Pegylated agents

DrugDrug NameDrug Description
DB05202Egaptivon pegolPlatelet aggregation, thrombosis and acute coronary syndromes
DB12578Lexaptepid PegolLexaptepid Pegol has been used in trials studying the treatment of Anemia, Inflammation, Chronic Diseases, End Stage Renal Disease, and Anemia of Chronic Disease.
DB08894PeginesatidePeginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis
DB13200LipegfilgrastimA medication used to reduce the duration of chemotherapy-induced neutropenia and incidence of febrile neutropenia in cytotoxic chemotherapy.
DB12258Abicipar PegolAbicipar Pegol has been used in trials studying the treatment of Macular Edema and Macular Degeneration.
DB14712ElapegademaseA recombinant adenosine deaminase used to treat adenosine deaminase severe combined immune deficiency.
DB05321PEG-uricaseInvestigated for use/treatment in hyperuricemia.
DB09329Antihemophilic Factor (Recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
DB11661Eptacog alfa pegol (activated)Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With...
DB00061PegademaseA modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes.
DB12842PegamotecanPegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.
DB09122Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
DB06022GlycoPEG-GCSFInvestigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
DB04895PegaptanibA selective vascular endothelial growth factor (VEGF) antagonist used for the treatment of neovascular (wet) age-related macular degeneration.
DB09208PegloticaseA recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy.
DB08904Certolizumab pegolA tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis.
DB06293PegnivacoginInvestigated for use/treatment in thrombosis, coronary artery disease, and vascular diseases.
DB11707Olaptesed PegolOlaptesed Pegol has been investigated for the treatment of Hematopoietic Stem Cell Transplantation.
DB06325PegpleranibInvestigated for use/treatment in macular degeneration and eye disorders/infections.
DB03394Heptaethylene glycolNot Annotated
DB11225Peg-100 stearateNot Annotated
DB06611PegsunerceptInvestigated for use/treatment in rheumatoid arthritis.
DB14700Damoctocog alfa pegolA recombinant Factor VIII used to treat hemophilia A to control bleeding, perioperative bleeding, and also for prophylaxis of bleeding.
DB11567Insulin peglisproNot Annotated
DB12839PegvaliaseAn enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment.
DB14142Methoxy PEG-12 retinamideNot Annotated
DB09107Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
DB12814Cepeginterferon alfa-2BCepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
DB13933Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
DB00059PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
DB06811PolidocanolA sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
DB00008Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
DB05860Peginterferon alfacon-1Investigated for use/treatment in hepatitis (viral, C).
DB00022Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
DB01839Propylene glycolA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
DB09287Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
DB11077Polyethylene glycol 400An ingredient used in a wide variety of medications, and is not an approved medication.
DB00082PegvisomantA growth hormone receptor antagonist used to treat acromegaly.
DB00019PegfilgrastimA recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
DrugDrug NameTargetType
DB05202Egaptivon pegolvon Willebrand factortarget
DB05202Egaptivon pegolPlatelet glycoprotein Ib alpha chaintarget
DB08894PeginesatideErythropoietin receptortarget
DB13200LipegfilgrastimGranulocyte colony-stimulating factor receptortarget
DB05321PEG-uricaseUric acid degradation bifunctional proteintarget
DB09329Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factortarget
DB09329Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factorcarrier
DB00061PegademaseGrowth factor receptor-bound protein 2target
DB09122Peginterferon beta-1aCytochrome P450 1A2enzyme
DB09208PegloticaseUric acidtarget
DB08904Certolizumab pegolTumor necrosis factortarget
DB08904Certolizumab pegolAlcohol dehydrogenase [NADP(+)]enzyme
DB06325PegpleranibPlatelet-derived growth factor subunit Btarget
DB03394Heptaethylene glycolCarbonyl reductase [NADPH] 1target
DB14700Damoctocog alfa pegolCoagulation factor VIIItarget
DB11567Insulin peglisproCytochrome P450 1A2enzyme
DB09107Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
DB12814Cepeginterferon alfa-2BCytochrome P450 1A2enzyme
DB13933Nonacog beta pegolCoagulation factor VIItarget
DB13933Nonacog beta pegolCoagulation factor VIIItarget
DB13933Nonacog beta pegolCoagulation factor Xtarget
DB00059PegaspargaseThyroxine-binding globulincarrier
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 2target
DB00008Peginterferon alfa-2aInterferon alpha/beta receptor 1target
DB00008Peginterferon alfa-2aCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 1target
DB00022Peginterferon alfa-2bInterferon alpha/beta receptor 2target
DB00022Peginterferon alfa-2bCytochrome P450 1A2enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2D6enzyme
DB00022Peginterferon alfa-2bCytochrome P450 2C9enzyme
DB01839Propylene glycolCoagulation factor XIII A chaintarget
DB01839Propylene glycolHaloalkane dehalogenasetarget
DB01839Propylene glycolClavaminate synthase 1target
DB01839Propylene glycolLactaldehyde reductasetarget
DB01839Propylene glycolB12-independent glycerol dehydratasetarget
DB11077Polyethylene glycol 400Oxidoreductase HTATIP2target
DB11077Polyethylene glycol 400Cytochrome P450 4A11enzyme
DB11077Polyethylene glycol 400Alcohol dehydrogenase class-3enzyme
DB11077Polyethylene glycol 400Sulfotransferase 1A1enzyme
DB11077Polyethylene glycol 400Ectonucleotide pyrophosphatase/phosphodiesterase family member 1target
DB11077Polyethylene glycol 400P-glycoprotein 1transporter
DB00082PegvisomantGrowth hormone receptortarget
DB00082PegvisomantSterol 26-hydroxylase, mitochondrialenzyme
DB00082PegvisomantGlutamine synthetaseenzyme
DB00082PegvisomantCytochrome P450 2C18enzyme
DB00082PegvisomantCytochrome P450 3A4enzyme
DB00082PegvisomantCytochrome P450 4A11enzyme
DB00019PegfilgrastimGranulocyte colony-stimulating factor receptortarget
DB00019PegfilgrastimNeutrophil elastaseenzyme