Protein Precursors

DrugDrug NameDrug Description
DB00040GlucagonA form of recombinant glucagon used to treat hypoglycemia in diabetes mellitus and as a part of gastrointestinal imaging procedures.
DB00071Insulin porkA purified form of porcine insulin used to control hyperglycemia in diabetes mellitus.
DB01284TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
DB01285CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
DB05115NN344Investigated for use/treatment in diabetes mellitus type 1 and 2.
DB05819NBI-6024Investigated for use/treatment in diabetes mellitus type 1 and pediatric indications.
DB06655LiraglutideA GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes.
DB08900TeduglutideA glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support.
DB09043AlbiglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
DB09045DulaglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
DB09222Fibrinogen humanA hemostatic agent used for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
DB11653BremelanotideBremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of...
DB11700SetmelanotideSetmelanotide has been investigated for the treatment of obesity.
DB13298AlsactideNot Annotated
DB14027TaspoglutideTaspoglutide is a pharmaceutical drug, a glucagon-like peptide-1 agonist (GLP-1 agonist), under investigation for treatment of type 2 diabetes being codeveloped by Ipsen and Roche. In September 2010 Roche halted...
DB05433rGLP-1Investigated for use/treatment in congestive heart failure and diabetes mellitus type 2.
DB14812ProcalcitoninProcalcitonin is under investigation in clinical trial NCT03440060 (Procalcitonin-guided Antibiotic Therapy During Severe Exacerbation of COPD).
DB15158BPI-3016BPI-3016 is under investigation in clinical trial NCT03188848 (Dose Escalating Study of BPI-3016 in Healthy Subjects).
DrugDrug NameTargetType
DB00040GlucagonGlucagon receptortarget
DB00040GlucagonGlucagon-like peptide 2 receptortarget
DB00040GlucagonGlucagon-like peptide 1 receptortarget
DB00071Insulin porkInsulin receptortarget
DB00071Insulin porkHLA class II histocompatibility antigen, DQ alpha 2 chaintarget
DB00071Insulin porkHLA class II histocompatibility antigen, DQ beta 1 chaintarget
DB00071Insulin porkRetinoblastoma-associated proteintarget
DB00071Insulin porkCathepsin Dtarget
DB00071Insulin porkInsulin-like growth factor 1 receptortarget
DB00071Insulin porkInsulin-degrading enzymetarget
DB00071Insulin porkNeuroendocrine convertase 2target
DB00071Insulin porkCarboxypeptidase Etarget
DB00071Insulin porkNeuroendocrine convertase 1target
DB00071Insulin porkProtein NOV homologtarget
DB00071Insulin porkLow-density lipoprotein receptor-related protein 2target
DB00071Insulin porkInsulin-like growth factor-binding protein 7target
DB00071Insulin porkSynaptotagmin-like protein 4target
DB00071Insulin porkCytochrome P450 1A2enzyme
DB01284TetracosactideAdrenocorticotropic hormone receptortarget
DB01285CorticotropinAdrenocorticotropic hormone receptortarget
DB01285CorticotropinCorticoliberintarget
DB01285Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB01285Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB01285Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB01285CorticotropinCytochrome P450 3A4enzyme
DB05115NN344Insulin receptortarget
DB05115NN344Cytochrome P450 1A2enzyme
DB06655LiraglutideGlucagon-like peptide 1 receptortarget
DB06655LiraglutideDipeptidyl peptidase 4enzyme
DB06655LiraglutideNeprilysinenzyme
DB06655LiraglutideSerum albumincarrier
DB08900TeduglutideGlucagon-like peptide 2 receptortarget
DB09043AlbiglutideGlucagon-like peptide 1 receptortarget
DB09045DulaglutideGlucagon-like peptide 1 receptortarget
DB11653BremelanotideMelanocyte-stimulating hormone receptortarget
DB11653BremelanotideMelanocortin receptor 4target
DB11653BremelanotideMelanocortin receptor 3target
DB11653BremelanotideMelanocortin receptor 5target
DB11653BremelanotideAdrenocorticotropic hormone receptortarget