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Displaying drugs 101 - 125 of 2576 in total

Esomeprazole

Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... Esomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid ... be expressed in order to resume acid secretion, esomeprazole's duration of antisecretory effect persists …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer …
Matched Products: … Foster and Thrive Acid Reducer ... Acid Reducer ... Harris Teeter Acid Reducer …

Tiludronic acid

Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Synonyms: … Acide tiludronique ... Acido tiludronico ... Tiludronic acid …
Matched Name: … Tiludronic acid …
Matched Iupac: … {[(4-chlorophenyl)sulfanyl](phosphono)methyl}phosphonic acid …
Matched Description: … ] and [clodronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... [A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763] …
Matched Categories: … tiludronic acid ... Drugs Affecting Bone Structure and Mineralization …

Niflumic acid

Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Experimental
Matched Synonyms: … Acide niflumique ... Acido niflumico ... Niflumic acid …
Matched Name: … Niflumic acid …
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid …
Matched Description: … Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis …
Matched Categories: … Niflumic Acid and Prodrugs ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic …

Iotroxic acid

Iotroxic acid is a contrast medium molecule.
Experimental
Withdrawn
Matched Synonyms: … Acide iotroxique ... Acido iotroxico ... Iotroxic acid …
Matched Name: … Iotroxic acid …
Matched Iupac: … (2-{[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]methoxy}ethoxy)ethoxy]acetamido}-2,4,6-triiodobenzoic acid …
Matched Description: … Iotroxic acid is a contrast medium molecule. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... iotroxic acid ... Triiodobenzoic Acids …

Pamidronic acid

Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Synonyms: … Acide pamidronique ... Acido pamidronico ... Pamidronic acid …
Matched Name: … Pamidronic acid …
Matched Iupac: … (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid …
Matched Description: … ] and [alendronic acid]. ... ], [zoledronic acid], [minodronic acid], and [risedronic acid] are becoming more popular. ... Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid …
Matched Categories: … pamidronic acid ... Drugs Affecting Bone Structure and Mineralization …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alcohols …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … amino acid, 170 kDa protein [FDA Label]. ... purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Synonyms: … Acide risédroniqe ... Acido risedronico ... Risedronic acid …
Matched Name: … Risedronic acid …
Matched Iupac: … [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid …
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of …
Matched Categories: … risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential ... risedronic acid ... Calcium-Regulating Hormones and Agents …

Lonoctocog alfa

Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA 250IU powder and solvent for solution for injection …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … are D-amino acids. ... derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Synonyms: … cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L …
Matched Iupac: … (3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

Betulin

Investigational
Matched Synonyms: … Betulinic alcohol …

Sulfuric acid

Experimental
Matched Synonyms: … Acide sulfurique ... Acido sulfurico ... Brimstone acid …
Matched Name: … Sulfuric acid …
Matched Iupac: … sulfuric acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …

Butyl alcohol

Experimental
Matched Synonyms: … N-butyl alcohol …
Matched Name: … Butyl alcohol …
Matched Categories: … Alcohols ... Fatty Alcohols …

Caprylic alcohol

Caprylic alcohol has been used in trials studying the treatment of Essential Tremor.
Investigational
Matched Name: … Caprylic alcohol …
Matched Description: … Caprylic alcohol has been used in trials studying the treatment of Essential Tremor. …
Matched Categories: … Alcohols ... Fatty Alcohols …

Cinnamyl alcohol

Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as DB14184 within commercial products. Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% . Sensitivity...
Approved
Experimental
Matched Synonyms: … Cinnamyl alcohol ... (E)-cinnamyl alcohol …
Matched Name: … Cinnamyl alcohol …
Matched Description: … Cinnamyl alcohol is a naturally occurring compound that is found within cinnamon. ... Sensitivity to cinnamyl alcohol may be identified with a clinical patch test. ... Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266 …
Matched Categories: … Alcohols …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Synonyms: … Acide gadobenique ... Acido gadobenico ... Gadobenic acid …
Matched Name: … Gadobenic acid …
Matched Description: … Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and …
Matched Categories: … gadobenic acid ... Alcohols ... Sugar Alcohols …

Aluminum acetate

Approved
Investigational
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Products: … ACID MANTLECREMA ... ACID MANTLE NLOCION ... ACID MANTLE N LOCION …

Romilkimab

Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … A and D Diaper Rash and Skin Protectant ... PETROLATUM and LANOLIN ... Up and Up Diaper Rash …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Procurevitamin A and D Vitamin A and D ... A and D ... Vitamin A and D …
Displaying drugs 101 - 125 of 2576 in total