Folic Acid and Derivatives
- Folic Acid and Derivatives
- Accession Number
- DBCAT001033 (DBCAT001031, DBCAT001032, DBCAT002079, DBCAT002146, DBCAT002158, DBCAT003386)
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
- ATC Classification
Drug Drug Description Tetrahydrofolic acid For nutritional supplementation, also for treating dietary shortage or imbalance. Leucovorin A folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer. Levoleucovorin A folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. Folic acid A nutrient used to treat megaloblastic anemia and is found in many supplements. Levomefolic acid A folate supplement used to prevent neural tube defects in pregnancy or folate deficiency. Triglu-5-formyl-tetrahydrofolate Not Available (6S)-5,6,7,8-tetrahydrofolic acid Not Available 5-methyltetrahydrofolic acid 5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine... (6R)-Folinic acid Not Available
- Drugs & Drug Targets