Urinary Alkalinisers

Drugs that increase urinary pH.
DrugDrug NameDrug Indication
DB01390Sodium bicarbonateSodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate. Further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturateprotein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments.
DB04272Citric acidNot Available
DB09459L-tartaric acidTartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic.
DB09154Sodium citrateUsed as an anticoagulant during plasmophoresis as well as a neutralizing agent in the treatment of upset stomach and acidic urine [FDA Label] [L788] [L789].
DB09125Potassium CitrateFor the management of renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
DrugDrug NameTargetType
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 1transporter
DB01390Sodium bicarbonateSodium bicarbonate cotransporter 3transporter
DB01390Sodium bicarbonateElectroneutral sodium bicarbonate exchanger 1transporter
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 4transporter
DB01390Sodium bicarbonateHydrogen ionstarget
DB01390Sodium bicarbonateSodium-driven chloride bicarbonate exchangertransporter
DB04272Citric acidCell division protein FtsZtarget
DB04272Citric acidAngiogenintarget
DB04272Citric acidBeta-lactamase 2target
DB04272Citric acidUridine-cytidine kinase 2target
DB04272Citric acidTumor necrosis factor ligand superfamily member 13Btarget
DB04272Citric acidBetaine--homocysteine S-methyltransferase 1target
DB04272Citric acidTryptophan--tRNA ligasetarget
DB04272Citric acidAldose reductasetarget
DB04272Citric acidCitrate synthase, mitochondrialtarget
DB04272Citric acidHeparan sulfate glucosamine 3-O-sulfotransferase 3A1target
DB04272Citric acidcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB04272Citric acidProto-oncogene tyrosine-protein kinase Srctarget
DB04272Citric acidRibonuclease pancreatictarget
DB04272Citric acidIsocitrate dehydrogenase [NADP]target
DB04272Citric acidGlycine N-methyltransferasetarget
DB04272Citric acidEosinophil cationic proteintarget
DB04272Citric acidBeta-lactamasetarget
DB04272Citric acidMolybdenum cofactor guanylyltransferasetarget
DB04272Citric acidFumarate hydratase class IItarget
DB04272Citric acid6-phosphogluconolactonasetarget
DB04272Citric acidOxygen-insensitive NAD(P)H nitroreductasetarget
DB04272Citric acidGag-Pro-Pol polyproteintarget
DB04272Citric acidL-amino-acid oxidasetarget
DB04272Citric acidMacrophage migration inhibitory factortarget
DB04272Citric acidCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1target
DB04272Citric acid1-deoxy-D-xylulose 5-phosphate reductoisomerasetarget
DB04272Citric acidTryptophan synthase alpha chaintarget
DB04272Citric acidSialidasetarget
DB04272Citric acidKHG/KDPG aldolasetarget
DB04272Citric acidCytochrome c peroxidasetarget
DB04272Citric acidHepatocyte growth factor-regulated tyrosine kinase substratetarget
DB04272Citric acidInvasintarget
DB04272Citric acidIntron-associated endonuclease 1target
DB04272Citric acidShort tail fiber proteintarget
DB04272Citric acidMalate dehydrogenase, mitochondrialtarget
DB04272Citric acidN5-carboxyaminoimidazole ribonucleotide mutasetarget
DB04272Citric acid50S ribosomal protein L4target
DB04272Citric acidCarboxypeptidase Btarget
DB04272Citric acidHexon proteintarget
DB04272Citric acidRiboflavin biosynthesis protein RibFtarget
DB04272Citric acidBeta-fructosidasetarget
DB04272Citric acidPutative stringent starvation protein Atarget
DB04272Citric acidCitrate synthasetarget
DB04272Citric acidRNA 3'-terminal phosphate cyclasetarget
DB04272Citric acidU6 snRNA-associated Sm-like protein LSm6target
DB04272Citric acidPleckstrin homology domain-containing family A member 1target
DB04272Citric acidFe(3+)-binding periplasmic proteintarget
DB04272Citric acidSignal recognition particle receptor FtsYtarget
DB04272Citric acidNicotinate-nucleotide adenylyltransferasetarget
DB04272Citric acidN utilization substance protein B homologtarget
DB04272Citric acidComplement component C8 gamma chaintarget
DB04272Citric acidRibonucleoside-diphosphate reductase subunit betatarget
DB04272Citric acidGlutamine synthetase 1target
DB04272Citric acidCitrate synthasetarget
DB04272Citric acidProstaglandin F synthasetarget
DB04272Citric acidAdenine phosphoribosyltransferasetarget
DB04272Citric acidGlucose-1-phosphate thymidylyltransferasetarget
DB04272Citric acidGlyoxalase family proteintarget
DB04272Citric acidLaccase domain protein YfiHtarget
DB04272Citric acidRibose-5-phosphate isomerase Atarget
DB04272Citric acidGMP synthase [glutamine-hydrolyzing]target
DB04272Citric acidInosine triphosphate pyrophosphatasetarget
DB04272Citric acidLysozymetarget
DB04272Citric acidGlycerol uptake operon antiterminator regulatory proteintarget
DB04272Citric acid3-carboxy-cis,cis-muconate cycloisomerasetarget
DB04272Citric acidPyruvate decarboxylasetarget
DB04272Citric acidSolute carrier organic anion transporter family member 2B1transporter
DB09459L-tartaric acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1enzyme
DB09459L-tartaric acidHypoxia-inducible factor 1-alpha inhibitorenzyme
DB09154Sodium citrateMitochondrial 2-oxodicarboxylate carriertransporter
DB09154Sodium citrateSolute carrier family 13 member 2transporter
DB09154Sodium citrateSolute carrier family 13 member 5transporter
DB09154Sodium citrateTricarboxylate transport protein, mitochondrialtransporter