Tumour Detection

DrugDrug NameDrug Indication
DB00057Indium In-111 satumomab pendetideFor diagnosis of extrahepatic malignant cancers
DB00089Capromab pendetideFor diagnosis of prostate cancer and detection of intra-pelvic metastases.
DB00113Technetium Tc-99m arcitumomabFor imaging colorectal tumors
DB09266Technetium Tc-99m tilmanoceptIndicated with or without scintigraphic imaging for lymphatic mapping using a handheld gamma counter to locate lymph nodes draining a primary tumor site in patients with solid tumors for which this procedure is a component of intraoperative management [FDA Label]. Indicated with or without scintigraphic imaging for guiding sentinel lymph node biopsy using a handheld gamma counter in patients with clinically node negative squamous cell carcinoma of the oral cavity, breast cancer or melanoma [FDA Label].
DB09398Fluoride ion F-1818F is used as a bone imaging agent to define areas of altered osteogenic activity. It has been indicated for back pain and otherwise unexplained bone pain, child abuse, abnormal radiographic or laboratory findings, osteomyelitis, trauma, inflammatory and degenerative arthritis, avascular necrosis. Osteonecrosis of the mandible, condylar hyperplasia, and metabolic bone disease are also among the indications for fluoride imaging.
DB09502Fludeoxyglucose (18F)The uptake of 18F-FDG by tissues is a marker for the tissue uptake of glucose, which in turn is closely correlated with certain types of tissue metabolism. Fludeoxyglucose F 18 Injection is indicated in positron emission tomography (PET) imaging for assessment of abnormal glucose metabolism to assist in the evaluation of malignancy in patients with known or suspected abnormalities found by other testing modalities, or in patients with an existing diagnoses of cancer.
DB13848Fluorodopa (18F)Not Available
DB06704IobenguaneDetection of primary and metastatic pheochromocytoma or neuroblastoma
DB11835Indium In-111 pentetreotideNot Available
DB13146Fluciclovine (18F)Fluciclovine is indicated as a detection agent for positron emission tomography (PET) in men with suspected prostate cancer recurrence based on elevated blood prostate specific antigen (PSA) levels following prior treatment.[A31388] The overexpression of L-type amino acid transporters such as LAT1 and LAT3 that mediate the uptake of essential amino acids has been extensively reported as a tumoral mechanism of cell growth.[A31389]
DrugDrug NameTargetType
DB00057Indium In-111 satumomab pendetideTumor-associated glycoprotein 72 (TAG-72)target
DB00089Capromab pendetideGlutamate carboxypeptidase 2target
DB00113Technetium Tc-99m arcitumomabCarcinoembryonic antigen-related cell adhesion molecule 1target
DB09266Technetium Tc-99m tilmanoceptMacrophage mannose receptor 1target
DB09502Fludeoxyglucose (18F)Hexokinase-1enzyme
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 4transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 2transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 1transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 3transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 9transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 5transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 6transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 7transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 8transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 10transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 11transporter
DB09502Fludeoxyglucose (18F)Solute carrier family 2, facilitated glucose transporter member 12transporter
DB06704IobenguaneSodium-dependent noradrenaline transportertransporter
DB13146Fluciclovine (18F)Neutral amino acid transporter B(0)target
DB13146Fluciclovine (18F)Y+L amino acid transporter 1target
DB13146Fluciclovine (18F)Cationic amino acid transporter 3target
DB13146Fluciclovine (18F)Glutamate (NMDA) receptortarget
DB13146Fluciclovine (18F)Glutamate receptor 1target
DB13146Fluciclovine (18F)Glutamate receptor 2target
DB13146Fluciclovine (18F)Glutamate receptor 3target
DB13146Fluciclovine (18F)Glutamate receptor 4target
DB13146Fluciclovine (18F)Multidrug resistance protein 1transporter
DB13146Fluciclovine (18F)Multidrug resistance-associated protein 4transporter