Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.
DrugDrug NameDrug Indication
DB11780AllicinNot Available
DB11785AnisodamineNot Available
DB12243EdaravoneIndicated for improving neurological symptoms and damage from acute ischemic stroke and delaying disease progression of ALS.
DB00435Nitric OxideFor the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
DB00437AllopurinolFor the treatment of hyperuricemia associated with primary or secondary gout. Also indicated for the treatment of primary or secondary uric acid nephropathy, with or without the symptoms of gout, as well as chemotherapy-induced hyperuricemia and recurrent renal calculi.
DB00806PentoxifyllineFor the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs.
DB01093Dimethyl sulfoxideFor the symptomatic relief of patients with interstitial cystitis.
DB036443-Hydroxyanthranilic AcidNot Available
DB04066para-Coumaric AcidNot Available
DB06151AcetylcysteineAcetylcysteine is used mainly as a mucolytic and in the management of paracetamol (acetaminophen) overdose.
DB07767Ferulic acidNot Available
DrugDrug NameTargetType
DB00435Nitric OxideGuanylate cyclase soluble subunit alpha-2target
DB00435Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
DB00435Nitric OxideCytochrome P450 1A2enzyme
DB00435Nitric OxideCytochrome P450 2B6enzyme
DB00435Nitric OxideCytochrome P450 3A4enzyme
DB00435Nitric OxideMetallothionein-1Atarget
DB00435Nitric OxideIndoleamine 2,3-dioxygenase 1target
DB00437AllopurinolXanthine dehydrogenase/oxidasetarget
DB00437AllopurinolSolute carrier family 22 member 8transporter
DB00437AllopurinolSolute carrier family 22 member 7transporter
DB00437AllopurinolAldehyde oxidaseenzyme
DB00437AllopurinolXanthine dehydrogenase/oxidaseenzyme
DB00806PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00806PentoxifyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB00806Pentoxifylline5'-nucleotidasetarget
DB00806PentoxifyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB00806PentoxifyllineAdenosine receptor A1target
DB00806PentoxifyllineAdenosine receptor A2atarget
DB00806PentoxifyllineCytochrome P450 1A2enzyme
DB01093Dimethyl sulfoxideTransthyretincarrier
DB01093Dimethyl sulfoxideCytochrome P450 2C19enzyme
DB01093Dimethyl sulfoxideCytochrome P450 2D6enzyme
DB01093Dimethyl sulfoxideCytochrome P450 3A4enzyme
DB036443-Hydroxyanthranilic AcidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
DB04066para-Coumaric AcidPhotoactive yellow proteintarget
DB04066para-Coumaric AcidPPHtarget
DB04066para-Coumaric AcidProstaglandin reductase 1target
DB04066para-Coumaric AcidHistidine ammonia-lyasetarget
DB06151AcetylcysteineSolute carrier organic anion transporter family member 1B1transporter
DB06151AcetylcysteineNAPQI (N-acetyl-p-benzoquinone imine)target
DB06151AcetylcysteineSolute carrier family 22 member 6transporter
DB06151AcetylcysteineAminoacylase-1target
DB06151AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB06151AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB06151AcetylcysteineGlutathione synthetasetarget
DB06151AcetylcysteineCystine/glutamate transportertarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Btarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 1target
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Atarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 2Dtarget
DB06151AcetylcysteineGlutamate receptor ionotropic, NMDA 3Atarget
DB07767Ferulic acidEndo-1,4-beta-xylanase Ytarget
DB07767Ferulic acidEndo-1,4-beta-xylanase Ztarget
DB07767Ferulic acidEst1etarget
DB07767Ferulic acidO-methyltransferasetarget