Complex Mixtures

Name
Complex Mixtures
Accession Number
DBCAT000109
Description

Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.

Drugs
DrugDrug Description
ZiconotideAn N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.
FerumoxsilNot Annotated
Rice bran oilRice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It...
Linseed oilLinseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic...
SennosidesA laxative used to treat constipation.
Ginkgo bilobaA herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders.
Talimogene laherparepvecA genetically modified virus used to treat recurrent melanoma, or metastatic melanoma.
Maritime pine extractA plant extract in nutritional supplements for healthy hair, skin, and nails.
AncrodAn anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country.
SerotoninFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
CenderitideCenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall.
CilengitideCilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others.
AnfibatideAnfibatide is under investigation in clinical trial NCT01585259 (Anfibatide Phase Ib-IIa Clinical Trial).
MenotropinsA purified combination of human luteinizing hormone and follicle stimulating hormone used to treat female infertility.
Botulinum toxin type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
Insulin glargineA modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus.
InfliximabA monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.
PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
Antithymocyte immunoglobulin (rabbit)A purified form of rabbit anti-thymocyte antibodies used for immunosuppression in patients receiving kidney transplants.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Ethiodized oilA contrast agent used in imaging procedures.
St. John's WortAn herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety.
Ephedra sinica rootAn alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
GinsengA herbal supplement used in many health products.
BufotenineA hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a...
CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
G17DT ImmunogenIntended for the treatment of various forms of cancer.
BZL101Investigated for use/treatment in breast cancer.
INGN 201Investigated for use/treatment in bladder cancer, brain cancer, breast cancer, esophageal cancer, head and neck cancer, lung cancer, oral cavity cancer, ovarian cancer, and prostate cancer.
INGN 225Investigated for use/treatment in breast cancer, head and neck cancer, and lung cancer.
ObiltoxaximabA monoclonal antibody used for prophylaxis or treatment of inhalational anthrax.
RindopepimutInvestigated for use/treatment in brain cancer.
NeovastatInvestigated for use/treatment in kidney cancer, lung cancer, macular degeneration, multiple myeloma, prostate cancer, and psoriasis and psoriatic disorders.
SRP 299Investigated for use/treatment in asthma, atopic dermatitis, and pediatric atopic dermatitis indications.
TA-NICInvestigated for use/treatment in tobacco dependence.
Chlorotoxin I-131Investigated for use/treatment in various forms of brain cancer; Malignant Glioma, Glioblastoma Multiforme, GBM, Anaplastic Astrocytoma, Oligo-Astrocytoma, Gliosarcoma
alpha-Conotoxin VC 1.1Investigated for use/treatment in pain (acute or chronic).
LLL-3348Investigated for use/treatment in psoriasis and psoriatic disorders.
GI-5005Investigated for use/treatment in hepatitis (viral, C).
VitespenInvestigated for use/treatment in kidney cancer, melanoma, renal cell carcinoma, lymphoma (unspecified), colorectal cancer, and brain cancer.
CalfactantA lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants.
TG4010Investigated for use/treatment in breast cancer, renal cell carcinoma, prostate cancer, and lung cancer.
Sipuleucel-TAn autologous cellular immunotherapy indicated for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.
BeractantA pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants.
BatroxobinNo approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously.
PodophyllinA cytotoxic agent used for the removal of soft genital (venereal) warts (condylomata acuminata).
Poractant alfaA pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants.
Chorionic Gonadotropin (Human)A naturally-occurring hormone produced during human placenta used for the treatment of prepubertal cryptorchidism and hypogonadotropic hypogonadism in selected males, and induction of pregnancy in selected infertile women.
Antilymphocyte immunoglobulin (horse)A primarily IgG immune globulin used to manage allograft rejection in renal transplant patients.
Soybean oilAn oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency.
Safflower oilNo approved therapeutic indications.
Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
Rotavirus vaccineRotarix is indicated for prevention of rotavirus gastroenteritis caused by G1, G3, G4, and G9 types in infants aged 6-24 weeks [FDA Label]. Rotateq is indicated for the prevention of...
Rabies virus inactivated antigen, ARabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the...
Varicella zoster vaccine (live/attenuated)Zostavax vaccine is indicated for the prevention of herpes zoster (shingles) in immunocompetent adults aged 50 years and older. Varivax vaccine is indicated for active immunization for the prevention of...
House dustAn extract from House dust used in allergy testing.
Phleum pratense pollenAn extract from Phleum pratense pollen used in allergy testing.
AcaciaAn extract from Acacia used in allergy testing.
Karaya gumAn extract from Karaya gum used in allergy testing.
Clostridium tetani toxoid antigen (formaldehyde inactivated)Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention...
Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)Not Annotated
TragacanthAn extract from Tragacanth used in allergy testing.
CloveAn extract from Clove used in allergy testing.
Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)Not Annotated
Yellow fever vaccineYellow Fever Vaccine is indicated for active immunization for the prevention of yellow fever in persons 9 months of age and older in the following categories: Persons Living in or...
CarobAn extract from Carob used in allergy testing.
Hepatitis A VaccineAn inactivated vaccine against infection with the Hepatitis A virus.
Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects...
Anthrax vaccineA vaccine indicated for the pre- and post-exposure prophylaxis treatment of diseases caused by exposure to Bacillus anthracis
Coal tarRelieving itching, irritation, redness, dryness, scaling, and flaking of the skin caused by psoriasis, seborrhea, or eczema.
Plantago seedAn ingredient used in a variety of natural health products.
Castor oilAn ingredient used in a variety of natural health products.
Eucalyptus oilAn ingredient used in a variety of natural health products.
TurpentineA medication used to treat minor aches and pains of muscles and joints.
OpiumA medication used to treat moderate to severe pain.
Capsicum oleoresinA medication used to treat minor aches and pains of muscles and joints.
Silicon dioxideAn ingredient found in a variety of supplements and vitamins.
PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
RosinAn extract from Rosin used in allergy testing.
Sesame oilSesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic...
Peppermint oilAn ingredient used in a variety of natural health products and is not an approved medication.
Tea tree oilIndicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications.
Benzoin resinA compound used to protect small wounds or canker sores.
Tolu balsamNot Annotated
Borage oilBorage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as...
Clove oilClove oil is primarily indicated in conditions like colic, flatulence, and toothache .
Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical...
Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
MyrrhFDA approved only for use in food. Historically used for indigestion, ulcers, colds, cough, asthma, bronchial congestion, arthritic pain, cancer, leprosy, and syphilis. It is also used orally as a...
Human varicella-zoster immune globulinA solution of antibodies used for post exposure prophylaxis of varicella infections in high risk populations, as well as to reduce the severity of infections.
Hepatitis B Vaccine (Recombinant)A solution of Hepatitis B surface antigen used to immunize patients against Hepatitis B.
BombesinBombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and...
Carbon blackCarbon black has been used in trials studying Atopic Hypersensitivity and Hypersensitivity, Immediate.
TecemotideTecemotide has been used in trials studying the treatment of Prostate Cancer and Carcinoma, Non-Small-Cell Lung.
AviscumineCy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy).
BCG vaccineA vaccine indicated in the prevention of tuberculosis and the treatment of non-invasive urothelial bladder cancer.
NeosaxitoxinNeosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic).
LevomenolLevomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain...
Vitex agnus-castus fruit extractA herbal product used to treat an irregular menstrual period, premenstrual symptoms, and mastodynia
Horse chestnutA plant extract indicated in the treatment of venous insufficiency and other disorders caused by poor circulation.
ValerianA plant used in some non-prescription natural health products.
IpecacAn emetic agent used to induce vomiting in poisoning.
Guar gumNot Annotated
Axicabtagene ciloleucelA CAR T-cell therapy used to treat adults with large B-cell lymphomas and follicular lymphoma.
Remestemcel-LIndicated for in the management of acute Graft versus Host Disease (aGvHD) in pediatric patients. Acute GvHD should be refractory to treatment with systemic corticosteroid therapy and/or other immunosuppressive agents....
Black cohoshA herbal product indicated in the symptomatic treatment of menopause.
Typhoid vaccineA vaccine used to prevent typhoid.
BilberryNot Annotated
Echinacea purpurea flowering topNot Annotated
Echinacea purpureaNot Annotated
Bos taurus gallstoneBos taurus gallstone is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Centella asiaticaCentella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Calendula officinalis flowerCalendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
RosemaryRosemary is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
TurmericTurmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Phellinus linteus myceliumPhellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Panax ginseng wholePanax ginseng whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Rehmannia glutinosa rootRehmannia glutinosa root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Arnica montanaArnica montana is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
EleutheroEleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Panax notoginseng rootPanax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Tribulus terrestris fruitTribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Green tea leafGreen tea leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Meadowfoam seed oilMeadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Argan oilArgan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Tangerine peelTangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
AmberAmber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Chamaemelum nobile flowerChamaemelum nobile flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Sunflower oilSunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Nelumbo nucifera flowerNelumbo nucifera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Bergamot oilBergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Angelica sinensis rootAngelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Salvia miltiorrhiza rootSalvia miltiorrhiza root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Prunus armeniaca seedPrunus armeniaca seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Arnica montana flowerArnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Forsythia suspensa fruitForsythia suspensa fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Platycodon grandiflorus rootPlatycodon grandiflorus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
ChamomileChamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Saw palmettoSaw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Scutellaria baicalensis rootScutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Milk thistleMilk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Palm oilPalm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Vibrio cholerae CVD 103-HgR strain live antigenA live, attenuated vaccine indicated for active immunization against disease caused by Vibrio cholerae serogroup O1.
Sophora flavescens rootNot Annotated
Lavender oilNot Annotated
Plantago ovata seedA plant extract indicated in the treatment of occasional constipation.
Sambucus nigra flowerNot Annotated
Willow barkNot Annotated
Smallpox (Vaccinia) Vaccine, LiveThe live antigen of the New York City Board of Health strain of Vaccinia is indicated (within the ACAM2000 formulation) for active immunization against smallpox disease in patients determined to...
Olea europaea leafNot Annotated
Polygala senega rootNot Annotated
Dengue tetravalent vaccine, liveNot Annotated
Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females).
BelapectinBelapectin is under investigation in clinical trial NCT02575404 (GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients).
ChlorotoxinChlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
Pertussis vaccinePertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
TozuleristideTozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Yersinia pestis 195/p antigen (formaldehyde inactivated)Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine).
Onasemnogene abeparvovecA gene therapy used to treat neonatal and infant patients with spinal muscular atrophy caused by bi-allelic mutations in the survival motor neuron 1 (SMN1) gene.
beta-Apopicropodophyllinbeta-Apopicropodophyllin is a component of the freshwater plant Micranthemum umbrosum.
AstraZeneca COVID-19 VaccineA two-dose replication-deficient adenovirus vector vaccine used to prevent COVID-19 caused by SARS-CoV-2.
INO-4800INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that...
BNT162b1 SARS-CoV-2 VaccineBNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding...
TozinameranAn mRNA vaccine for the prevention of COVID-19 caused by the SARS-CoV-2 virus.
Anise oilNot Annotated
SolcoserylA component of calf blood indicated to improve healing of the skin, mouth, or cornea.
VPM1002The bacille Calmette-Guérin (BCG) vaccine protects against severe extrapulmonary forms of tuberculosis (TB) but does not adequately protect against pulmonary TB -- the most prevalent form of TB. This recombinant...
BBIBP-CorVBBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in...
NuvaxovidA recombinant spike (S) protein vaccine for the prevention of COVID-19 caused by SARS-CoV-2.
LecithinFatty substances commonly found in nutritional supplements.
Hawthorn leaf with flowerNot Annotated
IMM-101IMM-101 is a heat-inactivated immune-activating mycobacterial product. It has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma[A220013,A220018,A220023]. Studies...
Janssen COVID-19 VaccineAn adenovirus-based vaccine used for active immunization against COVID-19 caused by SARS-CoV-2 infection.
Senna leafA stimulant laxative indicated in the treatment of occasional constipation.
Cajuput oilAn ingredient used in topical products for mild analgesia.
Bizalimogene ralaplasmidBizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related Anal or Anal/peri-anal, High Grade...
PidacmeranPidacmeran is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).
BNT-162A1BNT-162A1 is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).
VidPrevtyn BetaA recombinant, adjuvanted DNA vaccine given as a booster dose to prevent COVID-19.
EpiVacCoronaEpiVacCorona Vaccine, developed by the Vektor State Research Center of Virology and Biotechnology in Russia, is based on peptide-antigens that facilitate immunity to the SARS-CoV-2 virus . It is currently...
OM85OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
Gentiana lutea extractA medication used to treat bloating and gas.
Wheat germ oilNot Annotated
Pygeum africanum barkA plant extract indicated in the symptomatic treatment of prostatic hypertrophy.
FrankincenseNot Annotated
Paeonia lactiflora rootNot Annotated
Citronella oilNot Annotated
Vitis vinifera seedNot Annotated
Thyme oilNot Annotated
Gastrodia elata wholeNot Annotated
Juniper tarNot Annotated
Birch bark extractA herbal medicinal product used to treat partial thickness wounds.
VirulizinNot Available
Algenpantucel-LNot Annotated
LeuvectinLeuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE).
Onamelatucel-LNot Annotated
Gemogenovatucel-TGemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine. Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2. Gemogenovatucel-T is being...
Incomplete Freund's adjuvantNot Annotated
GI-6207Not Annotated
PicibanilNot Annotated
TrastuzumabA monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers.
PicrotoxinUsed internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
AndrographolideInvestigated for use/treatment in ulcerative colitis.
Liquidambar styraciflua resinNot Annotated
Glycyrrhiza glabraGlycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Ephedra sinica stemNot Annotated
Modified vaccinia ankaraA live, non-replicating orthopoxvirus vaccine used to prevent smallpox, monkeypox, and other diseases caused by vaccinia virus.
SCB-2019SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The...
CoronaVacCoronaVac, previously known as PiCoVacc, is a SARS-CoV-2 purified, inactivated, and adsorbed vaccine candidate developed by SinoVac Biotech Corporation . It was developed by propagating the SARS-CoV-2 CN2 strain inside...
CVnCoV VaccineThe CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate...
BBV152BBV152 is a vaccine candidate created by the Indian Council of Medical Research (ICMR). The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and...
Rocakinogene sifuplasmidRocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma (GBM)).
CoVac-1Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein . It is...
UB-612The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components . The vaccine...
Betibeglogene autotemcelA hematopoietic stem cell-based gene therapy used in the treatment of β-thalassemia in adult and pediatric patients who require regular red blood cell transfusions.
FamtozinameranA component of a bivalent COVID-19 mRNA vaccine encoding the viral spike protein of Omicron variant lineages BA.4 and BA.5.
Nix-0699Not Annotated
TubimodNot Available
RemuneNot Available
GsMtx-4GsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity.
Mycobacterium w. VaccineThe Mycobacterium w (M.w) vaccine is a heat-killed suspension derived from a non-pathogenic mycobacterium: mycobacterium indicus pranii. As an immunotherapy, M.w is used against leprosy; the compound also shares antigens...
Drugs & Drug Targets
DrugTargetType
ZiconotideVoltage-dependent N-type calcium channel subunit alpha-1Btarget
ZiconotideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
SennosidesReverse transcriptase/RNaseHtarget
SennosidesAquaporin-3target
Ginkgo bilobaCytochrome P450 2C9enzyme
Ginkgo bilobaPhospholipase A2, membrane associatedtarget
Ginkgo bilobaSodium-dependent noradrenaline transportertarget
Ginkgo bilobaGlycine receptor subunit alpha-1target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit alpha-1target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit beta-2target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit gamma-2target
Ginkgo bilobaCytochrome P450 3A4enzyme
Ginkgo bilobaAmine oxidase [flavin-containing] Atarget
Ginkgo bilobaNitric oxide synthase, inducibletarget
Ginkgo bilobaCytochrome P450 1B1enzyme
Ginkgo bilobaCytochrome P450 1A1enzyme
Ginkgo bilobaCytochrome P450 1A2enzyme
Talimogene laherparepvecHeparan sulfatetarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget
Talimogene laherparepvecDNA polymerase catalytic subunittarget
AncrodFibrinogen alpha chaintarget
SerotoninSolute carrier family 22 member 2transporter
SerotoninSodium-dependent serotonin transportertarget
Serotonin5-hydroxytryptamine receptor 2Atarget
Serotonin5-hydroxytryptamine receptor 3Atarget
Serotonin5-hydroxytryptamine receptor 3Btarget
SerotoninSynaptic vesicular amine transportertarget
MenotropinsFollicle-stimulating hormone receptortarget
MenotropinsLutropin-choriogonadotropic hormone receptortarget
Botulinum toxin type BVesicle-associated membrane protein 1target
Botulinum toxin type BVesicle-associated membrane protein 2target
Botulinum toxin type BSynaptotagmin-2target
Insulin glargineInsulin receptortarget
Insulin glargineInsulin-like growth factor 1 receptortarget
Insulin glargineCytochrome P450 1A2enzyme
InfliximabTumor necrosis factortarget
PancrelipaseDietary fattarget
PancrelipaseDietary proteintarget
PancrelipaseDietary starchtarget
Antithymocyte immunoglobulin (rabbit)T-cell surface glycoprotein CD1atarget
Antithymocyte immunoglobulin (rabbit)Major histocompatibility complex class I-related gene proteintarget
Antithymocyte immunoglobulin (rabbit)Integrin alpha-Ltarget
Antithymocyte immunoglobulin (rabbit)T-lymphocyte activation antigen CD86target
Antithymocyte immunoglobulin (rabbit)Low affinity immunoglobulin gamma Fc region receptor II-btarget
Antithymocyte immunoglobulin (rabbit)T-cell surface glycoprotein CD4target
Antithymocyte immunoglobulin (rabbit)Integrin beta-1target
Antithymocyte immunoglobulin (rabbit)Integrin alpha-Vtarget
Antithymocyte immunoglobulin (rabbit)Integrin beta-3target
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
QuinidineSerum albumincarrier
St. John's WortP-glycoprotein 1transporter
St. John's WortCytochrome P450 3A4enzyme
St. John's WortCytochrome P450 2D6enzyme
St. John's WortCytochrome P450 2C19enzyme
Ephedra sinica rootSodium-dependent dopamine transportertarget
Ephedra sinica rootSynaptic vesicular amine transportertarget
Ephedra sinica rootChromaffin granule amine transportertarget
Ephedra sinica rootSodium-dependent noradrenaline transportertarget
Ephedra sinica rootAmine oxidase [flavin-containing] Atarget
Ephedra sinica rootAmine oxidase [flavin-containing] Btarget
Ephedra sinica rootSodium-dependent serotonin transportertarget
Ephedra sinica rootAlpha-2A adrenergic receptortarget
Ephedra sinica rootAlpha-2B adrenergic receptortarget
Ephedra sinica rootAlpha-2C adrenergic receptortarget
Ephedra sinica rootBeta-1 adrenergic receptortarget
Ephedra sinica rootBeta-2 adrenergic receptortarget
Ephedra sinica rootBeta-3 adrenergic receptortarget
GinsengInterleukin-6target
GinsengProstaglandin G/H synthase 2target
GinsengAryl hydrocarbon receptortarget
BufotenineAmine oxidase [flavin-containing] Aenzyme
CamphorCamphor 5-monooxygenasetarget
CamphorTransient receptor potential cation channel subfamily V member 1target
CamphorTransient receptor potential cation channel subfamily V member 3target
CamphorTransient receptor potential cation channel subfamily A member 1target
CamphorTransient receptor potential cation channel subfamily M member 8target
RindopepimutEpidermal growth factor receptortarget
Neovastat72 kDa type IV collagenasetarget
NeovastatMatrix metalloproteinase-9target
NeovastatMacrophage metalloelastasetarget
LLL-3348Interleukin-10target
TG4010Mucin-1target
TG4010Interleukin-2target
Sipuleucel-TProstatic acid phosphatasetarget
Chorionic Gonadotropin (Human)Lutropin-choriogonadotropic hormone receptortarget
Soybean oilPeroxisome proliferator-activated receptor alphatarget
Hepatitis A VaccineB-lymphocytestarget
Castor oilProstaglandin E2 receptor EP3 subtypetarget
Castor oilProstaglandin E2 receptor EP4 subtypetarget
TurpentineMitogen-activated protein kinase 1target
OpiumDelta-type opioid receptortarget
OpiumKappa-type opioid receptortarget
OpiumMu-type opioid receptortarget
OpiumSerum albumincarrier
OpiumBeta-2-microglobulincarrier
OpiumCytochrome P450 2D6enzyme
OpiumCytochrome P450 3A4enzyme
Capsicum oleoresinTransient receptor potential cation channel subfamily V member 1target
Silicon dioxideMacrophage receptor MARCOtarget
Peppermint oilCytochrome P450 1A2enzyme
Peppermint oilCytochrome P450 3A4enzyme
Clove oilVascular cell adhesion protein 1target
Clove oilC-X-C motif chemokine 10target
Clove oilCollagen alpha-1(I) chaintarget
Clove oilGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
Evening primrose oilElongation of very long chain fatty acids protein 5enzyme
Evening primrose oilFatty acid desaturase 1enzyme
Evening primrose oilFatty acid desaturase 2enzyme
MyrrhBile acid receptortarget
MyrrhCytochrome P450 3A Subfamilyenzyme
MyrrhNuclear receptor subfamily 1 group I member 2target
MyrrhPeroxisome proliferator-activated receptor alphatarget
LevomenolSolute carrier organic anion transporter family member 1B1transporter
LevomenolSolute carrier organic anion transporter family member 1B3transporter
IpecacCytochrome P450 2D6enzyme
IpecacCytochrome P450 3A4enzyme
Axicabtagene ciloleucelB-lymphocyte antigen CD19target
Black cohoshCytochrome P450 3A4enzyme
Black cohoshCytochrome P450 3A2enzyme
Black cohoshCytochrome P450 1A2enzyme
Black cohoshCytochrome P450 2C9enzyme
Black cohoshCytochrome P450 2D6enzyme
Birch bark extractCytochrome P450 2C8enzyme
Birch bark extractCytochrome P450 3A Subfamilyenzyme
TrastuzumabReceptor tyrosine-protein kinase erbB-2target
PicrotoxinGamma-aminobutyric acid receptor subunit rho-1target
PicrotoxinGamma-aminobutyric acid receptor subunit alpha-1target
PicrotoxinGlycine receptor subunit alpha-2target
PicrotoxinGlycine receptor subunit alpha-3target
PicrotoxinCytochrome P450 1A1enzyme
PicrotoxinGlutamine synthetaseenzyme
PicrotoxinGlycine receptor subunit alpha-1target
AndrographolideTumor necrosis factortarget
AndrographolideInterleukin-1 betatarget
AndrographolideInterleukin-6target
AndrographolideNuclear factor NF-kappa-B p100 subunittarget
AndrographolideNuclear factor NF-kappa-B p105 subunittarget
Betibeglogene autotemcelAlpha globintarget