Benzamides

BENZOIC ACID amides.
DrugDrug NameDrug Indication
DB00391SulpirideSulpiride is indicated for the treatment of schizophrenia.
DB00409RemoxiprideRemoxipride is an atypical antipsychotic once used for the treatment of schizophrenia.
DB06288AmisulprideInvestigated for use/treatment in schizophrenia and schizoaffective disorders, mania in bipolar disorder, and depression.
DB13025TiaprideTiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly.
DB00345Aminohippuric acidUsed to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.
DB00604CisaprideFor the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
DB00619ImatinibFor the treatment of Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML), Ph+ acute lymphoblastic leukaemia, myelodysplastic/myeloproliferative diseases, aggressive systemic mastocytosis, hypereosinophilic syndrome and/or chronic eosinophilic leukemia (CEL), dermatofibrosarcoma protuberans, and malignant gastrointestinal stromal tumors (GIST).
DB01035ProcainamideFor the treatment of life-threatening ventricular arrhythmias.
DB01168ProcarbazineFor use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease.
DB01171MoclobemideFor the treatment of depression.
DB01233MetoclopramideFor the treatment of gastroesophageal reflux disease (GERD). It is also used in treating nausea and vomiting, and to increase gastric emptying.
DB01393BezafibrateFor the treatment of primary hyperlipidaemia types IIa, IIb, III, IV and V (Fredrickson classification) corresponding to groups I, II and III of the European Atherosclerosis Society guidelines - when diet alone or improvements in lifestyle such as increased exercise or weight reduction do not lead to an adequate response. Also for the treatment of secondary hyperlipidaemias, e.g. severe hypertriglyceridemias, when sufficient improvement does not occur after correction of the underlying disorder (e.g. diabetes mellitus).
DB06799MethenamineFor prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug is not used to treat infection and should only be used after appropriate eradication of infection with antimicrobial agents.
DB070693-Hydroxyhippuric acidNot Available
DB08950IndoraminNot Available
DB09018BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the GI tract.
DB12518RacloprideNot Available
DrugDrug NameTargetType
DB00391SulpirideD(2) dopamine receptortarget
DB00391SulpirideD(3) dopamine receptortarget
DB00391SulpirideCholinesteraseenzyme
DB00391SulpirideCarbonic anhydrase 2target
DB00391SulpirideCarbonic anhydrase 3target
DB00409RemoxiprideD(2) dopamine receptortarget
DB00409RemoxiprideD(4) dopamine receptortarget
DB00409Remoxipride5-hydroxytryptamine receptor 2Atarget
DB00409RemoxiprideSigma non-opioid intracellular receptor 1target
DB00409RemoxiprideD(3) dopamine receptortarget
DB00409RemoxiprideCytochrome P450 2D6enzyme
DB06288AmisulprideD(2) dopamine receptortarget
DB06288AmisulprideD(3) dopamine receptortarget
DB06288Amisulpride5-hydroxytryptamine receptor 7target
DB06288Amisulpride5-hydroxytryptamine receptor 2Atarget
DB13025TiaprideD(2) dopamine receptortarget
DB13025TiaprideD(3) dopamine receptortarget
DB13025TiaprideSerotonin Receptorstarget
DB13025TiaprideAlpha-1 adrenergic receptorstarget
DB13025TiaprideAlpha-2 adrenergic receptorstarget
DB13025TiaprideHistamine H1 receptortarget
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidMultidrug resistance protein 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 1A2enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibBCR/ABL fusion protein isoform X9target
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibMultidrug resistance protein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB01035ProcainamideSodium channel protein type 5 subunit alphatarget
DB01035ProcainamideDNA (cytosine-5)-methyltransferase 1target
DB01035ProcainamideCytochrome P450 2D6enzyme
DB01035ProcainamideCholinesteraseenzyme
DB01035ProcainamideSolute carrier family 22 member 2transporter
DB01035ProcainamideSolute carrier family 22 member 1transporter
DB01035ProcainamideSolute carrier family 22 member 3transporter
DB01035ProcainamideSolute carrier family 22 member 5transporter
DB01035ProcainamideSolute carrier family 22 member 4transporter
DB01035ProcainamidePotassium voltage-gated channel subfamily H member 2target
DB01168ProcarbazineDNAtarget
DB01168ProcarbazineXanthine dehydrogenase/oxidaseenzyme
DB01168ProcarbazineCytochrome P450 1B1enzyme
DB01168ProcarbazineMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Atarget
DB01171MoclobemideCytochrome P450 2C19enzyme
DB01171MoclobemideCytochrome P450 2D6enzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Aenzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Benzyme
DB01171MoclobemideCytochrome P450 1A2enzyme
DB01171MoclobemideCytochrome P450 2C9enzyme
DB01233MetoclopramideMuscarinic acetylcholine receptor M1target
DB01233MetoclopramideD(2) dopamine receptortarget
DB01233MetoclopramideCytochrome P450 2D6enzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 4target
DB01233MetoclopramideCytochrome P450 11B1, mitochondrialenzyme
DB01233MetoclopramideCytochrome P450 11B2, mitochondrialenzyme
DB01233MetoclopramideSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 3Atarget
DB01233MetoclopramideAcetylcholinesterasetarget
DB01393BezafibratePeroxisome proliferator-activated receptor alphatarget
DB01393BezafibrateSolute carrier organic anion transporter family member 1B1transporter
DB01393BezafibratePeroxisome proliferator-activated receptor deltatarget
DB01393BezafibratePeroxisome proliferator-activated receptor gammatarget
DB01393BezafibrateCytochrome P450 1A1enzyme
DB01393BezafibrateCytochrome P450 2C8enzyme
DB01393BezafibrateCytochrome P450 3A4enzyme
DB01393BezafibrateNuclear receptor subfamily 1 group I member 2target
DB01393BezafibrateRetinoic acid receptor RXR-alphatarget
DB01393BezafibrateRetinoic acid receptor RXR-betatarget
DB01393BezafibrateRetinoic acid receptor RXR-gammatarget
DB070693-Hydroxyhippuric acidKynureninasetarget
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB09018BromoprideD(2) dopamine receptortarget
DB12518RacloprideD(2) dopamine receptortarget