Fencamfamine hydrochlorideProduct ingredient for Fencamfamin

Name
Fencamfamine hydrochloride
Drug Entry
Fencamfamin

Fencamfamin (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Fencamfamin is used for treating depressive day-time fatigue, lack of concentration and lethargy. It is especially useful in patients with chronic conditions due to its favourable safety profile.

Accession Number
DBSALT000814
Structure
Synonyms
Fencamfamine HCl
UNII
0M1J60BWEX
CAS Number
2240-14-4
Weight
Average: 251.795
Monoisotopic: 251.144077416
Chemical Formula
C15H22ClN
InChI Key
CVFSMSTXULJISA-UHFFFAOYSA-N
InChI
InChI=1S/C15H21N.ClH/c1-2-16-15-13-9-8-12(10-13)14(15)11-6-4-3-5-7-11;/h3-7,12-16H,2,8-10H2,1H3;1H
IUPAC Name
N-ethyl-3-phenylbicyclo[2.2.1]heptan-2-amine hydrochloride
SMILES
Cl.CCNC1C2CCC(C2)C1C1=CC=CC=C1
PubChem Compound
102773
ChemSpider
92834
ChEMBL
CHEMBL2106270
Predicted Properties
PropertyValueSource
Water Solubility0.00295 mg/mLALOGPS
logP3.46ALOGPS
logP3.21Chemaxon
logS-4.9ALOGPS
pKa (Strongest Basic)10.56Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area12.03 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity67.64 m3·mol-1Chemaxon
Polarizability26.13 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon