Certoparin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Certoparin is a low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.

Generic Name
Certoparin
DrugBank Accession Number
DB09261
Background

Certoparin is part of the heparins of low molecular weight that presents high activity against the coagulation factor Xa. It is normally used to prevent deep venous thrombosis.

Type
Small Molecule
Groups
Approved, Investigational
Synonyms
Not Available

Pharmacology

Indication

Used in the prevention and treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism) and in the treatment of myocardial infarction.

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Prevention ofDeep vein thrombosis•••••••••••••••••••• •••••••••••••
Prevention ofDeep vein thrombosis•••••••••••••••• •••••••••••••
Prevention ofThrombotic events caused by general surgery••••••••••••••••••••••••••••••••••
Prevention ofThrombotic events caused by general surgery••••••••••••••••••••••••••••••••••
Prevention ofThrombotic events caused by mobility decreased•••••••••••••••• •••••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcebutololThe risk or severity of hyperkalemia can be increased when Acebutolol is combined with Certoparin.
AceclofenacThe risk or severity of hyperkalemia can be increased when Aceclofenac is combined with Certoparin.
AcemetacinThe risk or severity of hyperkalemia can be increased when Certoparin is combined with Acemetacin.
Acetylsalicylic acidThe risk or severity of hyperkalemia can be increased when Acetylsalicylic acid is combined with Certoparin.
AlclofenacThe risk or severity of hyperkalemia can be increased when Certoparin is combined with Alclofenac.
Food Interactions
  • Avoid herbs and supplements with anticoagulant/antiplatelet activity. Examples include garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

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International/Other Brands
Embolex / Sandoparin

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
V72OT3K19I
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347910425
RxNav
152610
Wikipedia
Certoparin_sodium

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Unknown StatusTreatmentHeparin Induced Thrombocytopenia (HIT)1
3CompletedPreventionRenal Dialysis1
3CompletedPreventionSystemic Embolism1
3CompletedPreventionThromboembolism1
3CompletedTreatmentPersistent Nonvalvular Atrial Fibrillation1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionParenteral3000 IE
Injection, solutionParenteral8000 IE
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at October 26, 2015 17:10 / Updated at May 07, 2021 21:06