Detoxifying Agents for Antineoplastic Treatment
- Detoxifying Agents for Antineoplastic Treatment
- Accession Number
- Not Available
- ATC Classification
Drug Drug Description Palifermin A form of recombinant human keratinocyte growth factor used to prevent and treat oral mucositis following radiation or chemotherapy. Dexrazoxane A cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer. Leucovorin A folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer. Amifostine A cytoprotective adjuvant used for reduction in the cumulative renal toxicity in patients with ovarian cancer and moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer. Glucarpidase A carboxypeptidase enzyme used to treat toxic plasma methotrexate concentrations by providing an alternate elimination pathway for methotrexate in patients who have impaired renal function. Coenzyme M A uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract. Levoleucovorin A folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. Rasburicase A recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.
- Drugs & Drug Targets