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Identification
NameMagnesium
Accession NumberDB01378
TypeSmall Molecule
GroupsNutraceutical
DescriptionMagnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents.
Structure
Thumb
SynonymsNot Available
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Mag-forcecapsule150 mgoralPrairie NaturalsNot applicableNot applicableCanada
Magnesium 250 mgtablet250 mgoralLeiner Health Products Inc.Not applicableNot applicableCanada
Magnesium Lactate Cap 70mgcapsule70 mgoralStandard Process Inc.Not applicableNot applicableCanada
Approved Generic Prescription ProductsNot Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Acti Mag 250 Caplettablet250 mgoralActi Form Ltd.1991-12-312005-03-21Canada
Chelated Magnesium 150mg - Tabtablet150 mgoralHealth Wise Nutrition Inc.1997-08-152000-07-29Canada
Chelated Magnesium Supplement - Tab 100mgtablet100 mgoralAlbion Laboratories Inc.1996-09-062007-10-19Canada
Chelated Magnesium Tab 50mgtablet50 mgoralJamieson Laboratories Ltd1975-12-312001-09-14Canada
Chelazome Magnesium 100mgtablet100 mgoralTrophic Canada Ltd.1987-12-312000-08-03Canada
F.M. Formulacapsule80 mgoralNature's Sunshine Products Of Canada Ltd.1999-05-252009-08-07Canada
Magneliscapsule165 mgoralImport Export SantÉ Nature Inc.1999-02-202003-08-01Canada
Magnesiumcapsule20 mgoralFrega Inc.1981-12-312008-02-13Canada
Magnesium - 100mg Tabtablet100 mgoralMetagenics, Inc.1997-02-012008-08-28Canada
Magnesium 150 mgcapsule150 mgoralPreferred Nutrition Inc.2004-05-122005-08-04Canada
Magnesium 150 mgcapsule150 mgoralRegime Industries Ltd.2002-08-282009-07-17Canada
Magnesium 250mg Tabtablet250 mgoralBioforce Canada Inc.1994-12-311997-07-22Canada
Magnesium Capcapsule72.5 mgoralLaboratoire Lalco Inc.1982-12-312001-10-15Canada
Magnesium Chelate 125mgcapsule125 mgoralHolista Health (Canada) Inc.2003-06-042008-07-17Canada
Magnesium Citramate Capcapsule150 mgoralThorne Research Inc.1997-04-182008-08-11Canada
Magnesium Citratecapsule250 mgoralSisu Inc.1998-01-012009-08-04Canada
Magnesium Citrate - Cap 100mgcapsule100 mgoralSisu Inc.1997-02-252009-08-04Canada
Magnesium Citrate - Cap 90mgcapsule90 mgoralProfessional Health Products1996-09-062000-08-29Canada
Magnesium Citrate 150mgcapsule150 mgoralWn Pharmaceuticals Ltd.2001-11-292008-07-17Canada
Magnesium Citrate Cap 150mgcapsule150 mgoralGahler Enterprises Ltd.1992-12-312008-07-17Canada
Magnesium Citrate Caplet 300mgtablet300 mgoralSwiss Herbal Remedies Ltd.1991-12-312009-08-04Canada
Magnesium Complex 250mgtablet250 mgoralJamieson Laboratories Ltd2004-03-012008-08-04Canada
Magnesium Dietary Supplementtablet100 mgoralGarden State Nutritionals1998-09-222000-06-07Canada
Magnesium Liq 114mg/15mlliquid114 mgoralInno Vite Incorporated1989-12-312007-07-31Canada
Magnesium Oxide Powder Heavypowder240 mgoralSwiss Herbal Remedies Ltd.1979-12-312003-09-10Canada
Magnesium Oxide Tab 252mgtablet252 mgoralLe Naturiste J.M.B. Inc.1990-12-311997-07-23Canada
Magnesium Oxide Tab 70mgtablet70 mgoralNutri West Products Ltd.1993-12-311997-08-05Canada
Magnesium Supplementsolution118.6 mgoralLand Art Inc.2003-07-212008-06-26Canada
Magnesium Tablets 200mgtablet200 mgoralRoyal Bodycare Canada Inc.1998-08-132005-08-02Canada
Magnesium-CLpowder119.6 mgoralVitavie Au Naturel 9023 3503 Quebec Inc.1997-10-142009-07-29Canada
Magnesium-CLliquid23.92 mgoralVitavie Au Naturel 9023 3503 Quebec Inc.1991-12-312009-07-29Canada
Magnesium-tabtablet250 mgoralNature's Sunshine Products Of Canada Ltd.1995-12-312008-07-31Canada
Magnex Liqliquid1 goralNatur Canada Inc.1971-12-311997-04-09Canada
Magnorol Cap 20mgcapsule20 mgoralRolmex International Inc.1975-12-312008-07-09Canada
Naturogene Tab 36mgtablet36 mgoralLe Naturiste J.M.B. Inc.1988-12-312000-08-23Canada
Phytesium Liq 10.24mg/mlliquid10.24 mgoralProduits Phyto Inc.1973-12-312003-11-27Canada
Port A Mins Super Magnesium 188tablet188 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Port A Mins Super Magnesium 375tablet375 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Slow-magtablet (enteric-coated)64 mgoralShire Pharma Canada Ulc1999-02-102002-02-28Canada
Slow-mag-tabtablet (enteric-coated)64 mgoralSearle Canada Unit Of Monsanto Canada Inc.1998-02-102000-07-19Canada
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Nmc Magma Mineral Packplaster3 g/100gtopicalNmc (Natural Magma Cosmetics)2013-07-08Not applicableUs
International BrandsNot Available
Brand mixtures
NameLabellerIngredients
Acetabolan III Vitamin and Mineral SupplementIovate Health Sciences International Inc.
Acetabolan-II Vitamin and Mineral SupplementIovate Health Sciences International Inc.
Acti-cal/mag 2:1 + Zinc and D CapletActi Form Ltd.
ActyformTechnodiet S.E.N.C.
AlphaligoClinique Lafontaine Inc, Division Les Importations Ortho
AminosynHospira, Inc.
Aminosyn 3.5% MAbbott Laboratories, Limited
ArmaxEnzymatic Therapy (Canada) Inc.
B & J Formula Dietary SupplementGarden State Nutritionals
B 6 PlusAnabolic Laboratories Inc.
BaisixProdemdis Enr.
BseltzerAbundance Marketing Ltd.
Buffered Vitamin C Plus MagnesiumTwin Laboratories Inc.
Buffered Vitamin C Powder With Ca Mg and KThorne Research Canada Ltd.
Buffered Vitamin C Pwr W Cal-mag-potassiumSisu Inc.
C-nate DHACenturion Labs, Llc
C.H.V. FormulaNihon Kenko Zoushin Kenkyukai Canada Inc., Subsidery Of Nikken Usa Inc.
C.R.T. X Multivitamin & Mineral Powder MixMetaform Ltd.
Cal & Mag Hvp Chel Plus C Potass & Zinc TabGahler Enterprises Ltd.
Cal M TabAnabolic Laboratories Inc.
Cal Mag Drink With Vitamin CWampole Brands
Cal Mag Plus - TabNutrilite, A Division Of Access Business Group, Llc
Cal Mag TabSwiss Herbal Remedies Ltd.
Cal-mag (one To One) With Potass & ZincGahler Enterprises Ltd.
Cal-mag Citrate Zinc & Vitamin D TabletsSwiss Herbal Remedies Ltd.
Cal-mag Complete With Zinc, C and DQuest Vitamins A Div Of Purity Life Health Products
Cal-mag Plus K, Mn and Zn CapletsHealth Wise Nutrition Inc.
Cal-mag TabletStandard Process Inc.
Cal-mag Vitamin C and Zinc TabSwiss Herbal Remedies Ltd.
Cal-mag With Vitamin DAlbi Imports Ltd.
Cal-mag With Zinc & Vitamin DHealth Wise Nutrition Inc.
Cal/mag 1:1 With Zinc and Vitamin D - TabletHealth Wise Nutrition Inc.
Cal/mag 2:1 With DWn Pharmaceuticals Ltd.
Cal/mag+dSeroyal International Inc.
Calci-yum Plus Magnesium + D3Nu Life Nutrition Ltd.
Calcimag TabLes Produits Naturels Suisse Inc.
Calcium Mg and Zn Capsules With Vitamin DRheingold Food International Ltd.
Calcium & Magnesium Citrate Plus D With Manganese, Potassium & ZincNatural Factors Nutritional Products Ltd.
Calcium & Magnesium Plus Potassium & ZincNatural Factors Nutritional Products Ltd.
Calcium & Magnesium Plus Potassium, Zinc, & ManganeseNatural Factors Nutritional Products Ltd.
Calcium & Magnesium TabBioforce Canada Inc.
Calcium & Magnesium TabletsVita Health Products Inc
Calcium & Magnesium With Potassium & ZincWn Pharmaceuticals Ltd.
Calcium & Magnesium With Potassium, Zinc, Manganese & Vitamin DWn Pharmaceuticals Ltd.
Calcium & Magnesium With Vitamin DOrganika Health Products Inc.
Calcium 400 With Magnesium - PwrHillestad Pharmaceuticals Usa
Calcium and Mag-potass and Zinc CapGahler Enterprises Ltd.
Calcium and Magnesium 1:1 Plus TabletsAlbi Naturals
Calcium and Magnesium Citrate and Vitamin D 250mg/125mg/200iuWn Pharmaceuticals Ltd.
Calcium and Magnesium Citrate With Vitamin DSisu Inc.
Calcium and Magnesium TabAlbi Imports Ltd.
Calcium and Magnesium TabletsVitazan Herbs & Vitamins Inc.
Calcium and Magnesium W Zinc TabPharmavite Llc
Calcium and Magnesium With Vitamin DVita Health Products Inc
Calcium and Magnesium With ZincVita Health Products Inc
Calcium Caps Plus MagnesiumTwin Laboratories Inc.
Calcium Capsules With Magnesium and Vitamin DHerba Lab Inc.
Calcium Et Magnesium Plus Vitamin DLaboratoire Lalco Inc.
Calcium Et Magnesium Plus Vitamine D/fe/znLaboratoire Lalco Inc.
Calcium Et Magnesium TabLaboratoire Lalco Inc.
Calcium Folic Acid Plus D ChewableAcella Pharmaceuticals, LLC
Calcium Lactate PowderStandard Process Inc.
Calcium Magnesium 1000/500 - TabPro Shop Inc.
Calcium Magnesium 2:1 Tablets With Vitamin DSisu Inc.
Calcium Magnesium Avec Vitamine CLes Aliments Nutri Source Inc.
Calcium Magnesium TabNutricorp International
Calcium Magnesium Tablets Nu LifeNu Life Nutrition Ltd.
Calcium Magnesium With Potassium TabNutrition For Life International
Calcium PlusLaboratoire Riva Inc
Calcium With Magnesium and Vitamin DGeneral Nutrition Canada Inc.
Calcium With Mg Zn Mn Cu CR Si and Vit. C & DJamieson Laboratories Ltd
Calcium-magnesium Cap 1:1 W Vitamin DSisu Inc.
Calcium-magnesium With K & Zn and Vitamin D3Holista Health (Canada) Inc.
Calcium, Magnesium, Zinc and DNutravite Pharmaceuticals Inc.
Calcium/magnesium DrinkNew Vision Nutritionals Company
Calcium/magnesium Supplement TabletsGeneral Nutrition Canada Inc.
Calcium/magnesium/vitamin D - CapsuleHolista Health (Canada) Inc.
CalcorSimone Protective Pharmaceuticals, Inc.
Calma-DWn Pharmaceuticals Ltd.
CalmaxMedia Power, Inc.
CalplusLifestyles Canada Corporation
Carti-aide TabAvant Garde, Les SupplÉments
Chela Calmag-100 Plus Zinc D3Nu Life Nutrition Ltd.
Chela Calmag-300 Plus Zinc D3Nu Life Nutrition Ltd.
Chelated Cal-mag(2:1)with Zn Vit.c and DHealth Wise Nutrition Inc.
Chelated Cal/mag/zn With VitaminsHealth Wise Nutrition Inc.
Chelated Calcium and Magnesium TabAlive Vitamins
Chewable Cal-mag Chocolate FlavourViva Life Science, Inc.
Chewable Calcium & Magnesium 2:1 TabletSwiss Herbal Remedies Ltd.
Chewable Calcium Plus Magnesium and MineralsNature's Sunshine Products Of Canada Ltd.
Chromease TabAnabolic Laboratories Inc.
Complete Multivitamins and Minerals Tablets Timed ReleasePharmetics (2011) Inc
Derma-forcePrairie Naturals
Dol Mite TabSwiss Herbal Remedies Ltd.
Dolomite 1280mgRay Irastorza
E.S.T. ComplexAbundance Marketing Ltd.
Efferlife Multivitamins and MineralsNaturale Science Inc.
Effervescent Vitamin C Powder With Ca and mgThorne Research Canada Ltd.
Enviroflex - TabEnviro Tech International Canada
EscaviteGm Pharmaceuticals, Inc.
Ez-flexMetagenics, Inc.
Fem - F.S. FormulaMetagenics, Inc.
Fem - PmtMetagenics, Inc.
Female AdvantageBody Wise International Llc
FemidausePns Pharma Therapy
Feminex 300 TabSantÉ Naturelle (Ag) LtÉe
Femitab TabLe Groupe Prodeal Ltee
Flex CapsulesFoodscience Laboratories, Division Of Foodscience Corporation
Folcaps Care OneMidlothian Laboratories
Folet OnePronova Corporation
Formula 9 TabPure Life International Prods Inc.
Formula BPNutrivention Nutritional Products
Formula CmNutrivention Nutritional Products
Formula CnBalance Plus, Inc.
Formula CwBody Wise International Llc
Formula Cw-capletBody Wise International Llc
Formula Est'ro Tab SupportBalance Plus, Inc.
Formula Fe-vitamin and Mineral TabMetagenics, Inc.
Formula Fm Vitamins & Minerals TabMetagenics, Inc.
Formula InfBalance Plus, Inc.
Formula JsNutrivention Nutritional Products
Formula O-care Vitamin and Mineral SupplementFor Mor International Inc.
Formula OsgSeroyal International Inc.
Formula R TabMetagenics, Inc.
Formule 3000Le Naturiste J.M.B. Inc.
Fortifi-plusClinique Lafontaine Inc, Division Les Importations Ortho
Fusion Activator Formula TabL & S Research Corporation
Fusion PM Formula TabL & S Research Corporation
G.A.S. ComplexAbundance Marketing Ltd.
Glyco-aide TabAvant Garde, Les SupplÉments
Good Night/pm Formula TabNikken Usa, Incorporated
Hvp Chelated Cal/mag With Zinc and Vitamins C and DDarwen Holdings Ltd.
Hyperlyte (multi-electrolyte Concentrate)B. Braun Medical Inc
Hypo Vites TabPharmetics (2011) Inc
Isotonix Advanced B-complex Vitamins With Potassium and MagnesiumMarket America, Inc.
Isotonix Calcium Plus FormulaMarket America, Inc.
Isotonix Vitamin B-folic Acid-mineral SuppleMarket America, Inc.
Kanga Sport Vitamins B & C Plus MineralsLacombe Drugs (1992) Ltd
Kanga-kid Multi-vitamin & MineralLacombe Drugs (1992) Ltd
Kanga-V Multivitamins & MineralsLacombe Drugs (1992) Ltd
Kmg PlusSeroyal International Inc.
LiquicalLand Art Inc.
Liquid Cal-magSeroyal International Inc.
Liquid Cal/mag Plus DGahler Enterprises Ltd.
Liquid Calcium and Magnesium With Vit.dRheingold Food International Ltd.
LypholytePharmaceutical Partners Of Canada Inc
Lypholyte Multi-electrolyte Conc InjLyphomed, Division Of Fujisawa Canada Inc.
Mag/cal 1:1 Capsules W Vitamin DRheingold Food International Ltd.
MagnacalHolista Health (Canada) Inc.
Magnesium 50mg With Vitamin B6 TabJamieson Laboratories Ltd
Magnesium and ZincHealth Thru Herbs Inc.
Magnogene Comprimes EnrobesPhyto Sante ltÉe
MaxfePronova Corporation
Menocal TabLes Aliments Nutri Source Inc.
Meth-X Vitamin and Mineral SupplementDymatize Enterprises Inc.
MgkHorizon SantÉ International Inc.
Mid-life Magnacal 2Holista Health (Canada) Inc.
Min-tran TabStandard Process Inc.
Mnps Formula SupplementGarden State Nutritionals
Multi Vitamin - MineralEnrich International
Multi Vitamin & MineralsWn Pharmaceuticals Ltd.
Multi Vitamin-mineral FormulaVita Health Products Inc
Multi Vitamins & MineralsWn Pharmaceuticals Ltd.
Multi-min Electro C Pow Plus B2Quest Vitamins A Div Of Purity Life Health Products
Multi-vitamins With MineralsWn Pharmaceuticals Ltd.
Multimineral ChelatesW.R. Enterprises Inc.
Nata KompleteWh Nutritionals, Llc
Natura Magnesium Plus Vitamin CNaka Sales Ltd.
Neo-vites & Minerals TabNeolab Inc
Normosol M With Dextrose 5%Hospira Healthcare Corporation
Normosol-M and DextroseHospira, Inc.
Nutravite Calcium Magnesium and Zinc CapsNutravite Pharmaceuticals Inc.
Nutri-chem Cal MagNutri Chem Pharmacy Ltd
Nutri-chem Calcium Magnesium With D and ZincNutri Chem Pharmacy Ltd
Nutrilite Double XNutrilite, A Division Of Access Business Group, Llc
NutrilyteAmerican Regent, Inc.
O-cal Fa MultivitaminPharmics, Inc.
O-cal Prenatal VitaminPharmics, Inc.
One A Day Advance AdultsBayer Inc Consumer Care
One A Day Advance Adults 50+Bayer Inc Consumer Care
One A Day TabCountry Health Laboratories Ltd.
Osteo FormulaGeneral Nutrition Canada Inc.
Osteo-lifeViva Pharmaceutical Inc.
Osteo-plusRolmex International Inc.
OsteoligoClinique Lafontaine Inc, Division Les Importations Ortho
P.R.O. ComplexAbundance Marketing Ltd.
PhytopureLaboratoire Lalco Inc.
Plasma-lyte 56 5% Dextrose InjBaxter Corporation
Pnv-dhaAcella Pharmaceuticals, LLC
Port A Mins Super Cal-mag 300/150 With Vitamin D3Great Earth Companies, Inc.
Port A Mins Super Cal-mag 600/300Great Earth Companies, Inc.
Pour Ma SantéProdemdis Enr.
Powertech Vitamin and Mineral SupplementDymatize Enterprises Inc.
PregvitDuchesnay Inc
Pregvit Folic 4Duchesnay Inc
Pregvit Folic 5Duchesnay Inc
PremelLe Naturiste J.M.B. Inc.
Prevencal 600 + D Et MagnesiumLaboratoire Lalco Inc.
Q-10 PlusThorne Research Inc.
Q.T. Vitamin and Mineral Drink MixGarden State Nutritionals
Reaphirm Plant Source DHAEverett Laboratories, Inc.
ReebokClearly Canadian Beverage Corporation
Rolaids Extra Strength Multi-symptom TabletsSanofi Consumer Health Inc Sanofi Sante Grand Public Inc
Rolaids Extra Strength TabWarner Lambert Canada Inc.
Spectra 301 Vitamin and Mineral SuppNf Formulas Inc.
Spectrum 2 CapNf Formulas Inc.
Strovite Forte CapletEverett Laboratories, Inc.
Super C-M-KCreative Nutrition Canada Corp.
Super Cal Mag PlusShaklee Canada Inc
Super Charged EnergySimone Protective Pharmaceuticals, Inc.
Super Daily No 2W.R. Enterprises Inc.
Super-cellBody Wise International Llc
Supplement De Vitamines Et MinerauxLand Art Inc.
Supplements De Vitamines Et MinerauxLand Art Inc.
Swical D-M - TabLes Laboratoires Swisse Inc.
Swical-multiLes Laboratoires Swisse Inc.
T-PA CapSeroyal International Inc.
Tri-buffered Asa TabZee Medical Inc
Tri-mins - CapAlbion Laboratories Inc.
Usana Multimineral TabletsUsana Health Sciences Inc.
Usana Multimineral Tablets - TabUsana Health Sciences Inc.
Vimeral TabIcn Canada Ltd.
Vit C W Calc-mag and Potass PowderNf Formulas Inc.
Vita - Gl CapsulesAnton Hubner Gmbh & Co.
Vitafol Ob CapletEverett Laboratories, Inc.
Vitafol OneEverett Laboratories, Inc.
Vitafol PlusEverett Laboratories, Inc.
Vitalife - CapsuleHolista Health (Canada) Inc.
Vitality Brand Calcium Plus TabGolden Neo Life Diamite International, Limited
Vtb Vitamin and Mineral SupplementGarden State Nutritionals
Women's FormulaPro Ma Systems
Women's Support TabletsGeneral Nutrition Canada Inc.
Z-force Vitamin and Mineral SupplementDymatize Enterprises Inc.
Z-mass PM Vitamin and Mineral SupplementCytodyne Technologies Inc.
Salts
Name/CASStructureProperties
Magnesium acetate
ThumbNot applicableDBSALT001426
Categories
UNIII38ZP9992A
CAS number7439-95-4
WeightAverage: 24.305
Monoisotopic: 23.985041898
Chemical FormulaMg
InChI KeyInChIKey=JLVVSXFLKOJNIY-UHFFFAOYSA-N
InChI
InChI=1S/Mg/q+2
IUPAC Name
magnesium(2+) ion
SMILES
[Mg++]
Taxonomy
DescriptionThis compound belongs to the class of inorganic compounds known as homogeneous alkaline earth metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a alkaline earth metal atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous alkaline earth metal compounds
Sub ClassNot Available
Direct ParentHomogeneous alkaline earth metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous alkaline earth metal
  • Acyclic compound
Molecular FrameworkAcyclic compounds
External Descriptors
Pharmacology
IndicationNot Available
PharmacodynamicsNot Available
Mechanism of actionNot Available
Related Articles
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityNot Available
Affected organismsNot Available
Pathways
PathwayCategorySMPDB ID
Phospholipid BiosynthesisMetabolicSMP00025
Pentose Phosphate PathwayMetabolicSMP00031
Riboflavin MetabolismMetabolicSMP00070
Arachidonic Acid MetabolismMetabolicSMP00075
Rosuvastatin Action PathwayDrug actionSMP00092
Meloxicam Action PathwayDrug actionSMP00106
Mefenamic Acid Action PathwayDrug actionSMP00109
Fluvastatin Action PathwayDrug actionSMP00119
Betaine MetabolismMetabolicSMP00123
Cystathionine Beta-Synthase DeficiencyDiseaseSMP00177
GalactosemiaDiseaseSMP00182
Sialuria or French Type SialuriaDiseaseSMP00217
Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)DiseaseSMP00235
Acebutolol Action PathwayDrug actionSMP00296
Atenolol Action PathwayDrug actionSMP00298
Nadolol Action PathwayDrug actionSMP00303
Oxprenolol Action PathwayDrug actionSMP00304
Pindolol Action PathwayDrug actionSMP00306
Corticotropin Activation of Cortisol ProductionSignalingSMP00310
Excitatory Neural Signalling Through 5-HTR 7 and Serotonin SignalingSMP00311
Intracellular Signalling Through Adenosine Receptor A2a and AdenosineSignalingSMP00320
Gaucher DiseaseDiseaseSMP00349
Fc Epsilon Receptor I Signaling in Mast CellsSignalingSMP00358
Gout or Kelley-Seegmiller SyndromeDiseaseSMP00365
Carvedilol Action PathwayDrug actionSMP00367
Tyrosinemia Type 2 (or Richner-Hanhart syndrome)DiseaseSMP00369
Tyrosinemia Type 3 (TYRO3)DiseaseSMP00370
Isradipine Action PathwayDrug actionSMP00378
CHILD SyndromeDiseaseSMP00387
Azathioprine Action PathwayDrug actionSMP00427
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.8382
Blood Brain Barrier+0.9708
Caco-2 permeable+0.7056
P-glycoprotein substrateNon-substrate0.8831
P-glycoprotein inhibitor INon-inhibitor0.9869
P-glycoprotein inhibitor IINon-inhibitor0.9855
Renal organic cation transporterNon-inhibitor0.9176
CYP450 2C9 substrateNon-substrate0.8465
CYP450 2D6 substrateNon-substrate0.823
CYP450 3A4 substrateNon-substrate0.8094
CYP450 1A2 substrateNon-inhibitor0.8824
CYP450 2C9 inhibitorNon-inhibitor0.9221
CYP450 2D6 inhibitorNon-inhibitor0.9555
CYP450 2C19 inhibitorNon-inhibitor0.9469
CYP450 3A4 inhibitorNon-inhibitor0.9846
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9015
Ames testNon AMES toxic0.9663
CarcinogenicityCarcinogens 0.6381
BiodegradationReady biodegradable0.9031
Rat acute toxicity2.0881 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9462
hERG inhibition (predictor II)Non-inhibitor0.9716
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Tabletoral250 mg
Capsuleoral
Waferoral
Tabletoral150 mg
Tabletoral50 mg
Tablet (extended-release)oral
Tablet (effervescent)oral
Tablet, chewableoral
Capsuleoral80 mg
Liquidintravenous
Powderoral
Liquidoral
Capsuleoral165 mg
Tabletoral100 mg
Capsuleoral72.5 mg
Capsuleoral125 mg
Capsuleoral250 mg
Capsuleoral100 mg
Capsuleoral90 mg
Capsuleoral150 mg
Tabletoral300 mg
Capsuleoral70 mg
Liquidoral114 mg
Powderoral240 mg
Tabletoral252 mg
Tabletoral70 mg
Solutionoral118.6 mg
Tabletoral200 mg
Liquidoral23.92 mg
Powderoral119.6 mg
Liquidoral1 g
Capsuleoral20 mg
Powder (effervescent)oral
Tabletoral36 mg
Plastertopical3 g/100g
Solutionintravenous
Injection, solutionintravenous
Injection, solution, concentrateintravenous
Liquidoral10.24 mg
Tabletoral188 mg
Tabletoral375 mg
Tablet (enteric-coated)oral64 mg
Tablet, coatedoral
Powder for solutionoral
Tabletoral
Capsule, gelatin coatedoral
Capsule, liquid filledoral
PricesNot Available
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point651 °CPhysProp
boiling point1100 °CPhysProp
Predicted Properties
PropertyValueSource
logP-0.57ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
References
Synthesis Reference

David S. Thompson, John S. Prestley, Jr., Thomas E. Webb, “Aluminum-magnesium alloys sheet exhibiting improved properties for forming and method aspects of producing such sheet.” U.S. Patent US4151013, issued 0000.

US4151013
General ReferencesNot Available
External Links
ATC CodesNot Available
AHFS Codes
  • 28:08.04.24
  • 28:12.92
  • 40:12.00
  • 40:34.00*
  • 56:04.00
  • 56:12.00
  • 84:24.00
  • 84:92.00
  • 88:29.00*
  • 92:02.00*
PDB EntriesNot Available
FDA labelNot Available
MSDSDownload (73.4 KB)
Interactions
Drug InteractionsNot Available
Food InteractionsNot Available

Targets

Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Steroid hormone binding
Specific Function:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Gene Name:
ATP1A1
Uniprot ID:
P05023
Molecular Weight:
112895.01 Da
References
  1. Buchachenko AL, Kuznetsov DA, Berdinskii VL: [New mechanisms of biological effects of electromagnetic fields]. Biofizika. 2006 May-Jun;51(3):545-52. [PubMed:16808357 ]
  2. Sirijovski N, Olsson U, Lundqvist J, Al-Karadaghi S, Willows RD, Hansson M: ATPase activity associated with the magnesium chelatase H-subunit of the chlorophyll biosynthetic pathway is an artefact. Biochem J. 2006 Dec 15;400(3):477-84. [PubMed:16928192 ]
  3. Balasubramaniyan V, Nalini N: Leptin alters brain adenosine triphosphatase activity in ethanol-mediated neurotoxicity in mice. Singapore Med J. 2006 Oct;47(10):864-8. [PubMed:16990961 ]
  4. Nogovitsina OR, Levitina EV: Neurological aspects of the clinical features, pathophysiology, and corrections of impairments in attention deficit hyperactivity disorder. Neurosci Behav Physiol. 2007 Mar;37(3):199-202. [PubMed:17294093 ]
Comments
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Drug created on July 06, 2007 14:30 / Updated on August 17, 2016 12:23