Typhoid Vaccine Live

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Typhoid Vaccine Live
Accession Number
DB11050
Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Attenuated
Description

Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain Salmonella typhi Ty21a. The vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by Salmonella typhi by inducing a local immune response in the intestinal tract.

Synonyms
  • Salmonella enterica subsp. enterica serovar typhi
  • Salmonella typhi Ty21a live antigen
  • Typhoid vaccine (salmonella typhi Ty21a)
  • Typhoid Vaccine Live Ty21a
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
VivotifCapsule, delayed release10000000000 [CFU]OralPaxvax Berna Gmbh1993-01-01Not applicableCanada
VivotifCapsule, coated6000000000 [CFU]/1OralPaxvax Berna Gmbh1992-03-16Not applicableUs
VivotifCapsule, coated6000000000 [CFU]/1OralA-S Medication Solutions1992-03-16Not applicableUs
VivotifCapsule, coated2 [CFU]/1[CFU]OralA-S Medication Solutions1992-03-16Not applicableUs
Vivotif LPowderOralBerna Biotech Ltd1997-11-012015-11-01Canada
Additional Data Available
  • Application Number
    Application Number

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  • Product Code
    Product Code

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Categories
UNII
0MZI008M96
CAS number
Not Available

Pharmacology

Indication
Not Available
Associated Conditions
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
2-MethoxyethanolThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin AThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
AbacavirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Abacavir.
AbataceptThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Abatacept.
AbetimusThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Abetimus.
ActeosideThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Acteoside.
AcyclovirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Acyclovir.
AdafosbuvirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Adafosbuvir.
AdalimumabThe risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Adalimumab.
AdefovirThe therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Adefovir.
Additional Data Available
  • Extended Description
    Extended Description

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  • Severity
    Severity

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  • Evidence Level
    Evidence Level

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  • Action
    Action

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Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Substance
347911093
AHFS Codes
  • 80:12.00 — Vaccines

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0RecruitingBasic ScienceInflammatory Reaction / Intestinal Permeability / Salmonella Typhi Infection / Vaccines1
2Active Not RecruitingPreventionSalmonella Typhi Infection1
2TerminatedTreatmentUlcerative Colitis1
4Active Not RecruitingBasic ScienceFlu caused by Influenza / Healthy Adults / Hepatitis A / Salmonella Typhi Infection1
4RecruitingBasic ScienceRisk Reduction1
4RecruitingBasic ScienceTyphoid Vaccination1
4RecruitingBasic ScienceTyphoid and/or Cholera Vaccination1
4RecruitingPreventionHealthy Volunteers1
Not AvailableCompletedNot AvailableSalmonella Typhi Infection1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
Capsule, coatedOral2 [CFU]/1[CFU]
Capsule, coatedOral6000000000 [CFU]/1
Capsule, delayed releaseOral10000000000 [CFU]
PowderOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on December 01, 2015 13:05 / Updated on November 14, 2019 20:00