Benzylisoquinolines

ISOQUINOLINES with a benzyl substituent.
DrugDrug NameDrug Indication
DB00416Metocurine IodideFor use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
DB00565CisatracuriumFor inpatients and outpatients as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation in the ICU.
DB00714ApomorphineFor the acute, intermittent treatment of hypomobility, off episodes (end-of-dose wearing off and unpredictable on/off episodes) associated with advanced Parkinson's disease.
DB00732Atracurium besylateFor use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
DB01113PapaverineFor the treatment of impotence and vasospasms.
DB01199TubocurarineUsed as a diagnosis agent for myasthenia gravis, and also to facilitate the intubation after induction of anesthesia in surgical procedure
DB01336MetocurineMetocurine is a muscle relaxant.
DB04115BerberineNot Available
DB06751DrotaverineUsed in the treatment of functional bowel disorders and alleviating pain in renal colic.
DB11562BicucullineNot Available
DB12093TetrahydropalmatineNot Available
DB12251MoxaverineNot Available
DB13295AtracuriumNot Available
DB13648AlcuroniumNot Available
DB13692TretoquinolNot Available
DrugDrug NameTargetType
DB00416Metocurine IodideNeuronal acetylcholine receptor subunit alpha-2target
DB00565CisatracuriumNeuronal acetylcholine receptor subunit alpha-2target
DB00714ApomorphineDopamine D2 receptortarget
DB00714ApomorphineDopamine D1 receptortarget
DB00714ApomorphineDopamine D4 receptortarget
DB00714ApomorphineDopamine D3 receptortarget
DB00714ApomorphineDopamine D5 receptortarget
DB00714ApomorphineNeuron-specific vesicular protein calcyontarget
DB00714ApomorphineAlpha-2C adrenergic receptortarget
DB00714ApomorphineAlpha-2B adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Ctarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Btarget
DB00714ApomorphineAlpha-2A adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Dtarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Btarget
DB00732Atracurium besylateNeuronal acetylcholine receptor subunit alpha-2target
DB01113PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01113PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
DB01199TubocurarineAcetylcholinesterasetarget
DB01199Tubocurarine5-hydroxytryptamine receptor 3Atarget
DB01199TubocurarineSolute carrier family 22 member 1transporter
DB01199TubocurarineSolute carrier family 22 member 2transporter
DB01199TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
DB01199TubocurarineCholinesteraseenzyme
DB01336MetocurineNeuronal acetylcholine receptor subunit alpha-2target
DB01336MetocurineMuscarinic acetylcholine receptor M2target
DB04115BerberineHTH-type transcriptional regulator QacRtarget
DB04115BerberineBaculoviral IAP repeat-containing protein 5target
DB06751DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB06751DrotaverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB12093TetrahydropalmatineDopamine D1 receptortarget
DB12093TetrahydropalmatineDopamine D2 receptortarget
DB12093TetrahydropalmatineCytochrome P450 3A4enzyme