Ethylenediamines

Name
Ethylenediamines
Accession Number
DBCAT000760
Description

Derivatives of ethylenediamine (the structural formula NH2CH2CH2NH2).

Drugs
DrugDrug Description
EthambutolAn antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB).
TripelennamineA histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold.
Edetic acidA chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
MethapyrileneMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
DP-b99Investigated for use/treatment in strokes and traumatic brain injuries.
MangafodipirAn organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas.
TriethylenetetramineA copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate.
Sodium feredetateNot Annotated
Drugs & Drug Targets
DrugTargetType
EthambutolProbable arabinosyltransferase Btarget
EthambutolProbable arabinosyltransferase Atarget
EthambutolProbable arabinosyltransferase Ctarget
TripelennamineHistamine H1 receptortarget
TripelennamineCytochrome P450 2D6enzyme
Edetic acidLeadtarget
Edetic acidIrontarget
Edetic acidManganese cationtarget
Edetic acidAdenosine deaminaseenzyme
Edetic acidSerum paraoxonase/lactonase 3enzyme
Edetic acidCytochrome P450 19A1enzyme
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
MangafodipirAlpha-2-macroglobulincarrier
MangafodipirSerum albumincarrier
MangafodipirSuperoxide dismutase [Mn], mitochondrialenzyme
MangafodipirNatural resistance-associated macrophage protein 2transporter
TriethylenetetramineGlypican-1transporter