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Displaying drugs 8401 - 8425 of 10507 in total
AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3. AMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis).
Investigational
Matched Iupac: … }-25-(2-carbamoylethyl)-10-[(1H-imidazol-5-yl)methyl]-19-[(1H-indol-3-yl)methyl]-13,17-dimethyl-28-[( ... 2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-34-[(2S,3S)-2-[(2R)-2-amino-3-(4-hydroxyphenyl)propanamido ... ]-3-methylpentanamido]-7-(3-carbamimidamidopropyl)-4-{[(1S,2S)-1-carbamoyl-2-methylbutyl](methyl)carbamoyl …
Experimental
Matched Iupac: … 5-[(2-methoxyphenoxy)methyl]-1,3-oxazolidin-2-one …
Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors. Merck has...
Investigational
Matched Iupac: … (7S)-5-methyl-2,5,19-triazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(15),8,10,12,16,18-hexaene …
Matched Description: … This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors …
Matched Salts cas: … 680993-85-5 ... 1448014-35-4
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT3 Receptor Antagonists …
Experimental
Matched Synonyms: … (S)-5-amino-5-carboxy-N,N,N-trimethyl-1-pentanaminium …
Matched Iupac: … [(5S)-5-amino-5-carboxypentyl]trimethylazanium …
Experimental
Matched Iupac: … (2S,3S,4S,5S,6R)-6-({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan …
Experimental
Matched Iupac: … (5R,9R,12aS,13S,15S,15aS,16S,18aS)-16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H, …
Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.
Experimental
Matched Iupac: … -2-yl]oxy}-3-ethyl-2,10-dihydroxy-7-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-15 ... (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-9-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan ... -[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one …
Experimental
Matched Name: … [{(5-Chloro-2-Pyridinyl)Amino} Methylene]-1,1-Bisphosphonate …
Matched Iupac: … {[(5-chloropyridin-2-yl)amino](phosphono)methyl}phosphonic acid …
MDI-P has demonstrated potent anti-HIV activity. MDI-P has been shown to be effective in killing HIV in cell culture. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). MDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF").
Investigational
Matched Iupac: … [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](propan-2-yl)amine …
Motuporin is a toxin isolated from the marine sponge Thenonella swinhoie grey.
Experimental
Matched Iupac: … (2Z,5R,6S,9S,12S,13S,16R)-2-ethylidene-12-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien …
Experimental
Matched Name: … Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone Hydrate …
Experimental
Matched Name: … N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpentanedioic …
Experimental
An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. [PubChem]
Experimental
Illicit
Matched Iupac: … 1-(2H-1,3-benzodioxol-5-yl)propan-2-amine …
NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life, stability, and oral bioavailability. It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and...
Investigational
Experimental
Matched Iupac: … (2R)-2-amino-3-[(R)-sulfino]propanoic acid …
L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate. It occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather.
Experimental
Prunus armeniaca seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Withdrawn from the Canadian, US, and UK markets in 1963 due to nephropathy.
Withdrawn
Displaying drugs 8401 - 8425 of 10507 in total