Ammonium carbonate
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Ammonium carbonate is an expectorant indicated to treat a cough and phlegm.
- Generic Name
- Ammonium carbonate
- DrugBank Accession Number
- DB15926
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
- Weight
- Average: 96.086
Monoisotopic: 96.053492126 - Chemical Formula
- CH8N2O3
- Synonyms
- Carbonic acid, diammonium salt
- Crystal ammonia
- Diammonium carbonate
- External IDs
- 208-058-0
- E 503(I)
- E-503(I)
- INS 503(I)
- INS-503(I)
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination for symptomatic treatment of Coughing Combination Product in combination with: Glycyrrhiza glabra (DB14312) ••• ••• •••••••• Used in combination for therapy Excess mucus or phlegm Combination Product in combination with: Glycyrrhiza glabra (DB14312) ••• ••• •••••••• - Associated Therapies
- Contraindications & Blackbox Warnings
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Bronchozone Cough Syrup Certified Ammonium carbonate (30 mg / mL) + Ammonium chloride (42 mg / mL) + Glycyrrhiza glabra (0.012 mL / mL) + Levomenthol (0.31 mg / mL) + Polygala senega root (0.015 mL / mL) Syrup Oral D.C. Labs Limited 1951-12-31 2003-07-11 Canada Esprit D'ammoniaque Aromatique Ammonium carbonate (4 g / 100 mL) + Ammonia (1.9 g / 100 mL) Liquid Nasal; Respiratory (inhalation) Lab Valmo EnregistrÉ, Division Of Technilab Inc. 1991-12-31 1996-09-09 Canada ยาแก้ไอขับเสมหะผสมชะเอม Ammonium carbonate (20 MG/5ML) + Glycyrrhiza glabra (0.25 ML/5ML) Solution องค์การเภสัชกรรม 2012-08-07 Not applicable Thailand
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- PDP691CN28
- CAS number
- 506-87-6
- InChI Key
- PRKQVKDSMLBJBJ-UHFFFAOYSA-N
- InChI
- InChI=1S/CH2O3.2H3N/c2-1(3)4;;/h(H2,2,3,4);2*1H3
- IUPAC Name
- diammonium carbonate
- SMILES
- [NH4+].[NH4+].[O-]C([O-])=O
References
- General References
- FDA Thailand: AMMONIUM CARBONATE AND GLYCYRRHIZA MIXTURE, oral solution [Link]
- External Links
- ChemSpider
- 10048
- 1310190
- ChEMBL
- CHEMBL2105849
- Wikipedia
- Ammonium_carbonate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Syrup Oral Liquid Nasal; Respiratory (inhalation) Solution - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 756.0 mg/mL ALOGPS logP -0.53 ALOGPS logP 0.25 Chemaxon logS 0.9 ALOGPS pKa (Strongest Acidic) 3.5 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 63.19 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 31.17 m3·mol-1 Chemaxon Polarizability 3.52 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 98.20793 predictedDeepCCS 1.0 (2019) [M+H]+ 101.00058 predictedDeepCCS 1.0 (2019) [M+Na]+ 109.81909 predictedDeepCCS 1.0 (2019)
Drug created at November 24, 2020 14:27 / Updated at May 07, 2021 21:08