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Displaying drugs 401 - 419 of 419 in total
Golvatinib
Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.
Investigational
Matched Description: … Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and …
UK-432097
UK-432,097 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Tandutinib
MLN518 is a novel, oral, small molecule designed to inhibit type III receptor tyrosine kinases, including FLT3, (platelet-derived growth-factor receptor) PDGFR and c-KIT. Tyrosine kinases are enzymes involved in several cellular processes and are known to be activated in cancer cells to drive tumor growth. AML patients with FLT3 mutations...
Investigational
Matched Description: … Food and Drug Administration. Phase I/II trials are underway. ... type III receptor tyrosine kinases, including FLT3, (platelet-derived growth-factor receptor) PDGFR and ... Tyrosine kinases are enzymes involved in several cellular processes and are known to be activated in …
3'-1-carboxy-1-phosphonooxy-ethoxy-uridine-diphosphate-N-acetylglucosamine
Experimental
Matched Iupac: … hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-2-(phosphonooxy)propanoic acid …
Ozarelix
Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy, and Benign Prostatic Hyperplasia (BPH).
Investigational
Matched Description: … Ozarelix has been used in trials studying the treatment of Prostate Cancer, Benign Prostatic Hypertrophy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine-D-Glutamate
Experimental
Matched Iupac: … phosphoryl}oxy)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}propanamido]propanamido]pentanedioic acid …
Nikkomycin Z
Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis.
Investigational
Matched Iupac: … methylbutanamido]-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid …
Matched Description: … Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis. …
Matched Description: … Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis. …
Olcegepant
Boehringer Ingelheim Pharmaceuticals’ olcegepant (BIBN 4096) is a selective Calcitonin Gene-Related Peptide (CGRP) antagonist, a new class of drugs in development for the treatment of acute migraine attacks. Olcegepant is undergoing phase II trials in Europe and the US, with preliminary results suggesting that CGRP antagonists may represent a potential...
Investigational
Matched Description: … Olcegepant is undergoing phase II trials in Europe and the US, with preliminary results suggesting that …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
P1-(adenosine-5'-P5-(uridine-5')pentaphosphate
Experimental
Matched Iupac: … tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphinic acid …
p1-(5'-adenosyl)p5-(5'-thymidyl)pentaphosphate
Experimental
Matched Iupac: … dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy})phosphinic acid …
Thymectacin
Thymectacin, a phosphoramidate derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine, is a novel small molecule anticancer agent. Thymectacin is selectively active against tumor cells expressing high levels of thymidylate synthase (TS), a critical enzyme in DNA biosynthesis. Thymectacin was as efficacious as irinotecan, a drug recently approved for the treatment of 5-fluorouracil-resistant colon cancer.
Investigational
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Chymostatin
Experimental
Matched Iupac: … (2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl}butyl]carbamoyl})methyl]carbamoyl}amino)-3-phenylpropanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Adenylate-3'-phosphate-[[2'-deoxy-uridine-5'-phosphate]-3'-phosphate]
Experimental
Matched Iupac: … -yl]oxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid …
Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine
Experimental
Matched Iupac: … (hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}propanamido]propanoic acid …
Displaying drugs 401 - 419 of 419 in total