Eltanolone

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Eltanolone
Accession Number
DB12308
Type
Small Molecule
Groups
Investigational
Description

Eltanolone is under investigation in clinical trial NCT02603926 (Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone).

Structure
Thumb
Synonyms
  • Pregnanolone
External IDs
KABI 2213 / KABI-2213 / NSC-82867 / SKF-6455
Categories
UNII
BXO86P3XXW
CAS number
128-20-1
Weight
Average: 318.501
Monoisotopic: 318.255880335
Chemical Formula
C21H34O2
InChI Key
AURFZBICLPNKBZ-YZRLXODZSA-N
InChI
InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15-,16+,17-,18+,19+,20+,21-/m1/s1
IUPAC Name
1-[(1S,2S,5R,7R,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]ethan-1-one
SMILES

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Eltanolone.Experimental
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Eltanolone.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Eltanolone.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Eltanolone.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Eltanolone.Approved, Investigational
AlaproclateThe risk or severity of adverse effects can be increased when Eltanolone is combined with Alaproclate.Experimental
AlfaxaloneThe risk or severity of adverse effects can be increased when Alfaxalone is combined with Eltanolone.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Eltanolone.Approved, Illicit
AllopregnanoloneThe risk or severity of adverse effects can be increased when Allopregnanolone is combined with Eltanolone.Investigational
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Eltanolone.Experimental, Illicit
AlphaprodineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Alphaprodine.Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Eltanolone.Approved, Illicit, Investigational
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Eltanolone.Approved, Investigational
AmitriptylineThe risk or severity of adverse effects can be increased when Amitriptyline is combined with Eltanolone.Approved
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with Eltanolone.Approved, Illicit
AmoxapineThe risk or severity of adverse effects can be increased when Amoxapine is combined with Eltanolone.Approved
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Eltanolone.Experimental
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with Eltanolone.Approved, Investigational
ArticaineThe risk or severity of adverse effects can be increased when Articaine is combined with Eltanolone.Approved
AsenapineThe risk or severity of adverse effects can be increased when Asenapine is combined with Eltanolone.Approved
AzaperoneThe risk or severity of adverse effects can be increased when Azaperone is combined with Eltanolone.Investigational, Vet Approved
AzelastineEltanolone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Eltanolone.Approved
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with Eltanolone.Illicit
BenperidolThe risk or severity of adverse effects can be increased when Eltanolone is combined with Benperidol.Approved, Investigational
BenzocaineThe risk or severity of adverse effects can be increased when Benzocaine is combined with Eltanolone.Approved, Investigational
Benzyl alcoholThe risk or severity of adverse effects can be increased when Benzyl alcohol is combined with Eltanolone.Approved
BrexpiprazoleThe risk or severity of adverse effects can be increased when Brexpiprazole is combined with Eltanolone.Approved, Investigational
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Eltanolone.Approved, Illicit, Investigational
BromisovalThe risk or severity of adverse effects can be increased when Eltanolone is combined with Bromisoval.Experimental
BromperidolThe risk or severity of adverse effects can be increased when Eltanolone is combined with Bromperidol.Approved, Investigational
BrompheniramineThe risk or severity of adverse effects can be increased when Brompheniramine is combined with Eltanolone.Approved
BrotizolamThe risk or severity of adverse effects can be increased when Brotizolam is combined with Eltanolone.Approved, Investigational, Withdrawn
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Eltanolone.Approved, Investigational
BuprenorphineEltanolone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Eltanolone.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Eltanolone.Approved, Illicit
ButacaineThe risk or severity of adverse effects can be increased when Butacaine is combined with Eltanolone.Vet Approved
ButalbitalThe risk or severity of adverse effects can be increased when Butalbital is combined with Eltanolone.Approved, Illicit
ButambenThe risk or severity of adverse effects can be increased when Butamben is combined with Eltanolone.Approved, Withdrawn
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Eltanolone.Approved, Illicit
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Eltanolone.Approved, Illicit, Vet Approved
CanertinibThe risk or severity of adverse effects can be increased when Canertinib is combined with Eltanolone.Investigational
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with Eltanolone.Approved, Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Carbinoxamine is combined with Eltanolone.Approved
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Eltanolone.Illicit, Investigational, Vet Approved
CarisoprodolThe risk or severity of adverse effects can be increased when Carisoprodol is combined with Eltanolone.Approved
CetirizineThe risk or severity of adverse effects can be increased when Cetirizine is combined with Eltanolone.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Eltanolone.Approved, Illicit, Investigational, Vet Approved
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Eltanolone.Approved, Illicit, Investigational
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with Eltanolone.Approved, Investigational, Withdrawn
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with Eltanolone.Approved
ChlorphenamineThe risk or severity of adverse effects can be increased when Chlorphenamine is combined with Eltanolone.Approved
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Eltanolone.Approved, Investigational, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Eltanolone.Approved, Investigational, Withdrawn
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Eltanolone.Approved
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Eltanolone.Approved, Vet Approved
CitalopramThe risk or severity of adverse effects can be increased when Eltanolone is combined with Citalopram.Approved
ClemastineThe risk or severity of adverse effects can be increased when Clemastine is combined with Eltanolone.Approved, Investigational
ClidiniumThe risk or severity of adverse effects can be increased when Clidinium is combined with Eltanolone.Approved
ClobazamThe risk or severity of adverse effects can be increased when Clobazam is combined with Eltanolone.Approved, Illicit
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Eltanolone.Investigational
ClomipramineThe risk or severity of adverse effects can be increased when Clomipramine is combined with Eltanolone.Approved, Investigational, Vet Approved
ClonazepamThe risk or severity of adverse effects can be increased when Clonazepam is combined with Eltanolone.Approved, Illicit
ClonidineThe risk or severity of adverse effects can be increased when Clonidine is combined with Eltanolone.Approved
ClopenthixolThe risk or severity of adverse effects can be increased when Eltanolone is combined with Clopenthixol.Experimental
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Eltanolone.Approved, Illicit
ClothiapineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Clothiapine.Experimental
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Eltanolone.Approved
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Eltanolone.Approved, Illicit
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Eltanolone.Approved, Illicit
CyclizineThe risk or severity of adverse effects can be increased when Cyclizine is combined with Eltanolone.Approved
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Eltanolone.Approved
CyclopropaneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Cyclopropane.Experimental
CyproheptadineThe risk or severity of adverse effects can be increased when Cyproheptadine is combined with Eltanolone.Approved
DantroleneThe risk or severity of adverse effects can be increased when Dantrolene is combined with Eltanolone.Approved, Investigational
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Eltanolone.Approved
DapoxetineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Dapoxetine.Investigational
DeramciclaneThe risk or severity of adverse effects can be increased when Deramciclane is combined with Eltanolone.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Eltanolone.Approved
DesipramineThe risk or severity of adverse effects can be increased when Desipramine is combined with Eltanolone.Approved, Investigational
DesloratadineThe risk or severity of adverse effects can be increased when Desloratadine is combined with Eltanolone.Approved, Investigational
DesvenlafaxineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Desvenlafaxine.Approved, Investigational
DetomidineThe risk or severity of adverse effects can be increased when Detomidine is combined with Eltanolone.Vet Approved
DexbrompheniramineThe risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Eltanolone.Approved
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Eltanolone.Approved, Vet Approved
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Eltanolone.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Eltanolone.Approved, Illicit, Investigational, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Eltanolone.Approved, Investigational
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Eltanolone.Approved, Illicit, Investigational, Vet Approved
Diethyl etherThe risk or severity of adverse effects can be increased when Eltanolone is combined with Diethyl ether.Experimental
DifenoxinThe risk or severity of adverse effects can be increased when Difenoxin is combined with Eltanolone.Approved, Illicit
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Eltanolone.Approved, Illicit
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Eltanolone.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Eltanolone.Experimental, Illicit
DimenhydrinateThe risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Eltanolone.Approved
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Eltanolone.Approved, Investigational
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Eltanolone.Approved, Illicit
DixyrazineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Dixyrazine.Experimental
DoramectinThe risk or severity of adverse effects can be increased when Doramectin is combined with Eltanolone.Vet Approved
DoxepinThe risk or severity of adverse effects can be increased when Doxepin is combined with Eltanolone.Approved, Investigational
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved, Vet Approved
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Eltanolone.Experimental
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved, Illicit
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved, Vet Approved
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Eltanolone.Experimental, Illicit
DuloxetineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Eltanolone.Approved
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with Eltanolone.Experimental, Illicit
EcopipamThe risk or severity of adverse effects can be increased when Ecopipam is combined with Eltanolone.Investigational
EfavirenzThe risk or severity of adverse effects can be increased when Efavirenz is combined with Eltanolone.Approved, Investigational
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Eltanolone.Approved, Investigational, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Entacapone is combined with Eltanolone.Approved, Investigational
EscitalopramThe risk or severity of adverse effects can be increased when Eltanolone is combined with Escitalopram.Approved, Investigational
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Eltanolone.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Eltanolone.Approved, Investigational
EthanolEltanolone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.Approved
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Eltanolone.Approved, Illicit, Withdrawn
EthosuximideThe risk or severity of adverse effects can be increased when Ethosuximide is combined with Eltanolone.Approved
EthotoinThe risk or severity of adverse effects can be increased when Ethotoin is combined with Eltanolone.Approved
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Eltanolone.Withdrawn
Ethyl chlorideThe risk or severity of adverse effects can be increased when Eltanolone is combined with Ethyl chloride.Approved, Experimental, Investigational
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Eltanolone.Approved, Illicit
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Eltanolone.Approved, Illicit
EtidocaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Eltanolone.Approved
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Eltanolone.Investigational, Withdrawn
EtizolamThe risk or severity of adverse effects can be increased when Etizolam is combined with Eltanolone.Approved
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Eltanolone.Approved
EtoperidoneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Etoperidone.Withdrawn
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with Eltanolone.Illicit, Vet Approved
EzogabineThe risk or severity of adverse effects can be increased when Ezogabine is combined with Eltanolone.Approved, Investigational
FelbamateThe risk or severity of adverse effects can be increased when Felbamate is combined with Eltanolone.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Eltanolone.Approved, Illicit, Withdrawn
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Eltanolone.Approved, Illicit, Investigational, Vet Approved
FexofenadineThe risk or severity of adverse effects can be increased when Fexofenadine is combined with Eltanolone.Approved, Investigational
FlibanserinThe risk or severity of adverse effects can be increased when Flibanserin is combined with Eltanolone.Approved, Investigational
FluanisoneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Fluanisone.Experimental
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Eltanolone.Approved, Illicit
FlunarizineThe risk or severity of adverse effects can be increased when Flunarizine is combined with Eltanolone.Approved
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Eltanolone.Approved, Illicit
FluoxetineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Fluoxetine.Approved, Vet Approved
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Eltanolone.Approved, Investigational, Withdrawn
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Eltanolone.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Eltanolone.Approved, Illicit, Investigational
FluspirileneThe risk or severity of adverse effects can be increased when Fluspirilene is combined with Eltanolone.Approved, Investigational
Fluticasone propionateThe risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Eltanolone.Approved
FluvoxamineThe risk or severity of adverse effects can be increased when Fluvoxamine is combined with Eltanolone.Approved, Investigational
FosphenytoinThe risk or severity of adverse effects can be increased when Fosphenytoin is combined with Eltanolone.Approved, Investigational
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Eltanolone.Approved, Illicit, Investigational
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Eltanolone.Approved, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Gabapentin Enacarbil is combined with Eltanolone.Approved, Investigational
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Eltanolone.Approved, Illicit, Investigational
GepironeThe risk or severity of adverse effects can be increased when Gepirone is combined with Eltanolone.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Eltanolone.Approved, Illicit
GuanfacineThe risk or severity of adverse effects can be increased when Guanfacine is combined with Eltanolone.Approved, Investigational
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Eltanolone.Approved, Illicit, Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Eltanolone.Approved
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Eltanolone.Approved, Vet Approved
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Eltanolone.Approved, Illicit, Investigational
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with Eltanolone.Approved
HydrocodoneEltanolone may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.Approved, Illicit
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Eltanolone.Approved, Illicit
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved
IloperidoneThe risk or severity of adverse effects can be increased when Iloperidone is combined with Eltanolone.Approved
ImipramineThe risk or severity of adverse effects can be increased when Imipramine is combined with Eltanolone.Approved
IndalpineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Indalpine.Investigational, Withdrawn
IndiplonThe risk or severity of adverse effects can be increased when Eltanolone is combined with Indiplon.Investigational
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Eltanolone.Approved, Vet Approved
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Eltanolone.Approved, Vet Approved
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Eltanolone.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Eltanolone.Approved, Investigational
LamotrigineThe risk or severity of adverse effects can be increased when Lamotrigine is combined with Eltanolone.Approved, Investigational
LevetiracetamThe risk or severity of adverse effects can be increased when Levetiracetam is combined with Eltanolone.Approved, Investigational
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Eltanolone.Approved, Investigational
LevocabastineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Levocabastine.Approved, Investigational
LevocetirizineThe risk or severity of adverse effects can be increased when Levocetirizine is combined with Eltanolone.Approved
LevodopaThe risk or severity of adverse effects can be increased when Levodopa is combined with Eltanolone.Approved
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Eltanolone.Approved, Investigational
LevomilnacipranThe risk or severity of adverse effects can be increased when Eltanolone is combined with Levomilnacipran.Approved, Investigational
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Eltanolone.Approved
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with Eltanolone.Approved, Vet Approved
LithiumThe risk or severity of adverse effects can be increased when Lithium is combined with Eltanolone.Approved
LofentanilThe risk or severity of adverse effects can be increased when Lofentanil is combined with Eltanolone.Illicit
LoprazolamThe risk or severity of adverse effects can be increased when Eltanolone is combined with Loprazolam.Experimental
LoratadineThe risk or severity of adverse effects can be increased when Loratadine is combined with Eltanolone.Approved, Investigational
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Eltanolone.Approved
LormetazepamThe risk or severity of adverse effects can be increased when Eltanolone is combined with Lormetazepam.Approved
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Eltanolone.Approved
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Eltanolone.Approved, Investigational
Magnesium sulfateThe therapeutic efficacy of Eltanolone can be increased when used in combination with Magnesium sulfate.Approved, Investigational, Vet Approved
MaprotilineThe risk or severity of adverse effects can be increased when Maprotiline is combined with Eltanolone.Approved, Investigational
MebicarThe risk or severity of adverse effects can be increased when Eltanolone is combined with Mebicar.Experimental
MeclizineThe risk or severity of adverse effects can be increased when Meclizine is combined with Eltanolone.Approved
MedazepamThe risk or severity of adverse effects can be increased when Eltanolone is combined with Medazepam.Experimental
MedetomidineThe risk or severity of adverse effects can be increased when Medetomidine is combined with Eltanolone.Vet Approved
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Eltanolone.Approved, Nutraceutical, Vet Approved
MelperoneThe risk or severity of adverse effects can be increased when Melperone is combined with Eltanolone.Approved, Investigational
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Eltanolone.Approved, Vet Approved
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Eltanolone.Approved, Illicit
MeptazinolThe risk or severity of adverse effects can be increased when Eltanolone is combined with Meptazinol.Experimental
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Eltanolone.Approved, Investigational
MetaxaloneThe risk or severity of adverse effects can be increased when Metaxalone is combined with Eltanolone.Approved
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Eltanolone.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Eltanolone.Approved, Illicit
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Eltanolone.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Eltanolone.Illicit, Withdrawn
MethocarbamolThe risk or severity of adverse effects can be increased when Methocarbamol is combined with Eltanolone.Approved, Vet Approved
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Eltanolone.Approved
MethotrimeprazineEltanolone may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved, Investigational
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Eltanolone.Approved, Investigational, Vet Approved
MethsuximideThe risk or severity of adverse effects can be increased when Methsuximide is combined with Eltanolone.Approved
MethylecgonineThe risk or severity of adverse effects can be increased when Methylecgonine is combined with Eltanolone.Experimental
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Eltanolone.Approved
MetyrosineEltanolone may increase the sedative activities of Metyrosine.Approved
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Eltanolone.Approved, Illicit
MilnacipranThe risk or severity of adverse effects can be increased when Eltanolone is combined with Milnacipran.Approved, Investigational
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved, Investigational
MirtazapineEltanolone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Eltanolone.Approved
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Eltanolone.Approved, Investigational
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved, Investigational
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Eltanolone.Approved
NefazodoneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Nefazodone.Approved, Withdrawn
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Eltanolone.Approved
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Eltanolone.Approved, Vet Approved
NorfluraneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Norflurane.Approved, Investigational
NormethadoneThe risk or severity of adverse effects can be increased when Normethadone is combined with Eltanolone.Approved, Illicit
NortriptylineThe risk or severity of adverse effects can be increased when Nortriptyline is combined with Eltanolone.Approved
OlanzapineThe risk or severity of adverse effects can be increased when Olanzapine is combined with Eltanolone.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Eltanolone.Approved
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Eltanolone.Approved
OpiumThe risk or severity of adverse effects can be increased when Opium is combined with Eltanolone.Approved, Illicit
OrphenadrineEltanolone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Eltanolone.Investigational
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Eltanolone.Approved
OxethazaineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Oxethazaine.Approved, Investigational
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Eltanolone.Approved
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Eltanolone.Approved, Investigational
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Eltanolone.Approved, Illicit, Investigational
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with Eltanolone.Approved, Investigational, Vet Approved
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with Eltanolone.Approved
ParaldehydeEltanolone may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved, Investigational
ParoxetineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Paroxetine.Approved, Investigational
PenfluridolThe risk or severity of adverse effects can be increased when Eltanolone is combined with Penfluridol.Experimental
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Eltanolone.Approved, Vet Approved
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Eltanolone.Approved, Investigational, Vet Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved
PerazineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Perazine.Approved, Investigational
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Eltanolone.Approved
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Eltanolone.Approved
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Eltanolone.Approved
PhenazocineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Phenazocine.Experimental
PhenibutThe risk or severity of adverse effects can be increased when Eltanolone is combined with Phenibut.Experimental
PhenobarbitalThe risk or severity of adverse effects can be increased when Phenobarbital is combined with Eltanolone.Approved, Investigational
PhenoperidineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Phenoperidine.Experimental
PhenoxyethanolThe risk or severity of adverse effects can be increased when Phenoxyethanol is combined with Eltanolone.Approved
PhenytoinThe risk or severity of adverse effects can be increased when Phenytoin is combined with Eltanolone.Approved, Vet Approved
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Eltanolone.Approved
PipamperoneThe risk or severity of adverse effects can be increased when Pipamperone is combined with Eltanolone.Approved, Investigational
PipotiazineThe risk or severity of adverse effects can be increased when Pipotiazine is combined with Eltanolone.Approved, Investigational
PiritramideThe risk or severity of adverse effects can be increased when Eltanolone is combined with Piritramide.Approved, Investigational
PizotifenThe risk or severity of adverse effects can be increased when Pizotifen is combined with Eltanolone.Approved
PomalidomideThe risk or severity of adverse effects can be increased when Pomalidomide is combined with Eltanolone.Approved
PramipexoleEltanolone may increase the sedative activities of Pramipexole.Approved, Investigational
PramocaineThe risk or severity of adverse effects can be increased when Pramocaine is combined with Eltanolone.Approved
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Eltanolone.Approved, Illicit
PregabalinThe therapeutic efficacy of Eltanolone can be increased when used in combination with Pregabalin.Approved, Illicit, Investigational
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Eltanolone.Approved
PrimidoneThe risk or severity of adverse effects can be increased when Primidone is combined with Eltanolone.Approved, Vet Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Eltanolone.Approved, Investigational, Vet Approved
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Eltanolone.Approved, Vet Approved
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Eltanolone.Approved, Vet Approved
PromethazineThe risk or severity of adverse effects can be increased when Promethazine is combined with Eltanolone.Approved, Investigational
PropanididThe risk or severity of adverse effects can be increased when Eltanolone is combined with Propanidid.Experimental
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Eltanolone.Approved, Vet Approved
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Eltanolone.Approved, Investigational, Vet Approved
PropoxycaineThe risk or severity of adverse effects can be increased when Propoxycaine is combined with Eltanolone.Approved
ProtriptylineThe risk or severity of adverse effects can be increased when Protriptyline is combined with Eltanolone.Approved
ProxibarbalThe risk or severity of adverse effects can be increased when Eltanolone is combined with Proxibarbal.Experimental
PSD502The risk or severity of adverse effects can be increased when PSD502 is combined with Eltanolone.Investigational
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Eltanolone.Approved, Illicit
QuetiapineThe risk or severity of adverse effects can be increased when Quetiapine is combined with Eltanolone.Approved
QuinisocaineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Quinisocaine.Experimental
RacloprideThe risk or severity of adverse effects can be increased when Eltanolone is combined with Raclopride.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Ramelteon is combined with Eltanolone.Approved, Investigational
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Eltanolone.Approved
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Eltanolone.Approved, Withdrawn
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Eltanolone.Approved, Investigational
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Eltanolone.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Eltanolone is combined with Ritanserin.Investigational
RomifidineThe risk or severity of adverse effects can be increased when Romifidine is combined with Eltanolone.Vet Approved
RopiniroleEltanolone may increase the sedative activities of Ropinirole.Approved, Investigational
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Eltanolone.Approved
RotigotineEltanolone may increase the sedative activities of Rotigotine.Approved
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Eltanolone.Approved
ScopolamineThe risk or severity of adverse effects can be increased when Scopolamine is combined with Eltanolone.Approved, Investigational
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with Eltanolone.Approved, Vet Approved
SepranoloneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Sepranolone.Investigational
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Eltanolone.Approved, Investigational, Withdrawn
SertralineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Sertraline.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Eltanolone.Approved, Vet Approved
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved
StiripentolThe risk or severity of adverse effects can be increased when Stiripentol is combined with Eltanolone.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Eltanolone.Approved, Investigational
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Eltanolone.Approved, Investigational
SultoprideThe risk or severity of adverse effects can be increased when Eltanolone is combined with Sultopride.Experimental
SuvorexantEltanolone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved, Investigational
TandospironeThe risk or severity of adverse effects can be increased when Eltanolone is combined with Tandospirone.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Eltanolone.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Tasimelteon is combined with Eltanolone.Approved, Investigational
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Eltanolone.Approved, Investigational
TetrabenazineThe risk or severity of adverse effects can be increased when Tetrabenazine is combined with Eltanolone.Approved, Investigational
TetracaineThe risk or severity of adverse effects can be increased when Tetracaine is combined with Eltanolone.Approved, Vet Approved
TetrahydropalmatineThe risk or severity of adverse effects can be increased when Tetrahydropalmatine is combined with Eltanolone.Investigational
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Eltanolone.Investigational
ThalidomideEltanolone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with Eltanolone.Approved, Vet Approved
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Eltanolone.Approved, Vet Approved
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Eltanolone.Approved, Withdrawn
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Eltanolone.Approved
TiagabineThe risk or severity of adverse effects can be increased when Tiagabine is combined with Eltanolone.Approved, Investigational
TiaprideThe risk or severity of adverse effects can be increased when Eltanolone is combined with Tiapride.Approved, Investigational
TiletamineThe risk or severity of adverse effects can be increased when Tiletamine is combined with Eltanolone.Vet Approved
TilidineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Tilidine.Experimental
TizanidineThe risk or severity of adverse effects can be increased when Tizanidine is combined with Eltanolone.Approved, Investigational
TolcaponeThe risk or severity of adverse effects can be increased when Tolcapone is combined with Eltanolone.Approved, Withdrawn
TopiramateThe risk or severity of adverse effects can be increased when Topiramate is combined with Eltanolone.Approved
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Eltanolone.Approved, Investigational
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Eltanolone.Approved, Investigational
TrazodoneThe risk or severity of adverse effects can be increased when Trazodone is combined with Eltanolone.Approved, Investigational
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Eltanolone.Approved, Investigational
Tricaine methanesulfonateThe risk or severity of adverse effects can be increased when Tricaine methanesulfonate is combined with Eltanolone.Vet Approved
TrichloroethyleneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Trichloroethylene.Approved
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Eltanolone.Approved, Investigational
TrifluperidolThe risk or severity of adverse effects can be increased when Eltanolone is combined with Trifluperidol.Experimental
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Eltanolone.Approved, Vet Approved
TrimipramineThe risk or severity of adverse effects can be increased when Trimipramine is combined with Eltanolone.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Triprolidine is combined with Eltanolone.Approved
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Eltanolone.Approved, Investigational
VenlafaxineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Venlafaxine.Approved
VeraliprideThe risk or severity of adverse effects can be increased when Eltanolone is combined with Veralipride.Experimental
VigabatrinThe risk or severity of adverse effects can be increased when Vigabatrin is combined with Eltanolone.Approved
Vinyl etherThe risk or severity of adverse effects can be increased when Eltanolone is combined with Vinyl ether.Experimental
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Eltanolone.Approved, Investigational
XenonThe risk or severity of adverse effects can be increased when Eltanolone is combined with Xenon.Experimental
XylazineThe risk or severity of adverse effects can be increased when Xylazine is combined with Eltanolone.Vet Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Eltanolone.Approved, Illicit, Investigational
ZiconotideThe risk or severity of adverse effects can be increased when Ziconotide is combined with Eltanolone.Approved
ZimelidineThe risk or severity of adverse effects can be increased when Eltanolone is combined with Zimelidine.Withdrawn
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Eltanolone.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Zolazepam is combined with Eltanolone.Vet Approved
ZolpidemEltanolone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.Approved
ZonisamideThe risk or severity of adverse effects can be increased when Zonisamide is combined with Eltanolone.Approved, Investigational
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Eltanolone.Approved
ZotepineThe risk or severity of adverse effects can be increased when Zotepine is combined with Eltanolone.Approved, Investigational, Withdrawn
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with Eltanolone.Approved, Investigational
Food Interactions
Not Available

References

General References
Not Available
External Links
Human Metabolome Database
HMDB0062782
PubChem Compound
31402
PubChem Substance
347828573
ChemSpider
29132
ChEBI
1712
ChEMBL
CHEMBL210952
HET
P9N
Wikipedia
Pregnanolone
PDB Entries
5o8f

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00136 mg/mLALOGPS
logP4.28ALOGPS
logP3.99ChemAxon
logS-5.4ALOGPS
pKa (Strongest Acidic)18.3ChemAxon
pKa (Strongest Basic)-1.4ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area37.3 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity92.91 m3·mol-1ChemAxon
Polarizability38.36 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as gluco/mineralocorticoids, progestogins and derivatives. These are steroids with a structure based on a hydroxylated prostane moiety.
Kingdom
Organic compounds
Super Class
Lipids and lipid-like molecules
Class
Steroids and steroid derivatives
Sub Class
Pregnane steroids
Direct Parent
Gluco/mineralocorticoids, progestogins and derivatives
Alternative Parents
20-oxosteroids / 3-alpha-hydroxysteroids / Secondary alcohols / Ketones / Cyclic alcohols and derivatives / Organic oxides / Hydrocarbon derivatives
Substituents
Progestogin-skeleton / 20-oxosteroid / 3-hydroxysteroid / Hydroxysteroid / 3-alpha-hydroxysteroid / Oxosteroid / Cyclic alcohol / Ketone / Secondary alcohol / Organooxygen compound
Molecular Framework
Aliphatic homopolycyclic compounds
External Descriptors
3alpha-hydroxy steroid, 3-hydroxy-5beta-pregnan-20-one (CHEBI:1712) / C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives (LMST02030175)

Drug created on October 20, 2016 15:53 / Updated on May 02, 2018 00:18