NAV

Veralipride

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Veralipride
DrugBank Accession Number
DB13523
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 383.46
Monoisotopic: 383.151492091
Chemical Formula
C17H25N3O5S
Synonyms
  • Veraliprida
  • Veralipride
  • Veralipridum
External IDs
  • LIR 1660
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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1,2-BenzodiazepineThe risk or severity of CNS depression can be increased when 1,2-Benzodiazepine is combined with Veralipride.
AcetazolamideThe risk or severity of CNS depression can be increased when Acetazolamide is combined with Veralipride.
AcetophenazineThe risk or severity of CNS depression can be increased when Acetophenazine is combined with Veralipride.
AgomelatineThe risk or severity of CNS depression can be increased when Agomelatine is combined with Veralipride.
AlfentanilThe risk or severity of CNS depression can be increased when Alfentanil is combined with Veralipride.
Food Interactions
Not Available

Products

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International/Other Brands
Agradil / Agreal

Categories

ATC Codes
N05AL06 — Veralipride
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzenesulfonamides
Direct Parent
Benzenesulfonamides
Alternative Parents
Dimethoxybenzenes / Benzenesulfonyl compounds / Benzamides / Phenoxy compounds / Benzoyl derivatives / Anisoles / Alkyl aryl ethers / Organosulfonamides / N-alkylpyrrolidines / Aminosulfonyl compounds
show 7 more
Substituents
Alkyl aryl ether / Amine / Amino acid or derivatives / Aminosulfonyl compound / Anisole / Aromatic heteromonocyclic compound / Azacycle / Benzamide / Benzenesulfonamide / Benzenesulfonyl group
show 28 more
Molecular Framework
Aromatic heteromonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
S7064109UD
CAS number
66644-81-3
InChI Key
RYJXBGGBZJGVQF-UHFFFAOYSA-N
InChI
InChI=1S/C17H25N3O5S/c1-4-7-20-8-5-6-12(20)11-19-17(21)14-9-13(26(18,22)23)10-15(24-2)16(14)25-3/h4,9-10,12H,1,5-8,11H2,2-3H3,(H,19,21)(H2,18,22,23)
IUPAC Name
2,3-dimethoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-5-sulfamoylbenzamide
SMILES
COC1=CC(=CC(C(=O)NCC2CCCN2CC=C)=C1OC)S(N)(=O)=O

References

General References
Not Available
ChemSpider
43638
RxNav
39468
ChEBI
135600
ChEMBL
CHEMBL2105581
Wikipedia
Veralipride

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Capsule, coatedOral100 mg
Capsule
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.285 mg/mLALOGPS
logP1.52ALOGPS
logP0.55Chemaxon
logS-3.1ALOGPS
pKa (Strongest Acidic)10.06Chemaxon
pKa (Strongest Basic)7.77Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area110.96 Å2Chemaxon
Rotatable Bond Count8Chemaxon
Refractivity99.51 m3·mol-1Chemaxon
Polarizability39.87 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-001i-1009000000-46d66e3d2a073ee6d387
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-001l-0009000000-91745c1ece090ae0729c
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-001i-2209000000-b10ff7ffff38ac40f3a4
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-01t9-4109000000-65e59c84ed443536c96b
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-000w-9242000000-8b74e20fc0a27b51620c
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-004i-9024000000-acd1e62d17eb03268b28
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-183.77238
predicted
DeepCCS 1.0 (2019)
[M+H]+186.13039
predicted
DeepCCS 1.0 (2019)
[M+Na]+192.22354
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:43 / Updated at February 21, 2021 18:54