity of adverse effects can be increased when Tiagabine is combined with Hydroxyzine.
TiletamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tiletamine.
TiletamineThe risk or severity of adverse effects can be increased when Tiletamine is combined with Hydroxyzine.
TizanidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tizanidine.
TizanidineThe risk or severity of adverse effects can be increased when Tizanidine is combined with Hydroxyzine.
TolcaponeHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tolcapone.
TolcaponeThe risk or severity of adverse effects can be increased when Tolcapone is combined with Hydroxyzine.
TopiramateHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Topiramate.
TopiramateThe risk or severity of adverse effects can be increased when Topiramate is combined with Hydroxyzine.
ToremifeneHydroxyzine may increase the QTc-prolonging activities of Toremifene.
TramadolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tramadol.
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Hydroxyzine.
Trans-2-PhenylcyclopropylamineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Trans-2-Phenylcyclopropylamine.
Trans-2-PhenylcyclopropylamineThe risk or severity of adverse effects can be increased when Trans-2-Phenylcyclopropylamine is combined with Hydroxyzine.
TranylcypromineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tranylcypromine.
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Hydroxyzine.
TrazodoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Trazodone.
TrazodoneThe risk or severity of adverse effects can be increased when Trazodone is combined with Hydroxyzine.
TriazolamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Triazolam.
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Hydroxyzine.
TrifluoperazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Trifluoperazine.
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Hydroxyzine.
TriflupromazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Triflupromazine.
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Hydroxyzine.
TrimipramineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Trimipramine.
TrimipramineThe risk or severity of adverse effects can be increased when Trimipramine is combined with Hydroxyzine.
TriprolidineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Triprolidine.
TriprolidineThe risk or severity of adverse effects can be increased when Triprolidine is combined with Hydroxyzine.
Valproic AcidHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Valproic Acid.
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Hydroxyzine.
VandetanibHydroxyzine may increase the QTc-prolonging activities of Vandetanib.
VemurafenibHydroxyzine may increase the QTc-prolonging activities of Vemurafenib.
VigabatrinHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Vigabatrin.
VigabatrinThe risk or severity of adverse effects can be increased when Vigabatrin is combined with Hydroxyzine.
VilazodoneThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Vilazodone.
VortioxetineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Vortioxetine.
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Hydroxyzine.
XylazineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Xylazine.
XylazineThe risk or severity of adverse effects can be increased when Xylazine is combined with Hydroxyzine.
YohimbineThe therapeutic efficacy of Hydroxyzine can be decreased when used in combination with Yohimbine.
ZaleplonHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zaleplon.
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Hydroxyzine.
ZiconotideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ziconotide.
ZiconotideThe risk or severity of adverse effects can be increased when Ziconotide is combined with Hydroxyzine.
ZimelidineThe risk or severity of adverse effects can be increased when Hydroxyzine is combined with Zimelidine.
ZiprasidoneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Ziprasidone.
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Hydroxyzine.
ZolazepamHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zolazepam.
ZolazepamThe risk or severity of adverse effects can be increased when Zolazepam is combined with Hydroxyzine.
ZolpidemHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
ZolpidemThe risk or severity of adverse effects can be increased when Zolpidem is combined with Hydroxyzine.
ZonisamideHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zonisamide.
ZonisamideThe risk or severity of adverse effects can be increased when Zonisamide is combined with Hydroxyzine.
ZopicloneHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zopiclone.
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Hydroxyzine.
ZotepineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zotepine.
ZotepineThe risk or severity of adverse effects can be increased when Zotepine is combined with Hydroxyzine.
ZuclopenthixolHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Zuclopenthixol.
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with Hydroxyzine.
Food Interactions
  • Avoid alcohol.
  • Take with food.

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
antagonist
General Function:
Histamine receptor activity
Specific Function:
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
Gene Name:
HRH1
Uniprot ID:
P35367
Molecular Weight:
55783.61 Da
References
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Spahr L, Coeytaux A, Giostra E, Hadengue A, Annoni JM: Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial. Am J Gastroenterol. 2007 Apr;102(4):744-53. Epub 2007 Jan 11. [PubMed:17222324 ]
  3. Sakaguchi T, Itoh H, Ding WG, Tsuji K, Nagaoka I, Oka Y, Ashihara T, Ito M, Yumoto Y, Zenda N, Higashi Y, Takeyama Y, Matsuura H, Horie M: Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation. J Pharmacol Sci. 2008 Dec;108(4):462-71. Epub 2008 Dec 5. [PubMed:19057127 ]
  4. Chen C: Physicochemical, pharmacological and pharmacokinetic properties of the zwitterionic antihistamines cetirizine and levocetirizine. Curr Med Chem. 2008;15(21):2173-91. [PubMed:18781943 ]
  5. Snowman AM, Snyder SH: Cetirizine: actions on neurotransmitter receptors. J Allergy Clin Immunol. 1990 Dec;86(6 Pt 2):1025-8. [PubMed:1979798 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
Gene Name:
CYP2D6
Uniprot ID:
P10635
Molecular Weight:
55768.94 Da
References
  1. Hamelin BA, Bouayad A, Drolet B, Gravel A, Turgeon J: In vitro characterization of cytochrome P450 2D6 inhibition by classic histamine H1 receptor antagonists. Drug Metab Dispos. 1998 Jun;26(6):536-9. [PubMed:9616188 ]
  2. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
  3. Drug Interactions: Cytochrome P450 Drug Interaction Table [Link]
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Drug created on June 13, 2005 07:24 / Updated on August 17, 2016 12:23