Phleum pratense pollen

Identification

Name
Phleum pratense pollen
Accession Number
DB10394  (DB05357, DB05908)
Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Allergenics
Allergen Extract
Description

Phleum pratense pollen allergenic extract is used in allergenic testing.

Synonyms
  • Allergenic extract, grass, timothy
  • Allergenic extract, timothy grass
  • Allergenic extract,timothy grass pollen
  • Common timothy pollen
  • Grass pollen extract
  • Phleum nodosum pollen
  • Phleum pratense
  • Phleum pratense pollen extract
  • Standardized timothy grass pollen
  • Timothy grass (phleum pretense) pollen standardized
  • Timothy grass pollen
  • Timothy grass pollen extract
  • Timothy grass pollen extracts
  • Timothy pollen
Active Moieties
NameKindUNIICASInChI Key
Phleum pratense topunknownS7PW24BX20Not AvailableNot applicable
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Allergen Pack Timothy GrassSolution10000 [BAU]/1mLIntradermal; SubcutaneousAlvix Laboratories2015-07-092018-03-08Us
Allergenic Extract - Standardized Grass Pollen - TimothyLiquidIntradermal; SubcutaneousGreer Laboratories2015-03-10Not applicableCanada
Allergenic Extract - Standardized Grass Pollen - TimothyLiquidIntradermal; SubcutaneousGreer Laboratories2000-10-30Not applicableCanada
Allergenic Extract - Standardized Timothy Grass PollenLiquidIntradermal; Percutaneous; SubcutaneousAlk Abello, Inc.2009-07-30Not applicableCanada
Center-AL - Phleum Pratense PollenInjection, suspension20000 [PNU]/1mLSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
Center-AL - Phleum Pratense PollenInjection, suspension10000 [PNU]/1mLSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
GrastekTablet2800 [BAU]/1SublingualMerck Sharp & Dohme Corp.2014-04-112017-08-18Us
GrastekTablet2800 [BAU]/1SublingualALK-Abelló A/S2014-04-11Not applicableUs
GrastekTablet, orally disintegrating2800 unitSublingualAlk Abello A/S2014-01-14Not applicableCanada
OralairTablet100 [IR]SublingualStallergenes Canada Inc2012-07-26Not applicableCanada
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
5 Grass MixPhleum pratense pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Anthoxanthum odoratum (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Poa pratensis pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
5 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
5 Grass MixPhleum pratense pollen (100 [PNU]/1mL) + Agrostis gigantea pollen (100 [PNU]/1mL) + Anthoxanthum odoratum pollen (100 [PNU]/1mL) + Dactylis glomerata pollen (100 [PNU]/1mL) + Poa pratensis pollen (100 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
5 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
5 Grass MixPhleum pratense pollen (5000 [PNU]/1mL) + Agrostis gigantea pollen (5000 [PNU]/1mL) + Anthoxanthum odoratum pollen (5000 [PNU]/1mL) + Dactylis glomerata pollen (5000 [PNU]/1mL) + Poa pratensis pollen (5000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
5 Grass MixPhleum pratense pollen (1000 [PNU]/1mL) + Agrostis gigantea pollen (1000 [PNU]/1mL) + Anthoxanthum odoratum pollen (1000 [PNU]/1mL) + Dactylis glomerata pollen (1000 [PNU]/1mL) + Poa pratensis pollen (1000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
6 Grass MixPhleum pratense pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Festuca pratensis pollen (20000 [PNU]/1mL) + Lolium perenne pollen (20000 [PNU]/1mL) + Poa pratensis pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
6 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Festuca pratensis pollen (10000 [PNU]/1mL) + Lolium perenne pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
7 Grass MixPhleum pratense pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Anthoxanthum odoratum (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Festuca pratensis pollen (20000 [PNU]/1mL) + Lolium perenne pollen (20000 [PNU]/1mL) + Poa pratensis pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
7 Grass MixPhleum pratense pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Festuca pratensis pollen (10000 [PNU]/1mL) + Lolium perenne pollen (10000 [PNU]/1mL) + Poa pratensis pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUs
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Allergen Pack Timothy GrassPhleum pratense pollen (10000 [BAU]/1mL)SolutionIntradermal; SubcutaneousAlvix Laboratories2015-07-092018-03-08Us
Categories
UNII
65M88RW2EG
CAS number
Not Available

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcebutololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Acebutolol.
AlprenololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Alprenolol.
AnisodamineThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Anisodamine.
ArotinololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Arotinolol.
AtenololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Atenolol.
BefunololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Befunolol.
BenazeprilThe risk or severity of adverse effects can be increased when Benazepril is combined with Phleum pratense pollen.
BenazeprilatThe risk or severity of adverse effects can be increased when Benazeprilat is combined with Phleum pratense pollen.
BetaxololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Betaxolol.
BevantololThe risk of a hypersensitivity reaction to Phleum pratense pollen is increased when it is combined with Bevantolol.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
Not Available

References

General References
  1. TePas EC, Hoyte EG, McIntire JJ, Umetsu DT: Clinical efficacy of microencapsulated timothy grass pollen extract in grass-allergic individuals. Ann Allergy Asthma Immunol. 2004 Jan;92(1):25-31. [PubMed:14756461]
  2. Patel P, Salapatek AM: Pollinex Quattro: a novel and well-tolerated, ultra short-course allergy vaccine. Expert Rev Vaccines. 2006 Oct;5(5):617-29. [PubMed:17181436]
External Links
PubChem Substance
347910569
RxNav
851994
AHFS Codes
  • 92:05.00* — Allergenic Extracts

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3CompletedTreatmentSeasonal Allergic Rhinitis (SAR)1
4CompletedTreatmentRhinitis, Allergic, Seasonal1
4CompletedTreatmentRhinoconjunctivitis, Allergic1
Not AvailableCompletedNot AvailableAllergies1
Not AvailableSuspendedBasic ScienceImmunologic Desensitization1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
Injection, solutionSubcutaneous
SolutionIntradermal; Subcutaneous10000 [BAU]/1mL
LiquidIntradermal; Percutaneous; Subcutaneous
LiquidIntradermal; Subcutaneous
LiquidIntradermal; Percutaneous; Subcutaneous
LiquidSubcutaneous
SolutionIntradermal; Subcutaneous
Injection, suspensionSubcutaneous10000 [PNU]/1mL
Injection, suspensionSubcutaneous20000 [PNU]/1mL
Injection, solutionPercutaneous
TabletSublingual2800 [BAU]/1
Tablet, orally disintegratingSublingual2800 unit
KitSublingual
TabletSublingual100 [IR]
TabletSublingual300 [IR]
Tablet, orally disintegratingSublingual
LiquidIntradermal
SolutionPercutaneous; Subcutaneous
Injection, solutionIntradermal
Injection, solutionPercutaneous; Subcutaneous
Injection, solutionIntradermal100 [BAU]/1mL
Injection, solutionIntradermal1000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous10000 [BAU]/1mL
InjectionCutaneous; Intradermal; Subcutaneous100000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous10000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous100000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous100000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous10000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous100000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous
Injection, solutionSubcutaneous10000 [BAU]/1mL
Injection, solutionSubcutaneous100000 [BAU]/1mL
SolutionPercutaneous10000 [BAU]/1mL
SolutionPercutaneous100000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on December 01, 2015 13:03 / Updated on July 10, 2020 18:30

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