Antineoplastic Agents, Phytogenic
- Antineoplastic Agents, Phytogenic
- Accession Number
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
Drug Drug Description Vindesine A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL). Vinorelbine A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC. Vincristine A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. Vinblastine A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. Etoposide A podophyllotoxin derivative used to treat testicular and small cell lung tumors. Podofilox A topical agent used for the treatment of external genital warts and perianal warts. Paclitaxel A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. Resveratrol Being investigated for the treatment of Herpes labialis infections (cold sores). Camptothecin Investigated for the treatment of cancer. Omacetaxine mepesuccinate A cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors. Podophyllin A cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata). Namitecan Namitecan has been used in trials studying the treatment of Solid Tumors. 10-hydroxycamptothecin 10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)). Fosbretabulin Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer. Combretastatin Combretastatin has been investigated for the treatment of Anaplastic Thyroid Cancer. Acteoside Acteoside is under investigation in clinical trial NCT02662283 (Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy). Sizofiran A beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach. Sizofiran has been used... Demecolcine Not Annotated Tetrandrine Not Annotated Cinnamaldehyde Cinnamaldehyde is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in... Combretastatin A4 Not Annotated Betulinic Acid Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. Silibinin Currently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning. Lorvotuzumab mertansine Lorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others. Ursolic acid Not Annotated
- Drugs & Drug Targets