Phenformin hydrochlorideProduct ingredient for Phenformin
- Name
- Phenformin hydrochloride
- Drug Entry
- Phenformin
A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
- Accession Number
- DBSALT000273
- Structure
Structure for Phenformin hydrochloride (DBSALT000273)
- Synonyms
- Phenformin HCl
- UNII
- 91XC93EU03
- CAS Number
- 834-28-6
- Weight
- Average: 241.721
Monoisotopic: 241.109423244 - Chemical Formula
- C10H16ClN5
- InChI Key
- YSUCWSWKRIOILX-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H
- IUPAC Name
- 1-carbamimidamido-N-(2-phenylethyl)methanimidamide hydrochloride
- SMILES
- Cl.NC(=N)NC(=N)NCCC1=CC=CC=C1
- External Links
- PubChem Compound
- 13266
- ChemSpider
- 12708
- ChEMBL
- CHEMBL1528839
- Predicted Properties
Property Value Source Water Solubility 0.232 mg/mL ALOGPS logP -0.72 ALOGPS logP 0.83 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 19.18 Chemaxon pKa (Strongest Basic) 11.97 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 97.78 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 80.72 m3·mol-1 Chemaxon Polarizability 22.14 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon