Displaying drugs 13126 - 13150 of 13236 in total
Tianeptine
Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants .
Tianeptine was discovered and...
Investigational
Matched Iupac: … 7-({6-chloro-10-methyl-9,9-dioxo-9lambda6-thia-10-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 ... -hexaen-2-yl}amino)heptanoic acid …
Matched Description: … Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological …
Matched Salts cas: … 30123-17-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied ... Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological …
Matched Salts cas: … 30123-17-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
ZY19489
Investigational
Matched Iupac: … N2-(4-cyclopropyl-5-fluoro-6-methylpyridin-2-yl)-N4-(1,5-dimethyl-1H-pyrazol-3-yl)-5-[(3R)-3,4-dimethylpiperazin ... -1-yl]pyrimidine-2,4-diamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lancovutide
Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is closely related to cinnamycin (Ro09-0198). It belongs to the lantibiotics. Lantibiotics are bacteriocins that are characterized by the presence of a high proportion of...
Investigational
Matched Iupac: … nonadecaazapentacyclo[38.18.9.3^{19,56}.3^{28,53}.0^{9,13}]triheptacontane-65-carboxylic acid ... 22S,25S,28R,31S,37S,40S,41S,44R,47S,50S,53S,56R,65S,70S)-44-amino-47-(4-aminobutyl)-4,16,22-tribenzyl-50 ... -octadecaoxo-25-(propan-2-yl)-42,69,72-trithia-3,6,9,15,18,21,24,27,30,33,36,39,46,49,52,55,58,60,66- ... -(2-carbamoylethyl)-37-(carbamoylmethyl)-31-[(R)-carboxy(hydroxy)methyl]-41,70-dimethyl-2,5,8,14,17,20,23,26,29,32,35,38,45,48,51,54,57,67 …
Matched Description: … Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. ... Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is ... Lantibiotics are bacteriocins that are characterized by the presence of a high proportion of unusual …
Matched Description: … Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis. ... Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is ... Lantibiotics are bacteriocins that are characterized by the presence of a high proportion of unusual …
Virginiamycin
Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent microbial contamination and in livestock to prevent and treat infections. According to a USDA study, antibiotics can save as much...
Vet approved
Matched Iupac: … [23.2.1.0^{3,7}]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone; N-[(3S,6S,12R,15S,16R,19S ... [20.4.0.0^{6,10}]hexacosan-15-yl]-3-hydroxypyridine-2-carboxamide ... (10R,11R,12E,17E,19E,21S)-21-hydroxy-11,19-dimethyl-10-(propan-2-yl)-9,26-dioxa-3,15,28-triazatricyclo ... ,22S)-3-benzyl-12-ethyl-4,16-dimethyl-2,5,11,14,18,21,24-heptaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentaazatricyclo …
Matched Description: … It is a combination of pristinamycin IIA and virginiamycin S1. ... Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. ... According to a USDA study, antibiotics can save as much as 30% in feed costs among young swine. …
Matched Description: … It is a combination of pristinamycin IIA and virginiamycin S1. ... Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. ... According to a USDA study, antibiotics can save as much as 30% in feed costs among young swine. …
Pantoyl Adenylate
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[(2R)-2,4-dihydroxy-3,3- …
3'-phospho-5'-adenylyl sulfate
3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process...
Experimental
Matched Synonyms: … 3'-phosphoadenylyl sulfate ... 3'-phosphoadenosine 5'-phosphosulfate …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … 3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters ... It is formed from sulfate ion and ATP in a two-step process. …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … 3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters ... It is formed from sulfate ion and ATP in a two-step process. …
Uridine 5'-triphosphate
Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
Experimental
Investigational
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}( …
Matched Description: … A uracil nucleotide containing three phosphate groups esterified to the sugar moiety. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … A uracil nucleotide containing three phosphate groups esterified to the sugar moiety. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Phosphoaminophosphonic Acid-Adenylate Ester
5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]
Experimental
Matched Iupac: … ({[({[(2S,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Description: … An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a ... It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits …
Matched Description: … An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a ... It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits …
Sulprostone
Sulprostone has been used in trials studying Abortion, Induced.
Investigational
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl]-N-methanesulfonylhept …
SB-1578
SB-1578 is under investigation in clinical trial NCT01235871 (A Single and Multiple-Dose Study of SB1578).
Investigational
Matched Iupac: … (9E)-15-[2-(pyrrolidin-1-yl)ethoxy]-7,12,26-trioxa-19,21,24-triazatetracyclo[18.3.1.1^{2,5}.1^{14,18} ... ]hexacosa-1(23),2,4,9,14,16,18(25),20(24),21-nonaene …
Matched Description: … SB-1578 is under investigation in clinical trial NCT01235871 (A Single and Multiple-Dose Study of SB1578 …
Matched Categories: … fms-Like Tyrosine Kinase 3, antagonists & inhibitors …
Matched Description: … SB-1578 is under investigation in clinical trial NCT01235871 (A Single and Multiple-Dose Study of SB1578 …
Matched Categories: … fms-Like Tyrosine Kinase 3, antagonists & inhibitors …
Glucosaminyl-(Alpha-6)-D-Myo-Inositol
Experimental
Matched Iupac: … (1R,2R,3R,4R,5S,6R)-6-{[(2R,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}cyclohexane …
KD3010
KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for the treatment of metabolic disorders, including obesity.
Investigational
Matched Iupac: … ]sulfonyl}-2,3-dihydro-1H-indene-2-carboxylic acid ... 4-methylbenzene-1-sulfonic acid; 4-{[(2R,6S)-2,6-dimethyl-4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl …
Matched Description: … KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … KD3010 is a small molecule peroxisome proliferator-activator receptor delta (PPAR Delta) agonist for …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MK-0812
MK0812 has been used in trials studying the treatment of Relapsing-Remitting Multiple Sclerosis.
Investigational
Matched Iupac: … (3S,4S)-3-methoxy-N-[(1R,3S)-3-(propan-2-yl)-3-{[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridin …
Fluprostenol
Vet approved
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl]cyclopentyl …
Matched Salts cas: … 55028-71-2 …
Matched Salts cas: … 55028-71-2 …
Modufolin
Modufolin is under investigation for the treatment of Osteosarcoma.
Investigational
Matched Iupac: … (2S)-2-({4-[(6aR)-3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}formamido …
GDC-0349
GDC-0349 has been used in trials studying the treatment of Non-Hodgkin's Lymphoma, Solid Tumor.
Investigational
Matched Iupac: … 3-ethyl-1-(4-{4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-2-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fluperolone
Experimental
Matched Iupac: … (1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-[(2S)-2-hydroxypropanoyl]-2,15-dimethyltetracyclo …
Temsavir
Investigational
Matched Iupac: … 1-(4-benzoylpiperazin-1-yl)-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin- ... 3-yl]ethane-1,2-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Zinc Substituted Heme C
Experimental
Matched Iupac: … lambda4-zinc(4+) (20E)-10,14-bis(2-carboxyethyl)-5,20-diethylidene-4,9,15,19-tetramethyl-21,22,23,24- ... tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3,6,8,10,12,14,16,18-nonaene-21,22,23,24 …
Lupeol
Lupeol has been investigated for the treatment of Acne.
Investigational
Matched Iupac: … (1R,2R,5R,8R,9R,10R,13R,14R,17S,19R)-1,2,5,14,18,18-hexamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹ …
Prednylidene
Prednylidene is an experimental systemic glucocorticoid.
Experimental
Matched Iupac: … (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyl-13-methylidenetetracyclo …
Cloprednol
Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma. [A31775,A31776]
Experimental
Matched Iupac: … (1S,2R,10S,11S,14R,15S,17S)-8-chloro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0 …
Matched Description: … Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma …
Matched Description: … Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma …
Valinomycin
A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used...
Experimental
Matched Iupac: … 6S,9R,12R,15S,18S,21R,24R,27S,30S,33R,36R)-6,18,30-trimethyl-3,9,12,15,21,24,27,33,36-nonakis(propan-2- …
Matched Description: … It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid ... (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a ... linked alternately to form a 36-membered ring. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid ... (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a ... linked alternately to form a 36-membered ring. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Aspartyl-Adenosine-5'-Monophosphate
Experimental
Matched Iupac: … (3S)-3-amino-4-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy) …
Glycocholic acid
The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
Experimental
Investigational
Matched Synonyms: … N-choloylglycine …
Matched Iupac: … 2-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7 …
Matched Description: … It acts as a detergent to solubilize fats for absorption and is itself absorbed. …
Matched Categories: … N-substituted Glycines ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … 2-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7 …
Matched Description: … It acts as a detergent to solubilize fats for absorption and is itself absorbed. …
Matched Categories: … N-substituted Glycines ... Compounds used in a research, industrial, or household setting …
Displaying drugs 13126 - 13150 of 13236 in total