Benzyl Compounds

Benzene derivatives that contain a benzyl group with the general formula Phenyl-CH2-R.
DrugDrug NameDrug Description
DB00179MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
DB00773EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
DB01091ButenafineA topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis.
DB01179PodofiloxA topical agent used for the treatment of external genital warts and perianal warts.
DB01626PargylineFor the treatment of moderate to severe hypertension.
DB017112,3,4,5,6-Pentafluorobenzyl AlcoholNot Available
DB02464BenzylamineNot Available
DB02822Para-Bromobenzyl AlcoholNot Available
DB030582-Aminobenzyl alcoholNot Available
DB04200MatairesinolNot Available
DB04884DapoxetineFor the treatment of premature ejaculation.
DB04898XimelagatranFor the treatment of acute deep vein thrombosis.
DB06654SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
DB06770Benzyl alcoholAn antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
DB09082VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
DB11957IdalopirdineIdalopirdine has been used in trials studying the treatment of Cognition, Schizophrenia, and Alzheimer's Disease.
DB12087Vanillyl alcoholVanillyl alcohol has been used in trials studying the treatment of Smoking.
DB12179SecoisolariciresinolSecoisolariciresinol has been used in trials studying the prevention of Breast Cancer.
DB12226TerameprocolTerameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
DB12585OndelopranOndelopran has been used in trials studying the treatment of Alcohol Dependence.
DB12596CombretastatinCombretastatin has been investigated for the treatment of Anaplastic Thyroid Cancer.
DB12802PicropodophyllinPicropodophyllin has been investigated for the treatment of Non Small Cell Lung Cancer.
DB13205TeclozanTeclozan is an antiprotozoal agent employed typically as a therapy to treat protozoan infections.
DB13269Dichlorobenzyl alcoholA medication used to treat a sore throat.
DB13616MelagatranNot Annotated
DB14129MacelignanMacelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
DB09298SilibininCurrently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
DB148552-(aminomethyl)phenol2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study in Older Adults).
DB14921MavacamtenMavacamten is under investigation in clinical trial NCT03442764 (A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)).
DrugDrug NameTargetType
DB00179MasoprocolArachidonate 5-lipoxygenasetarget
DB00179MasoprocolArachidonate 5-lipoxygenaseenzyme
DB00179MasoprocolSex hormone-binding globulintarget
DB00773EtoposideDNA topoisomerase 2-alphatarget
DB00773EtoposideCytochrome P450 3A4enzyme
DB00773EtoposideCanalicular multispecific organic anion transporter 2transporter
DB00773EtoposideMultidrug resistance-associated protein 6transporter
DB00773EtoposideP-glycoprotein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 1transporter
DB00773EtoposideMultidrug resistance-associated protein 7transporter
DB00773EtoposideCanalicular multispecific organic anion transporter 1transporter
DB00773EtoposideATP-binding cassette sub-family G member 2transporter
DB00773EtoposideCytochrome P450 1A2enzyme
DB00773EtoposideCytochrome P450 2E1enzyme
DB00773EtoposideCytochrome P450 3A5enzyme
DB00773EtoposideUDP-glucuronosyltransferase 1-1enzyme
DB00773EtoposideDNA topoisomerase 2-betatarget
DB00773EtoposideGlutathione S-transferase theta-1enzyme
DB00773EtoposideGlutathione S-transferase Penzyme
DB00773EtoposideProstaglandin G/H synthase 2enzyme
DB00773EtoposideProstaglandin G/H synthase 1enzyme
DB01091ButenafineSqualene monooxygenasetarget
DB01179PodofiloxDNA topoisomerase 2-alphatarget
DB01179PodofiloxTubulin alpha-4A chaintarget
DB01179PodofiloxTubulin beta chaintarget
DB01626PargylineAmine oxidase [flavin-containing] Btarget
DB01626PargylineAmine oxidase [flavin-containing] Atarget
DB017112,3,4,5,6-Pentafluorobenzyl AlcoholAlcohol dehydrogenase 1Ctarget
DB02464BenzylamineTrypsin-1target
DB02464BenzylamineTrypsin-2target
DB02822Para-Bromobenzyl AlcoholAlcohol dehydrogenase 1Ctarget
DB030582-Aminobenzyl alcoholComplement factor Dtarget
DB04200MatairesinolDehydrogenase/reductase SDR family member 4-like 2target
DB04884Dapoxetine5-hydroxytryptamine receptor 1Atarget
DB04884Dapoxetine5-hydroxytryptamine receptor 1Btarget
DB04884Dapoxetine5-hydroxytryptamine receptor 2Ctarget
DB04884DapoxetineCytochrome P450 3A4enzyme
DB04884DapoxetineCytochrome P450 2D6enzyme
DB04898XimelagatranProthrombintarget
DB04898XimelagatranCytochrome P450 2C9enzyme
DB06654SafinamideAmine oxidase [flavin-containing] Btarget
DB06654SafinamideAmine oxidase [flavin-containing] Aenzyme
DB06654SafinamideATP-binding cassette sub-family G member 2transporter
DB06654SafinamideSolute carrier organic anion transporter family member 3A1transporter
DB06654SafinamideCytochrome P450 3A4enzyme
DB06654SafinamideCytochrome P450 1A1enzyme
DB06654SafinamideCytochrome P450 1A2enzyme
DB06654SafinamideCytochrome P450 2B6enzyme
DB06654SafinamideCytochrome P450 2C9enzyme
DB06654SafinamideCytochrome P450 2D6enzyme
DB06654SafinamideCytochrome P450 2C19enzyme
DB06654SafinamideCytochrome P450 2E1enzyme
DB06654SafinamideCytochrome P450 3A5enzyme
DB06770Benzyl alcoholCytochrome P450 2C8enzyme
DB06770Benzyl alcoholCytochrome P450 1A1enzyme
DB06770Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
DB06770Benzyl alcoholCytochrome P450 1A2enzyme
DB06770Benzyl alcoholCytochrome P450 2E1enzyme
DB06770Benzyl alcoholCytochrome P450 2D6enzyme
DB09082VilanterolCytochrome P450 3A4enzyme
DB09082VilanterolBeta-2 adrenergic receptortarget
DB13269Dichlorobenzyl alcoholSodium channel proteintarget
DB09298SilibininSolute carrier family 22 member 6transporter
DB09298SilibininUDP-glucuronosyltransferase 1-1enzyme
DB09298SilibininSolute carrier organic anion transporter family member 1B1transporter
DB09298SilibininSolute carrier organic anion transporter family member 1B3transporter
DB09298SilibininSolute carrier organic anion transporter family member 2B1transporter