You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on DrugBank.
Identification
NameAcetylsalicylic acid
Accession NumberDB00945  (APRD00264, EXPT00475)
TypeSmall Molecule
GroupsApproved, Vet Approved
Description

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Acetylsalicylic acid also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Structure
Thumb
Synonyms
2-(ACETYLOXY)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoic acid
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acide 2-(acetyloxy)benzoique
Acide acétylsalicylique
ácido acetilsalicílico
Acidum acetylsalicylicum
ASA
Aspirin
Azetylsalizylsaeure
Azetylsalizylsäure
Easprin
o-acetoxybenzoic acid
O-acetylsalicylic acid
o-carboxyphenyl acetate
Polopiryna
Salicylic acid acetate
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Asa Ect 600mgtablet (enteric-coated)600 mgBionatal Drug Co1977-12-311999-07-14Canada
Asa Tab 325mgtablet325 mgEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada
Durlazacapsule, extended release162.5 mg/1oralNew Haven Pharmaceuticals, Inc.2015-09-162016-04-05Us
Headache Tab 300mgtablet300 mgLaboratoire Romilo1979-12-311999-08-18Canada
Generic Prescription ProductsNot Available
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
7 Select Adult Chewable Aspirintablet, chewable81 mg/1oral7 Eleven2014-08-052016-04-05Us
7 Select Aspirintablet325 mg/1oral7 Eleven2014-08-052016-04-05Us
A.S.A.tablet325 mgoralD.C. Labs Limited2001-05-282005-07-19Canada
A.S.A.tablet500 mgoralD.C. Labs Limited2001-12-222005-07-19Canada
A.S.A. (acetylsalicylic Acid) Tab 325mg USPtablet325 mgoralAccurex Health Care Manufacturing Inc.1996-12-312003-01-28Canada
A.S.A. 325 Mg Tablettablet325 mgoralJamp Pharma Corporation2003-10-16Not applicableCanada
A.S.A. 80mg Acetylsalicylic Acid Tabletstablet80 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1995-12-312002-07-31Canada
A.S.A. Enteric Coated Tab 325mgtablet (enteric-coated)325 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1987-12-312004-07-26Canada
A.S.A. Enteric Coated Tab 650mgtablet (enteric-coated)650 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1987-12-312004-07-26Canada
A.S.A. Tablets 5gr BPtablet325 mgoralWestcan Pharmaceuticals Ltd.1997-09-081998-04-07Canada
Acetylsalicylic Acid 325mg Tablets USPtablet325 mgoralPharmetics (2011) Inc2004-11-12Not applicableCanada
Acetylsalicylic Acid 325mg Tablets USPtablet325 mgoralProdemdis Enr.2002-08-102010-07-15Canada
Acetylsalicylic Acid 80 Mg Chewable Tabletstablet80 mgoralJamp Pharma Corporation2006-10-26Not applicableCanada
Acetylsalicylic Acid A.S.A. Tablets 325mgtablet325 mgoralWestcan Pharmaceuticals Ltd.1996-02-072002-07-31Canada
Acetylsalicylic Acid Extra Strength 500mg Tablets USPtablet500 mgoralPharmetics (2011) Inc2004-11-19Not applicableCanada
Acetylsalicylic Acid Extra Strength Stomach Protection 500mg Capletstablet500 mgoralPharmetics (2011) IncNot applicableNot applicableCanada
Acetylsalicylic Acid Stomach Protection 325mg Tabletstablet325 mgoralPharmetics (2011) IncNot applicableNot applicableCanada
Acetylsalicylic Acid Tab 300mgtablet300 mgoralPharmetics (2011) Inc1962-12-312006-07-27Canada
Acetylsalicylic Acid Tab 325mgtablet325 mgoralPharmel Inc1987-12-31Not applicableCanada
Acetylsalicylic Acid Tab 325mg BPtablet325 mgoralWes Pak Products Ltd.1995-12-312000-08-04Canada
Adult Low Dose Aspirintablet, delayed release81 mg/1oralLiberty Pharmaceuticals, Inc.2007-01-122016-04-23Us
Adult Low Dose Aspirintablet, delayed release81 mg/1oralAidarex Pharmaceuticals LLC2007-01-122016-04-05Us
Adult Low Dose Aspirintablet, delayed release81 mg/1oralPharbest Pharmaceuticals, Inc.2007-01-122016-04-05Us
Adult Low Dose Aspirintablet, delayed release81 mg/1oralREMEDYREPACK INC.2015-06-152016-04-05Us
Adult Low Dose Aspirin Enteric Safety Coatedtablet, delayed release81 mg/1oralZandi LLC2011-01-182016-04-05Us
Adult Low Dose Enteric Coated Aspirintablet, coated81 mg/1oralPreferred Pharmaceuticals Inc.2015-10-062016-04-05Us
Adult Low Dose Enteric Coated Aspirintablet, coated81 mg/1oralGeri Care Pharmaceutical Corp2000-07-012016-04-05Us
Adult Low Dose Enteric Coated Aspirintablet, coated81 mg/1oralTYA Pharmaceuticals2000-07-012016-04-05Us
Adult Low Dose Enteric Coated Aspirintablet, coated81 mg/1oralREMEDYREPACK INC.2015-12-302016-04-05Us
Adult Low Strength Aspirintablet, coated81 mg/1oralSafeway2004-01-142018-05-27Us
Adult Low Strength Aspirintablet, coated81 mg/1oralDolgencorp, LLC2004-01-142018-05-27Us
Adult Low Strength Aspirintablet, coated81 mg/1oralArmy and Air Force Exchange Service2004-01-142016-02-19Us
Adult Low Strength Aspirintablet, coated81 mg/1oralBedrock Brands, Llc2004-01-142018-05-27Us
Adult Low Strength Aspirintablet, coated81 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2004-01-142015-11-20Us
Adult Low Strength Aspirintablet, coated81 mg/1oralSUPERVALU INC.2004-01-142015-10-15Us
Adults Low Strength Aspirintablet81 mg/1oralGenvion Corporation2015-06-012016-04-05Us
Apo Asa Tab 325mgtablet325 mgoralApotex Inc1989-12-31Not applicableCanada
Asatablet (chewable)80 mgoralSanis Health IncNot applicableNot applicableCanada
Asatablet (delayed-release)81 mgoralPharmascience Inc2015-05-06Not applicableCanada
Asa 325 Mg Tablets Regular Strengthtablet325 mgoralTanta Pharmaceuticals IncNot applicableNot applicableCanada
Asa 325mgtablet325 mgoralVita Health Products Inc1981-12-31Not applicableCanada
Asa 500 Mg Tablets Extra Strengthtablet500 mgoralTanta Pharmaceuticals Inc2013-05-02Not applicableCanada
Asa 80tablet (chewable)80 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Asa 80 mgtablet80 mgoralJamieson Laboratories LtdNot applicableNot applicableCanada
Asa 80mgtablet80 mgoralVita Health Products Inc1996-10-112004-07-26Canada
Asa 81 mgtablet (delayed-release)81 mgoralPharmascience Inc2001-11-30Not applicableCanada
Asa 81 mgtablet (delayed-release)81 mgoralLaboratoires Trianon IncNot applicableNot applicableCanada
Asa 81 mgtablet (delayed-release)81 mgoralVita Health Products Inc2012-01-12Not applicableCanada
Asa 975 Tabtablet (enteric-coated)975 mgoralPro Doc Limitee1983-12-311999-08-12Canada
Asa Acetylsalicylic Acidtablet325 mgoralGfr Pharma Ltd.2004-07-062011-07-15Canada
Asa Acetylsalicylic Acidtablet325 mgoralLil' Drug Store Products Inc2013-11-12Not applicableCanada
Asa Chewable Tabletstablet80 mgoralTherapharma Inc.Not applicableNot applicableCanada
Asa Daily Low Dosetablet (chewable)81 mgoralPharmascience IncNot applicableNot applicableCanada
Asa Daily Low Dosetablet (enteric-coated)81 mgoralPharmascience Inc2001-04-03Not applicableCanada
Asa ECtablet (delayed-release)80 mgoralSanis Health Inc2014-07-16Not applicableCanada
Asa ECtablet (delayed-release)81 mgoralSanis Health Inc2014-07-25Not applicableCanada
Asa EC 80tablet (delayed-release)80 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Asa Ect 325mgtablet (enteric-coated)325 mgoralShoppers Drug Mart Inc.1979-12-311998-08-14Canada
Asa Ect 650mgtablet (enteric-coated)650 mgoralD.C. Labs Limited1970-12-312005-07-19Canada
Asa Ect 650mgtablet (enteric-coated)650 mgoralShoppers Drug Mart Inc.1978-12-311998-08-14Canada
Asa Extra Strength Caplet 500mgtablet500 mgoralWestcan Pharmaceuticals Ltd.1996-10-112004-07-26Canada
Asa Extra Strength Tab 500mgtablet500 mgoralVita Health Products Inc1996-10-112007-07-30Canada
Asa Suppositories 150mgsuppository150 mgrectalPharmascience Inc1990-12-31Not applicableCanada
Asa Suppositories 650mgsuppository650 mgrectalPharmascience Inc1990-12-31Not applicableCanada
Asa Tab 325mgtablet325 mgoralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1957-12-312002-07-31Canada
Asa Tab 325mgtablet325 mgoralNovopharm Limited1978-12-312015-10-26Canada
Asa Tab 325mgtablet325 mgoralDrug Trading Company Ltd.1951-12-311996-09-17Canada
Asa Tab 325mgtablet325 mgoralShoppers Drug Mart Inc.1984-12-311997-08-15Canada
Asa Tab 325mg Enteric Coatedtablet (enteric-coated)325 mgoralD.C. Labs Limited1969-12-312005-07-19Canada
Asa Tablets USP 325 mgtablet325 mgoralPendopharm Division Of De Pharmascience Inc1971-12-312014-09-19Canada
Asa-325 Comprimes Retardtablet (enteric-coated)325 mgoralPro Doc Limitee1959-12-311999-08-12Canada
Asa-650 Comprimes Retardtablet (enteric-coated)650 mgoralPro Doc Limitee1978-12-311999-08-12Canada
Asadol 325mgtablet (enteric-coated)325 mgoralPendopharm Division Of De Pharmascience Inc1993-12-312011-09-30Canada
Asadol 650mgtablet (enteric-coated)650 mgoralPendopharm Division Of De Pharmascience Inc1993-12-312011-09-30Canada
Asaphentablet (chewable)80 mgoralPharmascience Inc1995-12-31Not applicableCanada
Asaphen E.C.tablet (delayed-release)80 mgoralPharmascience Inc1998-12-03Not applicableCanada
Asaphen ECtablet (delayed-release)162 mgoralPharmascience Inc2003-09-02Not applicableCanada
Asaphen Plus 325tablet325 mgoralPharmascience IncNot applicableNot applicableCanada
Asatab 80 Mg Chewable Tabletstablet (chewable)80 mgoralOdan Laboratories Ltd2006-05-23Not applicableCanada
Asatab EC 325mgtablet (delayed-release)325 mgoralOdan Laboratories Ltd2010-06-11Not applicableCanada
Asatab EC 650mgtablet (delayed-release)650 mgoralOdan Laboratories Ltd2010-06-11Not applicableCanada
Ascriptin Maximum Strength Buffered Aspirintablet, film coated500 mg/1oralNovartis Consumer Health, Inc.2009-12-312016-04-23Us
Ascriptin Regular Strength Buffered Aspirintablet, film coated325 mg/1oralNovartis Consumer Health, Inc.2009-09-242016-04-23Us
Aspergum 325 Mg (cherry)gum325 mgoralHeritage Brands, A Subsidiary Of Insight Pharmaceuticals Llc1985-01-012015-06-24Canada
Aspergum Orange 325 mggum325 mgoralHeritage Brands, A Subsidiary Of Insight Pharmaceuticals Llc1985-01-012015-06-24Canada
Aspi-cortablet, coated81 mg/1oralL.N.K. International, Inc.2015-02-032016-04-05Us
Aspir Lowtablet81 mg/1oralUnit Dose Services2011-05-242016-04-05Us
Aspir Lowtablet81 mg/1oralCardinal Health2011-05-242016-04-05Us
Aspir Lowtablet81 mg/1oralMajor Pharmaceuticals2011-05-242016-04-05Us
Aspir Lowtablet81 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-05-242016-04-01Us
Aspir Lowtablet81 mg/1oralUnit Dose Services2011-05-242016-04-05Us
Aspirintablet, coated81 mg/1oralCVS Pharmacy2015-07-312016-04-05Us
Aspirintablet, coated81 mg/1oralRUGBY LABORATORIES, INC2014-01-142016-04-23Us
Aspirintablet, coated81 mg/1oralWALGREEN CO.2004-01-142018-05-27Us
Aspirintablet, film coated325 mg/1oralSina Health Inc2011-07-252016-04-05Us
Aspirintablet, coated81 mg/1oralBest Choice (Valu Merchandisers Company)2014-06-302016-04-05Us
Aspirintablet, film coated325 mg/1oralContract Pharmacy Services Pa2010-08-102016-04-05Us
Aspirinsuppository600 mg/1rectalPaddock Laboratories, LLC1990-09-012016-04-23Us
Aspirintablet, coated81 mg/1oralL&R Distributors, Inc.2008-02-122016-04-05Us
Aspirintablet, coated81 mg/1oralRite Aid2004-04-142017-03-18Us
Aspirintablet, chewable81 mg/1oralMc Kesson Contract Packaging2011-11-172016-04-05Us
Aspirintablet325 mg/1oralAdvance Pharmaceutical Inc.2002-01-092016-04-05Us
Aspirintablet81 mg/1oralThe Kroger Co.2014-06-302016-04-05Us
Aspirintablet325 mg/1oralWinder Laboratories, LLC2011-08-252016-03-16Us
Aspirintablet81 mg/1oralLake Erie Medical DBA Quality Care Products LLC2009-11-032016-04-05Us
Aspirintablet325 mg/1oralHannaford Brothers Company1995-06-272016-04-05Us
Aspirintablet, chewable81 mg/1oralCardinal Health1990-09-122016-05-31Us
Aspirintablet, coated81 mg/1oralCispharma, Inc2011-02-142016-04-05Us
Aspirintablet, chewable81 mg/1oralMeijer Distribution Inc1996-11-262016-04-05Us
Aspirintablet325 mg/1oralL.N.K. International, Inc.1996-02-102016-04-05Us
Aspirintablet325 mg/1oralPublix Super Markets Inc1988-09-152016-04-05Us
Aspirintablet, coated81 mg/1oralDolgencorp, LLC2004-04-142018-06-03Us
Aspirintablet, delayed release81 mg/1oralAAA Pharmaceutical, Inc.2012-12-152016-04-05Us
Aspirintablet325 mg/1oralGreenbrier International, Inc.1993-08-042016-04-05Us
Aspirintablet, film coated325 mg/1oralChain Drug Consortium1996-02-102016-04-05Us
Aspirintablet81 mg/1oralbryant ranch prepack2008-04-282016-04-05Us
Aspirinsuppository300 mg/1rectalPaddock Laboratories, LLC1990-09-012016-04-23Us
Aspirintablet81 mg/1oralPreferred Pharmaceuticals, Inc.2013-06-062016-04-05Us
Aspirintablet, chewable81 mg/1oralAdvance Pharmaceutical Inc.1988-04-152016-04-05Us
Aspirintablet81 mg/1oralThe Kroger Co.2011-08-302016-04-05Us
Aspirintablet325 mg/1oralHART Health1986-06-042016-04-05Us
Aspirintablet, chewable81 mg/1oralH E B1998-02-182016-04-05Us
Aspirintablet325 mg/1oralPhysicians Total Care, Inc.1995-02-272016-04-05Us
Aspirintablet, delayed release81 mg/1oralHy Vee Inc1997-06-252016-04-05Us
Aspirintablet, coated81 mg/1oralCardinal Health2012-11-132016-04-05Us
Aspirintablet, chewable81 mg/1oralPublix Super Markets Inc1998-08-242016-04-05Us
Aspirintablet, chewable81 mg/1oralAAA Pharmaceutical, Inc.2012-12-152016-04-05Us
Aspirintablet325 mg/1oralUNITED EXCHANGE CORP.2016-03-022016-04-05Us
Aspirintablet, delayed release325 mg/1oralbryant ranch prepack2012-05-082016-04-05Us
Aspirintablet325 mg/1oralWin Co Foods, Llc1996-02-102016-04-05Us
Aspirintablet81 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-08-052016-04-23Us
Aspirintablet325 g/1oralApotheca, Inc1983-04-152016-04-05Us
Aspirintablet81 mg/1oralVelocity Pharma2011-04-012016-04-05Us
Aspirintablet, film coated325 mg/1oralGreenbrier International, Inc.1996-02-102016-04-05Us
Aspirintablet325 mg/1oralL.N.K. International, Inc.1993-08-042016-04-05Us
Aspirintablet325 mg/1oralH E B2006-02-102016-04-05Us
Aspirintablet325 mg/1oralGenuine First Aid LLC2010-04-232016-04-05Us
Aspirintablet, chewable81 mg/1oralHy Vee Inc1995-11-092016-04-05Us
Aspirintablet, coated81 mg/1oralCardinal Health2012-11-132016-04-05Us
Aspirintablet, chewable81 mg/1oralWestern Family Foods Inc1993-03-302016-04-05Us
Aspirintablet, chewable81 mg/1oralPublix Super Markets Inc1999-07-022016-04-05Us
Aspirintablet, delayed release325 mg/1oralAAA Pharmaceutical, Inc.2012-12-152016-04-05Us
Aspirintablet, chewable81 mg/1oralCVS Pharmacy1992-08-252016-04-05Us
Aspirintablet325 mg/1oralAtlantic Biologicals Corps1993-08-042016-04-05Us
Aspirintablet325 mg/1oralSt Mary's Medical Park Pharmacy1993-08-042016-04-05Us
Aspirintablet325 mg/1oralUnited Exchange Corporation1993-08-042016-04-01Us
Aspirintablet, film coated325 mg/1oralHIMPRIT PHARMACHEM PVT LTD2010-03-012016-04-05Us
Aspirintablet, delayed release325 mg/1oralTIME CAP LABORATORIES INC.2012-05-082016-04-05Us
Aspirintablet, delayed release81 mg/1oralMeijer Distribution Inc1993-08-262016-04-05Us
Aspirintablet, coated81 mg/1oralNew World Imports, Inc2011-01-252016-04-05Us
Aspirintablet325 mg/1oralDolgencorp, LLC1993-08-042016-04-05Us
Aspirintablet, delayed release81 mg/1oralAAA Pharmaceutical, Inc.2012-12-152016-04-05Us
Aspirintablet, film coated325 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1996-02-102016-04-05Us
Aspirintablet, delayed release81 mg/1oralMc Kesson2012-12-152016-04-05Us
Aspirintablet81 mg/1oralSt Marys Medical Park Pharmacy2014-05-222016-04-05Us
Aspirintablet, coated325 ng/1oralLiberty Pharmaceuticals, Inc.2012-04-182016-04-23Us
Aspirintablet, coated81 mg/1oralQUALITY CHOICE (Chain Drug Marketing Association)2014-07-312016-04-05Us
Aspirintablet81 mg/1oralCarilion Materials Management2009-11-032016-04-05Us
Aspirintablet81 mg/1oralMajor Pharmaceuticals2010-07-162016-04-05Us
Aspirintablet, film coated325 mg/1oralL.N.K. International, Inc.2006-02-102016-04-05Us
Aspirintablet, film coated325 mg/1oralSUPERVALU INC.2006-02-102016-04-05Us
Aspirintablet, chewable81 mg/1oralMeijer Distribution Inc1992-08-272016-04-05Us
Aspirintablet, chewable81 mg/1oralNew World Imports, Inc2011-08-312016-04-05Us
Aspirintablet, coated325 mg/1oralArmy and Air Force Exchange Service1996-02-102016-04-05Us
Aspirintablet, chewable81 mg/1oralHy Vee Inc1997-07-252016-04-05Us
Aspirintablet, coated325 mg/1oralAAA Pharmaceutical, Inc.2012-12-152016-04-05Us
Aspirintablet, delayed release81 mg/1oralMc Kesson2012-12-152016-04-05Us
Aspirintablet, film coated325 mg/1oralChain Drug Marketing Association Inc1996-02-102016-04-05Us
Aspirintablet, coated325 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-09-302016-04-23Us
Aspirintablet81 mg/1oralRugby Laboratories Inc.1998-01-232016-04-23Us
Aspirintablet, delayed release81 mg/1oralSunrise Pharmaceutical Inc2010-01-032016-04-05Us
Aspirintablet, chewable81 mg/1oralMajor Pharmaceuticals2007-12-122016-04-05Us
Aspirintablet, coated81 mg/1oralPreferred Pharmaceuticals, Inc2010-06-282016-04-05Us
Aspirintablet325 mg/1oralAi Ping Pharmaceutical, Inc.2014-01-312016-04-05Us
Aspirintablet, coated325 mg/1oralWal Mart Stores Inc2014-02-032016-04-05Us
Aspirintablet, film coated325 mg/1oralBetter Living Brands, Llc2006-02-102018-07-15Us
Aspirintablet325 mg/1oralSave A Lot Food Stores, Ltd.2006-02-102016-04-05Us
Aspirintablet, coated325 mg/1oralILEX Consumer Products Group, LLC (ST. JOSEPH)2012-03-152016-04-05Us
Aspirintablet, coated325 mg/1oralTIME CAP LABS INC2014-04-022016-04-05Us
Aspirintablet, coated325 mg/1oralGeri Care Pharmaceutical1996-02-102016-04-05Us
Aspirintablet325 mg/1oralSalado Sales, Inc.2006-02-102016-04-05Us
Aspirintablet81 mg/1oralDIRECT RX2014-01-012016-04-05Us
Aspirintablet, extended release81 mg/1oralProficient Rx LP2013-01-102016-04-05Us
Aspirintablet325 mg/1oralAthlete's Needs1993-08-042016-04-01Us
Aspirintablet325 mg/1oralVALUE MERCHANDISERS COMPANY, INC.1993-08-042016-04-05Us
Aspirintablet81 mg/1oralRugby Laboratories Inc.2008-04-282016-04-23Us
Aspirintablet, delayed release81 mg/1oralSunrise Pharmaceutical Inc2005-12-262016-04-05Us
Aspirintablet81 mg/1oralAi Ping Pharmaceutical Inc.2014-01-302016-04-05Us
Aspirintablet, coated325 mg/1oralSafecor Health, LLC2014-09-302016-04-05Us
Aspirintablet81 mg/1oralBedrock Brands, LLC (ST. JOSEPH)2014-05-302016-04-05Us
Aspirintablet, delayed release81 mg/1oralMc Kesson2012-12-152016-04-05Us
Aspirintablet325 mg/1oralRebel Distributors Corp2008-11-072016-04-05Us
Aspirintablet, chewable81 mg/1oralKroger Company1992-10-062016-04-05Us
Aspirintablet81 mg/1oralCardinal Health2014-09-202016-04-05Us
Aspirintablet325 mg/1oralState of Florida DOH Central Pharmacy2014-11-012016-04-05Us
Aspirintablet, extended release81 mg/1oralGemini Pharmaceuticals, Inc. dba Plus Pharmaceuticals2013-01-102016-04-05Us
Aspirintablet, film coated325 mg/1oralMoore Medical LLC2008-12-302016-04-05Us
Aspirintablet, delayed release81 mg/1oralPublix Super Markets Inc2001-03-152016-04-05Us
Aspirintablet, chewable81 mg/1oralCVS Pharmacy1997-02-202016-04-05Us
Aspirintablet325 mg/1oralCVS Pharmacy2015-10-142016-04-05Us
Aspirintablet, coated81 mg/1oralWALGREEN CO.2009-03-182016-04-23Us
Aspirintablet, film coated325 mg/1oralContract Pharmacy Services Pa2010-11-012016-04-05Us
Aspirintablet325 mg/1oralQualitest Pharmaceutical, Inc.2009-11-032016-04-23Us
Aspirintablet325 mg/1oralRugby Laboratories1996-02-102016-04-23Us
Aspirintablet325 mg/1oralKareway Product, Inc.2011-11-232016-04-05Us
Aspirintablet325 mg/1oralAllegiant Health2014-12-182016-04-05Us
Aspirintablet81 mg/1oralAdvance Pharmaceutical Inc.1999-06-122016-04-05Us
Aspirintablet, coated81 mg/1oralAmerisource Bergen (Good Neighbor Pharmacy) 461222014-05-012016-04-05Us
Aspirintablet, delayed release81 mg/1oralMc Kesson2012-12-152016-04-05Us
Aspirintablet325 mg/1oralBetter Living Brands, Llc1996-02-102016-04-05Us
Aspirintablet, delayed release81 mg/1oralH E B2004-08-032016-04-05Us
Aspirintablet325 mg/1oralCardinal Health2014-09-202016-04-05Us
Aspirintablet, coated325 mg/1oralMEIJER, INC.2014-06-302016-04-05Us
Aspirintablet325 mg/1oralCardinal Health2011-06-022016-04-05Us
Aspirintablet81 mg/1oralCardinal Health2011-05-232016-04-05Us
Aspirintablet325 mg/1oralPure Tek Corporation2011-07-072016-04-05Us
Aspirintablet, film coated325 mg/1oralCardinal Health1996-02-102016-04-05Us
Aspirintablet325 mg/1oralCVS Pharmacy2015-08-102016-04-05Us
Aspirintablet81 mg/1oralQualitest Pharmaceutical, Inc.2009-11-032016-04-23Us
Aspirintablet325 mg/1oralRugby Laboratories1993-08-042016-04-23Us
Aspirintablet325 mg/1oralAdvance Pharmaceutical Inc.1990-05-082016-04-05Us
Aspirintablet325 mg/1oralL&R Distributors, Inc.1996-02-102016-04-05Us
Aspirintablet, coated325 mg/1oralThe Kroger Co.2011-01-102016-04-05Us
Aspirintablet325 mg/1oralCardinal Health2014-09-202016-04-05Us
Aspirintablet, coated325 mg/1oralCispharma, Inc2010-11-152016-04-05Us
Aspirintablet, film coated81 mg/1oralMeijer Distribution Inc1992-06-112016-04-05Us
Aspirintablet, chewable81 mg/1oralPhysicians Total Care, Inc.2007-11-012016-04-05Us
Aspirintablet, coated81 mg/1oralCare One (American Sales Company)2014-06-302016-04-05Us
Aspirintablet, chewable81 mg/1oralAAA Pharmaceutical, Inc.2012-12-152016-04-05Us
Aspirintablet, chewable81 mg/1oralPublix Super Markets Inc1999-07-022016-04-05Us
Aspirin - Children's Size - Tabletstablet80 mgoralBayer Inc Consumer Care1995-12-312013-07-19Canada
Aspirin - Children's Size 80mgtablet80 mgoralSterling Winthrop Inc.1950-12-311996-09-10Canada
Aspirin 325 mgtablet325 mg/1oralReliable 1 Laboratories Llc2015-11-012016-04-05Us
Aspirin 325 Mg ECtablet325 mg/1oralReliable 1 Laboratories Llc2015-11-012016-04-05Us
Aspirin 5 Graintablet325 mg/1oralProvision Medical Products2015-03-312016-04-05Us
Aspirin 81 mgtablet, delayed release81 mg/1oralMeijer2014-11-072016-04-05Us
Aspirin 81 mgtablet, delayed release81 mg/1oralChain Drug Marketing Association2014-06-132016-04-05Us
Aspirin 81 mgtablet, chewable81 mg/1oralReliable 1 Laboratories Llc2015-11-012016-04-05Us
Aspirin 81 mgtablet, coated81 mg/1oralDolgencorp, LLC2008-02-122016-04-05Us
Aspirin 81 mgtablet, coated81 mg/1oralH E B2008-02-122016-04-05Us
Aspirin 81 Mg Enteric Coatedtablet81 mg/1oralReliable 1 Laboratories Llc2015-11-012016-04-05Us
Aspirin 81 Mg Low Dosetablet, coated81 mg/1oralMeijer2011-05-012016-04-05Us
Aspirin 81 Mg Nsaid Low Dosetablet, coated81 mg/1oralDolgencorp, LLC2014-07-252016-04-05Us
Aspirin 81mgtablet (enteric-coated)81 mgoralBayer Inc Consumer Care1998-09-02Not applicableCanada
Aspirin 81mg Adult Low Dosetablet, delayed release81 mg/1oralMeijer2011-04-012016-04-05Us
Aspirin 81mg Quick Chewstablet (chewable)81 mgoralBayer Inc Consumer Care2007-05-22Not applicableCanada
Aspirin Adult Low Dosetablet, chewable81 mg/1oralMedicine Shoppe International Inc1997-05-222016-04-05Us
Aspirin Adult Low Dosetablet, coated81 mg/1oralWal Mart Stores Inc2014-07-252016-04-05Us
Aspirin Adult Low Dosetablet, coated81 mg/1oralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.2008-02-122016-04-05Us
Aspirin Adult Low Strengthtablet, film coated81 mg/1oralH E B2005-03-222016-04-05Us
Aspirin Adult Low Strengthtablet, delayed release81 mg/1oralValu Merchandisers Company (Best Choice)2010-07-262016-04-05Us
Aspirin Adult Low Strengthtablet, film coated81 mg/1oralWestern Family Foods Inc2004-05-192016-04-05Us
Aspirin Adult Low Strengthtablet, chewable81 mg/1oralWestern Family Foods Inc2001-09-182016-04-05Us
Aspirin Adult Low Strength Aspirintablet, coated81 mg/1oralAmerisource Bergen (Good Neighbor Pharmacy)2011-03-172016-04-05Us
Aspirin Arthritis Pain Relief 650 mgtablet (delayed-release)650 mgoralBayer Inc Consumer Care1998-08-202009-08-06Canada
Aspirin Chewabletablet81 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2007-12-122016-04-23Us
Aspirin Chewabletablet81 mg/1oralAllegiant Health2014-12-182016-04-05Us
Aspirin Chewable Low Dosetablet, chewable81 mg/1oralWin Co Foods, Llc2014-12-152016-04-05Us
Aspirin Chewable Low Dosetablet81 mg/1oralChain Drug Consortium2001-09-042016-04-05Us
Aspirin Chewable Tabletstablet325 mgoralBayer Inc Consumer Care1994-12-311997-08-01Canada
Aspirin Chewable Tablets - 325mgtablet325 mgoralSterling Winthrop Inc.1994-12-311996-09-10Canada
Aspirin Chewable Tablets - 325mgtablet325 mgoralSterling Winthrop Inc.1994-12-311996-09-10Canada
Aspirin Chewable Tablets 325mgtablet325 mgoralBayer Inc Consumer Care1994-12-311997-08-01Canada
Aspirin Coated Caplets 325 mgtablet (enteric-coated); tablet (extended-release)325 mgoralSterling Winthrop Inc.1993-12-311996-09-10Canada
Aspirin Coated Caplets 500mgtablet (enteric-coated); tablet (extended-release)500 mgoralSterling Winthrop Inc.1993-12-311996-09-10Canada
Aspirin Coated for Delayed Release Extra Strengthtablet (delayed-release)500 mgoralBayer Inc Consumer Care1996-12-31Not applicableCanada
Aspirin Coated for Delayed Release Regular Strengthtablet (delayed-release)325 mgoralBayer Inc Consumer Care1995-12-31Not applicableCanada
Aspirin Delayed Releasetablet, delayed release81 mg/811oralTime Cap Labs, Inc2010-12-232016-04-05Us
Aspirin ECtablet, coated325 mg/1oralPhysicians Total Care, Inc.1993-09-102016-04-05Us
Aspirin ECtablet, coated81 mg/1oralPhysicians Total Care, Inc.2000-11-302016-04-05Us
Aspirin ECtablet, coated81 mg/1oralAphena Pharma Solutions Tennessee, Llc1994-02-052016-04-05Us
Aspirin ECtablet, coated81 mg/1oralRebel Distributors Corp1993-01-012016-04-05Us
Aspirin Enterictablet, coated325 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1992-12-142018-11-02Us
Aspirin Enteric Coatedtablet, coated81 mg/1oralFreds Inc2013-03-152016-04-05Us
Aspirin Enteric Coatedtablet, coated81 mg/1oralPublix Supermarkets, Inc.2013-01-042016-04-05Us
Aspirin Enteric Coatedtablet, coated81 mg/1oralP & L Development, LLC2010-09-012016-12-31Us
Aspirin Enteric Coatedtablet, coated325 mg/1oralTarget Corporation2011-04-052016-04-05Us
Aspirin Enteric Coatedtablet, delayed release81 mg/1oralChain Drug Consortium, LLC2011-03-222016-04-05Us
Aspirin Enteric Coatedtablet, delayed release81 mg/1oralWestern Family Foods Inc2003-07-092016-04-05Us
Aspirin Enteric Coatedtablet, coated81 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2011-05-012016-04-05Us
Aspirin Enteric Coatedtablet325 mg/1oralChain Drug Consortium2014-10-272016-04-05Us
Aspirin Enteric Coatedtablet, delayed release81 mg/1oralWestern Family Foods, Inc.2012-01-042016-04-05Us
Aspirin Enteric Coatedtablet325 mg/1oralAllegiant Health2014-12-182016-04-05Us
Aspirin Enteric Coatedtablet, coated81 mg/1oralChain Drug Marketing Association Inc2011-05-012016-04-05Us
Aspirin Enteric Coatedtablet81 mg/1oralAllegiant Health2014-12-182016-04-05Us
Aspirin Enteric Coated Caplet 325mgtablet (enteric-coated)325 mgoralSterling Winthrop Inc.1993-12-311996-09-10Canada
Aspirin Enteric Coated Low Dosetablet, coated81 mg/1oralWALGREEN CO.2011-05-012016-04-23Us
Aspirin Enteric Coated Low Dosetablet, coated81 mg/1oralWALGREEN CO.2014-07-252016-04-23Us
Aspirin Enteric Coated, Regular Strengthtablet, coated325 mg/1oralWALGREEN CO.1992-12-142016-04-23Us
Aspirin Enteric Safety Coatedtablet, delayed release81 mg/1oralCare One (American Sales Company)2010-07-152016-04-05Us
Aspirin Enteric Safety Coatedtablet, coated81 mg/1oralPublix Supermarkets, Inc.2013-08-152016-04-05Us
Aspirin Enteric Safety Coatedtablet, delayed release81 mg/1oralAvema Pharma Solutions2011-08-112016-04-05Us
Aspirin Enteric Safety Coatedtablet81 mg/1oralCare One (American Sales Company)2014-04-302016-04-05Us
Aspirin Enteric Safety Coatedtablet81 mg/1oralTOP CARE (Topco Associates LLC)2014-06-302016-04-05Us
Aspirin Enteric Safety Coatedtablet81 mg/1oralWestern Family Foods, Inc.2012-01-042016-04-05Us
Aspirin Enteric Safety-coatedtablet81 mg/1oralTarget Corporation2013-03-082016-04-05Us
Aspirin Express Packgranules500 mgoralBayer Inc Consumer Care2008-01-212012-07-12Canada
Aspirin Extra Strengthtablet500 mgoralBayer Inc Consumer Care1995-12-31Not applicableCanada
Aspirin Extra Strengthtablet, coated500 mg/5001oralTime Cap Labs, Inc2013-02-112016-04-05Us
Aspirin Extra Strength 500mg Tab USPtablet500 mgoralSterling Winthrop Inc.1992-12-311996-09-10Canada
Aspirin Extra Strength Plustablet500 mgoralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Extra Strength With Stomach Guardtablet500 mgoralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Extra Strength With Stomach Guardtablet500 mgoralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Granulesgranules500 mgoralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Low Dosetablet, coated81 mg/1oralCostco Wholesale Corporation2011-05-012016-04-05Us
Aspirin Low Dosetablet, delayed release81 mg/1oralWin Co Foods, Llc2014-12-152016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralSafeway2011-05-012016-04-05Us
Aspirin Low Dosetablet, chewable81 mg/1oralL&R Distributors, Inc.1990-09-122016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralBetter Living Brands, Llc2014-07-252016-04-05Us
Aspirin Low Dosetablet, chewable81 mg/1oralKroger Company1997-06-172016-04-05Us
Aspirin Low Dosetablet, chewable81 mg/1oralArmy and Air Force Exchange Service1990-09-122016-04-05Us
Aspirin Low Dosetablet, delayed release81 mg/1oralHannaford Brothers Company2005-04-262016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralL.N.K. International, Inc.2011-05-022016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralArmy and Air Force Exchange Service2011-05-012016-04-05Us
Aspirin Low Dosetablet, film coated81 mg/1oralContract Pharmacy Services Pa2010-11-032016-04-05Us
Aspirin Low Dosetablet, chewable81 mg/1oralVALUE MERCHANDISERS COMPANY, INC.2001-09-042016-04-05Us
Aspirin Low Dosetablet, film coated81 mg/1oralContract Pharmacy Services Pa2010-08-102016-04-05Us
Aspirin Low Dosetablet, chewable81 mg/1oralBetter Living Brands, Llc1990-09-122018-06-26Us
Aspirin Low Dosetablet, coated81 mg/1oralSave A Lot Food Stores, Ltd.2011-05-012016-04-05Us
Aspirin Low Dosetablet81 mg/1oralSUPERVALU INC.2014-07-252016-04-05Us
Aspirin Low Dosetablet, film coated81 mg/1oralContract Pharmacy Services Pa2010-08-092016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralFRED'S, INC.2011-05-012016-04-05Us
Aspirin Low Dosetablet, chewable36 mg/1oralChain Drug Consortium1990-09-122016-04-05Us
Aspirin Low Dosetablet, chewable81 mg/1oralSUPERVALU INC.1990-09-122016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralDolgencorp, LLC2011-05-022016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralL&R Distributors, Inc.2004-01-142016-04-05Us
Aspirin Low Dosetablet81 mg/1oralAmerica Medic2012-05-152016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralHarmon Store Inc.2011-05-012016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralWALGREEN CO.2004-04-142016-04-23Us
Aspirin Low Dosetablet, film coated81 mg/1oralContract Pharmacy Services Pa2010-08-172016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralChain Drug Consortium2011-05-012016-04-05Us
Aspirin Low Dosetablet, chewable81 mg/1oralBetter Living Brands, Llc1990-09-122016-04-05Us
Aspirin Low Dosetablet, coated81 mg/1oralMedicine Shoppe International Inc2008-02-122016-04-05Us
Aspirin Low Dose Chewabletablet, chewable81 mg/1oralBetter Living Brands, Llc2001-09-142016-04-05Us
Aspirin Low Dose Chewabletablet, chewable81 mg/1oralContract Pharmacy Services Pa2010-08-092016-04-05Us
Aspirin Low Dose Chewabletablet, chewable81 mg/1oralSafecor Health, LLC2014-09-302016-04-05Us
Aspirin Low Dose Chewabletablet, chewable81 mg/1oralTime Cap Labs, Inc2010-07-162016-04-05Us
Aspirin Low Dose Enteric Coatedtablet, coated81 mg/1oralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2012-11-132016-04-05Us
Aspirin Low Dose Enteric Coatedtablet, coated81 mg/1oralClinical Solutions Wholesale2010-06-282016-04-05Us
Aspirin Low Dose Enteric Coatedtablet81 mg/1oralTime Cap Labs, Inc2010-07-162016-04-05Us
Aspirin Low Dose Enteric Coatedtablet, coated81 mg/1oralTime Cap Labs, Inc2010-06-282016-04-05Us
Aspirin Low Dose Enteric Coatedtablet81 mg/1oralSMART SENSE (Kmart)2013-03-312016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralChain Drug Consortium, LLC2013-03-152016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralWestern Family Foods, Inc.2013-03-012016-04-05Us
Aspirin Low Dose Safety Coatedtablet81 mg/1oralPreferred Plus (Kinray)2013-03-312016-04-05Us
Aspirin Low Dose Safety Coatedtablet81 mg/1oralASSURED / DOLLAR TREE (Greenbrier International, Inc.)2013-03-312016-04-05Us
Aspirin Low Dose Safety Coatedtablet81 mg/1oralThe Kroger Co.2013-03-082016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralCardinal Health (Leader)2013-04-132016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralHealthy Accents (DZA Brands, LLC)2013-03-012016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralHy Vee2013-03-152016-04-05Us
Aspirin Low Dose Safety Coatedtablet81 mg/1oralP And L Development Of New York Corporation (Ready In Case)2013-03-012016-04-05Us
Aspirin Low Dose Safety Coatedtablet81 mg/1oralP And L Development Of New York Corporation (Ready In Case)2014-07-312016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralAmerisource Bergen (Good Neighbor Pharmacy) 461222013-03-152016-04-05Us
Aspirin Low Dose Safety Coatedtablet81 mg/1oralBest Choice (Valu Merchandisers Company)2013-03-082016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralTOP CARE (Topco Associates LLC)2013-03-152016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralGeiss, Destin & Dunn, Inc (Goodsense)2013-03-152016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralFreds Inc2013-03-082016-04-05Us
Aspirin Low Dose Safety Coatedtablet, coated81 mg/1oralBJWC (Berkley & Jensen / BJ's)2013-03-312016-04-05Us
Aspirin Low Dose Sugar Freetablet, coated81 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2011-05-012016-04-05Us
Aspirin Low Strengthtablet, coated81 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2014-07-252016-04-05Us
Aspirin Low Strength Adulttablet, coated81 mg/1oralSam's West Inc2008-02-122016-04-05Us
Aspirin Low Strength Adulttablet81 mg/1oralSam's West Inc2011-05-012016-04-05Us
Aspirin Low Strength, Enterictablet, coated81 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2004-04-142018-06-03Us
Aspirin Migrainetablet500 mgoralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Nsaidtablet325 mg/1oralGeri Care Pharmaceutical1993-08-042016-04-05Us
Aspirin Nsaidtablet, film coated325 mg/1oralVALUE MERCHANDISERS COMPANY, INC.1996-02-102016-04-05Us
Aspirin Regular Strengthtablet325 mg/1oralSam's West Inc1996-02-102016-04-05Us
Aspirin Regular Strengthtablet, coated325 mg/1oralEQUATE (Walmart Stores, Inc.)2013-10-252016-04-05Us
Aspirin Regular Strengthtablet, coated325 mg/1oralSuper Valu (Equaline)2011-12-052016-04-05Us
Aspirin Regular Strengthtablet, coated325 mg/1oralMeijer2014-11-072016-04-05Us
Aspirin Regular Strengthtablet, coated325 mg/1oralCare One (American Sales Company)2011-08-022016-04-05Us
Aspirin Regular Strengthtablet325 mgoralBayer Inc Consumer Care1970-12-31Not applicableCanada
Aspirin Regular Strengthtablet, coated325 mg/1oralArmy and Air Force Exchange Service1992-12-142016-04-05Us
Aspirin Regular Strengthtablet325 mg/1oralCVS Pharmacy1991-06-152016-04-05Us
Aspirin Regular Strengthtablet, film coated325 mg/1oralCare One1996-02-102016-04-05Us
Aspirin Regular Strengthtablet, film coated325 mg/1oralWALGREEN CO.1996-02-102016-04-23Us
Aspirin Regular Strengthtablet325 mg/1oralMeijer Distribution Inc1987-07-152016-04-05Us
Aspirin Regular Strengthtablet, coated325 mg/1oralAmerisource Bergen Drug Corporation (Good Neighbor Pharmacy) 243852011-11-172016-04-05Us
Aspirin Regular Strengthtablet325 mg/1oralKroger Company1987-11-152016-04-05Us
Aspirin Regular Strengthtablet, delayed release325 mg/1oralSUPERVALU INC.2014-10-012016-04-05Us
Aspirin Regular Strength Regular Strengthtablet325 mg/1oralMajor Pharmaceuticals2006-05-242016-04-05Us
Aspirin Regular Strength Regular Strengthtablet325 mg/1oralA S Medication Solutions Llc2006-05-242016-04-05Us
Aspirin Safety Coatedtablet, coated325 mg/1oralHy Vee2014-05-312016-04-05Us
Aspirin Safety Coatedtablet, coated325 mg/1oralCVS Pharmacy2014-06-302016-04-05Us
Aspirin Safety Coatedtablet, coated81 mg/1oralWestern Family Foods, Inc.2014-05-012016-04-05Us
Aspirin Safety Coatedtablet, coated81 mg/1oralFreds Inc2014-08-312016-04-05Us
Aspirin Safety Coated Adult Low Dosetablet, delayed release81 mg/1oralWin Co Foods, Llc2014-12-152016-04-05Us
Aspirin Stomach Guard Extra Strengthtablet500 mgoralBayer Inc Consumer Care2009-10-09Not applicableCanada
Aspirin Stomach Guard Regular Strengthtablet325 mgoralBayer Inc Consumer Care2010-03-11Not applicableCanada
Aspirin Tab 325mg USPtablet325 mgoralSterling Winthrop Inc.1992-12-311996-09-10Canada
Aspirin Tablets 325mgtablet325 mgoralSterling Winthrop Inc.1992-12-311996-09-10Canada
Aspirin Thin Coatedtablet325 mg/1oralMajor Pharmaceuticals2014-05-072016-04-05Us
Asprintablet, delayed release81 mg/1oralAvema Pharma Solutions2010-01-022016-04-05Us
Astrin 5grtablet (enteric-coated)325 mgoralMedic Laboratory LtÉe1959-12-311996-09-09Canada
Bayertablet325 mg/1oralLil' Drug Store Products, Inc.2009-07-012016-04-05Us
Bayer Advanced Aspirin Extra Strengthtablet500 mg/1oralBayer Health Care Llc, Consumer Care2012-12-012016-04-23Us
Bayer Advanced Aspirin Regular Strengthtablet325 mg/1oralBayer Corporation Consumer Care Division2010-12-012016-04-23Us
Bayer Aspirin Extra Strength Capletstablet500 mg/1oralBayer Health Care Llc, Consumer Care2014-12-232016-04-23Us
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orangetablet, chewable81 mg/1oralBayer Health Care Llc, Consumer Care2015-01-112016-04-23Us
Bayer Aspirin Regimen Regular Strengthtablet, chewable325 mg/1oralBayer Health Care Llc, Consumer Care2015-01-112016-04-23Us
Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavoredtablet, chewable81 mg/1oralBayer Health Care Llc2002-07-022016-04-23Us
Bayer Fast Releasepowder500 mg/1oralBayer Corporation Consumer Care Division2010-06-302016-04-23Us
Bayer Genuine Aspirintablet325 mg/1oralR J General Corporation2014-07-312016-04-05Us
Bayer Genuine Aspirintablet325 mg/1oralBayer Health Care Consumer Care2014-07-312016-04-23Us
Bayer Genuine Aspirintablet325 mg/1oralYour Safety Company2016-03-152016-04-05Us
Bayer Genuine Aspirintablet, coated325 mg/1oralUnifirst First Aid Corporation2014-01-242016-04-05Us
Bayer Low Dosetablet81 mg/1oralBayer Health Care Llc, Consumer Care2002-07-122016-04-23Us
Bayer Plus Extra Strengthtablet, coated500 mg/1oralBayer Health Care Llc, Consumer Care2015-01-122016-04-23Us
Berkley and Jensen Aspirintablet325 mg/1oralBJWC2008-07-232016-04-05Us
Buffered Aspirintablet325 mg/1oralRite Aid1990-03-302017-03-18Us
Buffered Aspirin Regular Strengthtablet, film coated325 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1990-03-302016-04-05Us
Bufferintablet325 mg/1oralDucere Pharma LLC2013-05-152016-04-05Us
Bufferintablet325 mgoralNovartis Consumer Health Canada Inc.1986-12-312013-01-15Canada
Bufferin Extra -strengthtablet500 mgoralNovartis Consumer Health Canada Inc.1986-12-312013-01-15Canada
Bufferin Low Dose Buffered Aspirintablet81 mg/1oralNovartis Consumer Health, Inc.2011-03-112016-04-23Us
Care One Aspirintablet325 mg/1oralAmerican Sales Company2004-05-182016-04-05Us
Care One Aspirintablet, chewable81 mg/1oralAmerican Sales Company2005-11-222016-04-05Us
Care One Aspirintablet, chewable81 mg/1oralAmerican Sales Company2004-06-012016-04-05Us
Careall Aspirintablet, coated81 mg/1oralNew World Imports, Inc2016-03-012016-04-05Us
Careall Aspirintablet, chewable81 mg/1oralNew World Imports, Inc2016-03-292016-04-01Us
Chewable Adult Low Dose Aspirintablet, chewable81 mg/1oralRaritan Pharmaceuticals Inc2013-06-032016-04-05Us
Chewable Aspirintablet, chewable81 mg/1oralGenuine First Aid LLC2010-04-022016-04-05Us
Chewable Aspirintablet, chewable81 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1990-09-122018-03-04Us
Chewable Aspirintablet, chewable81 mg/1oralChain Drug Marketing Association2014-06-132016-04-05Us
Chewable Aspirin Low Dosetablet81 mg/1oralChain Drug Marketing Association Inc2001-09-042016-04-05Us
Chewable Daily Low Dose Asatablet (chewable)81 mgoralPharmascience Inc2008-10-31Not applicableCanada
Chewable Low Dose Aspirintablet, chewable81 mg/1oralFamily Dollar1990-09-122016-04-05Us
Chewable Low Dose Aspirintablet, chewable81 mg/1oralSUPERVALU INC.2001-09-042016-04-05Us
Childrens Aspirintablet, chewable81 mg/1oralCardinal Helath2011-06-022016-04-05Us
Childrens Chewable Aspirintablet, chewable81 mg/1oralCardinal Health2011-06-022016-04-05Us
Chronic Pain/fever Relieftablet81 mg/1oralWe Care Distributor Inc.2016-02-092016-04-05Us
Coated Aspirin - Ect 80mgtablet (enteric-coated)80 mgoralBayer Inc Consumer Care1996-10-021998-09-28Canada
Coated Aspirin Low-dosetablet, coated81 mg/1oralTarget Corporation2009-05-012016-04-05Us
Coated Daily Low Dose Asa 81 mgtablet (delayed-release)81 mgoralApotex Inc2013-10-17Not applicableCanada
Coated Daily Low-dose Asatablet (delayed-release)81 mgoralPharmascience Inc2004-06-072010-04-30Canada
Coryphen 325 Tabtablet (enteric-coated)325 mgoralRougier Pharma Division Of Ratiopharm Inc1979-12-311999-09-27Canada
Coryphen 650 Tabtablet (enteric-coated)650 mgoralRougier Pharma Division Of Ratiopharm Inc1979-12-311999-09-27Canada
Critical Care Aspirin To Gopowder325 mg/1oralBreakthrough Products Inc.2012-10-012016-04-05Us
Dg Health Aspirintablet, chewable81 mg/1oralDolgencorp, LLC2009-12-042016-04-05Us
Direct Safety Aspirintablet, film coated325 mg/1oralConney Safety Products, LLC2013-05-032016-04-05Us
EC-81aspirin Enteric Coatedtablet81 mg/1oralTri Marc Labs2010-08-112016-04-05Us
Ecotrintablet, coated81 mg/1oralMedtech Products Inc.2012-06-012016-04-05Us
Ecotrintablet, coated81 mg/1oralMedtech Products Inc.2012-06-012016-04-05Us
Ecotrin Regular Strengthtablet, coated325 mg/1oralMedtech Products Inc.2012-06-012016-04-05Us
Enteric Aspirintablet, coated325 mg/1oralCostco Wholesale Corporation1992-12-142016-04-05Us
Enteric Aspirintablet, coated325 mg/1oralChain Drug Marketing Association Inc1992-12-142016-04-05Us
Enteric Aspirintablet81 mg/1oralCardinal Health2011-06-022016-04-05Us
Enteric Aspirintablet, coated325 mg/1oralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.1992-12-142016-04-05Us
Enteric Aspirin Regular Strengthtablet, coated325 mg/1oralL.N.K. International, Inc.1992-12-142016-04-05Us
Enteric Coated A.S.atablet (delayed-release)650 mgoralPendopharm Division Of De Pharmascience Inc2005-07-29Not applicableCanada
Enteric Coated A.S.atablet (delayed-release)325 mgoralPendopharm Division Of De Pharmascience Inc2005-07-19Not applicableCanada
Enteric Coated A.S.a (caplet)tablet (delayed-release)325 mgoralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
Enteric Coated A.S.A. (caplet)tablet (delayed-release)650 mgoralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
Enteric Coated Asa 325 mgtablet (delayed-release)325 mgoralPendopharm Division Of De Pharmascience Inc2007-06-01Not applicableCanada
Enteric Coated Asa 325 mgtablet (delayed-release)325 mgoralGfr Pharma Ltd.2004-09-152010-06-29Canada
Enteric Coated Asa 650 mgtablet (delayed-release)650 mgoralGfr Pharma Ltd.2004-09-152010-06-29Canada
Enteric Coated Asa Tablets 325mgtablet (enteric-coated)325 mgoralApotex Inc1982-12-31Not applicableCanada
Enteric Coated Asa Tablets 325mgtablet (delayed-release)325 mgoralVita Health Products Inc1993-12-31Not applicableCanada
Enteric Coated Asa Tablets 650mgtablet (enteric-coated)650 mgoralApotex Inc1982-12-31Not applicableCanada
Enteric Coated Asa Tablets 650mgtablet (delayed-release)650 mgoralVita Health Products Inc1993-12-31Not applicableCanada
Enteric Coated Aspirintablet81 mg/1oralNash Finch Company2008-02-122018-06-10Us
Enteric Coated Aspirintablet325 mg/1oralA S Medication Solutions Llc2011-02-042016-04-05Us
Enteric Coated Aspirintablet, delayed release325 mg/1oralRUGBY LABORATORIES, INC2011-09-202016-04-23Us
Enteric Coated Aspirintablet325 mg/1oralA S Medication Solutions Llc2011-02-042016-04-05Us
Enteric Coated Aspirintablet325 mg/1oralState of Florida DOH Central Pharmacy2014-01-012016-04-05Us
Enteric Coated Aspirintablet325 mg/1oralAmerican Health Packaging2014-09-182016-04-05Us
Enteric Coated Aspirintablet325 mg/1oralQualitest Pharmaceuticals2011-02-042016-04-23Us
Enteric Coated Aspirintablet, delayed release325 mg/1oralRebel Distributors Corp2011-09-202016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, delayed release325 mg/3251oralTime Cap Labs, Inc2011-01-042016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, coated325 mg/1oralL&R Distributors, Inc.1992-12-142016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, coated325 mg/1oralBest Choice (Valu Merchandisers Company)2011-11-112016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, delayed release325 mg/3251oralCardinal Health2013-06-282016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, delayed release325 mg/3251oralCardinal Health2013-06-282016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, delayed release325 mg/1oralSafeway2015-08-052016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, coated325 mg/1oralGood Sense (Geiss, Destin & Dunn, Inc.)2011-08-222016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, delayed release325 mg/3251oralMcKesson Packaging Services a business unit of McKesson Corporation2013-06-282016-04-05Us
Enteric Coated Aspirin Regular Strengthtablet, coated325 mg/1oralMc Kesson (Sunmark)2010-09-152016-04-05Us
Enteric Coated Daily Low Dose Asa 81mgtablet (delayed-release)81 mgoralVita Health Products Inc2011-06-27Not applicableCanada
Enteric Safety Coated Aspirintablet, coated81 mg/1oralRite Aid2004-01-142018-05-27Us
Entrophentablet (delayed-release)81 mgoralPendopharm Division Of De Pharmascience Inc2000-06-20Not applicableCanada
Entrophen 325mg Capletstablet (delayed-release)325 mgoralPendopharm Division Of De Pharmascience Inc1993-12-31Not applicableCanada
Entrophen 325mg Tabletstablet (delayed-release)325 mgoralPendopharm Division Of De Pharmascience Inc1951-12-31Not applicableCanada
Entrophen 650mg Caplet Ecttablet (enteric-coated)650 mgoralPendopharm Division Of De Pharmascience Inc1991-12-31Not applicableCanada
Entrophen 80mgtablet80 mgoralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
Entrophen Chewabletablet (chewable)81 mgoralPendopharm Division Of De Pharmascience Inc2001-11-01Not applicableCanada
Entrophen Ect 500mgtablet (enteric-coated)500 mgoralPendopharm Division Of De Pharmascience Inc1990-12-31Not applicableCanada
Entrophen Ect 650mgtablet (enteric-coated)650 mgoralPendopharm Division Of De Pharmascience Inc1967-12-31Not applicableCanada
Entrophen Ect 975mgtablet (enteric-coated)975 mgoralPendopharm Division Of De Pharmascience Inc1978-12-31Not applicableCanada
Equaline Aspirintablet325 mg/1oralSupervalu Inc2004-08-132016-04-05Us
Equaline Aspirintablet, chewable81 mg/1oralSupervalu Inc2004-08-302016-04-05Us
Equaline Aspirin Adult Low Dosetablet, chewable81 mg/1oralSupervalu Inc2004-08-212016-04-05Us
Equate Aspirintablet, chewable81 mg/1oralWal Mart Stores Inc2003-03-192016-04-05Us
Equate Aspirintablet325 mg/1oralWal Mart Stores Inc1990-02-152016-04-05Us
Equate Aspirin Chewabletablet, chewable81 mg/1oralWal Mart Stores Inc2003-03-062016-04-05Us
Equate Daily Low-dosetablet (enteric-coated)81 mgoralPharmascience Inc2001-09-19Not applicableCanada
Euro Asatablet80 mgoralEuro Pharm International Canada IncNot applicableNot applicableCanada
Euro Asa 325mg Chewable Tablettablet (chewable)325 mgoralEuro Pharm International Canada IncNot applicableNot applicableCanada
Euro-asa Chewable Tablettablet (chewable)80 mgoralEuro Pharm International Canada Inc2004-04-02Not applicableCanada
Euro-asa ECtablet (delayed-release)80 mgoralEuro Pharm International Canada Inc2014-10-01Not applicableCanada
Exact Coated Daily Low-dose Asatablet (enteric-coated)81 mgoralPharmascience Inc2002-03-01Not applicableCanada
Extra Strength Asa 500mgtablet500 mgoralJamp Pharma Corporation2006-02-16Not applicableCanada
Fasprintablet, orally disintegrating81 mg/1oralNobel Laboratories, LLC2006-09-202016-04-05Us
Flanax Aspirin Pain Relievertablet325 mg/1oralBelmora LLC2012-12-062016-04-05Us
Formucare Aspirintablet, delayed release81 mg/1oralAccess Business Group International LLC2006-02-272016-04-05Us
Genuine Aspirintablet, film coated325 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2001-05-172016-04-05Us
Good Neighbor Pharmacy Aspirintablet, chewable81 mg/1oralAmerisource Bergen1997-06-262016-04-05Us
Good Neighbor Pharmacy Aspirintablet, chewable81 mg/1oralAmerisource Bergen1993-03-192016-04-05Us
Good Neighbor Pharmacy Aspirintablet, film coated81 mg/1oralAmerisource Bergen2004-10-192016-04-05Us
Good Neighbor Pharmacy Aspirintablet325 mg/1oralAmerisource Bergen2015-02-202016-04-05Us
Good Neighbor Pharmacy Aspirintablet325 mg/1oralAmerisource Bergen1989-09-152016-04-05Us
Good Neighbor Pharmacy Aspirin Enteric Safety Coatedtablet, delayed release81 mg/1oralAmerisource Bergen1994-03-292016-04-05Us
Good Neighbor Pharmacy Aspirin Orange Flavor Chewabletablet, chewable81 mg/1oralAmerisource Bergen2002-02-202016-04-05Us
Good Sense Aspirintablet, chewable81 mg/1oralL. Perrigo Company1992-11-042016-04-23Us
Good Sense Aspirintablet325 mg/1oralL. Perrigo Company1991-04-152016-04-23Us
Good Sense Aspirintablet, film coated81 mg/1oralL Perrigo Company1993-07-092016-04-23Us
Good Sense Aspirintablet, chewable81 mg/1oralL Perrigo Company1997-08-082016-04-23Us
Good Sense Aspirintablet, chewable81 mg/1oralL. Perrigo Company1999-08-252016-04-23Us
Good Sense Aspirin Enteric Safety Coatedtablet, delayed release81 mg/1oralL Perrigo Company1993-09-302016-04-23Us
Handy Solutions Genuine Aspirin Bayertablet325 mg/1oralNavajo Manufacturing Company Inc.2013-08-212016-04-05Us
Health Mart Aspirintablet, chewable81 mg/1oralMc Kesson2011-11-212016-04-05Us
Health Mart Aspirintablet, chewable81 mg/1oralMc Kesson2011-11-212016-04-05Us
Health Mart Aspirintablet325 mg/1oralMc Kesson2011-11-212016-04-05Us
Health Mart Aspirintablet, chewable81 mg/1oralMc Kesson2013-08-132016-04-05Us
Health Mart Regular Strength Enteric Coated Aspirintablet, coated325 mg/1oralMc Kesson (Health Mart)2012-06-052016-04-05Us
Health Sense Adult Chewable Low Strength Aspirintablet, chewable81 mg/1oralPrime Marketing, LLC2006-10-012016-04-05Us
Health Sense Aspirin 81tablet, coated81 mg/1oralPrime Marketing, LLC2006-07-012016-04-05Us
Health Sense Ecpirintablet, coated325 mg/1oralPrime Marketing, LLC2006-12-012016-04-05Us
Healthy Accents Aspirintablet, delayed release81 mg/1oralDZA Brands LLC2008-03-232016-04-05Us
Healthy Accents Aspirintablet, chewable81 mg/1oralDZA Brands LLC2008-02-042016-04-05Us
Healthy Accents Aspirintablet325 mg/1oralDZA Brands LLC2008-01-222016-04-05Us
Healthy Accents Aspirintablet, chewable81 mg/1oralDZA Brands LLC2011-06-062016-04-05Us
Henry Schein Aspirintablet, film coated325 mg/1oralHenry Schein, Inc.2011-07-252016-04-23Us
Jamp-A.S.A.tablet (delayed-release)80 mgoralJamp Pharma Corporation2006-09-28Not applicableCanada
Jamp-asa 81mg ECtablet (enteric-coated)81 mgoralVita Health Products Inc2015-01-13Not applicableCanada
Kroger Value Aspirintablet325 mg/1oralKroger Company2007-03-172016-04-05Us
Leader Aspirintablet325 mg/1oralCardinal Health1990-05-152016-04-05Us
Leader Aspirintablet, chewable81 mg/1oralCardinal Health2014-09-202016-04-05Us
Leader Aspirintablet, chewable81 mg/1oralCardinal Health1997-04-022016-04-05Us
Leader Aspirintablet, chewable81 mg/1oralCardinal Health1993-08-092016-04-05Us
Leader Aspirintablet, coated325 mg/1oralCardinal Health2012-04-092016-04-05Us
Leader Cardinal Health Aspirintablet, delayed release81 mg/1oralCardinal Health2001-08-222016-04-05Us
Leader Low Dose Aspirintablet, chewable81 mg/1oralCardinal Health2014-09-202016-04-05Us
Lo-asa 80mg Chewable - Tabtablet80 mgoralKinsmor Pharmaceuticals Canada Inc.1997-01-092000-06-16Canada
London Drugs Coated Daily Low-dose Asatablet (enteric-coated)81 mgoralPharmascience Inc2001-10-232014-08-04Canada
Low Dose Aspirintablet81 mg/1oralWal Mart Stores Inc2008-02-122016-04-05Us
Low Dose Aspirintablet, chewable81 mg/1oralRite Aid2001-09-042016-04-05Us
Low Dose Aspirintablet, coated81 mg/1oralTIME CAP LABORATORIES, INC2015-06-192016-04-05Us
Low Dose Aspirintablet, chewable81 mg/1oralWALGREEN CO.2001-09-042016-04-23Us
Low Dose Aspirintablet, chewable81 mg/1oralNash Finch Company2001-09-042018-04-02Us
Low Dose Aspirintablet, chewable81 mg/1oralPharbest Pharmaceuticals, Inc.2007-08-222016-04-05Us
Low Dose Aspirintablet81 mg/1oralQualitest Pharmaceuticals2009-11-032016-04-23Us
Low Dose Aspirintablet, chewable81 mg/1oralWALGREEN CO.1990-09-122016-04-23Us
Low Dose Aspirintablet81 mg/1oralPharmadel LLC2013-03-252016-04-05Us
Low Dose Aspirintablet, chewable81 mg/1oralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.1990-09-122016-04-05Us
Low Dose Aspirintablet81 mg/1oralSUPERVALU INC.2008-02-122016-04-05Us
Low Dose Aspirin 81 Mg Safety Coatedtablet, delayed release81 mg/1oralFamily Dollar (FAMILY WELLNESS)2014-07-312016-04-05Us
Low Dose Aspirin Enteric Safety Coatedtablet, delayed release81 mg/1oralTime Cap Labs, Inc2010-08-112016-04-05Us
Low Dose Aspirin Enteric Safety Coatedtablet, delayed release81 mg/1oralTime Cap Labs, Inc2010-08-102016-04-05Us
Low Dose Chewable Aspirintablet, chewable81 mg/1oralNash Finch Company1990-09-122017-09-09Us
Low Dose Miniprin Enteric Safety Coatedtablet, delayed release81 mg/1oralTime Cap Labs, Inc2010-08-112016-04-05Us
Low Strength Chewable Aspirintablet, chewable81 mg/1oralGeri Care Pharmaceutical Corp1995-01-012016-04-05Us
Lowprin 325tablet325 mgoralEuro Pharm International Canada IncNot applicableNot applicableCanada
Lowprin 325 Chewable Tablettablet (chewable)325 mgoralEuro Pharm International Canada IncNot applicableNot applicableCanada
Lowprin 80 Chewable Tablettablet (chewable)80 mgoralEuro Pharm International Canada Inc2009-10-02Not applicableCanada
Lowprin 80mgtablet80 mgoralEuro Pharm International Canada Inc2009-10-06Not applicableCanada
M-asa 80 Mg Croquabletablet (chewable)80 mgoralMantra Pharma Inc2015-02-11Not applicableCanada
Medi First Plus Aspirintablet, film coated325 mg/1oralUnifirst First Aid Corporation2008-12-302016-04-05Us
Medi-first Aspirintablet, film coated325 mg/1oralUnifirst First Aid Corporation2008-12-302016-04-05Us
Medique Aspirintablet, film coated325 mg/1oralUnifirst First Aid Corporation2008-12-302016-04-05Us
Medpurinetablet81 mg/1oralPURINEPHARMA LLC2015-04-142016-04-05Us
Micro-coated Aspirintablet325 mg/1oralMc Kesson Contract Packaging2011-09-302016-04-05Us
Micro-coated Aspirintablet, coated325 mg/1oralRUGBY LABORATORIES, INC2011-09-212016-04-23Us
Miniprintablet, coated81 mg/1oralTIME CAP LABORATORIES, INC2012-05-072016-04-05Us
North Aspirintablet325 1/1oralNorth Safety Products2011-11-072016-04-23Us
Novasentablet (delayed-release)325 mgoralTeva Canada Limited1976-12-31Not applicableCanada
Novasentablet (delayed-release)650 mgoralTeva Canada Limited1976-12-31Not applicableCanada
Pain Relief Aspirintablet325 mg/1oralRite Aid2006-02-102016-04-05Us
Pain Relief Aspirintablet, chewable81 mg/1oralRite Aid1990-09-122016-04-05Us
Pain Relief Aspirin Low Dosetablet, coated81 mg/1oralRite Aid2014-07-252016-04-05Us
Pain Relief Aspirin Low Dosetablet, coated81 mg/1oralRite Aid2008-02-122016-04-05Us
Pain Relievertablet, delayed release81 mg/1oralHealth Life Of Usa2016-02-092016-04-01Us
Pharbest Aspirin 325mgtablet, delayed release325 mg/1oralA S Medication Solutions Llc2010-09-202016-04-05Us
Pharbest Aspirin 325mgtablet, delayed release325 mg/1oralPharbest Pharmaceuticals, Inc.2010-09-202016-04-05Us
Pharbest Regular Strength Aspirintablet325 mg/1oralPharbest Pharmaceuticals, Inc2007-01-122016-04-05Us
Pharbest Regular Strength Aspirintablet325 mg/1oralA S Medication Solutions Llc2007-01-122016-04-05Us
PHL-asatablet80 mgoralPharmel Inc2003-04-21Not applicableCanada
PHL-asa E.C.tablet (delayed-release)80 mgoralPharmel Inc2003-04-21Not applicableCanada
Plus Pharma Nsaid 325 mgtablet81 mg/1oralTYA Pharmaceuticals2014-09-292016-04-05Us
Plus Pharma Nsaid Aspirintablet325 mg/1oralGemini Pharmaceuticals, Inc. dba Plus Pharma2006-03-272016-04-05Us
PMS-asatablet80 mgoralPharmascience Inc2006-08-15Not applicableCanada
PMS-asatablet81 mgoralPharmascience Inc2006-08-15Not applicableCanada
PMS-asatablet325 mgoralPharmascience Inc1969-12-31Not applicableCanada
PMS-asa ECtablet (enteric-coated)325 mgoralPharmascience Inc2006-09-28Not applicableCanada
PMS-asa ECtablet (delayed-release)650 mgoralPharmascience Inc2006-08-15Not applicableCanada
PMS-asa ECtablet (delayed-release)325 mgoralPharmascience Inc2006-08-31Not applicableCanada
PMS-asa ECtablet (delayed-release)80 mgoralPharmascience Inc2006-08-15Not applicableCanada
Praxis Asa EC 81 Mg Daily Low Dosetablet (delayed-release)81 mgoralPharmascience Inc2006-08-15Not applicableCanada
Pro-aas - 80 (croquable)tablet (chewable)80 mgoralPro Doc Limitee2008-07-03Not applicableCanada
Pro-aas EC - 80tablet (delayed-release)80 mgoralPro Doc Limitee2008-07-03Not applicableCanada
Rapid Comfort Aspirintablet, film coated325 mg/1oralLab Safety Supply, Inc.2011-10-142016-04-05Us
Regular Strength Aspirintablet, coated325 mg/1oralWal Mart Stores Inc1992-12-142016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralMajor Pharmaceuticals Inc2011-09-092016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralClinical Solutions Wholesale2011-09-092016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralREMEDYREPACK INC.2015-06-052016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralAidarex Pharmaceuticals LLC2011-09-092016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-09-092016-04-23Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralProficient Rx LP2011-09-092016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralAphena Pharma Solutions Tennessee, Llc2011-09-092016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralH.J. Harkins Company, Inc.2011-09-092016-04-05Us
Regular Strength Aspirin ECtablet, delayed release325 mg/1oralMajor Pharmaceuticals Inc2011-09-092016-04-05Us
Regular Strength Enteric Coated Aspirintablet, coated325 mg/1oralGeri Care Pharmaceutical Corp2000-07-012016-04-05Us
Regular Strength Enteric Coated Aspirintablet, coated325 mg/1oralPreferred Pharmaceuticals Inc.2015-10-072016-04-05Us
Regular Strength Enteric Coated Aspirintablet, coated325 mg/1oralAvera Mc Kennan Hospital2015-03-232016-04-05Us
Regular Strength Pain Relieftablet, coated325 mg/1oralRite Aid1992-12-142016-04-05Us
Regular Strength Tri-buffered Aspirintablet, film coated325 mg/1oralWALGREEN CO.1990-03-302016-04-23Us
Relief Asa Extra Strengthtablet500 mgoralPendopharm Division Of De Pharmascience Inc2003-02-01Not applicableCanada
Rexall Aspirintablet, chewable81 mg/1oralDolgencorp, LLC2010-08-192016-04-05Us
Rexall Coated Daily Low Dose Asatablet (enteric-coated)81 mgoralPharmascience Inc2001-09-20Not applicableCanada
Rivasa 80mg Croquable - Tabtablet (chewable)80 mgoralLaboratoire Riva Inc1999-12-01Not applicableCanada
Rivasa 81 Mg ECtablet (delayed-release)81 mgoralLaboratoire Riva Inc2014-03-20Not applicableCanada
Rivasa Fctablet80 mgoralLaboratoire Riva Inc2004-01-01Not applicableCanada
Rugby Aspirintablet, chewable81 mg/1oralRugby Laboratories2014-03-212016-04-23Us
Rx Act Aspirintablet, chewable81 mg/1oralH E B1997-05-292016-04-05Us
Safety Coated Aspirintablet81 mg/1oralValu Merchandisers Company (Best Choice)2010-08-212016-04-05Us
Safety Coated Aspirintablet81 mg/1oralCare One (American Sales Company)2010-07-302016-04-05Us
Safety Coated Low Dose Aspirintablet, coated81 mg/1oralFamily Dollar2008-02-122016-04-05Us
Smart Health Aspirin Regular Strengthtablet325 mg/1oralL Perrigo Company2003-04-092016-04-23Us
Smart Sense Aspirintablet, chewable81 mg/1oralKmart Corporation2010-06-042016-04-05Us
Smart Sense Aspirintablet325 mg/1oralKmart Corporation2010-06-042016-04-05Us
Smart Sense Aspirintablet, film coated81 mg/1oralKmart Corporation2010-10-172016-04-05Us
Smart Sense Aspirintablet, chewable81 mg/1oralKmart Corporation2010-06-042016-04-05Us
Smart Sense Chewable Aspirintablet, chewable81 mg/1oralKmart Corporation2016-03-142016-04-05Us
Solves - Aspirin Cherrystrip81 mg/1oralPace Wellness Inc.2014-05-012016-04-05Us
Solves - Aspirin Cherrystrip81 mg/1oralPace Wellness Inc.2014-05-012016-04-05Us
ST. Joseph Chewable Aspirintablet, chewable81 mg/1oralIlex Consumer Products Group, LLC2012-03-052016-04-05Us
ST. Joseph Chewable Low Dose Aspirintablet, chewable81 mg/1oralFoundation Consumer Healthcare Llc2012-03-052016-04-05Us
ST. Joseph Low Dose Aspirintablet, film coated81 mg/1oralFoundation Consumer Healthcare2014-05-302016-04-05Us
ST. Joseph Safety Coated Aspirintablet, coated81 mg/1oralBedrock Brands, LLC (ST. JOSEPH)2012-03-052016-12-31Us
Sunmark Aspirintablet, chewable81 mg/1oralMc Kesson2003-08-212016-04-05Us
Sunmark Aspirintablet, chewable81 mg/1oralMc Kesson2003-09-062016-04-05Us
Sunmark Aspirin Adult Low Strengthtablet, film coated81 mg/1oralMc Kesson2004-09-232016-04-05Us
Sunmark Aspirin Adult Low Strengthtablet, chewable81 mg/1oralMc Kesson2003-09-192016-04-05Us
Sunmark Aspirin Low Dosetablet, delayed release81 mg/1oralMc Kesson2003-08-112016-04-05Us
Sunmark Aspirin Regular Strengthtablet325 mg/1oralMc Kesson2003-06-242016-04-05Us
Topcare Aspirintablet, chewable81 mg/1oralTopco Associates LLC1992-08-242016-04-05Us
Topcare Aspirintablet, film coated81 mg/1oralTopco Associates LLC2005-05-032016-04-05Us
Topcare Aspirintablet, chewable81 mg/1oralTopco Associates LLC2005-03-292016-04-05Us
Topcare Aspirintablet, chewable81 mg/1oralTopco Associates LLC2006-04-282016-04-05Us
Tri-buffered Aspirintablet, film coated325 mg/1oralMajor Pharmaceuticals1990-03-302016-04-05Us
Uncoated Aspirintablet325 mg/1oralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1993-08-042016-04-05Us
Up and Up Aspirintablet325 mg/1oralTarget Corporation2009-06-102016-04-05Us
Up and Up Aspirintablet, chewable81 mg/1oralTarget Corporation2009-06-242016-04-05Us
Up and Up Aspirintablet, film coated81 mg/1oralTarget Corporation2009-07-222016-04-05Us
Up and Up Chewable Aspirintablet, chewable81 mg/1oralTarget Corporation2015-09-092016-04-05Us
Value Pharma Aspirin Pain Relievertablet81 mg/81mgoralAjes Pharmaceuticals,LLC2012-10-012016-04-05Us
Value Pharmapain Reliever Extra Strengthtablet325 mg/325mgoralAjes Pharmaceuticals,LLC2012-10-012016-04-05Us
Viva Asa 325 mgtablet325 mgoralViva Pharmaceutical Inc.2006-12-192011-11-17Canada
Zee Aspirintablet325 mg/1oralZee Medical Inc2012-06-122016-04-05Us
International Brands
NameCompany
AcenterineNot Available
AcetophenMerck
AdiroNot Available
AspergumNot Available
AsproNot Available
Bayer AspirinBayer HealthCare LLC.
EasprinNot Available
EmpirinNot Available
Nu-sealsNot Available
RhodineNot Available
RhonalNot Available
SolprinNot Available
Solprin acidNot Available
St. Joseph Aspirin for AdultsNot Available
TasprinNot Available
Brand mixtures
NameLabellerIngredients
10 Person AnsiGenuine First Aid LLC
217Merck Frosst Canada & Cie, Merck Frosst Canada & Co.
217 Strong TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
222 TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
25 Person AnsiGenuine First Aid LLC
282 Mep TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
282 TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
282 TabletsPendopharm Division Of De Pharmascience Inc
292 TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
292 TabletsPendopharm Division Of De Pharmascience Inc
50 Person AnsiGenuine First Aid LLC
692 TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
692 TabletLioh Inc.
7 Select Migraine Formula7 Eleven
A & C Tablets With Codeine 15mgD.C. Labs Limited
A & C Tablets With Codeine 30mgD.C. Labs Limited
A.C. & C 8mg TabVita Health Products Inc
A.C. & C. 8 mgLaboratoires Confab Inc
A.C. & C. 8mgWestcan Pharmaceuticals Ltd.
A.C.& C TabletsPharmascience Inc
A.S.A. With Methocarbamol Night-time Extra StrengthPharmetics (2011) Inc
Ac and C Tab 1/8grPharmascience Inc
Ac&c TabletsPharmascience Inc
Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate TabletsJamp Pharma Corporation
Acetylsalicylic Acid, Caffeine and 8mg Codeine PhosphatePharmetics (2011) Inc
Ache and Pain Relief To GoBreakthrough Products Inc.
Acme First Aid Contains 404 PiecesAcme United Corp.
Adalat XL PlusBayer Inc
Added Strength Pain RelieverBetter Living Brands, Llc
Advanced Pain RelieverAdvanced First Aid, Inc.
AggrenoxBoehringer Ingelheim Pharmaceuticals, Inc.
Alka SeltzerSalimex, S.A.
Alka Seltzer EvtMiles Canada Inc. Consumer Health Care Division
Alka Seltzer FlavouredMiles Canada Inc. Consumer Health Care Division
Alka-seltzerBayer Inc Consumer Care
Alka-seltzer FlavouredBayer Inc Consumer Care
Alka-seltzer Flavoured - EvtBayer Inc Consumer Care
Alka-seltzer Lemon LimeBayer Health Care Consumer Care
Alka-seltzer Morning ReliefBayer Inc Consumer Care
Alka-seltzer OriginalBayer Health Care Consumer Care
Alka-seltzer PlusLil' Drug Store Products, Inc
Alka-seltzer Plus Cold and Cough FormulaBayer Health Care Consumer Care
Alka-seltzer Plus Cold Formula (cherry Burst)Bayer Health Care Consumer Care
Alka-seltzer Plus Cold Formula (orange Zest)Bayer Health Care Consumer Care
Alka-seltzer Plus Cold Medicine Sparkling OriginalBayer Health Care Consumer Care
Alka-seltzer Plus Day Non Drowsy Cold Medicine CitrusBayer Health Care Llc, Consumer Care
Alka-seltzer Plus Night Cold Formula (lemon)Bayer Health Care Consumer Care
Alka-seltzer Plus Night Cold MedicineBayer Health Care Llc, Consumer Care
Alka-seltzer Xtra StrengthBayer Health Care Llc, Consumer Care
AnacinInsight Pharmaceuticals
Anacin AFInsight Pharmaceuticals
Anacin CapletsWyeth Consumer Healthcare Inc.
Anacin EsInsight Pharmaceuticals
Anacin Extra StrengthPaladin Labs Inc
Anacin Extra Strength CapletsWyeth Consumer Healthcare Inc.
Anacin Extra Strength TabletWyeth Consumer Healthcare Inc.
Anacin TabletWyeth Consumer Healthcare Inc.
Anacin With Codeine TabWhitehall Robins Inc.
Antidol TabletsLes Produits Gerbex Inc.
Arc Emergency Preparedness First Aid Contains 202 PiecesAmerican Red Cross
Arc First Aid Contains 1000 PiecesAmerican Red Cross
Arc First Aid Contains 101 PiecesAmerican Red Cross
Arc First Aid Contains 101 Pieces HardcaseAmerican Red Cross
Arc First Aid Contains 404 PiecesAmerican Red Cross
Arco Pain TabLaboratoire Romilo
Arthriten Inflammatory Pain FormulaAlva Amco Pharmacal Companies, Inc.
Asa and CaffeineTherapharma Inc.
Asa-caffeine-codeineLaboratoires Confab Inc
Asa, Caffeine & 8mg Codeine PhosphateCanapharm Manufacturing Inc
Asasantine CapBoehringer Ingelheim (Canada) Ltd Ltee
Ascomp With CodeineNexgen Pharma, Inc.
Aspirin and DipyridamoleRoxane Laboratories, Inc.
Aspirin BackacheBayer Inc Consumer Care
Aspirin Night-timeBayer Inc Consumer Care
Aspirin Plus Stomach Guard Ext.stgth.capletSterling Winthrop Inc.
Aspirin Plus Stomach Guard Extra StrengthBayer Inc Consumer Care
Aspirin Plus Stomach Guard TabSterling Winthrop Inc.
Aspirin Rapid ReliefBayer Inc Consumer Care
Aspirin With Stomach GuardBayer Inc Consumer Care
Aspirin With Stomach Guard Extra Strength - TabBayer Inc Consumer Care
Aspirin, Caffeine, and Dihydrocodeine BitartrateCaraco Pharmaceutical Laboratories, Ltd
Auto 157Genuine First Aid LLC
Axisal-C1/8Technilab Pharma Inc.
Back and Body Extra StrengthGreenbrier International, Inc.
Backaid Inflammatory Pain FormulaAlva Amco Pharmacal Companies, Inc.
Bayer Am Extra StengthBayer Health Care Llc, Consumer Care
Bayer Back and Body Extra StrengthBayer Health Care Llc, Consumer Care
Bayer Headache ReliefBayer Health Care Llc
Bayer Migraine FormulaBayer Health Care Llc, Consumer Care
Bayer PMBayer Health Care Llc, Consumer Care
Bayer WomensBayer Health Care Llc, Consumer Care
BcMedtech Products Inc.
Bc ArthritisMedtech Products Inc.
Bc CherryMedtech Products Inc.
Berkley and Jensen Migraine FormulaBJWC
Berkley and Jensen Migraine ReliefBJWC
Bi Electro Extra StrengthGenomma Lab Usa
BlowfishRally Labs Llc
Bromo SeltzerTower Laboratories Ltd
Butalbital CompoundMajor Pharmaceuticals
Butalbital, Aspirin and CaffeineWest ward Pharmaceutical Corp
Butalbital, Aspirin and Caffeine TabletsQualitest
Butalbital, Aspirin, and CaffeineLannett Company, Inc.
Butalbital, Aspirin, Caffeine and Codeine PhosphateLannett Company, Inc.
Butalbital, Aspirin, Caffeine, and Codeine PhosphateMayne Pharma Inc.
C T Acetylsalicylic Acid Codeine and Caf TabPharmavite Laboratories (1987) Inc.
C-2 Buffered With CodeinePharmascience Inc
C2 Buffered TabWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
C2 Buffered With Codeine TabWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
C2 Tab With CodeineWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
Calmine TabLes Laboratoires Vachon Inc.
Care One Headache Relief Added StrengthAmerican Sales Company
Care One Migraine ReliefAmerican Sales Company
Carisoprodol and AspirinEon Labs, Inc.
Carisoprodol, Aspirin and Codeine PhosphateEon Labs, Inc.
Circle K Headache ReliefLil' Drug Store Products, Inc
CitramonBorisovskiy Zavod Medicinskikh Preparatov Jsc
Coachs First Aid Contains 102 PiecesCramer Sports
Conrx Pain RelieverEagle Distributors,Inc.
Coricidin D TabSchering Plough Canada Inc
Coricidin Nd TabSchering Plough Canada Inc
Coricidin TabSchering Plough Canada Inc
Coryphen 325 Codeine 30 TabRougier Pharma Division Of Ratiopharm Inc
Coryphen 650 Codeine 30 TabRougier Pharma Division Of Ratiopharm Inc
Darvon N Compound Pulvule 405Eli Lilly Canada Inc
Dg Health Headache Relief Added StrengthDolgencorp, LLC
Dg Health Migraine ReliefDolgencorp, LLC
Dolomine 37Frega Inc.
Dristan CapsulesWhitehall Robins Inc.
Dry Socket PasteSultan Healthcare
Effervescent Antacid and Pain ReliefCardinal Health Inc.
Effervescent Cold ReliefCardinal Health, Inc
Effervescent Pain ReliefWestern Family Foods, Inc.
Effervescent Pain Relief Fast ReliefDeseret Laboratories, Inc.
Effervescent Pain Relief Fast Relief Fast ReliefMajor Pharmaceuticals
EndodanSTAT Rx USA LLC
Equagesic TabletsWyeth Ayerst Canada Inc.
Equaline Headache Formula Added StrengthSupervalu Inc
Equaline Migraine FormulaSupervalu Inc
Equate Migraine ReliefWal Mart Stores Inc
ExaprinHART Health
Excedrin Back and BodyNovartis Consumer Health, Inc.
Excedrin Extra StrengthNovartis Consumer Health, Inc.
Excedrin Extra Strength CapletsNovartis Consumer Health, Inc.
Excedrin Extra Strength GeltabsNovartis Consumer Health, Inc
Excedrin Extra Strength Pain RelieverNovartis Consumer Health, Inc.
Excedrin Menstrual CompleteNovartis Consumer Health, Inc.
Excedrin MigraineNovartis Consumer Health, Inc.
Excedrin Migraine GeltabsNovartis Consumer Health, Inc
Excedrin PM Triple Action CapletsNovartis Consumer Health, Inc.
Extra Pain ReliefTime Cap Labs
Extra Strength Aspirin BackacheBayer Inc Consumer Care
Extra Strength Back and BodyWALGREEN CO.
Extra Strength Headache ReliefTarget Corporation
Extra Strength MidolBayer Inc Consumer Care
Extra Strength Midol ReliefBayer Inc Consumer Care
Extra Strength Muscle & Back Pain Asa 500 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 500 mgVita Health Products Inc
Extra Strength Muscle & Back Pain Relief With AsaVita Health Products Inc
Extra Strength Pain RelieverRite Aid
Family Wellness Migraine ReliefFamily Dollar Services Inc
FiorinalActavis Pharma, Inc.
Fiorinal C1/2Tribute Pharmaceuticals Canada Inc
Fiorinal C1/4Tribute Pharmaceuticals Canada Inc
Fiorinal TabNovartis Pharmaceuticals Canada Inc
Fiorinal With CodeineActavis Pharma, Inc.
First Aid Contains 101 PiecesGenuine First Aid LLC
First Aid Contains 101 Pieces HardcaseGenuine First Aid LLC
First Aid Contains 303 PiecesGenuine First Aid LLC
Formu Care Pain Reliever Added StrengthAccess Business Group LLC
Genuine First Aid Emergency Preparedness Contains 167 Pieces HardcaseGenuine First Aid LLC
Genuine First Aid Industrial First AidGenuine First Aid, LLC
Gfa First Aid Kit Essentials - 33 PiecesGenuine First Aid, LLC
Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 PiecesAmerisource Bergen
Good Neighbor Pharmacy First Aid Contains 202 PiecesAmerisource Bergen
Good Neighbor Pharmacy Headache ReliefAmerisource Bergen
Good Neighbor Pharmacy Migraine ReliefAmerisource Bergen
Good Sense Headache Formula Added StrengthL Perrigo Company
Good Sense Migraine FormulaL. Perrigo Company
GoodysGlaxo Smith Kline Consumer Healthcare Lp
Goodys Back and Body PainMedtech Products Inc.
Goodys Cool OrangeLil' Drug Store Products, Inc
Goodys Cool Orange HeadacheMedtech Products Inc.
Goodys Extra StrengthMedtech Products Inc.
Goodys Extra Strength Headache Mixed Fruit BlastMedtech Products Inc.
Goodys Migraine ReliefMedtech Products Inc.
Goodys PM Pain RelieverMedtech Products Inc.
Green Guard Pain and Ache ReliefUnifirst First Aid Corporation
Harris Teeter Migraine ReliefHarris Teeter, LLC
Headache Formula Added StrengthKroger Company
Headache Formula Extra StrengthArmy and Air Force Exchange Service
Headache ReliefTarget Corporation
Headache Relief Added StrengthMedicine Shoppe International Inc
Headache Relief Extra StrengthWALGREEN CO.
Headache Relief To GoBreakthrough Products Inc.
Health Mart Migraine FormulaMc Kesson
Health Mart Migraine ReliefMc Kesson
Healthy Accents Headache Relief Added StrengthDZA Brands LLC
Healthy Accents Migraine FormulaDZA Brands LLC
Herbopyrine Tab 325mgHerbes Universelles Inc.
Instantine - TabletsBayer Inc Consumer Care
Instantine TabSterling Winthrop Inc.
K-mart Smartsense First Aid Contains 101 PiecesK Mart
Leader Headache Formula Added StrengthCardinal Health
Leader Migraine FormulaCardinal Health
Lil Drug Store Headache Relief Extra StrengthLil' Drug Store Products, Inc.
MadelonLes Laboratoires Du Saint Laurent E.H. Ltee
Medi First Pain ReliefUnifirst First Aid Corporation
Medi First Plus Pain ZapperUnifirst First Aid Corporation
Medique Medi SeltzerUnifirst First Aid Corporation
Medique Pain OffUnifirst First Aid Corporation
MethoxisalRougier Pharma Division Of Ratiopharm Inc
Methoxisal Extra StrengthTeva Canada Limited
Methoxisal-C 1/2Teva Canada Limited
Methoxisal-C 1/4Teva Canada Limited
Methoxisal-C 1/8Teva Canada Limited
Midol RegularBayer Inc Consumer Care
Migraine FormulaSafeway
Migraine ReliefWalgreen Company
Migralex Dr. MauskopMigralex Inc.
Mountain Series Weekender MedicalTender Corporation Dba Adventure Medical Kits
Muscle & Back Pain Asa 325 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 325 mgVita Health Products Inc
Muscle & Back Pain Relief Extra StrengthPendopharm Division Of De Pharmascience Inc
Muscle and Back Pain ReliefPendopharm Division Of De Pharmascience Inc
Muscle and Back Pain Relief Extra StrengthPendopharm Division Of De Pharmascience Inc
Muscle and Back Pain Relief With AsaTechnilab Pharma Inc.
Muscle and Back Pain Relief With Asa Extra StrengthTechnilab Pharma Inc.
Muscle Relaxant and AnalgesicTechnilab Pharma Inc.
Muscle Relaxant and Back Pain Relief Extra Strength TabletsPharmetics (2011) Inc
Muscle Relaxant and Back Pain Relief Regular Strength TabletsPharmetics (2011) Inc
NervineJ L Mathieu Cie Ltee
Nervine TabJ L Mathieu Cie Ltee
Neutra-seltzerTeva Canada Limited
Nezger TabLes Produits Gerbex Inc.
Norgesic3 M Pharmaceuticals
Norgesic Forte3 M Pharmaceuticals
Norgesic Forte Tab3 M Pharmaceuticals, A Division Of 3 M Canada Company
Norgesic Tab3 M Pharmaceuticals, A Division Of 3 M Canada Company
Novo Ac and C 8mg TabNovopharm Limited
Novo-propoxyn Compound CapNovopharm Limited
Orphenadrine Citrate, Aspirin and CaffeineRebel Distributors Corp
Oxycodone and AspirinPhysicians Total Care, Inc.
Oxycodone Hydrochloride and AspirinMylan Pharmaceuticals Inc.
Pain AidZee Medical Inc
Pain Aid EsfZee Medical Inc
Pain Away PlusMedex Merchandising Llc
Pain Relief Added StrengthBetter Living Brands, Llc
Pain Relief Extra StrengthL&R Distributors, Inc.
Pain Relief Fast ReliefSelect Brand
Pain Relief Maximum StrengthSelect Corporation
Pain RelieverAdvanced First Aid, Inc.
Pain Reliever Added StrengthTarget Corporation
Pain Reliever Extra StrengthCostco Wholesale Corporation
Pain Reliever PlusMajor Pharmaceuticals
Pain Stopper ExtraNorth Safety Products LLC
Pain Stoppers ExtraNorth Safety Products LLC
Pain Stoppers RegularNorth Safety Products LLC
Pain TerminatorProvision Medical Products
Pain Terminator 2 SevereProvision Medical Products
Painex Tab 0.25grIcn Canada Ltd.
Painex Tab 0.5grIcn Canada Ltd.
Pal-pravastatin-asaPaladin Labs Inc
Pamprin Max Menstrual Pain ReliefChattem, Inc.
PercodanEndo Pharmaceuticals Inc
Percodan-demiBristol Myers Squibb Canada
Phenaphen No 2 CapAyerst Laboratories
Phenaphen No 3 CapAyerst Laboratories
Phenaphen No 4 CapAyerst Laboratories
Phenaphen No.2 CapWyeth Ayerst Canada Inc.
Phenaphen No.3 CapWyeth Ayerst Canada Inc.
Phenaphen No.4 CapWyeth Ayerst Canada Inc.
Picot Plus EffervescentBristol Myers Squibb De Mexico, S. De R.L. De C.V.
PMS-pharnal CapsulesPharmascience Inc
PMS-pharnal TabletsPharmascience Inc
PMS-pharnal-C 1/4 CapsulesPharmascience Inc
PMS-pharnal-C1/2 CapsulesPharmascience Inc
Premier Value Antacid and Pain Relief MedicineChain Drug Consortium, LLC
Pronal - C1/2 CapsulesPro Doc Limitee
Pronal C1/4 CapsulesPro Doc Limitee
Pronal CapsulesPro Doc Limitee
Pronal TabletsPro Doc Limitee
ProtectionGenuine First Aid LLC
Quality Choice Effervescent Cold Relief PlusChain Drug Marketing Association
Ratio-oxycodanTeva Canada Limited
Ratio-tecnalTeva Canada Limited
Ratio-tecnal C 1/2Teva Canada Limited
Ratio-tecnal C 1/4Teva Canada Limited
Ready America First Aid Outdoor- 107 PiecesGenuine First Aid, LLC
Ready America First Aid Pocket - 33 PiecesGenuine First Aid, LLC
Regular Strength AspirinWALGREEN CO.
RivacodanLaboratoire Riva Inc
Robaxisal C 1/2Pfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robaxisal C 1/4Pfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robaxisal C-1/8 TabletsWyeth Consumer Healthcare Inc.
Robaxisal CapletsWyeth Consumer Healthcare Inc.
Robaxisal Extra StrengthPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robaxisal TabletsWyeth Consumer Healthcare Inc.
Rx Act Headache Formula Added StrengthH E B
Shoprite Migraine FormulaWakefern Food Corporation
Signature Care Migraine ReliefSafeway
Smart Sense Migraine FormulaKmart Corporation
Smart Sense Migraine ReliefKmart Corporation
Sohmed Pain RelieverSOHM Inc.
Spasmhalt-asa-8Pendopharm Division Of De Pharmascience Inc
StanbackMedtech Products Inc.
Sunmark Headache ReliefMc Kesson
Sunmark Migraine ReliefMc Kesson
Super Extra Strength Aspirin BackacheBayer Inc Consumer Care
SynalgosCaraco Pharma Inc.
Tabcin 500Salimex, S.A.
Thrulife Extra Strength Headache ReliefPolygen Pharmaceuticals LLC
Topcare Headache FormulaTopco Associates LLC
Topcare Migraine FormulaTopco Associates LLC
Tri-buffered Asa TabZee Medical Inc
Trianal C½Laboratoire Riva Inc
Trianal C¼Laboratoire Riva Inc
Trianal CapsulesLaboratoire Riva Inc
Trianal TabletLaboratoire Riva Inc
Up and Up Migraine ReliefTarget Corporation
Uricalm IntensiveAlva Amco Pharmacal Companies, Inc.
VanquishMOBERG PHARMA NORTH AMERICA LLC
Vida Mia Pain ReliefNavarro Discount Pharmacies, LLC
Winco Foods Effervescent Antacid and Pain ReliefWin Co Foods, Llc
Winco Foods Effervescent Cold ReliefWin Co Foods, Llc
Zee Pain AidZee Medical Inc
Zee-seltzer Antacid and Pain RelieverZEE MEDICAL
SaltsNot Available
Categories
UNIIR16CO5Y76E
CAS number50-78-2
WeightAverage: 180.1574
Monoisotopic: 180.042258744
Chemical FormulaC9H8O4
InChI KeyInChIKey=BSYNRYMUTXBXSQ-UHFFFAOYSA-N
InChI
InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
IUPAC Name
2-(acetyloxy)benzoic acid
SMILES
CC(=O)OC1=CC=CC=C1C(O)=O
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as phenol esters. These are aromatic compounds containing a benzene ring substituted by a hydroxyl group and an ester group.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassPhenol esters
Direct ParentPhenol esters
Alternative Parents
Substituents
  • Phenol ester
  • Benzoic acid
  • Benzoic acid or derivatives
  • Benzoyl
  • Dicarboxylic acid or derivatives
  • Acetate salt
  • Carboxylic acid ester
  • Carboxylic acid
  • Carboxylic acid derivative
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Pharmacology
IndicationFor use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and is also used to reduce the risk of death and/or nonfatal myocardial infarction in patients with a previous infarction or unstable angina pectoris.
PharmacodynamicsAcetylsalicylic acid is an analgesic, antipyretic, antirheumatic, and anti-inflammatory agent. Acetylsalicylic acid's mode of action as an antiinflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. Acetylsalicylic acid appears to produce analgesia by virtue of both a peripheral and CNS effect. Peripherally, acetylsalicylic acid acts by inhibiting the synthesis and release of prostaglandins. Acting centrally, it would appear to produce analgesia at a hypothalamic site in the brain, although the mode of action is not known. Acetylsalicylic acid also acts on the hypothalamus to produce antipyresis; heat dissipation is increased as a result of vasodilation and increased peripheral blood flow. Acetylsalicylic acid's antipyretic activity may also be related to inhibition of synthesis and release of prostaglandins.
Mechanism of actionThe analgesic, antipyretic, and anti-inflammatory effects of acetylsalicylic acid are due to actions by both the acetyl and the salicylate portions of the intact molecule as well as by the active salicylate metabolite. Acetylsalicylic acid directly and irreversibly inhibits the activity of both types of cyclooxygenase (COX-1 and COX-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. This makes acetylsalicylic acid different from other NSAIDS (such as diclofenac and ibuprofen) which are reversible inhibitors. Salicylate may competitively inhibit prostaglandin formation. Acetylsalicylic acid's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms; the therapeutic effects are not due to pituitary-adrenal stimulation. The platelet aggregation-inhibiting effect of acetylsalicylic acid specifically involves the compound's ability to act as an acetyl donor to cyclooxygenase; the nonacetylated salicylates have no clinically significant effect on platelet aggregation. Irreversible acetylation renders cyclooxygenase inactive, thereby preventing the formation of the aggregating agent thromboxane A2 in platelets. Since platelets lack the ability to synthesize new proteins, the effects persist for the life of the exposed platelets (7-10 days). Acetylsalicylic acid may also inhibit production of the platelet aggregation inhibitor, prostacyclin (prostaglandin I2), by blood vessel endothelial cells; however, inhibition prostacyclin production is not permanent as endothelial cells can produce more cyclooxygenase to replace the non-functional enzyme.
Related Articles
AbsorptionAbsorption is generally rapid and complete following oral administration but may vary according to specific salicylate used, dosage form, and other factors such as tablet dissolution rate and gastric or intraluminal pH.
Volume of distributionNot Available
Protein bindingHigh (99.5%) to albumin. Decreases as plasma salicylate concentration increases, with reduced plasma albumin concentration or renal dysfunction, and during pregnancy.
Metabolism

Acetylsalicylic acid is rapidly hydrolyzed primarily in the liver to salicylic acid, which is conjugated with glycine (forming salicyluric acid) and glucuronic acid and excreted largely in the urine.

SubstrateEnzymesProduct
Acetylsalicylic acid
Not Available
1-Salicylate glucuronideDetails
Route of eliminationNot Available
Half lifeThe plasma half-life is approximately 15 minutes; that for salicylate lengthens as the dose increases: doses of 300 to 650 mg have a half-life of 3.1 to 3.2 hours; with doses of 1 gram, the half-life is increased to 5 hours and with 2 grams it is increased to about 9 hours.
ClearanceNot Available
ToxicityOral, mouse: LD50 = 250 mg/kg; Oral, rabbit: LD50 = 1010 mg/kg; Oral, rat: LD50 = 200 mg/kg. Effects of overdose include: tinnitus, abdominal pain, hypokalemia, hypoglycemia, pyrexia, hyperventilation, dysrhythmia, hypotension, hallucination, renal failure, confusion, seizure, coma, and death.
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Acetylsalicylic Acid Action PathwayDrug actionSMP00083
SNP Mediated Effects
Interacting Gene/EnzymeSNP RS IDAllele nameDefining changeEffectReference(s)
Cytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
rs1057910 CYP2C9*1C AllelePoor drug metabolizer, lower dose requirements12893985
Integrin beta-3
Gene symbol: ITGB3
UniProt: P05106
rs5918 Not AvailableT > CPatients are more resistant to the anti-thrombotic effects of aspirin11723016
SNP Mediated Adverse Drug Reactions
Interacting Gene/EnzymeSNP RS IDAllele nameDefining changeAdverse ReactionReference(s)
Leukotriene C4 synthase
Gene symbol: LTC4S
UniProt: Q16873
rs730012 Not AvailableC alleleAspirin-induced urticaria16433794
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9645
Blood Brain Barrier+0.9376
Caco-2 permeable-0.6607
P-glycoprotein substrateNon-substrate0.685
P-glycoprotein inhibitor INon-inhibitor0.9118
P-glycoprotein inhibitor IINon-inhibitor0.9615
Renal organic cation transporterNon-inhibitor0.914
CYP450 2C9 substrateNon-substrate0.7518
CYP450 2D6 substrateNon-substrate0.9116
CYP450 3A4 substrateNon-substrate0.7225
CYP450 1A2 substrateNon-inhibitor0.9046
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorNon-inhibitor0.9576
CYP450 2C19 inhibitorNon-inhibitor0.9445
CYP450 3A4 inhibitorNon-inhibitor0.9611
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9557
Ames testNon AMES toxic0.9326
CarcinogenicityNon-carcinogens0.8356
BiodegradationReady biodegradable0.9067
Rat acute toxicity2.6386 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9433
hERG inhibition (predictor II)Non-inhibitor0.9799
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Bayer healthcare llc
Packagers
Dosage forms
FormRouteStrength
Tabletoral300 mg
Kit
Tablet (delayed-release); kit; tablet (extended-release)oral
Capsule (extended release); capsule (immediate release)oral
Tablet (effervescent)oral
Tablet, effervescentoral
Granule, effervescentoral
Tabletoral325 mg
Tablet
Tablet (enteric-coated)600 mg
Suppositoryrectal150 mg
Suppositoryrectal650 mg
Tablet325 mg
Tablet (chewable)oral80 mg
Tablet (delayed-release)oral80 mg
Tablet (delayed-release)oral162 mg
Tablet, film coatedoral500 mg/1
Tablet, film coatedoral325 mg/1
Gumoral325 mg
Suppositoryrectal300 mg/1
Suppositoryrectal600 mg/1
Tabletoral325 g/1
Tablet, coatedoral325 ng/1
Tablet, coatedoral81 mg/1
Tablet, extended releaseoral81 mg/1
Tablet (enteric-coated)oral81 mg
Capsuleoral
Tablet (enteric-coated); tablet (extended-release)oral325 mg
Tablet (enteric-coated); tablet (extended-release)oral500 mg
Tablet (delayed-release)oral500 mg
Tablet, delayed releaseoral81 mg/811
Tablet, coatedoral325 mg/1
Granulesoral500 mg
Tabletoral500 mg
Tablet, coatedoral500 mg/5001
Tablet, chewableoral36 mg/1
Tabletoral500 mg/1
Tablet, chewableoral325 mg/1
Powderoral500 mg/1
Tablet, coatedoral500 mg/1
Tabletoral81 mg/1
Tabletoral
Tablet (enteric-coated)oral80 mg
Powderoral325 mg/1
Pastedental
Capsule, extended releaseoral162.5 mg/1
Tablet (enteric-coated)oral325 mg
Tablet (delayed-release)oral650 mg
Tablet, delayed releaseoral325 mg/1
Tablet, delayed releaseoral325 mg/3251
Tablet (delayed-release)oral81 mg
Tablet (delayed-release)oral325 mg
Tablet (enteric-coated)oral650 mg
Tablet (chewable)oral81 mg
Tablet (enteric-coated)oral500 mg
Tablet (enteric-coated)oral975 mg
Tablet (chewable)oral325 mg
Tablet, coatedoral
Tablet, film coatedoral
Capsule, gelatin coatedoral
Tablet, orally disintegratingoral81 mg/1
Tabletoral325 mg/1
Tablet, chewableoral81 mg/1
Tablet, film coatedoral81 mg/1
Tablet, delayed releaseoral81 mg/1
Capsule, coatedoral
Powderoral
Tablet300 mg
Tabletoral325 1/1
Tablet, multilayeroral
Tablet (delayed-release); kit; tabletoral
Tabletoral81 mg
Tabletoral80 mg
Striporal81 mg/1
Tabletoral81 mg/81mg
Tabletoral325 mg/325mg
Prices
Unit descriptionCostUnit
Entrophen 10 650 mg Enteric-Coated Tablet0.09USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US5972916 No1997-07-142017-07-14Us
US6015577 No1997-01-182017-01-18Us
US8865187 No2002-03-232022-03-23Us
US9101637 No2002-03-232022-03-23Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point135 °CPhysProp
boiling point140 °CNot Available
water solubility4600 mg/L (at 25 °C)YALKOWSKY,SH & DANNENFELSER,RM (1992)
logP1.19HANSCH,C ET AL. (1995)
Caco2 permeability-5.06ADME Research, USCD
pKa3.49 (at 25 °C)MERCK INDEX (1983)
Predicted Properties
PropertyValueSource
Water Solubility1.46 mg/mLALOGPS
logP1.43ALOGPS
logP1.24ChemAxon
logS-2.1ALOGPS
pKa (Strongest Acidic)3.41ChemAxon
pKa (Strongest Basic)-7.1ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area63.6 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity44.45 m3·mol-1ChemAxon
Polarizability17.1 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Download (8.27 KB)
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)splash10-azq0000000-ffcb8d28ab7e460b0da8View in MoNA
GC-MSGC-MS Spectrum - GC-MS (1 TMS)splash10-bz30000000-910e8ce2493a05870b33View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-oz00000000-324f46e8def1652ed4bfView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-z300000000-cdf64eaf75083da6f355View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-z000000000-ee75806b6fb8a38fd697View in MoNA
LC-MS/MSLC-MS/MS Spectrum - EI-B (Unknown) , Positivesplash10-zg00000000-64327d3bef0063cf4fe1View in MoNA
LC-MS/MSLC-MS/MS Spectrum - CI-B (Unknown) , Positivesplash10-0z00000000-113943b65024522c1712View in MoNA
MSMass Spectrum (Electron Ionization)splash10-qz00000000-74f8a29aa18d0c3afe98View in MoNA
1D NMR1H NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
1D NMR13C NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

Marino Gobetti, Guido Vandoni, “Acetylsalicylic acid thioesters, a process for their preparation and pharmaceutical compositions containing them.” U.S. Patent US4563443, issued March, 1981.

US4563443
General References
  1. Macdonald S: Aspirin use to be banned in under 16 year olds. BMJ. 2002 Nov 2;325(7371):988. [PubMed:12411346 ]
  2. Sneader W: The discovery of aspirin: a reappraisal. BMJ. 2000 Dec 23-30;321(7276):1591-4. [PubMed:11124191 ]
  3. Aukerman G, Knutson D, Miser WF: Management of the acute migraine headache. Am Fam Physician. 2002 Dec 1;66(11):2123-30. [PubMed:12484694 ]
  4. Authors unspecified: Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet. 1988 Aug 13;2(8607):349-60. [PubMed:2899772 ]
  5. Dorsch MP, Lee JS, Lynch DR, Dunn SP, Rodgers JE, Schwartz T, Colby E, Montague D, Smyth SS: Aspirin resistance in patients with stable coronary artery disease with and without a history of myocardial infarction. Ann Pharmacother. 2007 May;41(5):737-41. Epub 2007 Apr 24. [PubMed:17456544 ]
External Links
ATC CodesA01AD05B01AC06B01AC56C10BX01C10BX02C10BX04C10BX05C10BX06C10BX08M01BA03N02BA01N02BA51N02BA71
AHFS Codes
  • 28:08.04.24
  • 92:02.00*
PDB EntriesNot Available
FDA labelDownload (889 KB)
MSDSDownload (18.9 KB)
Interactions
Drug Interactions
Drug
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Acetylsalicylic acid.
AcarboseAcetylsalicylic acid may increase the hypoglycemic activities of Acarbose.
AcebutololThe risk or severity of adverse effects can be increased when Acebutolol is combined with Acetylsalicylic acid.
AcenocoumarolAcetylsalicylic acid may increase the anticoagulant activities of Acenocoumarol.
AcepromazineAcepromazine may increase the hypotensive activities of Acetylsalicylic acid.
AcetazolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Acetazolamide.
AlbiglutideAcetylsalicylic acid may increase the hypoglycemic activities of Albiglutide.
Alendronic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Alendronate.
AlogliptinAcetylsalicylic acid may increase the hypoglycemic activities of Alogliptin.
AlteplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Alteplase.
AmilorideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Amiloride.
Aminosalicylic AcidAcetylsalicylic acid may increase the anticoagulant activities of Aminosalicylic Acid.
AmitriptylineAmitriptyline may increase the antiplatelet activities of Acetylsalicylic acid.
Ammonium chlorideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ammonium chloride.
AmphetamineAmphetamine may increase the analgesic activities of Acetylsalicylic acid.
AnagrelideThe risk or severity of adverse effects can be increased when Anagrelide is combined with Acetylsalicylic acid.
AnistreplaseAcetylsalicylic acid may increase the anticoagulant activities of Anistreplase.
ApixabanAcetylsalicylic acid may increase the anticoagulant activities of Apixaban.
ArgatrobanAcetylsalicylic acid may increase the anticoagulant activities of Argatroban.
AzelastineAcetylsalicylic acid may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Acetylsalicylic acid.
BenazeprilAcetylsalicylic acid may decrease the antihypertensive activities of Benazepril.
BendroflumethiazideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Bendroflumethiazide.
BenzphetamineThe risk or severity of adverse effects can be increased when Benzphetamine is combined with Acetylsalicylic acid.
BetamethasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Betamethasone.
Bismuth SubsalicylateAcetylsalicylic acid may increase the anticoagulant activities of Bismuth Subsalicylate.
BivalirudinAcetylsalicylic acid may increase the anticoagulant activities of Bivalirudin.
BortezomibThe metabolism of Acetylsalicylic acid can be decreased when combined with Bortezomib.
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Acetylsalicylic acid.
BromocriptineAcetylsalicylic acid may increase the hypoglycemic activities of Bromocriptine.
BumetanideAcetylsalicylic acid may decrease the diuretic activities of Bumetanide.
ButorphanolButorphanol may decrease the analgesic activities of Acetylsalicylic acid.
CaffeineThe risk or severity of adverse effects can be increased when Caffeine is combined with Acetylsalicylic acid.
CanagliflozinAcetylsalicylic acid may increase the hypoglycemic activities of Canagliflozin.
CangrelorThe risk or severity of adverse effects can be increased when Cangrelor is combined with Acetylsalicylic acid.
CaptoprilAcetylsalicylic acid may decrease the antihypertensive activities of Captopril.
CarisoprodolThe serum concentration of the active metabolites of Carisoprodol can be increased when Carisoprodol is used in combination with Acetylsalicylic acid.
CathinoneCathinone may increase the analgesic activities of Acetylsalicylic acid.
CelecoxibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Celecoxib.
ChlorothiazideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Chlorothiazide.
ChlorphentermineThe risk or severity of adverse effects can be increased when Chlorphentermine is combined with Acetylsalicylic acid.
ChlorpropamideAcetylsalicylic acid may increase the hypoglycemic activities of Chlorpropamide.
ChlorthalidoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Chlorthalidone.
CilazaprilAcetylsalicylic acid may decrease the antihypertensive activities of Cilazapril.
CilostazolThe risk or severity of adverse effects can be increased when Cilostazol is combined with Acetylsalicylic acid.
CitalopramCitalopram may increase the antiplatelet activities of Acetylsalicylic acid.
Citric AcidAcetylsalicylic acid may increase the anticoagulant activities of Citric Acid.
ClenbuterolThe risk or severity of adverse effects can be increased when Clenbuterol is combined with Acetylsalicylic acid.
ClomipramineClomipramine may increase the antiplatelet activities of Acetylsalicylic acid.
ClopidogrelThe risk or severity of adverse effects can be increased when Clopidogrel is combined with Acetylsalicylic acid.
CollagenaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Collagenase.
CorticotropinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Corticotropin.
Cortisone acetateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Cortisone acetate.
CyclothiazideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Cyclothiazide.
Dabigatran etexilateAcetylsalicylic acid may increase the anticoagulant activities of Dabigatran etexilate.
DalteparinAcetylsalicylic acid may increase the anticoagulant activities of Dalteparin.
DanaparoidAcetylsalicylic acid may increase the anticoagulant activities of Danaparoid.
DapagliflozinAcetylsalicylic acid may increase the hypoglycemic activities of Dapagliflozin.
DasatinibDasatinib may increase the anticoagulant activities of Acetylsalicylic acid.
Deoxycholic AcidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Deoxycholic Acid.
DesirudinAcetylsalicylic acid may increase the anticoagulant activities of Desirudin.
DesmopressinThe risk or severity of adverse effects can be increased when Desmopressin is combined with Acetylsalicylic acid.
DesvenlafaxineDesvenlafaxine may increase the antiplatelet activities of Acetylsalicylic acid.
DexamethasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Dexamethasone.
DexketoprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Dexketoprofen.
DiclofenacThe risk or severity of adverse effects can be increased when Diclofenac is combined with Acetylsalicylic acid.
DiclofenamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Diclofenamide.
DicoumarolAcetylsalicylic acid may increase the anticoagulant activities of Dicoumarol.
DiflunisalThe risk or severity of adverse effects can be increased when Diflunisal is combined with Acetylsalicylic acid.
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Acetylsalicylic acid.
DiltiazemDiltiazem may increase the anticoagulant activities of Acetylsalicylic acid.
DipyridamoleThe risk or severity of adverse effects can be increased when Dipyridamole is combined with Acetylsalicylic acid.
DisopyramideAcetylsalicylic acid may increase the hypoglycemic activities of Disopyramide.
DobutamineThe risk or severity of adverse effects can be increased when Dobutamine is combined with Acetylsalicylic acid.
DopamineThe risk or severity of adverse effects can be increased when Dopamine is combined with Acetylsalicylic acid.
DoxepinDoxepin may increase the antiplatelet activities of Acetylsalicylic acid.
DoxofyllineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Doxofylline.
DulaglutideAcetylsalicylic acid may increase the hypoglycemic activities of Dulaglutide.
DuloxetineDuloxetine may increase the antiplatelet activities of Acetylsalicylic acid.
Edetic AcidAcetylsalicylic acid may increase the anticoagulant activities of Edetic Acid.
EdoxabanAcetylsalicylic acid may increase the anticoagulant activities of Edoxaban.
EluxadolineAcetylsalicylic acid may increase the activities of Eluxadoline.
EmpagliflozinAcetylsalicylic acid may increase the hypoglycemic activities of Empagliflozin.
EnalaprilAcetylsalicylic acid may decrease the antihypertensive activities of Enalapril.
EnalaprilatAcetylsalicylic acid may increase the nephrotoxic activities of Enalaprilat.
EnoxaparinAcetylsalicylic acid may increase the anticoagulant activities of Enoxaparin.
EpinephrineThe risk or severity of adverse effects can be increased when Epinephrine is combined with Acetylsalicylic acid.
EptifibatideThe risk or severity of adverse effects can be increased when Eptifibatide is combined with Acetylsalicylic acid.
ErythromycinAcetylsalicylic acid may increase the hypoglycemic activities of Erythromycin.
EscitalopramEscitalopram may increase the antiplatelet activities of Acetylsalicylic acid.
Etacrynic acidAcetylsalicylic acid may decrease the diuretic activities of Ethacrynic acid.
EthanolThe risk or severity of adverse effects can be increased when Ethanol is combined with Acetylsalicylic acid.
EthoxzolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ethoxzolamide.
Ethyl biscoumacetateAcetylsalicylic acid may increase the anticoagulant activities of Ethyl biscoumacetate.
EtodolacThe risk or severity of adverse effects can be increased when Etodolac is combined with Acetylsalicylic acid.
ExenatideAcetylsalicylic acid may increase the hypoglycemic activities of Exenatide.
FenoprofenThe risk or severity of adverse effects can be increased when Fenoprofen is combined with Acetylsalicylic acid.
FenoterolThe risk or severity of adverse effects can be increased when Fenoterol is combined with Acetylsalicylic acid.
FloctafenineThe risk or severity of adverse effects can be increased when Floctafenine is combined with Acetylsalicylic acid.
FludrocortisoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fludrocortisone.
FluoxetineFluoxetine may increase the antiplatelet activities of Acetylsalicylic acid.
FlurbiprofenThe risk or severity of adverse effects can be increased when Flurbiprofen is combined with Acetylsalicylic acid.
FluvoxamineFluvoxamine may increase the antiplatelet activities of Acetylsalicylic acid.
Fondaparinux sodiumAcetylsalicylic acid may increase the anticoagulant activities of Fondaparinux sodium.
FormoterolThe risk or severity of adverse effects can be increased when Formoterol is combined with Acetylsalicylic acid.
FosinoprilAcetylsalicylic acid may decrease the antihypertensive activities of Fosinopril.
FurosemideAcetylsalicylic acid may decrease the diuretic activities of Furosemide.
Ginkgo bilobaGinkgo biloba may increase the anticoagulant activities of Acetylsalicylic acid.
GliclazideAcetylsalicylic acid may increase the hypoglycemic activities of Gliclazide.
GlimepirideAcetylsalicylic acid may increase the hypoglycemic activities of Glimepiride.
GlipizideAcetylsalicylic acid may increase the hypoglycemic activities of Glipizide.
GlucosamineGlucosamine may increase the antiplatelet activities of Acetylsalicylic acid.
GlyburideAcetylsalicylic acid may increase the hypoglycemic activities of Glyburide.
HeparinAcetylsalicylic acid may increase the anticoagulant activities of Heparin.
HomoharringtonineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Homoharringtonine.
HyaluronidaseThe therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Acetylsalicylic acid.
HydrochlorothiazideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Hydrochlorothiazide.
HydrocortisoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Hydrocortisone.
HydroflumethiazideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Hydroflumethiazide.
Ibritumomab tiuxetanThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ibritumomab.
IbrutinibThe risk or severity of adverse effects can be increased when Ibrutinib is combined with Acetylsalicylic acid.
IbuprofenThe risk or severity of adverse effects can be increased when Ibuprofen is combined with Acetylsalicylic acid.
IcosapentThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Icosapent.
ImipramineImipramine may increase the antiplatelet activities of Acetylsalicylic acid.
IndapamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Indapamide.
IndomethacinThe risk or severity of adverse effects can be increased when Indomethacin is combined with Acetylsalicylic acid.
Insulin AspartAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Aspart.
Insulin DegludecAcetylsalicylic acid may increase the hypoglycemic activities of Insulin degludec.
Insulin DetemirAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Detemir.
Insulin GlargineAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Glargine.
Insulin GlulisineAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Glulisine.
Insulin HumanAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Regular.
Insulin LisproAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Lispro.
IobenguaneThe therapeutic efficacy of Iobenguane can be decreased when used in combination with Acetylsalicylic acid.
IsoprenalineThe risk or severity of adverse effects can be increased when Isoprenaline is combined with Acetylsalicylic acid.
KetoprofenThe risk or severity of adverse effects can be increased when Ketoprofen is combined with Acetylsalicylic acid.
KetorolacThe risk or severity of adverse effects can be increased when Ketorolac is combined with Acetylsalicylic acid.
LabetalolThe risk or severity of adverse effects can be increased when Labetalol is combined with Acetylsalicylic acid.
LanreotideAcetylsalicylic acid may increase the hypoglycemic activities of Lanreotide.
LevomilnacipranLevomilnacipran may increase the antiplatelet activities of Acetylsalicylic acid.
LimaprostLimaprost may increase the antiplatelet activities of Acetylsalicylic acid.
LiraglutideAcetylsalicylic acid may increase the hypoglycemic activities of Liraglutide.
LisinoprilAcetylsalicylic acid may decrease the antihypertensive activities of Lisinopril.
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Acetylsalicylic acid.
Magnesium salicylateAcetylsalicylic acid may increase the anticoagulant activities of Magnesium salicylate.
MecaserminAcetylsalicylic acid may increase the hypoglycemic activities of Mecasermin.
Mefenamic acidThe risk or severity of adverse effects can be increased when Mefenamic acid is combined with Acetylsalicylic acid.
MeloxicamThe risk or severity of adverse effects can be increased when Meloxicam is combined with Acetylsalicylic acid.
MephentermineThe risk or severity of adverse effects can be increased when Mephentermine is combined with Acetylsalicylic acid.
MetaraminolThe risk or severity of adverse effects can be increased when Metaraminol is combined with Acetylsalicylic acid.
MetforminAcetylsalicylic acid may increase the hypoglycemic activities of Metformin.
MethamphetamineThe risk or severity of adverse effects can be increased when Methamphetamine is combined with Acetylsalicylic acid.
MethazolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Methazolamide.
MethotrexateThe serum concentration of Methotrexate can be increased when it is combined with Acetylsalicylic acid.
MethoxamineThe risk or severity of adverse effects can be increased when Methoxamine is combined with Acetylsalicylic acid.
MethylprednisoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Methylprednisolone.
MetolazoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Metolazone.
MexiletineThe metabolism of Acetylsalicylic acid can be decreased when combined with Mexiletine.
MidodrineThe risk or severity of adverse effects can be increased when Midodrine is combined with Acetylsalicylic acid.
MifepristoneAcetylsalicylic acid may increase the hypoglycemic activities of Mifepristone.
MiglitolAcetylsalicylic acid may increase the hypoglycemic activities of Miglitol.
MilnacipranMilnacipran may increase the antiplatelet activities of Acetylsalicylic acid.
MoexiprilAcetylsalicylic acid may decrease the antihypertensive activities of Moexipril.
NabumetoneThe risk or severity of adverse effects can be increased when Nabumetone is combined with Acetylsalicylic acid.
NadroparinAcetylsalicylic acid may increase the anticoagulant activities of Nadroparin.
NaphazolineThe risk or severity of adverse effects can be increased when Naphazoline is combined with Acetylsalicylic acid.
NaproxenThe risk or severity of adverse effects can be increased when Naproxen is combined with Acetylsalicylic acid.
NateglinideAcetylsalicylic acid may increase the hypoglycemic activities of Nateglinide.
NicorandilThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Nicorandil.
NorepinephrineThe risk or severity of adverse effects can be increased when Norepinephrine is combined with Acetylsalicylic acid.
ObinutuzumabThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Obinutuzumab.
OctreotideAcetylsalicylic acid may increase the hypoglycemic activities of Octreotide.
Omega-3 fatty acidsOmega-3 fatty acids may increase the antiplatelet activities of Acetylsalicylic acid.
OrciprenalineThe risk or severity of adverse effects can be increased when Orciprenaline is combined with Acetylsalicylic acid.
OxaprozinThe risk or severity of adverse effects can be increased when Oxaprozin is combined with Acetylsalicylic acid.
OxymetazolineThe risk or severity of adverse effects can be increased when Oxymetazoline is combined with Acetylsalicylic acid.
ParoxetineParoxetine may increase the antiplatelet activities of Acetylsalicylic acid.
PasireotideAcetylsalicylic acid may increase the hypoglycemic activities of Pasireotide.
PentamidineAcetylsalicylic acid may increase the hypoglycemic activities of Pentamidine.
Pentosan PolysulfateThe risk or severity of adverse effects can be increased when Pentosan Polysulfate is combined with Acetylsalicylic acid.
PentoxifyllinePentoxifylline may increase the antiplatelet activities of Acetylsalicylic acid.
PerindoprilAcetylsalicylic acid may decrease the antihypertensive activities of Perindopril.
PhenindioneAcetylsalicylic acid may increase the anticoagulant activities of Phenindione.
PhenmetrazineThe risk or severity of adverse effects can be increased when Phenmetrazine is combined with Acetylsalicylic acid.
PhenprocoumonAcetylsalicylic acid may increase the anticoagulant activities of Phenprocoumon.
PhentermineThe risk or severity of adverse effects can be increased when Phentermine is combined with Acetylsalicylic acid.
PhenylephrineThe risk or severity of adverse effects can be increased when Phenylephrine is combined with Acetylsalicylic acid.
PhenylpropanolamineThe risk or severity of adverse effects can be increased when Phenylpropanolamine is combined with Acetylsalicylic acid.
PioglitazoneAcetylsalicylic acid may increase the hypoglycemic activities of Pioglitazone.
PiroxicamThe risk or severity of adverse effects can be increased when Piroxicam is combined with Acetylsalicylic acid.
PralatrexateThe serum concentration of Pralatrexate can be increased when it is combined with Acetylsalicylic acid.
PramlintideAcetylsalicylic acid may increase the hypoglycemic activities of Pramlintide.
PrasugrelThe risk or severity of adverse effects can be increased when Prasugrel is combined with Acetylsalicylic acid.
PrednisoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Prednisolone.
PrednisoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Prednisone.
ProbenecidThe therapeutic efficacy of Probenecid can be decreased when used in combination with Acetylsalicylic acid.
ProcyclidineThe risk or severity of adverse effects can be increased when Procyclidine is combined with Acetylsalicylic acid.
QuinaprilAcetylsalicylic acid may decrease the antihypertensive activities of Quinapril.
QuinineAcetylsalicylic acid may increase the hypoglycemic activities of Quinine.
RamiprilAcetylsalicylic acid may decrease the antihypertensive activities of Ramipril.
RamosetronAcetylsalicylic acid may increase the activities of Ramosetron.
RepaglinideAcetylsalicylic acid may increase the hypoglycemic activities of Repaglinide.
Repository corticotropinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Repository corticotropin.
ReteplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Reteplase.
RidogrelAcetylsalicylic acid may increase the anticoagulant activities of Ridogrel.
RitodrineThe risk or severity of adverse effects can be increased when Ritodrine is combined with Acetylsalicylic acid.
RivaroxabanAcetylsalicylic acid may increase the anticoagulant activities of Rivaroxaban.
RosiglitazoneAcetylsalicylic acid may increase the hypoglycemic activities of Rosiglitazone.
SalmeterolThe risk or severity of adverse effects can be increased when Salmeterol is combined with Acetylsalicylic acid.
SalsalateAcetylsalicylic acid may increase the anticoagulant activities of Salsalate.
SaxagliptinAcetylsalicylic acid may increase the hypoglycemic activities of Saxagliptin.
SertralineSertraline may increase the antiplatelet activities of Acetylsalicylic acid.
SitagliptinAcetylsalicylic acid may increase the hypoglycemic activities of Sitagliptin.
SpironolactoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Spironolactone.
StreptokinaseAcetylsalicylic acid may increase the anticoagulant activities of Streptokinase.
SulfadiazineAcetylsalicylic acid may increase the hypoglycemic activities of Sulfadiazine.
SulfamethoxazoleAcetylsalicylic acid may increase the hypoglycemic activities of Sulfamethoxazole.
SulfisoxazoleAcetylsalicylic acid may increase the hypoglycemic activities of Sulfisoxazole.
SulindacThe risk or severity of adverse effects can be increased when Sulindac is combined with Acetylsalicylic acid.
SulodexideAcetylsalicylic acid may increase the anticoagulant activities of Sulodexide.
SunitinibAcetylsalicylic acid may increase the hypoglycemic activities of Sunitinib.
TalniflumateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Talniflumate.
TenecteplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tenecteplase.
TerbutalineThe risk or severity of adverse effects can be increased when Terbutaline is combined with Acetylsalicylic acid.
Tiaprofenic acidThe risk or severity of adverse effects can be increased when Tiaprofenic acid is combined with Acetylsalicylic acid.
TicagrelorAcetylsalicylic acid may increase the antiplatelet activities of Ticagrelor.
TiclopidineThe risk or severity of adverse effects can be increased when Ticlopidine is combined with Acetylsalicylic acid.
TicrynafenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ticrynafen.
TiludronateThe serum concentration of Tiludronate can be decreased when it is combined with Acetylsalicylic acid.
TinzaparinAcetylsalicylic acid may increase the anticoagulant activities of Tinzaparin.
TipranavirTipranavir may increase the antiplatelet activities of Acetylsalicylic acid.
TirofibanThe risk or severity of adverse effects can be increased when Tirofiban is combined with Acetylsalicylic acid.
TolazamideAcetylsalicylic acid may increase the hypoglycemic activities of Tolazamide.
TolbutamideAcetylsalicylic acid may increase the hypoglycemic activities of Tolbutamide.
TolmetinThe risk or severity of adverse effects can be increased when Tolmetin is combined with Acetylsalicylic acid.
TopiramateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Topiramate.
TorasemideAcetylsalicylic acid may decrease the diuretic activities of Torasemide.
TositumomabThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tositumomab.
TrandolaprilAcetylsalicylic acid may decrease the antihypertensive activities of Trandolapril.
TreprostinilThe risk or severity of adverse effects can be increased when Treprostinil is combined with Acetylsalicylic acid.
TriamcinoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Triamcinolone.
TriamtereneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Triamterene.
TrichlormethiazideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Trichlormethiazide.
TrimethoprimAcetylsalicylic acid may increase the hypoglycemic activities of Trimethoprim.
TrimipramineTrimipramine may increase the antiplatelet activities of Acetylsalicylic acid.
UrokinaseAcetylsalicylic acid may increase the anticoagulant activities of Urokinase.
Valproic AcidThe serum concentration of Valproic Acid can be increased when it is combined with Acetylsalicylic acid.
VenlafaxineVenlafaxine may increase the antiplatelet activities of Acetylsalicylic acid.
VerapamilVerapamil may increase the anticoagulant activities of Acetylsalicylic acid.
VilazodoneVilazodone may increase the antiplatelet activities of Acetylsalicylic acid.
Vitamin EVitamin E may increase the antiplatelet activities of Acetylsalicylic acid.
VorapaxarThe risk or severity of adverse effects can be increased when Vorapaxar is combined with Acetylsalicylic acid.
VortioxetineVortioxetine may increase the antiplatelet activities of Acetylsalicylic acid.
WarfarinAcetylsalicylic acid may increase the anticoagulant activities of Warfarin.
ZonisamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Zonisamide.
Food Interactions
  • Avoid alcohol, alcohol appears to cause a 50 to 100% increases in ASA serum levels.
  • Take with a full glass of water.
  • Take with food to reduce gastric irritation.

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Prostaglandin-endoperoxide synthase activity
Specific Function:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the gener...
Gene Name:
PTGS1
Uniprot ID:
P23219
Molecular Weight:
68685.82 Da
References
  1. Stevenson DD, Szczeklik A: Clinical and pathologic perspectives on aspirin sensitivity and asthma. J Allergy Clin Immunol. 2006 Oct;118(4):773-86; quiz 787-8. Epub 2006 Sep 1. [PubMed:17030227 ]
  2. Flipo RM: [Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?]. Presse Med. 2006 Sep;35(9 Spec No 1):1S53-60. [PubMed:17078596 ]
  3. Schwartz KA: Aspirin resistance: a review of diagnostic methodology, mechanisms, and clinical utility. Adv Clin Chem. 2006;42:81-110. [PubMed:17131625 ]
  4. Birnbaum Y, Ye Y, Lin Y, Freeberg SY, Huang MH, Perez-Polo JR, Uretsky BF: Aspirin augments 15-epi-lipoxin A4 production by lipopolysaccharide, but blocks the pioglitazone and atorvastatin induction of 15-epi-lipoxin A4 in the rat heart. Prostaglandins Other Lipid Mediat. 2007 Feb;83(1-2):89-98. Epub 2006 Nov 7. [PubMed:17259075 ]
  5. Guthikonda S, Lev EI, Patel R, DeLao T, Bergeron AL, Dong JF, Kleiman NS: Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. J Thromb Haemost. 2007 Mar;5(3):490-6. [PubMed:17319904 ]
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Prostaglandin-endoperoxide synthase activity
Specific Function:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, p...
Gene Name:
PTGS2
Uniprot ID:
P35354
Molecular Weight:
68995.625 Da
References
  1. Brzozowski T, Konturek PC, Sliwowski Z, Kwiecien S, Drozdowicz D, Pawlik M, Mach K, Konturek SJ, Pawlik WW: Interaction of nonsteroidal anti-inflammatory drugs (NSAID) with Helicobacter pylori in the stomach of humans and experimental animals. J Physiol Pharmacol. 2006 Sep;57 Suppl 3:67-79. [PubMed:17033106 ]
  2. Wang HJ, Liu XJ, Yang KX, Luo FM, Lou JY, Peng ZL: [Effects of nonsteroidal anti-inflammatory drug celecoxib on expression of cyclooxygenase-2 (COX-2) in ovarian carcinoma cell]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2006 Sep;37(5):757-60. [PubMed:17037745 ]
  3. Shen J, Gammon MD, Terry MB, Teitelbaum SL, Neugut AI, Santella RM: Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk. Breast Cancer Res. 2006;8(6):R71. [PubMed:17181859 ]
  4. Nakano M, Denda N, Matsumoto M, Kawamura M, Kawakubo Y, Hatanaka K, Hiramoto Y, Sato Y, Noshiro M, Harada Y: Interaction between cyclooxygenase (COX)-1- and COX-2-products modulates COX-2 expression in the late phase of acute inflammation. Eur J Pharmacol. 2007 Mar 22;559(2-3):210-8. Epub 2006 Dec 16. [PubMed:17258197 ]
  5. Hall MN, Campos H, Li H, Sesso HD, Stampfer MJ, Willett WC, Ma J: Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):314-21. [PubMed:17301265 ]
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Specific Function:
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Gene Name:
AKR1C1
Uniprot ID:
Q04828
Molecular Weight:
36788.02 Da
References
  1. Dhagat U, Carbone V, Chung RP, Matsunaga T, Endo S, Hara A, El-Kabbani O: A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase. Med Chem. 2007 Nov;3(6):546-50. [PubMed:18045204 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
activator
General Function:
Tau-protein kinase activity
Specific Function:
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts ...
Gene Name:
PRKAA1
Uniprot ID:
Q13131
Molecular Weight:
64008.64 Da
References
  1. Din FV, Valanciute A, Houde VP, Zibrova D, Green KA, Sakamoto K, Alessi DR, Dunlop MG: Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells. Gastroenterology. 2012 Jun;142(7):1504-15.e3. doi: 10.1053/j.gastro.2012.02.050. Epub 2012 Mar 6. [PubMed:22406476 ]
  2. Hawley SA, Fullerton MD, Ross FA, Schertzer JD, Chevtzoff C, Walker KJ, Peggie MW, Zibrova D, Green KA, Mustard KJ, Kemp BE, Sakamoto K, Steinberg GR, Hardie DG: The ancient drug salicylate directly activates AMP-activated protein kinase. Science. 2012 May 18;336(6083):918-22. doi: 10.1126/science.1215327. Epub 2012 Apr 19. [PubMed:22517326 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Phosphatidylinositol phospholipase c activity
Specific Function:
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Gene Name:
EDNRA
Uniprot ID:
P25101
Molecular Weight:
48721.76 Da
References
  1. Talbodec A, Berkane N, Blandin V, Breittmayer JP, Ferrari E, Frelin C, Vigne P: Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism. Mol Pharmacol. 2000 Apr;57(4):797-804. [PubMed:10727528 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Scaffold protein binding
Specific Function:
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These mo...
Gene Name:
IKBKB
Uniprot ID:
O14920
Molecular Weight:
86563.245 Da
References
  1. Yin MJ, Yamamoto Y, Gaynor RB: The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998 Nov 5;396(6706):77-80. [PubMed:9817203 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
acetylation
General Function:
Not Available
Specific Function:
Not Available
Gene Name:
TP53
Uniprot ID:
P04637
Molecular Weight:
43652.79 Da
References
  1. Alfonso LF, Srivenugopal KS, Bhat GJ: Does aspirin acetylate multiple cellular proteins? (Review). Mol Med Rep. 2009 Jul-Aug;2(4):533-7. doi: 10.3892/mmr_00000132. [PubMed:21475861 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
binding
General Function:
Unfolded protein binding
Specific Function:
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
Gene Name:
HSPA5
Uniprot ID:
P11021
Molecular Weight:
72332.425 Da
References
  1. Deng WG, Ruan KH, Du M, Saunders MA, Wu KK: Aspirin and salicylate bind to immunoglobulin heavy chain binding protein (BiP) and inhibit its ATPase activity in human fibroblasts. FASEB J. 2001 Nov;15(13):2463-70. [PubMed:11689471 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Ribosomal protein s6 kinase activity
Specific Function:
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apopto...
Gene Name:
RPS6KA3
Uniprot ID:
P51812
Molecular Weight:
83735.325 Da
References
  1. Stevenson MA, Zhao MJ, Asea A, Coleman CN, Calderwood SK: Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes. J Immunol. 1999 Nov 15;163(10):5608-16. [PubMed:10553090 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Ubiquitin protein ligase binding
Specific Function:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Gene Name:
NFKBIA
Uniprot ID:
P25963
Molecular Weight:
35608.65 Da
References
  1. Stevenson MA, Zhao MJ, Asea A, Coleman CN, Calderwood SK: Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes. J Immunol. 1999 Nov 15;163(10):5608-16. [PubMed:10553090 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
antagonist
General Function:
Transcriptional activator activity, rna polymerase ii core promoter proximal region sequence-specific binding
Specific Function:
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-co...
Gene Name:
NFKB2
Uniprot ID:
Q00653
Molecular Weight:
96748.355 Da
References
  1. Kopp E, Ghosh S: Inhibition of NF-kappa B by sodium salicylate and aspirin. Science. 1994 Aug 12;265(5174):956-9. [PubMed:8052854 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inducer
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Gene Name:
CYP2C19
Uniprot ID:
P33261
Molecular Weight:
55930.545 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme...
Gene Name:
CYP2C8
Uniprot ID:
P10632
Molecular Weight:
55824.275 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenyto...
Gene Name:
CYP2C9
Uniprot ID:
P11712
Molecular Weight:
55627.365 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]

Carriers

Kind
Protein
Organism
Human
Pharmacological action
no
Actions
other/unknown
General Function:
Toxic substance binding
Specific Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Gene Name:
ALB
Uniprot ID:
P02768
Molecular Weight:
69365.94 Da
References
  1. Sulkowska A, Bojko B, Rownicka J, Sulkowski WW: Competition of cytarabine and aspirin in binding to serum albumin in multidrug therapy. Biopolymers. 2006 Apr 15;81(6):464-72. [PubMed:16419075 ]
  2. Dundee JW, Halliday NJ, McMurray TJ: Aspirin and probenecid pretreatment influences the potency of thiopentone and the onset of action of midazolam. Eur J Anaesthesiol. 1986 May;3(3):247-51. [PubMed:3780693 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-in...
Gene Name:
SLC22A6
Uniprot ID:
Q4U2R8
Molecular Weight:
61815.78 Da
References
  1. Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. [PubMed:10220563 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Xenobiotic-transporting atpase activity
Specific Function:
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Gene Name:
ABCB1
Uniprot ID:
P08183
Molecular Weight:
141477.255 Da
References
  1. Faassen F, Vogel G, Spanings H, Vromans H: Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. Int J Pharm. 2003 Sep 16;263(1-2):113-22. [PubMed:12954186 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.
Gene Name:
SLC22A7
Uniprot ID:
Q9Y694
Molecular Weight:
60025.025 Da
References
  1. Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H: Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett. 1998 Jun 12;429(2):179-82. [PubMed:9650585 ]
Comments
comments powered by Disqus
Drug created on June 13, 2005 07:24 / Updated on May 05, 2016 02:30