Otitis externa bacterial

Also known as: Acute otitis externa caused by Pseudomonas aeruginosa / Acute otittis externa caused by pseudomonas aeruginosa / Otitis externa caused by bacteria (disorder)

Drugs
Drugs and Targets

Drug	Drug Name	Drug Description
DB00537	Ciprofloxacin	A second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB09552	Thonzonium	A cationic surfactant used to disperse exudate and cellular debris, as well as enhance the penetration of antimicrobials.

Drug	Drug Name	Target	Type
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 2-alpha	target
DB00537	Ciprofloxacin	Cytochrome P450 1A2	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A4	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A5	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A7	enzyme
DB00537	Ciprofloxacin	P-glycoprotein 1	transporter
DB00537	Ciprofloxacin	Potassium voltage-gated channel subfamily H member 2	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit B	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	Multidrug resistance protein MdtK	target
DB00537	Ciprofloxacin	Gyrase A	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	Multidrug and toxin extrusion protein 1	transporter
DB00537	Ciprofloxacin	Multidrug and toxin extrusion protein 2	transporter
DB00537	Ciprofloxacin	Serum albumin	carrier
DB09552	Thonzonium	V-type proton ATPase subunit C 1	target

Drug	Drug Name	Phase	Status	Count