Central Nervous System Agents

A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)
DrugDrug NameDrug Indication
DB00042Botulinum Toxin Type BFor the treatment of patients with cervical dystonia to reduce the severity of abnormal head position and neck pain associated with cervical dystonia.
DB00122CholineFor nutritional supplementation, also for treating dietary shortage or imbalance
DB00150L-TryptophanTryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight.
DB00176FluvoxamineIndicated predominantly for the management of depression and for Obsessive Compulsive Disorder (OCD) [FDA Label]. Has also been used in the management of bulimia nervosa [A250].
DB00179MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
DB00181BaclofenBaclofen is administered for the relief of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and associated pain and clonus, in addition to muscular rigidity [FDA label]. Patients receiving this drug should have reversible spasticity for baclofen to promote the restoration of residual function. This drug is not indicated in the treatment of skeletal muscle spasm caused by rheumatic disorders. The efficacy of baclofen in stroke, cerebral palsy, and Parkinson's disease has not been determined and, therefore, baclofen is not recommended for these conditions [FDA label].
DB00182AmphetamineAmphetamine is indicated for the treatment of attention-deficit/hyperactivity disorders (ADHD) as well as for the treatment of central nervous system disorders such as narcolepsy.[A18540] ADHD is a complex disorder associated with the substantial heterogeneity in etiology, clinical presentation, and treatment outcome. ADHD comes from a complex interplay between interdependent genetic and non-genetic factors which cause complex mental disorders in children and teenagers.[A174271] On the other hand, narcolepsy is a chronic sleep disorder typically resenting during adolescence and characterized by excessive daytime sleepiness.[A174274] Amphetamine is also being used nowadays off-label for the treatment of obesity, depression and chronic pain.[A174268, A174283]
DB00186LorazepamLorazepam is FDA-approved for the short-term relief of anxiety symptoms related to anxiety disorders and anxiety associated with depressive symptoms such as anxiety-associated insomnia. It is as well used as an anesthesia premedication in adults to relieve anxiety or to produce sedation/amnesia and for the treatment of status epilepticus.[T385] Some off-label indications of lorazepam include rapid tranquilization of an agitated patient, alcohol withdrawal delirium, alcohol withdrawal syndrome, muscle spasms, insomnia, panic disorder, delirium, chemotherapy-associated anticipatory nausea and vomiting, and psychogenic catatonia.[T385]
DB00189EthchlorvynolUsed for short-term hypnotic therapy in the management of insomnia for periods of up to one week in duration; however, this medication generally has been replaced by other sedative-hypnotic agents.
DB00190CarbidopaCarbidopa is indicated with [levodopa] for the treatment of symptoms of idiopathic Parkinson disease, postencephalitic parkinsonism and symptomatic parkinsonism followed by carbon monoxide or manganese intoxication.[FDA label] The combination therapy is administered for the reduction of [levodopa]-driven nausea and vomiting.[FDA label] The product of carbidopa should be used in patients where the combination therapy of carbidopa/[levodopa] provide less than the adequate daily dosage.[FDA label] As well carbidopa can be used in patients where the dosages of carbidopa and [levodopa] require individual titration.[FDA label]
DB00191PhenterminePhentermine is indicated, alone or in combination with topiramate, as a short-term adjunct, not pass a few weeks, in a regimen of weight reduction based on exercise, behavioral modifications and caloric restriction in the management of exogenous obesity for patients with an initial body mass index (BMI) greater than 30 kg/m2 or greater than 27 kg/m2 in presence of other risk factors such as controller hypertension, diabetes or hyperlipidemia.[FDA label] Exogenous obesity is considered when the overweight is caused by consuming more food than the person activity level warrants. This condition commonly causes an increase in fat storage. It is an epidemic condition in the United States where over two-thirds of adults are overweight or obese and one in three Americans is obese. In the world, the incidence of obesity has nearly doubled.[A174391]
DB00193TramadolTramadol is approved for the management of moderate to severe pain in adults.[FDA label] As an off-label indication, tramadol has been investigated to be used for the treatment of premature ejaculation.[A173986]
DB00201CaffeineFor management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
DB00206ReserpineFoe the treatment of hypertension
DB00210AdapaleneFor the topical treatment of comedo, papular and pustular acne (acne vulgaris) of the face, chest or back.
DB00215CitalopramFor the treatment of depression, as indicated by the FDA label [FDA label]. Off-label indications include but are not limited to: treatment of sexual dysfunction, post-stroke behavioural changes, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label], [A321], [A322], [A323], [A324], [A174406], [A174409], [A174412].
DB00228EnfluraneUsed for the induction and maintenance of general anaesthesia during surgery and cesarean section and also used for analgesia during vaginal delivery.
DB00230PregabalinPregabalin is used for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, and as adjunctive therapy for adult patients with partial onset seizures [FDA label].
DB00231TemazepamTemazepam is specifically indicated only for the short-term management of insomnia [FDA Label], [L5539]. Furthermore, such management is generally predominantly associated with the symptomatic relief of transient and short-term insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings and/or early morning awakenings [F3718]. In particular, the official prescribing information for temazepam typically specifies that the instructions issued for dispensed prescriptions of the medication should indicate specifically that patients are only expected to use the therapy for short periods of time - usually 7-10 days in general [FDA Label, F3718]. Subsequently, treatment with temazepam should usually not exceed 7 to 10 consecutive days and nor should it be prescribed in quantities exceeding a one-month supply [F3718]. Some regional prescribing information also notes that temazepam may be used for premedication prior to minor surgery or other related procedures [L5539].
DB00234ReboxetineFor the treatment of clinical depression.
DB00237ButabarbitalFor short-term treatment of insomnia and anxiety disorders
DB00245BenzatropineBenztropine is indicated to be used as an adjunct in the therapy of all forms of parkinsonism. It can also be used for the control of extrapyramidal disorders due to neuroleptic drugs.[T203] The extrapyramidal symptoms are defined as drug-induced disorders that include symptoms of dystonia, akathisia, parkinsonism, bradykinesia, tremors, and dyskinesia.[A175120] Parkinsonism is a general term that refers to the group of neurological disorders that produce symptoms similar to Parkinson's disease such as tremors, slow movement, and stiffness. The parkinsonism includes a large number of disorders and some of them have not been clearly defined.[L5509]
DB00246ZiprasidoneIn it's oral form, ziprasidone is approved for the treatment of Schizophrenia and Bipolar I disorder while the injectable formulation is approved for treatment of acute agitation in schizophrenia.
DB00248CabergolineFor the treatment of hyperprolactinemic disorders, either idiopathic or due to prolactinoma (prolactin-secreting adenomas). May also be used to manage symptoms of Parkinsonian Syndrome as monotherapy during initial symptomatic management or as an adjunct to levodopa therapy during advanced stages of disease.
DB00252PhenytoinFor the control of generalized tonic-clonic (grand mal) and complex partial (psychomotor, temporal lobe) seizures and prevention and treatment of seizures occurring during or following neurosurgery.
DB00268RopiniroleFor the treatment of the signs and symptoms of Parkinson's disease and for the treatment of primary moderate-severe restless legs syndrome [FDA label].
DB00273TopiramateTopiramate is indicated for the following conditions: - Monotherapy for partial onset or primary generalized tonic-clonic seizures in patients over 2 years of age. - Adjunctive therapy for partial onset seizures or primary generalized tonic-clonic seizures for adult and pediatric patients. - Adjunctive therapy for seizures associated with Lennox-Gastaut syndrome in patients over 2 years of age. - Prophylaxis of migraine headache in adults.[FDA label] A seizure is an abnormal, unregulated electrical discharge occurring in the brain's cortical gray matter. This electrical response produces a transient interruption in the normal brain function which in order produces altered awareness, abnormal sensations, focal involuntary movements or convulsions. The type of seizure can be classified according to the type of onset followed by a type of seizure.[L5548] A migraine headache is a [ulsating or throbbing pain that can be presented in one of both sides of the head and it can be worsened by external stimuli such as physical activity, light, sounds, and odors.[L5551] Topiramate has been commonly investigated and used off-label for weight reduction in patients with obesity or diabetes.[A175240]
DB00281LidocaineLidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks [F4349, L5930].
DB00285VenlafaxineVenlafaxine is indicated in the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), and panic disorder with or without agoraphobia. Venlafaxine is also used off-label for prophylaxis of migraine headaches [A177229], for reduction of vasomotor symptoms associated with menopause [A177238], and for management of neuropathic pain (although there is only minimal evidence of efficacy for this condition) [A177232]. It is also considered a second-line option for management of obsessive-compulsive disorder (OCD) [A177226, A177235].
DB00292EtomidateUsed in the induction of general anesthesia.
DB00295MorphineMorphine is used for the management of chronic moderate-to-severe pain.[A176050] Opioids, including morphine, can manage pain effectively when used for a short amount of time. The use of opioids for longer periods needs to be monitored as they can develop a physical dependence, addiction disorder and drug abuse.[L5728]
DB00296RopivacaineUsed in obstetric anesthesia and regional anesthesia for surgery.
DB00297BupivacaineFor the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures.
DB00298DapiprazoleUsed in the treatment of iatrogenically induced mydriasis produced by adrenergic (phenylephrine) or parasympatholytic (tropicamide) agents used in certain eye examinations.
DB00312PentobarbitalFor the short-term treatment of insomnia.
DB00313Valproic AcidFor treatment and management of seizure disorders, mania, and prophylactic treatment of migraine headache. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome.
DB00316AcetaminophenIn general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever [F4124]. It is available over the counter in various forms, the most common being oral forms. Acetaminophen _injection_ is indicated for [FDA label]: • Management of mild to moderate pain • Management of moderate to severe pain with adjunctive opioid analgesics • Reduction of fever Because of its low risk of causing allergic reactions, this drug can be administered in patients who are intolerant to salicylates and those with allergic tendencies, including bronchial asthmatics [F4124]. Specific dosing guidelines should be followed when administering acetaminophen to children [L5780].
DB00318CodeineCodeine sulfate is a form of this drug that is commonly used. It is available in tablet form [FDA label] and indicated for the relief of mild to moderately severe pain, where the use of an opioid analgesic is appropriate [FDA label]. The solution form is used by itself or combined in a syrup with other drugs and is used as a cough suppressant in adults aged 18 and above [L5521], [L5524].
DB00320DihydroergotamineFor the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes.
DB00321AmitriptylineThis drug in indicated for the following conditions [FDA label]: Major depressive disorder in adults Management of neuropathic pain in adults Prophylactic treatment of chronic tension-type headache (CTTH) in adults Prophylactic treatment of migraine in adults Treatment of nocturnal enuresis in children aged 6 years and above when organic pathology, including spina bifida and related disorders, have been excluded and no response has been achieved to all other non-drug and drug treatments, including antispasmodics and vasopressin-related products. This product should only be prescribed by a healthcare professional with expertise in the management of persistent enuresis [FDA label] Off-label uses: irritable bowel syndrome, sleep disorders, diabetic neuropathy, agitation, fibromyalgia, and insomnia
DB00323TolcaponeUsed as an adjunct to levodopa/carbidopa therapy for the symptomatic treatment of Parkinson's Disease. This drug is generally reserved for patients with parkinsonian syndrome receiving levodopa/carbidopa who are experiencing symptom fluctuations and are not responding adequately to or are not candidates for other adjunctive therapies.
DB00327HydromorphoneHydromorphone is indicated for the management of moderate to severe acute pain and severe chronic pain. Due to its addictive potential and overdose risk, hydromorphone is only prescribed when other first-line treatments have failed.[A176468] The WHO has proposed a three-step ladder for the management of pain in which it is suggested to start with a non-opioid medication followed by addition of weak opioids to the non-opioid treatment for moderate pain and finishing in the use of strong opioids such as hydromorphone along with the existing regimen for cases of severe pain.[A176471] Off-label, hydromorphone can be administered for the suppression of refractory cough.[A176468]
DB00328IndometacinFor moderate to severe rheumatoid arthritis including acute flares of chronic disease, ankylosing spondylitis, osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
DB00333MethadoneFor the treatment of dry cough, drug withdrawal syndrome, opioid type drug dependence, and pain.
DB00334OlanzapineOlanzapine was initially used orally and intramuscularly for the chronic treatment of schizophrenia in patients over 13 years old and other psychiatric disorders such as bipolar I disorder including mixed or manic episodes.[A177014] Olanzapine is also indicated, in combination with lithium or valproate for the short-term treatment of acute manic or mixed episodes associated with bipolar I disorder in adults.[FDA label] As well, olanzapine is indicated, in combination with fluoxetine for the treatment of episodes of depression associated with bipolar disorder type 1 and treatment-resistant depression in patients over 10 years old.[A177014] Olanzapine is also approved for the management of psychomotor agitation associated with schizophrenia and bipolar I mania.[FDA label] Schizophrenia is a complex biochemical brain disorder that affects the person's ability to differentiate reality. It is usually observed as the presence of delusions, hallucinations, social withdrawal and disturbed thinking.[L5936] Bipolar disorder is a mental health condition defined by periods of extreme mood disturbances. It is categorized in different types from which type 1 is known to involve episodes of severe mania and often depression while type 2 presents less severe forms of mania.[L5939]
DB00337PimecrolimusFor treatment of mild to moderate atopic dermatitis.
DB00344ProtriptylineFor the treatment of depression.
DB00347TrimethadioneUsed in the control of absence (petit mal) seizures that are refractory to treatment with other medications.
DB00349ClobazamFor treatment and management of epilepsy and seizures associated with Lennox-Gastaut syndrome, a difficult-to-treat form of childhood epilepsy.
DB00351Megestrol acetateFor the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used for the palliative management of recurrent, inoperable, or metastatic breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.
DB00356ChlorzoxazoneFor the relief of discomfort associated with acute painful musculoskeletal conditions.
DB00363ClozapineFor use in patients with treatment-resistant schizophrenia.
DB00366DoxylamineUsed alone as a short-term sleep aid, in combination with other drugs as a night-time cold and allergy relief drug. Also used in combination with Vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.
DB00370MirtazapineFor the treatment of major depressive disorder.
DB00371MeprobamateFor the management of anxiety disorders or for the short-term relief of the symptoms of anxiety.
DB00372ThiethylperazineFor the treatment or relief of nausea and vomiting.
DB00376TrihexyphenidylIndicated for the treatment of parkinson's disease and extrapyramidal reactions caused by drugs.
DB00382TacrineFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
DB00387ProcyclidineFor the treatment of all forms of Parkinson's Disease, as well as control of extrapyramidal reactions induced by antipsychotic agents.
DB00391SulpirideSulpiride is indicated for the treatment of schizophrenia.
DB00395CarisoprodolCarisoprodol is indicated for the relief of discomfort related to acute, painful musculoskeletal conditions [FDA label]. **Important limitations of use** [FDA label]: • Should only be used for acute treatment periods up to two or three weeks • Adequate evidence of effectiveness for more prolonged use has not been established • Not recommended in pediatric patients less than 16 years of age
DB00397PhenylpropanolamineFor the treatment of nasal congestion, control of urinary incontinence, priapism and obesity.
DB00402EszopicloneFor the treatment of insomnia
DB00404AlprazolamFor the management of anxiety disorder or the short-term relief of symptoms of anxiety and for the treatment of panic disorder, with or without agoraphobia.
DB00408LoxapineFor the management of the manifestations of psychotic disorders such as schizophrenia
DB00409RemoxiprideRemoxipride is an atypical antipsychotic once used for the treatment of schizophrenia.
DB00411CarbamoylcholinePrimarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
DB00413PramipexoleThis drug is indicated for the symptomatic treatment of Parkinson’s disease [FDA label]. This drug can be administered as monotherapy or in conjunction with levodopa. It is also indicated for symptomatic treatment of moderate to severe primary Restless Legs Syndrome (RLS) [FDA label].
DB00418SecobarbitalFor the Short-term treatment of intractable insomnia for patients habituated to barbiturates
DB00420PromazineUsed as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
DB00422MethylphenidateMethylphenidate is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years of age and older and for the treatment of narcolepsy.
DB00423MethocarbamolFor use as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions.
DB00424HyoscyamineFor treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.
DB00425ZolpidemThis drug is indicated for the short-term treatment of insomnia in adults characterized by difficulties with sleep initiation [FDA label].
DB00433ProchlorperazineFor the symptomatic management of psychotic disorders, short term management of nonpsychotic anxiety in patients with generalized anxiety disorder, and for the control of severe nausea and vomiting of various causes.
DB00450DroperidolDroperidol is ssed to produce tranquilization and to reduce the incidence of nausea and vomiting in surgical and diagnostic procedures.
DB00454MeperidineUsed to control moderate to severe pain.
DB00458ImipramineFor the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older [FDA Label]. May also be used off-label to manage panic disorders with or without agoraphobia, as a second line agent for ADHD in children and adolescents, to manage bulimia nervosa, for short-term management of acute depressive episodes in bipolar disorder and schizophrenia, for the treatment of acute stress disorder and posttraumatic stress disorder, and for symptomatic treatment of postherpetic neuralgia and painful diabetic neuropathy [L1349,L1348,A31900,L1351,L1352,L1353,A31904].
DB00461NabumetoneFor acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00466PicrotoxinUsed internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
DB00468QuinineFor the treatment of malaria and leg cramps
DB00469TenoxicamFor the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain.
DB00470DronabinolFor the treatment of anorexia associated with weight loss in patients with AIDS, and nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments
DB00472FluoxetineLabeled indication include: major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism, mild dementia-associated agitation in nonpsychotic patients, post-traumatic stress disorder (PTSD), social anxiety disorder, chronic neuropathic pain, fibromyalgia, and Raynaud's phenomenon.
DB00474MethohexitalMethohexital is indicated for use as an intravenous anaesthetic. It has also been commonly used to induce deep sedation.
DB00475ChlordiazepoxideFor the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.
DB00476DuloxetineFor the acute and maintenance treatment of major depressive disorder (MDD), as well as acute management of generalized anxiety disorder. Also used for the management of neuropathic pain associated with diabetic peripheral neuropathy, and fibromyalgia. Has been used in the management of moderate to severe stress urinary incontinence (SUI) in women.
DB00477ChlorpromazineFor the treatment of schizophrenia; to control nausea and vomiting; for relief of restlessness and apprehension before surgery; for acute intermittent porphyria; as an adjunct in the treatment of tetanus; to control the manifestations of the manic type of manic-depressive illness; for relief of intractable hiccups; for the treatment of severe behavioral problems in children (1 to 12 years of age) marked by combativeness and/or explosive hyperexcitable behavior (out of proportion to immediate provocations), and in the short-term treatment of hyperactive children who show excessive motor activity with accompanying conduct disorders consisting of some or all of the following symptoms: impulsivity, difficulty sustaining attention, aggressivity, mood lability, and poor frustration tolerance.
DB00482CelecoxibFor the relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis [FDA label].
DB00486NabiloneNabilone is indicated for the treatment of the nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments. This restriction is required because a substantial proportion of any group of patients treated with Nabilone can be expected to experience disturbing psychotomimetic reactions not observed with other antiemetic agents.
DB00490BuspironeFor the management of anxiety disorders or the short-term relief of the symptoms of anxiety, and also as an augmention of SSRI-treatment against depression.
DB00494EntacaponeUsed as an adjunct to levodopa / carbidopa in the symptomatic treatment of patients with idiopathic Parkinson's Disease who experience the signs and symptoms of end-of-dose "wearing-off".
DB00497OxycodoneFor the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
DB00500TolmetinFor the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis, including the treatment of acute flares long-term management. Also for treatment of juvenile rheumatoid arthritis.
DB00502HaloperidolFor the treatment of schizophrenia [L2016] For the treatment of acute psychosis in acutely agitated schizophrenic patients with moderately severe to very severe symptoms [L2016] For the treatment of severe behavioral or psychological symptoms of dementia [L2016] For the treatment of delirium in the pediatric intensive care unit [L2016] For the treatment of agitation or delirium [L2016] For agitation† or delirium in adult patients with no underlying psychiatric illness [L2016] For use as a second-line agent for rescue treatment of chemotherapy-induced nausea/vomiting [L2016] For the treatment of irritability associated with autistic disorder [L2016] For the treatment of tics and vocal utterances associated with Tourette's syndrome [L2016] For the treatment of severe behavioral problems associated with oppositional defiant disorder or other disruptive behavioral disorders, or for the treatment of attention-deficit hyperactivity disorder (ADHD) in pediatric patients who show excessive motor activity with accompanying conduct disorders [L2016]
DB00504LevallorphanFor the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.
DB00508TriflupromazineUsed mainly in the management of psychoses. Also used to control nausea and vomiting.
DB00514DextromethorphanFor treatment and relief of dry cough.
DB00527CinchocaineFor production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
DB00532MephenytoinFor the treatment of refractory partial epilepsy.
DB00533RofecoxibFor the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras.
DB00540NortriptylinePrimarily indicated for the relief of symptoms of depression.
DB00543AmoxapineFor the relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depressions. May also be used to treat depression accompanied by anxiety or agitation.
DB00546AdinazolamFor the treatment of anxiety and status epilepticus.
DB00554PiroxicamFor treatment of osteoarthritis and rheumatoid arthritis.
DB00555LamotrigineIndicated as adjunctive therapy for the following seizure types in patients ≥2 years of age: partial seizures/primary generalized tonic-clonic seizures/generalized seizures of Lennox-Gastaut syndrome [FDA Label]. Indicated for conversion to monotherapy in adults (≥16 years of age) with partial seizures who are receiving treatment with carbamazepine, phenytoin, phenobarbital, primidone, or valproate as the single antiepileptic drug (AED)[FDA Label]. Indicated for the maintenance treatment of Bipolar I Disorder to delay the time to occurrence of mood episodes (depression, mania, hypomania, mixed episodes) in adults (≥18 years of age) treated for acute mood episodes with standard therapy [FDA Label].
DB00561DoxapramFor use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.
DB00564CarbamazepineFor the treatment of epilepsy and pain associated with true trigeminal neuralgia.
DB00572AtropineFor the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
DB00573FenoprofenFor relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.
DB00575ClonidineMay be used as an adjunct in the treatment of hypertension, as an epidural infusion as an adjunct treatment in the management of severe cancer pain that is not relieved by opiate analgesics alone, for differential diagnosis of pheochromocytoma in hypertensive patients, prophylaxis of vascular migraine headaches, treatment of severe dysmenorrhea, management of vasomotor symptoms associated with menopause, rapid detoxification in the management of opiate withdrawal, treatment of alcohol withdrawal used in conjunction with benzodiazepines, management of nicotine dependence, topical use to reduce intraocular pressure in the treatment of open-angle and secondary glaucoma and hemorrhagic glaucoma associated with hypertension, and in the treatment of attention-deficit hyperactivity disorder (ADHD).
DB00579MazindolUsed in short-term (a few weeks) treatment of exogenous obesity in conjunction with a regimen of weight reduction based on caloric restriction, exercise, and behavior modification in patients with a body mass index of 30 kg of body weight per height in meters squared (kg/m2) or in patients with a body mass index of 27 kg/m2 in the presence of risk factors such as hypertension, diabetes, or hyperlipidemia.
DB00580ValdecoxibFor the treatment of osteoarthritis and dysmenorrhoea
DB00586DiclofenacFor the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00589LisurideFor the management of Parkinson's Disease
DB00593EthosuximideFor the treatment of petit mal epilepsy.
DB00599ThiopentalFor use as the sole anesthetic agent for brief (15 minute) procedures, for induction of anesthesia prior to administration of other anesthetic agents, to supplement regional anesthesia, to provide hypnosis during balanced anesthesia with other agents for analgesia or muscle relaxation, for the control of convulsive states during or following inhalation anesthesia or local anesthesia, in neurosurgical patients with increased intracranial pressure, and for narcoanalysis and narcosynthesis in psychiatric disorders.
DB00605SulindacFor acute or long-term use in the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute painful shoulder (acute subacromial bursitis/supraspinatus tendinitis), and acute gouty arthritis.
DB00608ChloroquineFor the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis
DB00611ButorphanolFor the relief of moderate to severe pain.
DB00623FluphenazineFor management of manifestations of psychotic disorders.
DB00628Clorazepic acidFor the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal.
DB00633DexmedetomidineFor sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
DB00640AdenosineUsed as an initial treatment for the termination of paroxysmal supraventricular tachycardia (PVST), including that associated with accessory bypass tracts, and is a drug of choice for terminating stable, narrow-complex supraventricular tachycardias (SVT). Also used as an adjunct to thallous chloride TI 201 myocardial perfusion scintigraphy (thallium stress test) in patients who are unable to exercise adequately, as well as an adjunct to vagal maneuvers and clinical assessment to establish a specific diagnosis of undefined, stable, narrow-complex SVT.
DB00645DyclonineUsed to provide topical anesthesia of accessible mucous membranes prior to examination, endoscopy or instrumentation, or other procedures involving the esophagus, larynx, mouth, pharynx or throat, respiratory tract or trachea, urinary tract, or vagina. Also used to suppress the gag reflex and/or other laryngeal and esophageal reflexes to facilitate dental examination or procedures (including oral surgery), endoscopy, or intubation. Also used for relief of canker sores, cold sores or fever blister.
DB00647DextropropoxypheneFor the relief of mild to moderate pain
DB00652PentazocineFor the relief of moderate to severe pain.
DB00653Magnesium sulfateUsed for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
DB00656TrazodoneFor the treatment of depression.
DB00659AcamprosateFor the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation
DB00662TrimethobenzamideFor the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
DB00673AprepitantFor the prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy, including high-dose cisplatin (in combination with other antiemetic agents).
DB00674GalantamineFor the treatment of mild to moderate dementia of the Alzheimer's type. Has also been investigated in patients with mild cognitive impairment who did not meet the diagnostic criteria for Alzheimer's disease.
DB00679ThioridazineFor the treatment of schizophrenia and generalized anxiety disorder.
DB00683MidazolamThe midazolam intravenous injection is indicated for preoperative sedation/anxiolysis/anesthesia induction/amnesia [F2434], and the intramuscular injection is indicated for the treatment of status epilepticus in adults [FDA label]. Midazolam is also an agent for conscious sedation/anxiolysis/amnesia prior to or during diagnostic, therapeutic, or endoscopic procedures. It is important to note that various routes may be applicable to different indications. Refer to the "indications" section of this drug entry for more detailed information.
DB00690FlurazepamFor short-term and intermittent use in patients with recurring insomnia and poor sleeping habits
DB00696ErgotamineFor use as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants, or so called "histaminic cephalalgia".
DB00697TizanidineTizanidine is indicated for the relief of muscle spasticity, which can interfere with daily activities. The general recommendation is to reserve tizanidine use for periods of time when there is a particular need for relief, as it has a short duration of action [FDA label, F4471].
DB00699NicergolineFor the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration.
DB00704NaltrexoneUsed as an adjunct to a medically supervised behaviour modification program in the maintenance of opiate cessation in individuals who were formerly physically dependent on opiates and who have successfully undergone detoxification. Also used for the management of alcohol dependence in conjunction with a behavioural modification program.
DB00708SufentanilThe indications for this drug are as follows: 1. As an analgesic adjunct in the maintenance of balanced general anesthesia in patients who are intubated and ventilated. 2. As a primary anesthetic agent for the induction and maintenance of anesthesia with 100% oxygen in patients undergoing major surgical procedures, in patients who are intubated and ventilated, such as cardiovascular surgery or neurosurgical procedures in the sitting position, to provide favorable myocardial and cerebral oxygen balance or when extended postoperative ventilation is anticipated. 3. For epidural administration as an analgesic combined with low dose (usually 12.5 mg per administration) bupivacaine usually during labor and vaginal delivery 4. The sublingual form is indicated for the management of acute pain in adults that is severe to warrant the use of an opioid analgesic in certified medically supervised healthcare settings, including hospitals, surgical centers, and emergency departments. [FDA label]
DB00712FlurbiprofenFlurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis.
DB00714ApomorphineFor the acute, intermittent treatment of hypomobility, off episodes (end-of-dose wearing off and unpredictable on/off episodes) associated with advanced Parkinson's disease.
DB00715ParoxetineLabeled indications include: major depressive disorder (MDD), panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Unlabeled indications include: eating disorders, impulse control disorders, vasomotor symptoms of menopause, obsessive-compulsive disorder (OCD) in children, and mild dementia-associated agitation in nonpsychotic individuals. Brisdelle, which consists of paroxetine mesylate is indicated for the treatment of moderate to severe vasomotor symptoms (like hot flashes) associated with menopause.
DB00721ProcaineUsed as a local anesthetic primarily in oral surgery
DB00726TrimipramineFor the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance
DB00734RisperidoneRisperidone belongs to the class of medications known as ​second generation atypical antipsychotics [A1114, A1115, L1213]. It is widely used in the treatment of schizophrenia and mood disorders, including bipolar disorder and depression with pyschosis [A1115, A1116, L1212, L1213].
DB00737MeclizineFor the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness.
DB00740RiluzoleFor the treatment of amyotrophic lateral sclerosis (ALS, Lou Gehrig's Disease)
DB00744ZileutonFor the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older.
DB00745ModafinilTo improve wakefulness in patients with excessive daytime sleepiness (EDS) associated with narcolepsy.
DB00747ScopolamineFor the treatment of excessive salivation, colicky abdominal pain, bradycardia, sialorrhoea, diverticulitis, irritable bowel syndrome and motion sickness.
DB00749EtodolacFor acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain.
DB00750PrilocaineUsed as a local anaesthetic and is often used in dentistry.
DB00752TranylcypromineFor the treatment of major depressive episode without melancholia.
DB00753IsofluraneFor induction and maintenance of general anesthesia.
DB00754EthotoinFor the control of tonic-clonic (grand mal) and complex partial (psychomotor) seizures.
DB00757DolasetronFor the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including initial and repeat courses of chemotherapy. Also used for the prevention of postoperative nausea and vomiting. This drug can be used intravenously for the treatment of postoperative nausea and vomiting.
DB00768OlopatadineFor the treatment of ocular itching associated with allergic conjunctivitis.
DB00776OxcarbazepineFor use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy and as adjunctive therapy in the treatment of partial seizures in children ages 4-16 with epilepsy.
DB00780PhenelzinePhenelzine is indicated for the treatment of nonendogenous, neurotic or atypical depression for patients that do not tolerate other forms of therapy.[L1356] Atypical depression has a high prevalence rate, starts in early life, tends to last longer, is more likely to occur in people with bipolar disorder, has a high comorbidity with anxiety disorder and carries more risk of suicidal behavior. It is important to specify the atypical feature to predict the clinical course of depression and hence generate the best treatment and service. The featuring symptoms of the atypical feature include mood reactivity, two or more of this symptoms: 1) increased appetite, 2) increased sleep, 3) leaden paralysis and 4) interpersonal rejection sensitivity and should not have melancholic or catatonic features of depression.[A31917] Neurotic depression is a depression of an emotionally unstable person. It is a secondary condition to major personality disorder, neuroses and drug use disorders. Likewise, a primary depression with a family history of depression spectrum disease would fit in this category.[A31922] A nonendogenous depression is characterized by a disturbance in mood and general outlook. The physical symptoms tend to be less severe and it often occurs in response to stressful life events that keep occurring over a large period of time generating a continuous stress in the daily living.[A31924]
DB00784Mefenamic acidFor the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
DB00788NaproxenFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. Also for the relief of mild to moderate pain and the treatment of primary dysmenorrhea.
DB00794PrimidonePrimidone is commonly indicated for the management of grand mal, psychomotor, and focal epileptic seizures [L4645, FDA Label]. In addition, it has also been studied and utilized as an effective management of essential tremor [A39414, A39415, L4645].
DB00795SulfasalazineFor the treatment of Crohn's disease and rheumatoid arthritis as a second-line agent.
DB00801HalazepamUsed to relieve anxiety, nervousness, and tension associated with anxiety disorders.
DB00802AlfentanilFor the management of postoperative pain and the maintenance of general anesthesia.
DB00805MinaprineFor the treatment of depression
DB00807ProparacaineUsed as a local (ophthalmic) anesthetic.
DB00810BiperidenFor use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.
DB00812PhenylbutazoneFor the treatment of backache and ankylosing spondylitis
DB00813FentanylFor the treatment of cancer patients with severe pain that breaks through their regular narcotic therapy.
DB00814MeloxicamFor symptomatic treatment of arthritis and osteoarthritis.
DB00818PropofolUsed for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
DB00819AcetazolamideFor adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma
DB00821CarprofenFor use as a pain reliever in the treatment of joint pain and post-surgical pain.
DB00822DisulfiramFor the treatment and management of chronic alcoholism
DB00829DiazepamIn general, diazepam is useful in the symptomatic management of mild to moderate degrees of anxiety in conditions dominated by tension, excitation, agitation, fear, or aggressiveness such as may occur in psychoneurosis, anxiety reactions due to stress conditions, and anxiety states with somatic expression [F3160]. Moreover, in acute alcoholic withdrawal, diazepam may be useful in the symptomatic relief of acute agitation, tremor, and impending acute delirium tremens [F3160]. Furthermore, diazepam is a useful adjunct for the relief of skeletal muscle spasm due to reflex spasm to local pathologies, such as inflammation of the muscle and joints or secondary to trauma; spasticity caused by upper motor neuron disorders, such as cerebral palsy and paraplegia; athetosis and the rare "stiff man syndrome" [F3160]. Particular label information from the United Kingdom also lists particular age-specific indications, including for adults: (1) The short-term relief (2-4 weeks) only, of anxiety which is severe, disabling, or subjecting the individual to unacceptable distress, occurring alone or in association with insomnia or short-term psychosomatic, organic or psychotic illness, (2) cerebral palsy, (3) muscle spasm, (4) as an adjunct to certain types of epilepsy (eg. myoclonus), (5) symptomatic treatment of acute alcohol withdrawal, (6) as oral premedication for the nervous dental patient, and (7) for premedication before surgery [L5188]. In the same UK label information, diazepam is indicated in children for: (1) control of tension and irritability in cerebral spasticity in selected cases, (2) as an adjunct to the control of muscle spasm in tetanus, and for (3) oral premedication [L5188].
DB00830PhenmetrazineUsed as an anorectic in the treatment of obesity.
DB00831TrifluoperazineFor the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
DB00837ProgabideIndicated for the treatment of epilepsy.
DB00842OxazepamFor the treatment of anxiety disorders and alcohol withdrawal.
DB00843DonepezilFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
DB00844NalbuphineFor the relief of moderate to severe pain.
DB00849MethylphenobarbitalFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
DB00850PerphenazineFor use in the management of the manifestations of psychotic disorders and for the control of severe nausea and vomiting in adults.
DB00854LevorphanolFor the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate.
DB00856ChlorphenesinUsed, along with rest and physical therapy, to treat injuries and other painful muscular conditions. Investigated for use in trigeminal neuralgia (tic douloureux), a neuropathic disorder characterized by severe facial pain. Was investigated as a modulator of histamine release.
DB00861DiflunisalFor symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis.
DB00865BenzphetamineFor the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction
DB00868BenzonatateFor the symptomatic relief of cough. Has also been applied locally in the oral cavity in adults by releasing the drug from the liquid-filled capsules to provide oropharyngeal anesthesia for conscious intubation.
DB00870SuprofenUsed as eye drops to inhibit the miosis (pupil constriction) that may occur during ocular surgery.
DB00875FlupentixolFor use in the treatment of schizophrenia and depression
DB00889GranisetronFor the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy (including high dose cisplatin), postoperation, and radiation (including total body irradiation and daily fractionated abdominal radiation).
DB00892OxybuprocaineUsed to temporarily numb the front surface of the eye so that the eye pressure can be measured or a foreign body removed.
DB00897TriazolamFor the short-term treatment of insomnia.
DB00898EthanolFor therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical procedures are contraindicated.
DB00899RemifentanilFor use during the induction and maintenance of general anesthesia.
DB00904OndansetronIn the adult patient population: i) orally administered ondansetron tablets and orally disintegrating tablets (ODT) are indicated for: - the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including high dose (ie. greater than or equal to 50 mg/m2) cisplatin therapy, and radiotherapy, and - the prevention and treatment of postoperative nausea and vomiting ii) intravenously administered ondansetron injection formulations are indicated for: - the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, including high dose (ie. greater than or equal to 50 mg/m2) cisplatin therapy, and - the prevention and treatment of postoperative nausea and vomiting In the pediatric (4-18 years of age) patient population: i) ondansetron was effective and well tolerated when given to children 4-12 years of age for the treatment of post-chemotherapy induced nausea and vomiting, ii) ondansetron tablets, ondansetron ODT, ondansetron injection are not indicated for the treatment of children 3 years of age or younger, iii) ondansetron tablets, ondansetron ODT, ondansetron injection are not indicated for use in any age group of the pediatric population for the treatment of post-radiotherapy induced nausea and vomiting, and iV) ondansetron tablets, ondansetron ODT, ondansetron injection are not indicated for use in any age group of the pediatric population for the treatment of postoperative nausea and vomiting In the geriatric (>65 years of age) patient population: i) efficacy and tolerance of ondansetron were similar to that observed in younger adults for the treatment of post-chemotherapy and radiotherapy-induced nausea and vomiting, and ii) clinical experience in the use of ondansetron in the prevention and treatment of postoperative nausea and vomiting is limited and is not indicated for use in the geriatric patient population
DB00906TiagabineFor the treatment of partial seizures
DB00907CocaineFor the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
DB00909ZonisamideFor use as adjunctive treatment of partial seizures in adults with epilepsy.
DB00915AmantadineFor the chemoprophylaxis, prophylaxis, and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Also for the treatment of parkinsonism and drug-induced extrapyramidal reactions.
DB00921BuprenorphineFor the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.
DB00924CyclobenzaprineFor use as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.
DB00933MesoridazineUsed in the treatment of schizophrenia, organic brain disorders, alcoholism and psychoneuroses.
DB00934MaprotilineFor treatment of depression, including the depressed phase of bipolar depression, psychotic depression, and involutional melancholia, and may also be helpful in treating certain patients suffering severe depressive neurosis.
DB00936Salicylic acidKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
DB00937DiethylpropionUsed in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
DB00939Meclofenamic acidFor the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
DB00949FelbamateFor use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and/or liver failure is deemed acceptable in light of the benefits conferred by its use.
DB00956HydrocodoneFor relief of moderate to moderately severe pain. Also used for the symptomatic relief of nonproductive cough, alone or in combination with other antitussives or expectorants.
DB00959MethylprednisoloneAdjunctive therapy for short-term administration in rheumatoid arthritis.
DB00961MepivacaineFor production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.
DB00962ZaleplonFor the treatment of short-term treatment of insomnia in adults.
DB00963BromfenacFor the treatment of postoperative inflammation in patients who have undergone cataract extraction.
DB00985DimenhydrinateDimenhydrinate is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
DB00986GlycopyrroniumFor use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and free acidity of gastric secretions and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. Also used to treat chronic obstructive pulmonary disease (COPD).
DB00989RivastigmineFor the treatment of mild to moderate dementia associated with Parkinson's disease or of the Alzheimer's type.
DB00991OxaprozinUsed to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.
DB00996GabapentinFor the management of postherpetic neuralgia in adults and as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy.
DB01002LevobupivacaineFor the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management
DB01009KetoprofenFor symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.
DB01014BalsalazideFor the treatment of mildly to moderately active ulcerative colitis.
DB01028MethoxyfluraneFor use in the induction and maintenance of general anesthesia
DB01037SelegilineMonotherapy for initial treatment of Parkinson's disease, as well as an adjunct therapy in patients with a decreased response to levodopa/carbadopa. Also used for the palliative treatment of mild to moderate Alzheimer's disease and at higher doses, for the treatment of depression.
DB01043MemantineMemantine is used to manage moderate to severe Alzheimer's dementia [FDA label]. A more recent systemic review and meta-analysis [A177106] indicates that memantine is beneficial as a first line drug for the treatment of Alzheimer's dementia. Cholinesterase inhibitors may be added to memantine for further beneficial effects on behavioral symptoms and other symptoms of dementia [A177106].
DB01049Ergoloid mesylateIt was labeled by the FDA for the treatment of symptoms of an idiopathic decline in the mental capacity not related to a potentially reversible condition[A32913] as well as for age-related cognitive impairment.[A32926] The prescription of this drug is conditioned to the corroboration that the patient is not suffering from a potentially reversible and treatable condition especially delirium and dementiform illness secondary to systemic disease, primary neurological disease or primary mood disturbance.[L2637] To know more about the individual components of the ergoloid mixture, please visit [DB13345] and [DB11274]
DB01050IbuprofenIbuprofen is the most commonly used and prescribed NSAID. It is very common over the counter medication widely used as an analgesic, anti-inflammatory and antipyretic.[A39096] The use of ibuprofen and its enantiomer [DB09213] in a racemic mix is common for the management of mild to moderate pain related to dysmenorrhea, headache, migraine, postoperative dental pain, spondylitis, osteoarthritis, rheumatoid arthritis, and soft tissue disorder.[A39097] Due to its activity against prostaglandin and thromboxane synthesis, ibuprofen has been attributed to alteration of platelet function and prolongation of gestation and labor.[A39092] As ibuprofen is a widely used medication, the main therapeutic indications are: * Patent Ductus Arteriosus - it is a neonatal condition wherein the ductus arteriosus (blood vessel that connects the main pulmonary artery to the proximal descending aorta) fails to close after birth causing severe risk of heart failure. The prostaglandin inhibition of ibuprofen has been studied for the treatment of this condition as it is known that prostaglandin E2 is responsible for keeping the ductus arteriosus open.[A39100] * Rheumatoid- and osteo-arthritis - ibuprofen is very commonly used in the symptomatic treatment of inflammatory, musculoskeletal and rheumatic disorders.[A39176] * Cystic fibrosis - the use of high dosages of ibuprofen has been proven to decrease inflammation and decreasing polymorphonuclear cell influx in the lungs.[A39177] * Orthostatic hypotension - ibuprofen can induce sodium retention and antagonize the effect of diuretics which has been reported to be beneficial for patients with severe orthostatic hypotension.[A1651] * Dental pain - ibuprofen is used to manage acute and chronic orofacial pain.[A10901] * Minor pain - ibuprofen is widely used to reduce minor aches and pains as well as to reduce fever and manage dysmenorrhea. It is very commonly used for the relief of acute indications such as fever and tension headaches.[A39092] * Investigational uses - efforts have been put into developing ibuprofen for the prophylaxis of Alzheimer's disease, Parkinson disease, and breast cancer.[A39092]
DB01065MelatoninUsed orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that melatonin is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for this use. A number of studies have shown that melatonin may be effective for treating sleep-wake cycle disturbances in children and adolescents with mental retardation, autism, and other central nervous system disorders. It appears to decrease the time to fall asleep in children with developmental disabilities, such as cerebral palsy, autism, and mental retardation. It may also improve secondary insomnia associated with various sleep-wake cycle disturbances. Other possible uses for which there is some evidence for include: benzodiazepine withdrawal, cluster headache, delayed sleep phase syndrome (DSPS), primary insomnia, jet lag, nicotine withdrawal, preoperative anxiety and sedation, prostate cancer, solid tumors (when combined with IL-2 therapy in certain cancers), sunburn prevention (topical use), tardive dyskinesia, thrombocytopenia associated with cancer, chemotherapy and other disorders.
DB01068ClonazepamClonazepam is indicated as monotherapy or as an adjunct in the treatment of Lennox-Gastaut syndrome (petit mal variant), akinetic, and myoclonic seizures [FDA Label] [F3787]. Furthermore, clonazepam may also be of some value in patients with absence spells (petit mal) who have failed to respond to succinimides [FDA Label] [F3787]. Additionally, clonazepam is also indicated for the treatment of panic disorder, with or without agoraphobia, as defined in the DSM-V [FDA Label]. Alternatively, some regional prescribing information note that clonazepam is indicated for all clinical forms of epileptic disease and seizures in adults, especially absence seizures (petit mal) including atypical absence; primary or secondarily generalised tonic-clonic (grand mal), tonic or clonic seizures; partial (focal) seizures with elementary or complex symptomatology; various forms of myoclonic seizures, myoclonus and associated abnormal movements [L5572, F3796]. Such regional label data also has clonazepam indicated for most types of epilepsy in infants and children, especially absences (petit mal), myoclonic seizures and tonic-clonic fits, whether due to primary generalized epilepsy or to secondary generalization of partial epilepsy [F3796].
DB01075DiphenhydramineDiphenhydramine is a first-generation histamine H1 receptor antagonist (H1 antihistamine) that is widely available as a non-prescription, over-the-counter (OTC) medication. As an OTC medication, diphenhydramine is typically formulated as tablets and creams indicated for use in treating sneezing, runny nose, itchy/watery eyes, itching of nose or throat, insomnia, pruritis, urticaria, insect bites/stings, allergic rashes, and nausea [L5263, L5266, L5269, F3379, A174541]. Additionally, when the use of oral diphenhydramine is impractical, there are also prescription-only formulations such as diphenhydramine injection products that are effective in adults and pediatric patients (other than premature infants and neonates) for: i) the amelioration of allergic reactions to blood or plasma, in anaphylaxis as an adjunct to epinephrine and other standard measures after acute allergic reaction symptoms have been controlled, and for other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated [F3352]; ii) the active treatment of motion sickness [F3352]; and iii) use in parkinsonism when oral therapy is impossible or contraindicated, as follows: parkinsonism in the elderly who are unable to tolerate more potent agents; mild cases of parkinsonism in other age groups, and in other cases of parkinsonism in combination with centrally acting anticholinergic agents [F3352].
DB01080VigabatrinFor use as an adjunct in treatment resistant epilepsy, refractory complex partial seizures, and secondary generalized seizures. It is also used as monotherapy in infantile spasms in West syndrome.
DB01081DiphenoxylateFor as adjunctive therapy in the management of diarrhea
DB01083OrlistatFor obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Also used to reduce the risk for weight regain after prior weight loss. Use of orlistat is pending revision due to reports of liver-related adverse events.
DB01086BenzocaineFor general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex.
DB01100PimozideUsed for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.
DB01104SertralineFor the management of major depressive disorder (MDD), posttraumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD) with or without agoraphobia, premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD) [FDA Label]. It may be used for premature ejaculation and vascular headaches as off-label indications.
DB01105SibutramineFor the treatment of obesity.
DB01116TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
DB01142DoxepinOral doxepin is approved for the following indications: - Treatment of depression and/or anxiety.[A177163] - Treatment of depression and/or anxiety associated with different conditions, including alcoholism, organic disease and manic-depressive disorders.[T249] - Treatment of psychotic depressive disorders with associated anxiety.[T249] - Treatment of involutional depression.[T249] - Treatment of manic-depressive disorder.[T249] - Treatment of insomnia characterized by difficulties with sleep maintenance.[A177163] Topical doxepin is also approved for short-term (up to 8 days) management of moderate pruritus in adult patients with atopic dermatitis, pruritus or lichen simplex chronicus.[T249] Off-label, doxepin is used topically for the management of neuropathic pain.[A177172] Depression is a common medical illness that causes feelings of sadness and or loss of interest in prior enjoyable activities. This condition can lead to emotional and physical disturbances that can decrease the ability of a person to function in a regular environment.[L5980] Anxiety is a normal reaction of the body towards a normal danger. When the anxious state is exacerbated or appears on situations without danger, it is defined as an anxiety disorder. This disorders can appear in different forms such as phobias, panic, obsessive-compulsive disorder and post-traumatic stress disorder.[L5983] Insomnia is a sleep disorder that directly affects the quality of life of the individual. It is characterized by the complication either to fall asleep or to stay asleep. This condition can be occasional or chronic.[L5986] Pruritus is defined as an unpleasant skin reaction that provokes the urge to scratch. It can be localized or generalized and it can appear in an acute or chronic manner.[L5989] Neuropathic pain occurs due to the damage or dysfunction of the peripheral or central nervous system rather than stimulation of the pain receptors.[L5992]
DB01149NefazodoneFor the treatment of depression.
DB01151DesipramineFor relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management.
DB01154ThiamylalUsed for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
DB01156BupropionFor the treatment of depression and as aid to smoking cessation.
DB01159HalothaneFor the induction and maintenance of general anesthesia
DB01161ChloroprocaineFor the production of local anesthesia by infiltration and peripheral nerve block. They are not to be used for lumbar or caudal epidural anesthesia.
DB01166CilostazolFor the reduction of symptoms of intermittent claudication (pain in the legs that occurs with walking and disappears with rest).
DB01171MoclobemideFor the treatment of major depressive disorder and bipolar disorder [A31901].
DB01173OrphenadrineIndicated for the treatment of Parkinson's disease.
DB01174PhenobarbitalFor the treatment of all types of seizures except absence seizures.
DB01175EscitalopramLabeled indications include major depressive disorder (MDD) and generalized anxiety disorder (GAD). Unlabeled indications include treatment of mild dementia-associated agitation in nonpsychotic patients.
DB01176CyclizineFor prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
DB01178ChlormezanoneUsed in the management of anxiety and in the treatment of muscle spasm.
DB01183NaloxoneFor the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol. It is also indicated for the diagnosis of suspected acute opioid overdose. It may also be used as an adjunctive agent to increase blood pressure in the management of septic shock.
DB01184DomperidoneFor management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
DB01189DesfluraneFor use as an inhalation agent for induction and/or maintenance of anesthesia for inpatient and outpatient surgery in adults.
DB01192OxymorphoneFor the treatment of moderate-to-severe pain.
DB01198ZopicloneFor the short-term treatment of insomnia.
DB01200BromocriptineFor the treatment of galactorrhea due to hyperprolactinemia, prolactin-dependent menstrual disorders and infertility, prolactin-secreting adenomas, prolactin-dependent male hypogonadism, as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases, as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodopa in advanced cases with motor complications. Bromocriptine has also been used off-label to treat restless legs syndrome and neuroleptic malignant syndrome.
DB01202LevetiracetamUsed as adjunctive therapy in the treatment of partial onset seizures in adults and children 4 years of age and older with epilepsy.
DB01204MitoxantroneFor the treatment of secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis
DB01209DezocineIndicated in the treatment of moderate to severe pain.
DB01215EstazolamFor the short-term management of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings.
DB01219DantroleneFor use, along with appropriate supportive measures, for the management of the fulminant hypermetabolism of skeletal muscle characteristic of malignant hyperthermia crises in patients of all ages. Also used preoperatively, and sometimes postoperatively, to prevent or attenuate the development of clinical and laboratory signs of malignant hyperthermia in individuals judged to be malignant hyperthermia susceptible.
DB01221KetamineKetamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior other general anesthetic agents and as a supplement of low potency agents.[L1336, FDA label] Reports have indicated a potential use of ketamine as a therapeutic tool for the management of depression when administered in lower doses.[A31873] These reports have increased the interest for ketamine in this area and several clinical trials are launched for this indication.[L1337, A31874]
DB01224QuetiapineFor the treatment of schizophrenia and related psychotic disorders.
DB01227LevacetylmethadolFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
DB01230PemolineFor treatment of Attention Deficit Hyperactivity Disorder (ADHD)
DB01231DiphenidolFor use in the prevention and symptomatic treatment of peripheral (labyrinthine) vertigo and associated nausea and vomiting that occur in such conditions as Meniere's disease and surgery of the middle and inner ear. Also for the control of nausea and vomiting associated with postoperative states, malignant neoplasms, labyrinthine disturbances, antineoplastic agent therapy, radiation sickness, and infectious diseases.
DB01233MetoclopramideFor the treatment of gastroesophageal reflux disease (GERD). It is also used in treating nausea and vomiting, and to increase gastric emptying.
DB01234DexamethasoneInjection: for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema.
Ophthalmic ointment and solution: for the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.
Ophthalmic solution only: for the treatment of steroid responsive inflammatory conditions of the external auditory meatus
Topic cream: for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Oral aerosol: for the treatment of bronchial asthma and related corticosteroid responsive bronchospastic states intractable to adequate trial of conventional therapy
Intranasal aerosol: for the treatment of allergic ot inflammatory nasal conditions, and nasal polyps
DB01235LevodopaFor the treatment of idiopathic Parkinson's disease (Paralysis Agitans), postencephalitic parkinsonism, symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication, and manganese intoxication.
DB01236SevofluraneUsed for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.
DB01238AripiprazoleFor the treatment of schizophrenia and related psychotic disorders.
DB01239ChlorprothixeneFor treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
DB01242ClomipramineMay be used to treat obsessive-compulsive disorder and disorders with an obsessive-compulsive component (e.g. depression, schizophrenia, Tourette’s disorder). Unlabeled indications include: depression, panic disorder, chronic pain (e.g. central pain, idiopathic pain disorder, tension headache, diabetic peripheral neuropathy, neuropathic pain), cataplexy and associated narcolepsy (limited evidence), autistic disorder (limited evidence), trichotillomania (limited evidence), onchophagia (limited evidence), stuttering (limited evidence), premature ejaculation, and premenstrual syndrome.
DB01247IsocarboxazidIsocarboxazid is indicated for the treatment of the enduring and debilitating symptoms of depression that have not responded to other antidepressant drugs.[L1372] Depression is a common but serious mood disorder. The patient will present changes in its feelings, thoughts, and ability to handle everyday activities. For a mood disorder to be considered as depression, the symptoms should be present for at least two weeks.[L1375]
DB01250OlsalazineFor the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.
DB01255LisdexamfetamineFor the treatment of Attention-deficit/hyperactivity disorder (ADHD) and for moderate to severe binge eating disorder in adults [FDA label], [A40246]. This drug is not indicated for weight loss. Use of other sympathomimetic drugs for weight loss is associated with serious cardiovascular effects. The safety and effectiveness of this drug for the treatment of obesity have not yet been determined [FDA label].
DB01267PaliperidoneFor the treatment of schizophrenia.
DB01283LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
DB01320FosphenytoinFor the control of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. It can also be substituted, short-term, for oral phenytoin.
DB01351AmobarbitalNot Available
DB01353ButobarbitalFor the treatment of insomnia.
DB01355HexobarbitalFor the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli.
DB01364EphedrineEphedrine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia.
DB01367RasagilineFor the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
DB01397Magnesium salicylateMagnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain
DB01399SalsalateFor relief of the signs and symptoms of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
DB01401Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
DB01403MethotrimeprazineFor the treatment of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
DB01425AlizaprideAlizapride is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
DB01433Methadyl acetateUsed mainly in the treatment of narcotic dependence.
DB01435AntipyrineAntipyrine is an analgesic often used to test effects of other drugs on liver enzymes..
DB01437GlutethimideFor the treatment of insomnia.
DB01440gamma-Hydroxybutyric acidUsed as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance.
DB01445BufotenineNot Available
DB01450DihydroetorphineNot Available
DB01452DiamorphineDiamorphine, as a prescription medication in the United Kingdom, is indicated for use in the treatment of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnoea in acute pulmonary edema [L4999].
DB01454MidomafetamineClinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S.
DB01459BezitramideA narcotic analgesic once used for the treatment of severe chronic pain. [A14383]
DB01463FencamfaminFor the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy.
DB01466EthylmorphineEthylmorphine is an analgesic used for pain relief.
DB014724-MethoxyamphetamineNot Available
DB01482FenethyllineNot Available
DB01483BarbitalNot Available
DB014844-Bromo-2,5-dimethoxyamphetamineNot Available
DB01486CathineUsed to decrease appetite.
DB01488DimethyltryptamineSome people use this compound as a psychedelic inducing agent.
DB01497EtorphineNot Available
DB01509TenamfetamineNot Available
DB01511DelorazepamMainly used as an anti-anxiety agent. Studies have found delorazepam to be more effective in the first 4 weeks of use than antidepressants; however, after 4 weeks, antidepressants showed superior anti-anxiety effects. [Wikipedia] Anti-anxiety effects also appear to be weaker in elderly patients. [1] Effectiveness has also been observed in the treatment of alcohol withdrawal. Delorazapam was reported to be a manageable drug in that it did not exhibit severe side effects and did not require further therapies to control symptoms of withdrawal. [3]
DB01520TenocyclidineBecause of its high affinity for the phencyclidine binding site on the NMDA receptor, the 3H radiolabelled form of tenocyclidine is widely used in research into NMDA receptors.
DB01525EcgonineNot Available
DB01529DextromoramideNot Available
DB01535CarfentanilCarfentanil is similar (but more potent) to the opioid analgesic fentanyl. It is used as a tranquilizer for large animals.
DB01544FlunitrazepamFor short-term treatment of severe insomnias, that are not responsive to other hypnotics.
DB01545Ethyl loflazepateNot Available
DB01547DrotebanolNot Available
DB01548DiprenorphineDiprenorphine is used to reverse the effects of the super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals in veterinary medicine. Not used in humans.
DB01551DihydrocodeineDihydrocodeine is used for the treatment of moderate to severe pain, including post-operative and dental pain [2]. It can also be used to treat chronic pain [1], breathlessness and coughing. In heroin addicts, dihydrocodeine has been used as a substitute drug, in doses up to 2500mg/day to treat addiction. [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014322/]
DB01555AlphacetylmethadolNot Available
DB01558BromazepamFor the short-term treatment of insomnia, short-term treatment of anxiety or panic attacks, if a benzodiazepine is required, and the alleviation of the symptoms of alcohol- and opiate-withdrawal.
DB01560CathinoneNot Available
DB01563Chloral hydrateMainly used as a hyponotic in the treatment of insomnia; however, it is only effective as a hypnotic for short-term use. May be used as a routine sedative preoperatively to decrease anxiety and cause sedation and/or sleep with respiration depression or cough reflex.
DB01565DihydromorphineDihydromorphine is an opioid analgesic used for moderate to severe pain relief.
DB01567FludiazepamUsed for the short-term treatment of anxiety disorders.
DB01570OhmefentanylNot Available
DB015713-MethylfentanylNot Available
DB01576DextroamphetamineDextroamphetamine is indicated for the treatment of attention deficit hyperactivity disorder (ADHD)[Label].
DB01577MetamfetamineFor the treatment of Attention Deficit Disorder with Hyperactivity (ADHD) and exogenous obesity.
DB01579PhendimetrazineUsed in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
DB01580OxprenololUsed in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.
DB01587KetazolamKetazolam could be used for the treatment of anxiety. In approved countries, it is indicated for the treatment of anxiety, tension, irritability and similar stress related symptoms.
DB01588PrazepamFor the treatment of anxiety disorders.
DB01589QuazepamUsed to treat insomnia.
DB01595NitrazepamUsed to treat short-term sleeping problems (insomnia), such as difficulty falling asleep, frequent awakenings during the night, and early-morning awakening.
DB01600Tiaprofenic acidTiaprofenic acid is used to treat pain, especially arthritic pain.
DB01614AcepromazineAcepromazine was first used in humans in the 1950s as an antipsychotic agent. It is now rarely used in humans. Acepromazine is frequently used in animals as a sedative and antiemetic. Its principal value is in quietening and calming anxious animals.
DB01615AceprometazineAceprometazine is often used in combination with meprobamate for the treatment of sleep disorders.
DB01618MolindoneMolindone is used for the management of the manifestations of psychotic disorders.
DB01623ThiothixeneFor the management of schizophrenia.
DB01624ZuclopenthixolUsed in the management of acute psychoses such as mania or schizophrenia. However, the use of zuclopenthixol acetate in psychiatric emergencies as an alternative to standard treatments (haloperidol, clotiapine, etc.) should be cautioned, since well executed and documented trials of zuclopenthixol acetate for this use have yet to be conducted. Zuclopenthixol acetate is not intended for long-term use.
DB01628EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
DB01816CastanospermineNot Available
DB01954RolipramNot Available
DB021053,5-DinitrocatecholNot Available
DB02115DaidzinNot Available
DB022077-NitroindazoleNot Available
DB02709ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
DB02855N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-ProlineNot Available
DB02959OxitriptanFor use as an antidepressant, appetite suppressant, and sleep aid.
DB03575PhencyclidineNot Available
DB03585OxyphenbutazoneNot Available
DB03783PhenacetinUsed principally as an analgesic.
DB04165ValpromideNot Available
DB04166Anthranilic acidNot Available
DB04325PhenethylamineNot Available
DB04552Niflumic acidUsed in the treatment of rheumatoid arthritis.
DB04599AniracetamNot Available
DB04688MethylecgonineNot Available
DB04743NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
DB04812BenoxaprofenNot Available
DB04817MetamizoleUsed in the past as a powerful painkiller and fever reducer.
DB04818IproniazidFor the treatment of depression (originally intended to treat tuberculosis).
DB04819MethapyrileneNot Available
DB04820NialamideNot Available
DB04822OxeladinNot Available
DB04827UrethaneNot Available
DB04828ZomepiracZomepirac was indicated for the management of mild to severe pain.
DB04829Lysergic acid diethylamideNot Available
DB04833MethaqualoneFor the treatment of insomnia, and as a sedative and muscle relaxant.
DB04836AmineptineFor the treatment of depression.
DB04841FlunarizineUsed in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
DB04842FluspirileneUsed for the treatment of schizophrenia.
DB04864Huperzine AInvestigated for use/treatment in alzheimer's disease.
DB04870Oleoyl-estroneFor the treatment of obesity.
DB04872OsanetantPotential therapy for schizophrenia, depression and visceral pain.
DB04894VapreotideFor the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
DB04896MilnacipranMilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for the management of fibromyalgia in patients that are 18 years old or above [F3925]. At the same time, levomilnacipran is indicated for the treatment of major depressive disorder (MDD) in patients that are 18 years old or above [F3922], although some regional prescribing information notes that use of the medication is specifically for the short-term symptomatic relief of MDD [F3919]. Nevertheless, it is important to note that the regulatory approval of and/or indications listed here for milnacipran may or may not exist and/or vary greatly between regions and nations [F3928, F3934].
DB04948LofexidineLofexidine is indicated for mitigation of symptoms associated with acute withdrawal from opioids and for facilitation of the completion of opioid discontinuation treatment. It is the first non-opioid medication for the symptomatic management of opioid discontinuation.[L2801] Opioid withdrawal syndrome is a debilitating manifestation of opioid dependence.[A33085] This condition is extremely unpleasant lasting several days with some of the main features being abdominal pain, nausea, diarrhea, mydriasis, lacrimation, and piloerection. These symptoms are often observed after abrupt reductions in the opioid dose and can be resolved by re-administration of the opioid.[A33088]
DB04951PirfenidoneFor the treatment of idiopathic pulmonary fibrosis (IPF).
DB04953EzogabineAdjuvant treatment of partial-onset seizures.
DB05010SGS-742Investigated for use/treatment in alzheimer's disease, attention deficit/hyperactivity disorder (ADHD), memory loss, and schizophrenia and schizoaffective disorders.
DB05073SRT501Investigated for use/treatment in diabetes mellitus type 2 and neurologic disorders.
DB05173PTC299Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB05232TetrodotoxinFor the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.
DB05246MethsuximideFor the control of absence (petit mal) seizures that are refractory to other drugs.
DB05273Samarium (153Sm) lexidronamInvestigated for use/treatment in bone metastases, multiple myeloma, prostate cancer, and rheumatoid arthritis.
DB05289TarenflurbilInvestigated for use/treatment in alzheimer's disease and prostate cancer.
DB05316PimavanserinInvestigated for use/treatment in neurologic disorders, parkinson's disease, psychosis, schizophrenia and schizoaffective disorders, and sleep disorders.
DB05424CanertinibInvestigated for use/treatment in breast cancer and lung cancer.
DB05676ApremilastInvestigated for use/treatment in psoriasis and psoriatic disorders.
DB05767AndrographolideInvestigated for use/treatment in ulcerative colitis.
DB05791PerflubronInvestigated for use/treatment in cardiac surgery, hemorrhage, and ileus.
DB06144SertindoleUsed in the treatment of schizophrenia.
DB06148MianserinFor the treatment of depression.
DB06153PizotifenIndicated for the prophylactic management of migraines [L2292].
DB06174NoscapineInvestigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.
DB06196IcatibantApproved for use in acute attacks of hereditary angioedema (HAE). Investigated for use/treatment in angioedema, liver disease, and burns and burn infections.
DB06216AsenapineUsed for treatment in psychosis, schizophrenia and schizoaffective disorders, manic disorders, and bipolar disorders as monotherapy or in combination.
DB06218LacosamideLacosamide is indicated for adjunctive therapy for partial onset seizures in patients with epilepsy over 17 years old. Injection is indicated for short term use when oral therapy is not feasible.
DB06230NalmefeneIndicated for the reduction of alcohol consumption in adult patients with alcohol dependence who have a high drinking risk level (DRL), without physical withdrawal symptoms and who do not require immediate detoxification [L1024]. Indicated for the complete or partial reversal of opioid drug effects, including respiratory depression - induced by either natural or synthetic opioids - or in the management of known or suspected opioid overdose [FDA Label].
DB06246ExisulindInvestigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
DB06262DroxidopaFor treatment of neurogenic orthostatic hypotension (NOH) associated with various disorders including Multiple System Atrophy, Familial Amyloid Polyneuropathy, hemodialysis induced hypotension and Parkinson's Disease. Also investigated for use/treatment in neurologic disorders, nephropathy, blood (blood forming organ disorders, unspecified), and dizzy/fainting spells.
DB06264TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
DB06283ZiconotideNot Available
DB06288AmisulprideInvestigated for use/treatment in schizophrenia and schizoaffective disorders, mania in bipolar disorder, and depression.
DB06413ArmodafinilInvestigated for use/treatment in sleep disorders, obstructive sleep apnea, schizophrenia and schizoaffective disorders, depression, and bipolar disorders.
DB06444DexanabinolInvestigated for use/treatment in traumatic brain injuries and neurologic disorders.
DB06458RemacemideInvestigated for use/treatment in epilepsy, huntington's disease, and parkinson's disease.
DB06470ClomethiazoleInvestigated for use/treatment in strokes.
DB06479PropentofyllineInvestigated for use/treatment in alzheimer's disease.
DB06512DeramciclaneInvestigated for use/treatment in anxiety disorders.
DB06527TramiprosateInvestigated for use/treatment in strokes and alzheimer's disease.
DB06554GaboxadolInvestigated for use/treatment in sleep disorders and insomnia.
DB06579AdipiplonInvestigated for use/treatment in insomnia and sleep disorders.
DB06582DextofisopamInvestigated for use/treatment in irritable bowel syndrome (IBS).
DB06594AgomelatineAgomelatine is indicated for the treatment of major depressive episodes in adults.
DB06618CutamesineInvestigated for use/treatment in strokes and depression.
DB06623FlupirtineInvestigated for use/treatment in fibromyalgia.
DB06634CasopitantInvestigated for use/treatment in urinary incontinence and adverse effects (chemotherapy).
DB06678EsmirtazapineInvestigated for use/treatment in insomnia and sleep disorders.
DB06684VilazodoneVilazodone is approved for treatment of major depressive disorder[Label,A38477,A177622].
DB06690Nitrous oxideNot Available
DB06700DesvenlafaxineDesvenlafaxine is indicated for the treatment of major depressive disorder in adults[A6990,A6991,Label].
DB06701DexmethylphenidateDexmethylphenidate is used as a treatment for ADHD, ideally in conjunction with psychological, educational, behavioral or other forms of treatment[A177187,Label].
DB06716FospropofolFor monitored anaesthesia care sedation in patients undergoing diagnostic procedures like bronchoscopy and colonscopy or minor surgical procedures like arthroscopy and bunionectomy.
DB06717FosaprepitantFor the prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy.
DB06725LornoxicamFor the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.
DB06736Aceclofenac Indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
DB06737ZaltoprofenNot Available
DB06738KetobemidoneFor the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
DB06739SeratrodastNot Available
DB06750Ginsenoside Rg1Not Available
DB06751DrotaverineUsed in the treatment of functional bowel disorders and alleviating pain in renal colic.
DB06770Benzyl alcoholUlesfia (benzyl alcohol) lotion is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia Lotion does not have ovicidal activity.
DB06778Cupric sulfateElemental use in copper deficiency [L1823] Copper and copper containing compounds are broadly used in medical practice. Metallic copper is used already for many years in dental fillings and in copper intrauterine devices (IUD) for reversible contraception. Ointments containing copper, which release copper ions that are absorbed by the skin in the management of cramps, disturbances of renal function, peripheral, venous hypostatic circulatory disturbances, rheumatic disease and swelling associated with trauma. There are also cosmetic facial creams containing copper as their main active ingredient [L1828].
DB06800MethylnaltrexoneTreatment of opioids induced constipation in palliative patients that are inadequately responding to laxative therapy.
DB06802NepafenacFor the treatment of pain and inflammation associated with cataract surgery.
DB07402AzapropazoneNot Available
DB07477FelbinacNot Available
DB07615TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DB07720EpibatidineNot Available
DB07744Z-Val-Ala-Asp fluoromethyl ketoneNot Available
DB07767Ferulic acidNot Available
DB08329SulthiameNot Available
DB08439ParecoxibUsed for short term perioperative pain control.
DB08796PipazethateFor the treatment of cough.
DB08797SalicylamideNot Available
DB08811TofisopamFor the treatment of anxiety and alcohol withdrawal.
DB08815LurasidoneTreatment of schizophrenia.
DB08842AcetylcarnitineAcetylcarnitine is not approved for any indication in the United states and Canada, but it is approved and indicated in Italy for cerebrovascular disorders, mental function disorders, peripheral nerve disorders, diabetic neuropathy, and nutritional supplementation; Portugal for mental function disorders; Argentina for cerebral vasculopathy, nutritional supplementation, and peripheral neuropathy; Chile for dementia; Philippines for cerebrovascular disorders and mental function disorders; Australia for nutritional supplementation; and India for nutritional supplementation to increase sperm count. Acetylcarnitine also has several potential therapeutic indications for which it is still being investigated: in Norway, acetylcarnitine is in a phase IV trial for prophylactic treatment of migraines; in Italy acetylcarnitine is in a phase II trial for use in patients with type 2 Diabetes Mellitus, a phase III trial for alleviating fatigue in patients with chronic hepatitis C, and for use in patients with Minimal Hepatic Encephalopathy; in the United States acetylcarnitine is in a phase II trial for the neurodegenerative disorder Progressive Supranuclear Palsy, a phase II and III trial for reducing peripheral neuropathy in cancer patients as an adjunct to chemotherapy, a phase I and II trial for treating patients in septic shock, a phase II trial for bipolar depression, a phase II trial to reduce oxidative stress in patients with Sickle Cell disease, a phase I and II trial for chronic fatigue syndrome, and a study for preventing nerve damage in HIV patients; in China acetylcarnitine is in a phase III trial for reducing peripheral neuropathy in cancer patients as an adjunct to chemotherapy; in the United Kingdom acetylcarnitine is being investigated for preventing nerve damage in HIV patients; and in Israel acetylcarnitine is being studied for the treatment of male infertility.
DB08861DPDPENot Available
DB08880TeriflunomideUsed in the treatment of relapsing forms of multiple sclerosis (MS).
DB08892Arbaclofen PlacarbilInvestigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD.
DB08918LevomilnacipranLevomilnacipran is a serotonin and norepinephrine reuptake inhibitor and is indicated for the treatment of major depressive disorder (MDD).
DB08922PerospironeFor the treatment of schizophrenia and acute cases of bipolar mania.
DB08927AmperozideNot Available
DB08940KebuzoneNot Available
DB08942IsoxicamNot Available
DB08944IsoaminileNot Available
DB08951IndoprofenNot Available
DB08953IndalpineNot Available
DB08955IbuproxamNot Available
DB08968FominobenNot Available
DB08969FlurothylNot Available
DB08976FloctafenineNot Available
DB08981FenbufenNot Available
DB08984EtofenamateNot Available
DB08986EtifoxineNot Available
DB08987EtidocaineNot Available
DB08991EpirizoleNot Available
DB08992EperisoneNot Available
DB08997DexetimideNot Available
DB09004ClobutinolNot Available
DB09009ArticaineNot Available
DB09017BrotizolamBrotizolam is indicated for the short-term treatment (2-4 weeks) of severe or debilitating insomnia.
DB09018BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the GI tract.
DB09022BenfluorexNot Available
DB09023BenactyzineNot Available
DB09049NaloxegolIndicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
DB09068VortioxetineVortioxetine is indicated for the treatment of major depressive disorder (MDD).
DB09072Sodium oxybateFor the treatment of cataplexy in narcolepsy and excessive daytime sleepiness (EDS) in narcolepsy.
DB09085TetracaineThe combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.
DB09117ParaldehydeParaldehyde was used historically as a sedative and hypnotic [A19735]. It has been used in the treatment of seizures as an anticonvulsant [A19736].
DB09118StiripentolIndicated for use in conjunction with clobazam and valproate as adjunctive therapy of refractory generalized tonic-clonic seizures in patients with severe myoclonic epilepsy in infancy (SMEI, Dravet’s syndrome) whose seizures are not adequately controlled with clobazam and valproate.
DB09166EtizolamIndicated for the treatment of generalized anxiety disorder with depression, panic disorder and insomnia.
DB09167DosulepinIndicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required.
DB09174LofentanilNot Available
DB09185ViloxazineIndicated for the treatment of clinical depression.
DB09209PholcodinePholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."[L1200] Cough is the respiratory movement that occurs after an irritation signal is transmitted to the central nervous system and further stimulates the medulla oblongata. This stimulation causes a motor output that is sent through motoneurons to the respiratory muscles. A non-productive cough is a type of cough characterized by the absence of sputum, and it has a large inspiration that will cause continuous coughing.
DB09210PiracetamIndicated in adult patients suffering from myoclonus of cortical origin, irrespective of aetiology, and should be used in combination with other anti-myoclonic therapies [L1125].
DB09212LoxoprofenLoxoprofen is non-steroidal anti-inflammatory medication (NSAID) indicated for pain and inflammation related to musculoskeletal and joint disorders [L1226]. In addition to its effects on pain, it is an antipyretic and anti-inflammatory medication [L1227].
DB09215DroxicamDroxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis [L1119].
DB09216Tolfenamic AcidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.[L1293]
DB09218ClonixinUsed primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
DB09224MelperoneFor the treatment of schizophrenia, sleep, disorders, agitation and mentally confused states [L1317, L1319, L1322].
DB09225ZotepineZotepine, like other atypical antipsychotics, is considered as the first-line treatment in newly diagnosed schizophrenia. It is usually thought to be an option of choice for managing acute schizophrenic episodes when discussion with the patient is not possible. Zotepine, as an atypical antipsychotic, is used in patients who are suffering unacceptable side effects from conventional antipsychotics or in relapse patients that were inadequately controlled.[T108] It is important to consider that the indications stated above are related to atypical antipsychotics, that zotepine is not currently FDA, Canada or EMA approved and that studies have not shown any additional benefit when compared with other approved atypical antipsychotics.[A31857] Schizophrenia is a chronic and severe mental disorder that affects how a person thinks, feels and behaves. It is usually marked for a loose reality perspective delineated by hallucinations, delusions and thought and movement disorders.[L1320]
DB09244PirlindoleFor the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving a motor vehicle shows many similarities to that of placebo. The drug appears to stimulate the central nervous system, rather than exhibit a sedative effect, like many antidepressants. Because of its selective, reversible inhibition of monoamine oxidase (MAO-A) and short half-life, unpleasant "cheese effects" are avoided. This refers to the effects of consuming tyramine-rich foods, such as cheese while medicated with monoamine oxidase inhibitors, leading to severe headaches and hypertension [L1395]. of The available evidence supports pirlindole as a safe and effective treatment option for the management of depression and fibromyalgia syndrome [L1394].
DB09245ToloxatoneFor the treatment of major depressive disorder.
DB09273DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
DB09286PipamperoneTreatment of chronic psychoses and states of aggressiveness of various origins [L1515].
DB09288PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.[L1511]
DB09289TianeptineUsed primarily in the treatment of major depressive disorder and anxiety [A31969]. It is currently being studied for fibromyalgia pain treatment [L1426].
DB09290RamosetronFor the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males.
DB09307OxaprotilineInvestigated for the treatment of depression.
DB09342PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures [L1591]. It has been combined with procaine to accelerate its onset of action and provide longer-lasting anesthetic effect [L1592]. It was produced for use when amide local anesthetics were contraindicated due to allergy or when several amide anesthetics were unsuccessful [L1592].
DB09345PramocaineIt is indicated for temporary relief of pain and pruritus from minor lip and skin irritations as well as for temporary relief from pain, burning, itching and discomfort associated with hemorrhoids and other anorectal/anogenital disorders.
DB11130OpiumOpium and its derivatives are the most commonly used medications for the treatment of acute and chronic pain. Opium and its alkaloid-derivatives can also be used as tranquilizers, antitussives and in the treatment of diarrhea.[T138] The direct use of opium is not common nowadays but the use of some of its derivatives such as morphine and codeine, as well as the use of a tincture of opium for severe diarrhea can be seen in medical practice.[T139] Illegal use of opium has been registered to be for both recreational and medicinal purposes.[A32182]
DB11148ButambenButamben was indicated for the treatment of chronic pain due to its long-duration effect.[A32663] It is also indicated as a surface anesthetic for skin a mucous membrane and for the relief of pain and pruritus associated with anorectal disorders.[L2445]
DB11186PentoxyverineIndicated as a cough suppressant to relieve cough caused by the common cold, flu, bronchitis, and sinusitis [A32160].
DB11198Peppermint oilIndicated for the over-the-counter use for: -the symptomatic relief of minor spasms of the gastrointestinal tract, flatulence and abdominal pain, especially in patients with irritable bowel syndrome. -the temporary relief of itching associated with insect bites, eczema, minor burn, sunburn, minor skin irritations, minor cuts, scrapes, atopic dermatitis and other skin disorders. -the temporary symptomatic relief of mild joint and muscle pain as a local topical analgesic. -the temporary relief of tension-type headache.
DB11304PhenoxyethanolAntimicrobial agent used as a preservative in cosmetics [L2618], [L2619], [L2625].
DB11358Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements.[L1113] It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical mastalgia. These indications do not have sufficient evidence of their effectiveness. It was used for the treatment of atopic dermatitis in the United Kingdom but it is currently withdrawn due to lack of evidence of effectiveness.[A33131]
DB11371AlfaxaloneNot Available
DB11376AzaperoneNot Available
DB11428MedetomidineNot Available
DB11466TepoxalinNot Available
DB11477XylazineNot Available
DB11490NalorphineUsed to reverse opioid overdose.
DB11518FlunixinNot Available
DB11562BicucullineNot Available
DB11609NormethadoneFor use in the treatment of cough when other less potent treatments have failed [FDA Label].
DB11632OpicaponeOpicapone is approved as an adjunctive therapy in adults with Parkinson’s disease and end-of-dose motor fluctuations whose symptoms cannot be stabilized on levodopa/dopa decarboxylase inhibitor combinations [L2336].
DB11664PsilocybineNot Available
DB11672CurcuminNo approved therapeutic indications.
DB11699TropisetronFor the prevention of nausea and vomiting induced by cytotoxic therapy and postoperative.
DB11785AnisodamineNot Available
DB11859BrexanoloneBrexanolone is a synthetic neuroactive steroid gamma-aminobutyric acid A (GABA(a)) receptor positive modulator indicated for the treatment of postpartum depression (PPD) in adult women [FDA Label][A176080, A176083, F4063, F4066, F4072].
DB11868EtiracetamNot Available
DB12093TetrahydropalmatineNot Available
DB12094SemapimodNot Available
DB12111MK-212Not Available
DB12116Epigallocatechin gallateNot Available
DB12131VinpocetineNot Available
DB12160BucillamineNot Available
DB12184GepironeNot Available
DB12273EcopipamNot Available
DB12293NefopamNot Available
DB12308EltanoloneNot Available
DB12401BromperidolNot Available
DB12406LisofyllineNot Available
DB12436VofopitantNot Available
DB12445NitroaspirinNot Available
DB12449TempolNot Available
DB12472LevodropropizineNot Available
DB12478PiribedilNot Available
DB12492PiritramideNot Available
DB12518RacloprideNot Available
DB12543SamidorphanNot Available
DB12545IndobufenNot Available
DB12554MebeverineNot Available
DB12590IndiplonNot Available
DB12598NafamostatUsed as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement therapy and extra corporeal membrane oxygenation.
DB12617MizoribineNot Available
DB12618ApocyninNot Available
DB12693RitanserinNot Available
DB12704SpiradolineNot Available
DB12710PerazineNot Available
DB12749ButylphthalideNot Available
DB12779HigenamineNot Available
DB12783BenserazideThe primary therapeutic use for which benserazide is currently indicated for is as a combination therapy with levadopa for the treatment of Parkinson's disease in adults > 25 years of age, with the exception of drug-induced parkinsonism [F2, L2553]. At certain doses, the combination product of levodopa and benserazide may also be used to treat restless legs syndrome, which is sometimes associated with Parkinson's disease [L2553, T181]. There have also been some studies that have prompted the European Medicines Agency to confer orphan designation upon benserazide hydrochloride as a potential therapy for beta thalassaemia [F3]. Although studies are ongoing, no evidence has been formally elucidated as of yet [F3].
DB12833TandospironeNot Available
DB12867BenperidolNot Available
DB12869EliprodilNot Available
DB12930OpipramolNot Available
DB12947DoxifluridineNot Available
DB12972SepranoloneNot Available
DB13001TinoridineNot Available
DB13014HypericinNot Available
DB13025TiaprideTiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly.
DB13050TirilazadNot Available
DB13063ParthenolideNot Available
DB13082NefiracetamNot Available
DB13096GacyclidineNot Available
DB13116NorfluraneNot Available
DB13131SerrapeptaseNot Available
DB13160AlphaprodineNot Available
DB13167AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
DB13203BamifyllineNot Available
DB13217FentiazacNot Available
DB13225DibenzepinNot Available
DB13227TribenosideNot Available
DB13232SuxibuzoneNot Available
DB13233AlaproclateNot Available
DB13234PropanididNot Available
DB13259Ethyl chlorideNot Available
DB13293IpecacIpecac is indicated as an emetic agent for the induction of vomiting in poisoning victims who ingested systemic poison in order to prevent absorption of the chemicals through the gastrointestinal tract. In low doses, ipecac was also used as an expectorant.[L2753] Reports have suggested that ipecac was vastly used in patients with eating disorders to produce vomiting.[T49]
DB13314AlminoprofenNot Available
DB13323TrichloroethyleneNot Available
DB13346BufexamacIndicated for the treatment of various skin conditions, such as atopic eczema and other inflammatory dermatoses.
DB13352DeanolNot Available
DB13411LofepramineNot Available
DB13501BendazacPrior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the prescription medication bendazac lysine for the indication of managing the level of vision in patients with mild to moderate cataracts to facilitate delaying the need for surgical intervention [A39863, A39869, A39890]. Elsewhere bendazac may still be available in a limited capacity as a non-prescription topical cream product for treating conditions like local pain, inflammation, dermatitis, eczema, pruritis, hives, insect bites, burns, erythema, and others [L4780] - although such products may also be facing general discontinuation [L4781].
DB13514PranoprofenNot Available
DB13524PropyphenazoneNot Available
DB13538GuacetisalNot Available
DB13544EthenzamideNot Available
DB13550BifemelaneNot Available
DB13583MephenesinMephenesin was used for the treatment of muscle spasticity in diseases like Parkinson's or Multiple Sclerosis.
DB13612Carbaspirin calciumNot Available
DB13643LoprazolamNot Available
DB13648AlcuroniumNot Available
DB13657BenorilateNot Available
DB13783AcemetacinAcemetacin is not FDA, Canada or EMA approved, but in the countries where it is marketed it is indicated for the symptomatic treatment of pain and swelling in acute inflammation of the joints in rheumathoid arthritis, osteoarthritis, low back pain and post-surgical pain.[L1045] It is also indicated for the treatment of chronic inflammation of the joints in presence of rheumatoid arthritis, treatment of ankylosing spondylitis, treatment of irritation in the joints and spinal column caused by degenerative disorders, treatment of inflammatory soft-tissue rheumatism syndrome and painful swelling and inflammation caused by injury.[L1044, L1046]
DB13791PenfluridolNot Available
DB13841ClopenthixolNot Available
DB13863FosfructoseNot Available
DB13872LormetazepamFor the treatment of short-term insomnia [L927]
DB13875HarmalineNot Available
DB13950WIN 55212-2Not Available
DB13984CyclopropaneNot Available
DB13991PipequalineNot Available
DB14026Thiosalicylic acidNot Available
DB14028NordazepamNot Available
DB14043PalmidrolNot Available
DB14044Hopantenic acidNot Available
DB14059SC-236Not Available
DB14060NS-398Not Available
DB14185Aripiprazole lauroxilAripiprazole lauroxil is indicated for the treatment of schizophrenia and related psychotic disorders.
DB14509Lithium carbonateLithium is used as a mood stabilizer, and is indicated for the treatment of manic episodes and maintenance of bipolar disorder[FDA Label].
DB14644Methylprednisolone hemisuccinateNot Available
DB14682DextrorphanNot Available
DB14719BentazepamNot Available
DB02224TaxifolinNot Available
DB02234S-EthylisothioureaNot Available
DB04017ClorgilineNot Available
DB12153CiticolineNot Available
DB12480Betulinic AcidNot Available
DB12610EbselenNot Available
DB01430AlmitrineFor the treatment of chronic obstructive pulmonary disease.
DB14754SolriamfetolSolriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744].
DrugDrug NameTargetType
DB00042Botulinum Toxin Type BVesicle-associated membrane protein 1target
DB00042Botulinum Toxin Type BVesicle-associated membrane protein 2target
DB00042Botulinum Toxin Type BSynaptotagmin-2target
DB00122CholineCholine-phosphate cytidylyltransferase Btarget
DB00122CholineCholine-phosphate cytidylyltransferase Atarget
DB00122CholinePhospholipase D2target
DB00122CholinePhospholipase D1target
DB00122CholinePhosphoethanolamine/phosphocholine phosphatasetarget
DB00122CholineSolute carrier family 22 member 2transporter
DB00122CholineSolute carrier family 22 member 1transporter
DB00122CholineSolute carrier family 22 member 3transporter
DB00122CholineSolute carrier family 22 member 5transporter
DB00122CholineSolute carrier family 22 member 4transporter
DB00122CholineCholine/ethanolaminephosphotransferase 1enzyme
DB00122CholineCholine transporter-like protein 1transporter
DB00122CholineCholine transporter-like protein 4transporter
DB00122CholineCholine transporter-like protein 2transporter
DB00122CholineCholine transporter-like protein 3transporter
DB00122CholineCholine/ethanolamine kinaseenzyme
DB00122CholineCholine O-acetyltransferaseenzyme
DB00122CholineCholine kinase alphaenzyme
DB00122CholineCholine dehydrogenase, mitochondrialenzyme
DB00122CholineHigh affinity choline transporter 1transporter
DB00122CholineNeuronal acetylcholine receptor subunit alpha-7target
DB00150L-TryptophanTryptophan--tRNA ligase, cytoplasmictarget
DB00150L-TryptophanTryptophan--tRNA ligasetarget
DB00150L-TryptophanTryptophan--tRNA ligase, mitochondrialtarget
DB00150L-TryptophanTryptophan 2,3-dioxygenaseenzyme
DB00150L-TryptophanAromatic-L-amino-acid decarboxylaseenzyme
DB00150L-TryptophanMonocarboxylate transporter 8transporter
DB00150L-TryptophanMonocarboxylate transporter 10transporter
DB00150L-TryptophanTryptophan--tRNA ligaseenzyme
DB00150L-TryptophanTryptophan--tRNA ligase, mitochondrialenzyme
DB00150L-TryptophanTryptophan 5-hydroxylase 1enzyme
DB00150L-TryptophanTryptophan 5-hydroxylase 2enzyme
DB00150L-TryptophanTryptophan--tRNA ligase, cytoplasmicenzyme
DB00150L-TryptophanIndoleamine 2,3-dioxygenase 1enzyme
DB00176FluvoxamineSodium-dependent serotonin transportertarget
DB00176FluvoxamineCytochrome P450 1A2enzyme
DB00176FluvoxamineCytochrome P450 2D6enzyme
DB00176FluvoxamineCytochrome P450 2C9enzyme
DB00176FluvoxamineCytochrome P450 2C19enzyme
DB00176FluvoxamineCytochrome P450 1A1enzyme
DB00176FluvoxamineCytochrome P450 3A4enzyme
DB00176FluvoxamineCytochrome P450 3A5enzyme
DB00176FluvoxamineCytochrome P450 3A7enzyme
DB00176FluvoxamineMultidrug resistance protein 1transporter
DB00176FluvoxamineCytochrome P450 2B6enzyme
DB00176FluvoxamineCytochrome P450 2E1enzyme
DB00176FluvoxaminePotassium voltage-gated channel subfamily H member 2target
DB00176FluvoxamineCytochrome P450 2C8enzyme
DB00176FluvoxamineBile salt export pumptransporter
DB00179MasoprocolArachidonate 5-lipoxygenasetarget
DB00179MasoprocolCytochrome P450 2J2enzyme
DB00179MasoprocolSex hormone-binding globulintarget
DB00181BaclofenGamma-aminobutyric acid type B receptor subunit 1target
DB00181BaclofenGamma-aminobutyric acid type B receptor subunit 2target
DB00182AmphetamineSodium-dependent dopamine transportertarget
DB00182AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
DB00182AmphetamineTrace amine-associated receptor 1target
DB00182AmphetamineCytochrome P450 2D6enzyme
DB00182AmphetamineSolute carrier family 22 member 3transporter
DB00182AmphetamineSolute carrier family 22 member 5transporter
DB00182AmphetamineSynaptic vesicular amine transportertarget
DB00182AmphetamineCytochrome P450 2A6enzyme
DB00182AmphetamineSodium-dependent noradrenaline transportertarget
DB00182AmphetamineAlpha adrenergic receptortarget
DB00182AmphetamineBeta adrenergic receptortarget
DB00182AmphetamineD(2) dopamine receptortarget
DB00182AmphetamineAmine oxidase [flavin-containing] Btarget
DB00182AmphetamineSodium-dependent serotonin transportertarget
DB00182AmphetamineMonoamine oxidasetarget
DB00182Amphetaminevesicular monoamine transporter 2 (VMAT2)target
DB00186LorazepamTranslocator proteintarget
DB00186LorazepamUDP-glucuronosyltransferase 2B15enzyme
DB00186LorazepamGABA-A receptor (anion channel)target
DB00186LorazepamCytochrome P450 3A4enzyme
DB00189EthchlorvynolGABA-A receptor (anion channel)target
DB00190CarbidopaAromatic-L-amino-acid decarboxylasetarget
DB00191PhentermineSodium-dependent noradrenaline transportertarget
DB00191PhentermineSodium-dependent dopamine transportertarget
DB00191PhentermineAmine oxidase [flavin-containing] Atarget
DB00191PhentermineAmine oxidase [flavin-containing] Btarget
DB00191PhentermineSodium-dependent serotonin transportertarget
DB00191PhenterminePro-neuropeptide Ytarget
DB00191PhentermineCytochrome P450 3A4enzyme
DB00193TramadolMu-type opioid receptortarget
DB00193TramadolSodium-dependent noradrenaline transportertarget
DB00193Tramadol5-hydroxytryptamine receptor 2Ctarget
DB00193TramadolKappa-type opioid receptortarget
DB00193TramadolSodium-dependent serotonin transportertarget
DB00193TramadolCytochrome P450 2D6enzyme
DB00193TramadolDelta-type opioid receptortarget
DB00193TramadolCytochrome P450 3A4enzyme
DB00193TramadolCytochrome P450 2B6enzyme
DB00193TramadolGlutamate receptor ionotropic, NMDA 3Atarget
DB00193TramadolAlpha-7 nicotinic cholinergic receptor subunittarget
DB00193TramadolMuscarinic acetylcholine receptor M3target
DB00193TramadolMuscarinic acetylcholine receptor M1target
DB00193TramadolUDP-glucuronosyltransferase 1-1enzyme
DB00193TramadolMultidrug resistance protein 1transporter
DB00201CaffeineAdenosine receptor A1target
DB00201CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB00201CaffeineAdenosine receptor A2atarget
DB00201CaffeineCytochrome P450 1A2enzyme
DB00201CaffeineRyanodine receptor 1target
DB00201CaffeineCytochrome P450 3A4enzyme
DB00201CaffeineCytochrome P450 3A5enzyme
DB00201CaffeineCytochrome P450 3A7enzyme
DB00201CaffeineMultidrug resistance protein 1transporter
DB00201CaffeineCytochrome P450 2E1enzyme
DB00201CaffeineCytochrome P450 2C8enzyme
DB00201CaffeineCytochrome P450 2C9enzyme
DB00201CaffeineCytochrome P450 1A1enzyme
DB00201CaffeineCytochrome P450 1B1enzyme
DB00201CaffeineCytochrome P450 2D6enzyme
DB00201CaffeineCyclic nucleotide phosphodiesterasetarget
DB00201CaffeineDNA-dependent protein kinase catalytic subunittarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
DB00201CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
DB00201CaffeineInositol 1,4,5-trisphosphate receptortarget
DB00201CaffeineSerine-protein kinase ATMtarget
DB00206ReserpineSynaptic vesicular amine transportertarget
DB00206ReserpineMultidrug resistance protein 1transporter
DB00206ReserpineSolute carrier family 22 member 1transporter
DB00206ReserpineBile salt export pumptransporter
DB00206ReserpineCanalicular multispecific organic anion transporter 1transporter
DB00206ReserpineSolute carrier family 22 member 2transporter
DB00206ReserpineCytochrome P450 3A5enzyme
DB00206ReserpineChromaffin granule amine transportertarget
DB00206ReserpineBaculoviral IAP repeat-containing protein 5target
DB00206ReserpineSolute carrier organic anion transporter family member 1B1transporter
DB00206ReserpineSolute carrier organic anion transporter family member 2B1transporter
DB00210AdapaleneRetinoic acid receptor alphatarget
DB00210AdapaleneRetinoic acid receptor RXR-betatarget
DB00210AdapaleneRetinoic acid receptor gammatarget
DB00210AdapaleneRetinoic acid receptor betatarget
DB00210AdapaleneRetinoic acid receptor RXR-gammatarget
DB00210AdapaleneRetinoic acid receptor RXR-alphatarget
DB00210AdapaleneProstaglandin G/H synthase 2target
DB00215CitalopramSodium-dependent serotonin transportertarget
DB00215CitalopramCytochrome P450 2C19enzyme
DB00215CitalopramCytochrome P450 2D6enzyme
DB00215CitalopramCytochrome P450 3A4enzyme
DB00215CitalopramMultidrug resistance protein 1transporter
DB00215CitalopramCytochrome P450 1A2enzyme
DB00215CitalopramHistamine H1 receptortarget
DB00228EnfluraneCalcium-transporting ATPase type 2C member 1target
DB00228EnfluraneGlycine receptor (alpha-1/beta)target
DB00228EnfluraneGlutamate receptor 1target
DB00228EnfluranePotassium voltage-gated channel subfamily A member 1target
DB00228EnfluraneATP synthase subunit delta, mitochondrialtarget
DB00228EnfluraneIntermediate conductance calcium-activated potassium channel protein 4target
DB00228EnfluraneCytochrome P450 2E1enzyme
DB00228EnfluraneSerum albumincarrier
DB00228EnfluraneGABA-A receptor (anion channel)target
DB00230PregabalinExcitatory amino acid transporter 3transporter
DB00230PregabalinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00230PregabalinLarge neutral amino acids transporter small subunit 1transporter
DB00231TemazepamTranslocator proteintarget
DB00231TemazepamCytochrome P450 2C19enzyme
DB00231TemazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00231TemazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00231TemazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00231TemazepamGamma-aminobutyric acid receptor subunit alpha-4target
DB00231TemazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00231TemazepamGamma-aminobutyric acid receptor subunit alpha-6target
DB00231TemazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00231TemazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00231TemazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00231TemazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00231TemazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00231TemazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00231TemazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00231TemazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00231TemazepamGamma-aminobutyric acid receptor subunit pitarget
DB00231TemazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00231TemazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00231TemazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00231TemazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00231TemazepamCytochrome P450 3A4enzyme
DB00231TemazepamCytochrome P450 2B6enzyme
DB00231TemazepamCytochrome P450 2C8enzyme
DB00231TemazepamCytochrome P450 2C9enzyme
DB00231TemazepamGABA-A receptor (anion channel)target
DB00234ReboxetineSodium-dependent noradrenaline transportertarget
DB00234ReboxetineCytochrome P450 3A4enzyme
DB00234ReboxetineCytochrome P450 2D6enzyme
DB00234ReboxetineMultidrug resistance protein 1transporter
DB00237ButabarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00237ButabarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00237ButabarbitalGlutamate receptor 2target
DB00237ButabarbitalGlutamate receptor ionotropic, kainate 2target
DB00237ButabarbitalGABA-A receptor (anion channel)target
DB00245BenzatropineMuscarinic acetylcholine receptor M1target
DB00245BenzatropineSodium-dependent dopamine transportertarget
DB00245BenzatropineHistamine H1 receptortarget
DB00245BenzatropineCytochrome P450 2C19enzyme
DB00245BenzatropineCytochrome P450 2D6enzyme
DB00245BenzatropineSerum albumincarrier
DB00245BenzatropineSodium-dependent serotonin transportertarget
DB00245BenzatropineSodium-dependent noradrenaline transportertarget
DB00246ZiprasidoneAlpha-1A adrenergic receptortarget
DB00246ZiprasidoneD(2) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Ctarget
DB00246ZiprasidoneD(3) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Dtarget
DB00246ZiprasidoneHistamine H1 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Atarget
DB00246ZiprasidoneD(4) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 7target
DB00246ZiprasidoneCytochrome P450 3A4enzyme
DB00246ZiprasidoneAlpha-2A adrenergic receptortarget
DB00246ZiprasidoneAlpha-1B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2C adrenergic receptortarget
DB00246ZiprasidoneD(1A) dopamine receptortarget
DB00246ZiprasidoneD(1B) dopamine receptortarget
DB00246ZiprasidoneMuscarinic acetylcholine receptor M1target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M2target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M3target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M4target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M5target
DB00246Ziprasidone5-hydroxytryptamine receptor 1Btarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Etarget
DB00246Ziprasidone5-hydroxytryptamine receptor 3Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 6target
DB00246ZiprasidoneAldehyde oxidaseenzyme
DB00248CabergolineD(2) dopamine receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 2Btarget
DB00248CabergolineD(3) dopamine receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 2Atarget
DB00248CabergolineAlpha-2B adrenergic receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 1Dtarget
DB00248CabergolineD(4) dopamine receptortarget
DB00248CabergolineAlpha-2A adrenergic receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 1Atarget
DB00248CabergolineAlpha-2C adrenergic receptortarget
DB00248CabergolineD(1B) dopamine receptortarget
DB00248CabergolineD(1A) dopamine receptortarget
DB00248Cabergoline5-hydroxytryptamine receptor 1Btarget
DB00248Cabergoline5-hydroxytryptamine receptor 2Ctarget
DB00248CabergolineCytochrome P450 3A4enzyme
DB00248Cabergoline5-hydroxytryptamine receptor 7target
DB00248CabergolineAlpha-1A adrenergic receptortarget
DB00248CabergolineAlpha-1B adrenergic receptortarget
DB00248CabergolineAlpha-1D adrenergic receptortarget
DB00248CabergolineBeta-1 adrenergic receptortarget
DB00248CabergolineBeta-2 adrenergic receptortarget
DB00248CabergolineD(1) dopamine receptortarget
DB00248CabergolineD(2S) dopamine receptortarget
DB00248CabergolineD(2L) dopamine receptortarget
DB00248CabergolineMultidrug resistance protein 1transporter
DB00252PhenytoinSodium channel protein type 5 subunit alphatarget
DB00252PhenytoinSodium channel protein type 1 subunit alphatarget
DB00252PhenytoinCytochrome P450 2C8enzyme
DB00252PhenytoinCytochrome P450 2C19enzyme
DB00252PhenytoinCytochrome P450 2C9enzyme
DB00252PhenytoinCytochrome P450 2B6enzyme
DB00252PhenytoinCytochrome P450 3A5enzyme
DB00252PhenytoinSerum albumincarrier
DB00252PhenytoinCytochrome P450 3A4enzyme
DB00252PhenytoinSolute carrier organic anion transporter family member 1C1transporter
DB00252PhenytoinMultidrug resistance protein 1transporter
DB00252PhenytoinCanalicular multispecific organic anion transporter 1transporter
DB00252PhenytoinCytochrome P450 11B1, mitochondrialenzyme
DB00252PhenytoinCytochrome P450 2C18enzyme
DB00252PhenytoinCytochrome P450 3A7enzyme
DB00252PhenytoinNuclear receptor subfamily 1 group I member 2target
DB00252PhenytoinSodium channel subunit beta-1target
DB00252PhenytoinSodium channel protein type 3 subunit alphatarget
DB00252PhenytoinUDP-glucuronosyltransferase 1-1enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-6enzyme
DB00252PhenytoinUDP-glucuronosyltransferase 1-9enzyme
DB00252PhenytoinCytochrome P450 2D6enzyme
DB00252PhenytoinThyroxine-binding globulincarrier
DB00268RopiniroleD(2) dopamine receptortarget
DB00268RopiniroleD(3) dopamine receptortarget
DB00268RopiniroleD(4) dopamine receptortarget
DB00268RopiniroleCytochrome P450 1A2enzyme
DB00268RopiniroleAlpha adrenergic receptortarget
DB00273TopiramateGamma-aminobutyric acid receptor subunit alpha-1target
DB00273TopiramateSodium channel protein type 1 subunit alphatarget
DB00273TopiramateCarbonic anhydrase 2target
DB00273TopiramateCarbonic anhydrase 4target
DB00273TopiramateGlutamate receptor ionotropic, kainate 1target
DB00273TopiramateCytochrome P450 2C19enzyme
DB00273TopiramateCytochrome P450 3A4enzyme
DB00273TopiramateGABA-A receptor (anion channel)target
DB00273TopiramateCarbonic anhydrase 1target
DB00273TopiramateCarbonic anhydrase 3target
DB00273TopiramateGlutamate receptor 1target
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineMultidrug resistance protein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C18enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00285VenlafaxineSodium-dependent serotonin transportertarget
DB00285VenlafaxineSodium-dependent noradrenaline transportertarget
DB00285VenlafaxineCytochrome P450 2D6enzyme
DB00285VenlafaxineCytochrome P450 3A4enzyme
DB00285VenlafaxineSodium-dependent dopamine transportertarget
DB00285VenlafaxineMultidrug resistance protein 1transporter
DB00285VenlafaxineATP-binding cassette sub-family G member 2transporter
DB00292EtomidateGamma-aminobutyric acid receptor subunit alpha-1target
DB00292EtomidateAlpha-2B adrenergic receptortarget
DB00292EtomidateSolute carrier family 2, facilitated glucose transporter member 1carrier
DB00292EtomidateCytochrome P450 11B1, mitochondrialenzyme
DB00292EtomidateCytochrome P450 11B2, mitochondrialenzyme
DB00292EtomidateCytochrome P450 19A1enzyme
DB00292EtomidateGABA-A receptor (anion channel)target
DB00295MorphineMu-type opioid receptortarget
DB00295MorphineDelta-type opioid receptortarget
DB00295MorphineKappa-type opioid receptortarget
DB00295MorphineCytochrome P450 2D6enzyme
DB00295MorphineMultidrug resistance protein 1transporter
DB00295MorphineCytochrome P450 2C8enzyme
DB00295MorphineCytochrome P450 3A4enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B7enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-1enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-8enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B15enzyme
DB00295MorphineUDP-glucuronosyltransferase 2B4enzyme
DB00295MorphineUDP-glucuronosyltransferase 1-3enzyme
DB00295MorphineLymphocyte antigen 96target
DB00295MorphineSerum albumincarrier
DB00296RopivacaineSodium channel protein type 10 subunit alphatarget
DB00296RopivacaineCytochrome P450 1A2enzyme
DB00296RopivacaineCytochrome P450 2B6enzyme
DB00296RopivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineSodium channel protein type 10 subunit alphatarget
DB00297BupivacaineProstaglandin E2 receptor EP1 subtypetarget
DB00297BupivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineCytochrome P450 2C19enzyme
DB00297BupivacaineCytochrome P450 2D6enzyme
DB00298DapiprazoleAlpha-1A adrenergic receptortarget
DB00298DapiprazoleAlpha-1D adrenergic receptortarget
DB00298DapiprazoleAlpha-1B adrenergic receptortarget
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00312PentobarbitalCytochrome P450 3A4enzyme
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00312PentobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00312PentobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00312PentobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00312PentobarbitalGlutamate receptor 2target
DB00312PentobarbitalGlutamate receptor ionotropic, kainate 2target
DB00312PentobarbitalCytochrome P450 2C19enzyme
DB00312PentobarbitalCytochrome P450 2A6enzyme
DB00312PentobarbitalGABA-A receptor (anion channel)target
DB00312PentobarbitalNMDA receptortarget
DB00312PentobarbitalNuclear receptor subfamily 1 group I member 2target
DB00313Valproic Acid4-aminobutyrate aminotransferase, mitochondrialtarget
DB00313Valproic AcidHistone deacetylase 9target
DB00313Valproic AcidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
DB00313Valproic AcidCytochrome P450 2A6enzyme
DB00313Valproic AcidCytochrome P450 2B6enzyme
DB00313Valproic AcidCytochrome P450 2C9enzyme
DB00313Valproic AcidSolute carrier family 22 member 5transporter
DB00313Valproic AcidSolute carrier family 22 member 6transporter
DB00313Valproic AcidSolute carrier family 22 member 8transporter
DB00313Valproic AcidMonocarboxylate transporter 1transporter
DB00313Valproic AcidSolute carrier family 22 member 7transporter
DB00313Valproic AcidCytochrome P450 3A5enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-9enzyme
DB00313Valproic AcidProstaglandin G/H synthase 1enzyme
DB00313Valproic AcidCytochrome P450 1A2enzyme
DB00313Valproic AcidCytochrome P450 2C18enzyme
DB00313Valproic AcidCytochrome P450 2C19enzyme
DB00313Valproic AcidCytochrome P450 2C8enzyme
DB00313Valproic AcidCytochrome P450 3A4enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-4enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-8enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-10enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-6enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 1-3enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 2B7enzyme
DB00313Valproic AcidUDP-glucuronosyltransferase 2B15enzyme
DB00313Valproic Acid2-oxoglutarate dehydrogenase, mitochondrialtarget
DB00313Valproic AcidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
DB00313Valproic AcidSodium channel proteintarget
DB00313Valproic AcidHistone deacetylase 2target
DB00313Valproic AcidPeroxisome proliferator-activated receptor alphatarget
DB00313Valproic AcidPeroxisome proliferator-activated receptor deltatarget
DB00313Valproic AcidPeroxisome proliferator-activated receptor gammatarget
DB00313Valproic AcidSerum albumincarrier
DB00313Valproic AcidUDP-glucuronosyltransferase 1-1enzyme
DB00313Valproic AcidSolute carrier organic anion transporter family member 2B1transporter
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenMultidrug resistance protein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin G/H synthase 3target
DB00316AcetaminophenFatty-acid amide hydrolase 1target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenGlutathione S-transferase Ptarget
DB00318CodeineMu-type opioid receptortarget
DB00318CodeineDelta-type opioid receptortarget
DB00318CodeineKappa-type opioid receptortarget
DB00318CodeineCytochrome P450 2D6enzyme
DB00318CodeineCytochrome P450 3A4enzyme
DB00318CodeineSolute carrier family 22 member 1transporter
DB00318CodeineUDP-glucuronosyltransferase 2B7enzyme
DB00318CodeineUDP-glucuronosyltransferase 2B4enzyme
DB00318CodeineMagnesium stearatecarrier
DB00318CodeineLactose monohydratecarrier
DB00318CodeineStarch, pregelatinizedcarrier
DB00318CodeineSodium starch glycolatecarrier
DB00320Dihydroergotamine5-hydroxytryptamine receptor 1Dtarget
DB00320Dihydroergotamine5-hydroxytryptamine receptor 1Btarget
DB00320DihydroergotamineCytochrome P450 3A4enzyme
DB00320DihydroergotamineAlpha-2A adrenergic receptortarget
DB00320Dihydroergotamine5-hydroxytryptamine receptor 2Btarget
DB00320DihydroergotamineMultidrug resistance protein 1transporter
DB00321AmitriptylineSodium-dependent serotonin transportertarget
DB00321AmitriptylineSodium-dependent noradrenaline transportertarget
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
DB00321AmitriptylineAlpha-2A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 1A2enzyme
DB00321AmitriptylineCytochrome P450 2C19enzyme
DB00321AmitriptylineCytochrome P450 2D6enzyme
DB00321AmitriptylineSerum albumincarrier
DB00321AmitriptylineAlpha-1-acid glycoprotein 1carrier
DB00321AmitriptylineHistamine H1 receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 2Atarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Atarget
DB00321AmitriptylineAlpha-1A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 3A4enzyme
DB00321AmitriptylineCytochrome P450 3A5enzyme
DB00321AmitriptylinePotassium voltage-gated channel subfamily A member 1target
DB00321AmitriptylineAlpha-1D adrenergic receptortarget
DB00321AmitriptylineDelta-type opioid receptortarget
DB00321AmitriptylineKappa-type opioid receptortarget
DB00321AmitriptylineHigh affinity nerve growth factor receptortarget
DB00321AmitriptylineBDNF/NT-3 growth factors receptortarget
DB00321AmitriptylineCytochrome P450 2C9enzyme
DB00321AmitriptylineCytochrome P450 2B6enzyme
DB00321AmitriptylineCytochrome P450 2C8enzyme
DB00321AmitriptylineHistamine H2 receptortarget
DB00321AmitriptylineHistamine H4 receptortarget
DB00321AmitriptylineSigma non-opioid intracellular receptor 1target
DB00321Amitriptyline5-hydroxytryptamine receptor 2Ctarget
DB00321AmitriptylineAlpha-1B adrenergic receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 7target
DB00321Amitriptyline5-hydroxytryptamine receptor 1Dtarget
DB00321AmitriptylineMu-type opioid receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Btarget
DB00321Amitriptyline5-hydroxytryptamine receptor 6target
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
DB00321AmitriptylineUDP-glucuronosyltransferase 1-1enzyme
DB00321Amitriptyline5-hydroxytryptamine receptor 1Ctarget
DB00321AmitriptylineMuscarinic acetylcholine receptortarget
DB00321AmitriptylineHERG human cardiac K+ channeltarget
DB00321AmitriptylineMultidrug resistance protein 1transporter
DB00323TolcaponeCatechol O-methyltransferasetarget
DB00323TolcaponeCytochrome P450 2C9enzyme
DB00327HydromorphoneMu-type opioid receptortarget
DB00327HydromorphoneDelta-type opioid receptortarget
DB00327HydromorphoneKappa-type opioid receptortarget
DB00327HydromorphoneCytochrome P450 3A4enzyme
DB00327HydromorphoneCytochrome P450 2C9enzyme
DB00327HydromorphoneUDP-glucuronosyltransferase 1-3enzyme
DB00327HydromorphoneUDP-glucuronosyltransferase 2B7enzyme
DB00327HydromorphoneSerum albumincarrier
DB00328IndometacinProstaglandin G/H synthase 1target
DB00328IndometacinProstaglandin G/H synthase 2target
DB00328IndometacinCytochrome P450 2C19enzyme
DB00328IndometacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndometacinPhospholipase A2, membrane associatedtarget
DB00328IndometacinProstaglandin reductase 2target
DB00328IndometacinLactoylglutathione lyasetarget
DB00328IndometacinProstaglandin D2 receptor 2target
DB00328IndometacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndometacinSerum albumincarrier
DB00328IndometacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndometacinMultidrug resistance-associated protein 4transporter
DB00328IndometacinMultidrug resistance-associated protein 6transporter
DB00328IndometacinMultidrug resistance protein 1transporter
DB00328IndometacinMultidrug resistance-associated protein 1transporter
DB00328IndometacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndometacinSolute carrier family 22 member 6transporter
DB00328IndometacinSolute carrier family 22 member 8transporter
DB00328IndometacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndometacinATP-binding cassette sub-family C member 11transporter
DB00328IndometacinSolute carrier family 22 member 11transporter
DB00328IndometacinSodium/bile acid cotransportertransporter
DB00328IndometacinSolute carrier family 22 member 7transporter
DB00328IndometacinCytochrome P450 2C9enzyme
DB00328IndometacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndometacinLiver carboxylesterase 1enzyme
DB00328IndometacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndometacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndometacinAldo-keto reductase family 1 member C3target
DB00328IndometacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndometacinBile salt export pumptransporter
DB00333MethadoneGlutamate receptor ionotropic, NMDA 3Atarget
DB00333MethadoneMu-type opioid receptortarget
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-10target
DB00333MethadoneCytochrome P450 2B6enzyme
DB00333MethadoneCytochrome P450 3A4enzyme
DB00333MethadoneCytochrome P450 2C19enzyme
DB00333MethadoneDelta-type opioid receptortarget
DB00333MethadoneCytochrome P450 3A5enzyme
DB00333MethadoneCytochrome P450 3A7enzyme
DB00333MethadoneCytochrome P450 2D6enzyme
DB00333MethadoneMultidrug resistance protein 1transporter
DB00333MethadoneCytochrome P450 2C8enzyme
DB00333MethadoneCytochrome P450 19A1enzyme
DB00333MethadoneCytochrome P450 1A2enzyme
DB00333MethadoneCytochrome P450 2C18enzyme
DB00333MethadoneCytochrome P450 2C9enzyme
DB00333Methadone5-hydroxytryptamine receptor 3Atarget
DB00333MethadoneLymphocyte antigen 96target
DB00333MethadoneAlpha-1-acid glycoprotein 2target
DB00333MethadoneThyroxine-binding globulincarrier
DB00334OlanzapineD(1A) dopamine receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineD(4) dopamine receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineD(2) dopamine receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineD(3) dopamine receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineD(1B) dopamine receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineMultidrug resistance protein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineBeta adrenergic receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 1target
DB00334OlanzapineGABA-A receptor (benzodiazepine site)target
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineUDP-glucuronosyltransferase 1-4enzyme
DB00337PimecrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
DB00337PimecrolimusSerine/threonine-protein kinase mTORtarget
DB00337PimecrolimusCytochrome P450 3A4enzyme
DB00344ProtriptylineSodium-dependent noradrenaline transportertarget
DB00344ProtriptylineSodium-dependent serotonin transportertarget
DB00344ProtriptylineCytochrome P450 2D6enzyme
DB00344ProtriptylineMultidrug resistance protein 1transporter
DB00347TrimethadioneVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00347TrimethadioneCytochrome P450 2C19enzyme
DB00347TrimethadioneCytochrome P450 2C8enzyme
DB00347TrimethadioneCytochrome P450 2C9enzyme
DB00347TrimethadioneCytochrome P450 2E1enzyme
DB00347TrimethadioneCytochrome P450 3A4enzyme
DB00349ClobazamCytochrome P450 2C19enzyme
DB00349ClobazamCytochrome P450 3A4enzyme
DB00349ClobazamCytochrome P450 2B6enzyme
DB00349ClobazamCytochrome P450 2C18enzyme
DB00349ClobazamSodium- and chloride-dependent GABA transporter 1transporter
DB00349ClobazamSodium- and chloride-dependent GABA transporter 3transporter
DB00349ClobazamMultidrug resistance protein 1transporter
DB00349ClobazamGABA-A receptor (anion channel)target
DB00349ClobazamCytochrome P450 2D6enzyme
DB00351Megestrol acetateProgesterone receptortarget
DB00351Megestrol acetateGlucocorticoid receptortarget
DB00351Megestrol acetateMultidrug resistance protein 1transporter
DB00351Megestrol acetateCytochrome P450 3A4enzyme
DB00356ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1target
DB00356ChlorzoxazoneCytochrome P450 2E1enzyme
DB00356ChlorzoxazoneCytochrome P450 1A2enzyme
DB00356ChlorzoxazoneCytochrome P450 2A6enzyme
DB00356ChlorzoxazoneCytochrome P450 1A1enzyme
DB00356ChlorzoxazoneCytochrome P450 2D6enzyme
DB00356ChlorzoxazoneCytochrome P450 3A4enzyme
DB00363ClozapineD(4) dopamine receptortarget
DB00363ClozapineHistamine H1 receptortarget
DB00363ClozapineD(2) dopamine receptortarget
DB00363ClozapineNeuron-specific vesicular protein calcyontarget
DB00363ClozapineHistamine H4 receptortarget
DB00363Clozapine5-hydroxytryptamine receptor 2Atarget
DB00363Clozapine5-hydroxytryptamine receptor 1Atarget
DB00363Clozapine5-hydroxytryptamine receptor 2Ctarget
DB00363ClozapineD(1A) dopamine receptortarget
DB00363ClozapineCytochrome P450 1A2enzyme
DB00363ClozapineCytochrome P450 2D6enzyme
DB00363ClozapineD(3) dopamine receptortarget
DB00363ClozapineMuscarinic acetylcholine receptor M1target
DB00363ClozapineMuscarinic acetylcholine receptor M2target
DB00363ClozapineMuscarinic acetylcholine receptor M3target
DB00363ClozapineMuscarinic acetylcholine receptor M4target
DB00363ClozapineMuscarinic acetylcholine receptor M5target
DB00363Clozapine5-hydroxytryptamine receptor 1Btarget
DB00363Clozapine5-hydroxytryptamine receptor 1Dtarget
DB00363Clozapine5-hydroxytryptamine receptor 1Etarget
DB00363Clozapine5-hydroxytryptamine receptor 3Atarget
DB00363Clozapine5-hydroxytryptamine receptor 6target
DB00363Clozapine5-hydroxytryptamine receptor 7target
DB00363ClozapineAlpha-1A adrenergic receptortarget
DB00363ClozapineAlpha-1B adrenergic receptortarget
DB00363ClozapineAlpha-2A adrenergic receptortarget
DB00363ClozapineAlpha-2B adrenergic receptortarget
DB00363ClozapineAlpha-2C adrenergic receptortarget
DB00363ClozapineCytochrome P450 2C9enzyme
DB00363ClozapineMultidrug resistance protein 1transporter
DB00363ClozapineCytochrome P450 3A4enzyme
DB00363ClozapineCytochrome P450 2C19enzyme
DB00363ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00363ClozapineUDP-glucuronosyltransferase 1-4enzyme
DB00363ClozapineCytochrome P450 1A1enzyme
DB00363ClozapineCytochrome P450 1B1enzyme
DB00363ClozapineCytochrome P450 2A6enzyme
DB00363ClozapineCytochrome P450 2C8enzyme
DB00363ClozapineCytochrome P450 2E1enzyme
DB00363ClozapineGlutathione S-transferase Ptarget
DB00366DoxylamineHistamine H1 receptortarget
DB00366DoxylamineMuscarinic acetylcholine receptor M1target
DB00366DoxylamineCYP2B proteinenzyme
DB00366DoxylamineNuclear receptor subfamily 1 group I member 3target
DB00370Mirtazapine5-hydroxytryptamine receptor 2Atarget
DB00370Mirtazapine5-hydroxytryptamine receptor 3Atarget
DB00370MirtazapineAlpha-2A adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Ctarget
DB00370MirtazapineKappa-type opioid receptortarget
DB00370MirtazapineHistamine H1 receptortarget
DB00370MirtazapineCytochrome P450 1A2enzyme
DB00370MirtazapineCytochrome P450 3A4enzyme
DB00370MirtazapineCytochrome P450 2D6enzyme
DB00370MirtazapineCytochrome P450 2C8enzyme
DB00370MirtazapineCytochrome P450 2C9enzyme
DB00370MirtazapineAlpha-2C adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 7target
DB00370MirtazapineAlpha-1 adrenergic receptorstarget
DB00370MirtazapineD(2) dopamine receptortarget
DB00370MirtazapineD(3) dopamine receptortarget
DB00370MirtazapineSodium-dependent noradrenaline transportertarget
DB00370MirtazapineSodium-dependent serotonin transportertarget
DB00370MirtazapineSodium-dependent dopamine transportertarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Btarget
DB00370MirtazapineD(1) dopamine receptortarget
DB00370MirtazapineHistamine H3 receptortarget
DB00370MirtazapineAlpha-1A adrenergic receptortarget
DB00370MirtazapineBeta-1 adrenergic receptortarget
DB00370MirtazapineBeta-2 adrenergic receptortarget
DB00371MeprobamateGamma-aminobutyric acid receptor subunit alpha-1target
DB00371MeprobamateGamma-aminobutyric acid receptor subunit alpha-2target
DB00371MeprobamateGamma-aminobutyric acid receptor subunit alpha-3target
DB00371MeprobamateGamma-aminobutyric acid receptor subunit alpha-4target
DB00371MeprobamateGamma-aminobutyric acid receptor subunit alpha-5target
DB00371MeprobamateGamma-aminobutyric acid receptor subunit alpha-6target
DB00371MeprobamateCytochrome P450 2C19enzyme
DB00371MeprobamateCytochrome P450 2E1enzyme
DB00371MeprobamateGABA-A receptor (anion channel)target
DB00372ThiethylperazineD(1A) dopamine receptortarget
DB00372ThiethylperazineD(4) dopamine receptortarget
DB00372ThiethylperazineD(2) dopamine receptortarget
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M1target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M2target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M3target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M4target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M5target
DB00382TacrineCytochrome P450 1A2enzyme
DB00382TacrineMultidrug resistance protein 1transporter
DB00382TacrineLiver carboxylesterase 1target
DB00387ProcyclidineMuscarinic acetylcholine receptor M1target
DB00387ProcyclidineMuscarinic acetylcholine receptor M2target
DB00387ProcyclidineMuscarinic acetylcholine receptor M4target
DB00387ProcyclidineMuscarinic acetylcholine receptor M3target
DB00391SulpirideD(2) dopamine receptortarget
DB00391SulpirideD(3) dopamine receptortarget
DB00391SulpirideCarbonic anhydrase 2target
DB00391SulpirideCarbonic anhydrase 3target
DB00395CarisoprodolCytochrome P450 2C19enzyme
DB00395CarisoprodolGamma-aminobutyric acid receptor subunit alpha-1target
DB00395CarisoprodolGamma-aminobutyric acid receptor subunit beta-2target
DB00395CarisoprodolGamma-aminobutyric acid receptor subunit gamma-2target
DB00395CarisoprodolGamma-aminobutyric acid receptor subunit alpha-5target
DB00395CarisoprodolGamma-aminobutyric acid receptor subunit alpha-3target
DB00397PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
DB00397PhenylpropanolamineD(1A) dopamine receptortarget
DB00397PhenylpropanolamineBeta-1 adrenergic receptortarget
DB00397PhenylpropanolamineBeta-2 adrenergic receptortarget
DB00397PhenylpropanolamineAlpha-2 adrenergic receptorstarget
DB00402EszopicloneTranslocator proteintarget
DB00402EszopicloneCytochrome P450 3A4enzyme
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-1target
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-2target
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-3target
DB00402EszopicloneGamma-aminobutyric acid receptor subunit alpha-5target
DB00402EszopicloneCytochrome P450 2C9enzyme
DB00402EszopicloneCytochrome P450 2C8enzyme
DB00402EszopicloneProstaglandin G/H synthase 1enzyme
DB00402EszopicloneGABA-A receptor (anion channel)target
DB00404AlprazolamCytochrome P450 3A4enzyme
DB00404AlprazolamCytochrome P450 2C9enzyme
DB00404AlprazolamCytochrome P450 3A5enzyme
DB00404AlprazolamCytochrome P450 3A7enzyme
DB00404AlprazolamGABA-A receptor (anion channel)target
DB00408LoxapineD(1A) dopamine receptortarget
DB00408LoxapineD(2) dopamine receptortarget
DB00408Loxapine5-hydroxytryptamine receptor 2Atarget
DB00408Loxapine5-hydroxytryptamine receptor 2Ctarget
DB00408Loxapine5-hydroxytryptamine receptor 1Atarget
DB00408Loxapine5-hydroxytryptamine receptor 1Btarget
DB00408Loxapine5-hydroxytryptamine receptor 1Dtarget
DB00408Loxapine5-hydroxytryptamine receptor 1Etarget
DB00408Loxapine5-hydroxytryptamine receptor 3Atarget
DB00408Loxapine5-hydroxytryptamine receptor 5Atarget
DB00408Loxapine5-hydroxytryptamine receptor 6target
DB00408Loxapine5-hydroxytryptamine receptor 7target
DB00408LoxapineAlpha-1A adrenergic receptortarget
DB00408LoxapineAlpha-1B adrenergic receptortarget
DB00408LoxapineAlpha-2A adrenergic receptortarget
DB00408LoxapineAlpha-2B adrenergic receptortarget
DB00408LoxapineAlpha-2C adrenergic receptortarget
DB00408LoxapineBeta-1 adrenergic receptortarget
DB00408LoxapineMuscarinic acetylcholine receptor M1target
DB00408LoxapineMuscarinic acetylcholine receptor M2target
DB00408LoxapineMuscarinic acetylcholine receptor M3target
DB00408LoxapineMuscarinic acetylcholine receptor M4target
DB00408LoxapineMuscarinic acetylcholine receptor M5target
DB00408LoxapineD(1) dopamine receptortarget
DB00408LoxapineD(3) dopamine receptortarget
DB00408LoxapineD(4) dopamine receptortarget
DB00408LoxapineD(1B) dopamine receptortarget
DB00408LoxapineHistamine H1 receptortarget
DB00408LoxapineHistamine H2 receptortarget
DB00408LoxapineHistamine H4 receptortarget
DB00408LoxapineSodium-dependent serotonin transportertarget
DB00408LoxapineSodium-dependent noradrenaline transportertarget
DB00408LoxapineSodium-dependent dopamine transportertarget
DB00409RemoxiprideD(2) dopamine receptortarget
DB00409RemoxiprideD(4) dopamine receptortarget
DB00409Remoxipride5-hydroxytryptamine receptor 2Atarget
DB00409RemoxiprideSigma non-opioid intracellular receptor 1target
DB00409RemoxiprideD(3) dopamine receptortarget
DB00409RemoxiprideCytochrome P450 2D6enzyme
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M1target
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M2target
DB00411CarbamoylcholineNeuronal acetylcholine receptor subunit alpha-2target
DB00411CarbamoylcholineCytosolic phospholipase A2enzyme
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M3target
DB00411CarbamoylcholineMuscarinic acetylcholine receptor M4target
DB00413PramipexoleD(3) dopamine receptortarget
DB00413PramipexoleD(4) dopamine receptortarget
DB00413PramipexoleD(2) dopamine receptortarget
DB00413Pramipexole5-hydroxytryptamine receptor 1Atarget
DB00413PramipexoleAlpha-2A adrenergic receptortarget
DB00413PramipexoleSolute carrier family 22 member 2transporter
DB00413PramipexoleSolute carrier family 22 member 1transporter
DB00413PramipexoleSolute carrier family 22 member 3transporter
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00418SecobarbitalCytochrome P450 2C8enzyme
DB00418SecobarbitalCytochrome P450 2C9enzyme
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00418SecobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00418SecobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00418SecobarbitalGlutamate receptor 2target
DB00418SecobarbitalGlutamate receptor ionotropic, kainate 2target
DB00418SecobarbitalCytochrome P450 1A2enzyme
DB00418SecobarbitalNMDA receptortarget
DB00418SecobarbitalCytochrome P450 2C19enzyme
DB00420PromazineD(2) dopamine receptortarget
DB00420PromazineMuscarinic acetylcholine receptor M4target
DB00420PromazineMuscarinic acetylcholine receptor M2target
DB00420PromazineMuscarinic acetylcholine receptor M3target
DB00420PromazineAlpha-1B adrenergic receptortarget
DB00420PromazineD(1A) dopamine receptortarget
DB00420PromazineMuscarinic acetylcholine receptor M5target
DB00420Promazine5-hydroxytryptamine receptor 2Atarget
DB00420Promazine5-hydroxytryptamine receptor 2Ctarget
DB00420PromazineAlpha-1A adrenergic receptortarget
DB00420PromazineMuscarinic acetylcholine receptor M1target
DB00420PromazineD(4) dopamine receptortarget
DB00420PromazineHistamine H1 receptortarget
DB00420PromazineAlpha-1D adrenergic receptortarget
DB00420PromazineCytochrome P450 2C19enzyme
DB00420PromazineCytochrome P450 1A2enzyme
DB00420PromazineCytochrome P450 3A4enzyme
DB00420PromazineCytochrome P450 2C9enzyme
DB00420PromazineCytochrome P450 2D6enzyme
DB00422MethylphenidateSodium-dependent dopamine transportertarget
DB00422MethylphenidateSodium-dependent noradrenaline transportertarget
DB00422Methylphenidate5-hydroxytryptamine receptor 1Atarget
DB00423MethocarbamolCarbonic anhydrase 1target
DB00424HyoscyamineMuscarinic acetylcholine receptor M1target
DB00424HyoscyamineMuscarinic acetylcholine receptor M2target
DB00424HyoscyamineMuscarinic acetylcholine receptor M3target
DB00424HyoscyamineMuscarinic acetylcholine receptor M4target
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-1target
DB00425ZolpidemCytochrome P450 3A4enzyme
DB00425ZolpidemCytochrome P450 1A2enzyme
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-2target
DB00425ZolpidemGamma-aminobutyric acid receptor subunit alpha-3target
DB00425ZolpidemCytochrome P450 2C9enzyme
DB00425ZolpidemCytochrome P450 2C19enzyme
DB00425ZolpidemCytochrome P450 2D6enzyme
DB00425ZolpidemGamma-aminobutyric acid receptor subunit gamma-2target
DB00433ProchlorperazineD(2) dopamine receptortarget
DB00433ProchlorperazineCytochrome P450 2D6enzyme
DB00433ProchlorperazineCytochrome P450 3A4enzyme
DB00450DroperidolD(2) dopamine receptortarget
DB00450DroperidolAlpha-1A adrenergic receptortarget
DB00454MeperidineKappa-type opioid receptortarget
DB00454MeperidineCytochrome P450 2D6enzyme
DB00454MeperidineCytochrome P450 2B6enzyme
DB00454MeperidineGlutamate receptor ionotropic, NMDA 1target
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Btarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Atarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Ctarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Dtarget
DB00454MeperidineCytochrome P450 2C19enzyme
DB00454MeperidineCytochrome P450 3A4enzyme
DB00454MeperidineSerum albumincarrier
DB00454MeperidineAlpha-1-acid glycoprotein 1carrier
DB00454MeperidineMuscarinic acetylcholine receptortarget
DB00454MeperidineMu-type opioid receptortarget
DB00454MeperidineSodium-dependent dopamine transportertarget
DB00454MeperidineSodium-dependent noradrenaline transportertarget
DB00454MeperidineSodium-dependent serotonin transportertarget
DB00454MeperidineLiver carboxylesterase 1target
DB00454MeperidineCytochrome P450 1A2enzyme
DB00458ImipramineSodium-dependent noradrenaline transportertarget
DB00458ImipramineSodium-dependent serotonin transportertarget
DB00458ImipramineCytochrome P450 1A2enzyme
DB00458ImipramineCytochrome P450 2C19enzyme
DB00458ImipramineCytochrome P450 2D6enzyme
DB00458ImipramineHistamine H1 receptortarget
DB00458ImipramineAlpha-1A adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 2Atarget
DB00458ImipramineMuscarinic acetylcholine receptor M1target
DB00458ImipramineMuscarinic acetylcholine receptor M2target
DB00458ImipramineMuscarinic acetylcholine receptor M3target
DB00458ImipramineMuscarinic acetylcholine receptor M4target
DB00458ImipramineMuscarinic acetylcholine receptor M5target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 2target
DB00458ImipraminePotassium voltage-gated channel subfamily D member 3target
DB00458ImipramineAlpha-1D adrenergic receptortarget
DB00458ImipramineAlpha-1-acid glycoprotein 1carrier
DB00458ImipramineSolute carrier family 22 member 2transporter
DB00458ImipramineSolute carrier family 22 member 3transporter
DB00458ImipramineMultidrug resistance protein 1transporter
DB00458ImipramineSolute carrier family 22 member 4transporter
DB00458ImipramineCytochrome P450 3A4enzyme
DB00458ImipramineCytochrome P450 2B6enzyme
DB00458ImipramineCytochrome P450 2C18enzyme
DB00458ImipramineCytochrome P450 2E1enzyme
DB00458ImipramineCytochrome P450 3A7enzyme
DB00458Imipramine5-hydroxytryptamine receptor 2Ctarget
DB00458ImipramineAlpha-1B adrenergic receptortarget
DB00458Imipramine5-hydroxytryptamine receptor 7target
DB00458ImipramineD(1) dopamine receptortarget
DB00458ImipramineD(2) dopamine receptortarget
DB00458ImipraminePotassium voltage-gated channel subfamily H member 2target
DB00458ImipramineSodium-dependent dopamine transportertarget
DB00458Imipramine5-hydroxytryptamine receptor 1Atarget
DB00458Imipramine5-hydroxytryptamine receptor 6target
DB00458ImipraminePotassium voltage-gated channel subfamily H member 1target
DB00458ImipramineSerum albumincarrier
DB00458ImipramineAlpha-1-acid glycoprotein 2target
DB00461NabumetoneProstaglandin G/H synthase 1target
DB00461NabumetoneProstaglandin G/H synthase 2target
DB00461NabumetoneCytochrome P450 1A2enzyme
DB00466PicrotoxinGamma-aminobutyric acid receptor subunit rho-1target
DB00466PicrotoxinGamma-aminobutyric acid receptor subunit alpha-1target
DB00466PicrotoxinGlycine receptor subunit alpha-2target
DB00466PicrotoxinGlycine receptor subunit alpha-3target
DB00466PicrotoxinCytochrome P450 1A1enzyme
DB00466PicrotoxinGlutamine synthetaseenzyme
DB00466PicrotoxinGlycine receptor subunit alpha-1target
DB00468QuininePlatelet glycoprotein IXtarget
DB00468QuinineIntermediate conductance calcium-activated potassium channel protein 4target
DB00468QuinineCytochrome P450 3A4enzyme
DB00468QuinineCytochrome P450 3A5enzyme
DB00468QuinineCytochrome P450 1A1enzyme
DB00468QuinineCytochrome P450 2D6enzyme
DB00468QuinineCytochrome P450 1A2enzyme
DB00468QuinineCytochrome P450 2C8enzyme
DB00468QuinineCytochrome P450 2C9enzyme
DB00468QuinineCytochrome P450 2C19enzyme
DB00468QuinineCytochrome P450 2E1enzyme
DB00468QuinineCytochrome P450 3A7enzyme
DB00468QuinineSolute carrier family 22 member 2transporter
DB00468QuinineSolute carrier family 22 member 1transporter
DB00468QuinineSolute carrier family 22 member 5transporter
DB00468QuinineMultidrug resistance protein 1transporter
DB00468QuinineSolute carrier organic anion transporter family member 1A2transporter
DB00468QuinineSolute carrier family 22 member 4transporter
DB00468QuinineFe(II)-protoporphyrin IXtarget
DB00468QuinineSolute carrier organic anion transporter family member 1B1transporter
DB00469TenoxicamProstaglandin G/H synthase 1target
DB00469TenoxicamProstaglandin G/H synthase 2target
DB00469TenoxicamCytochrome P450 2C9enzyme
DB00469TenoxicamSolute carrier family 22 member 8transporter
DB00470DronabinolCannabinoid receptor 1target
DB00470DronabinolCytochrome P450 3A4enzyme
DB00470DronabinolCytochrome P450 2C9enzyme
DB00470DronabinolCannabinoid receptor 2target
DB00470DronabinolMultidrug resistance protein 1transporter
DB00470DronabinolATP-binding cassette sub-family G member 2transporter
DB00470DronabinolCytochrome P450 2C19enzyme
DB00470DronabinolProstaglandin G/H synthase 1enzyme
DB00470DronabinolCytochrome P450 1A1enzyme
DB00470DronabinolCytochrome P450 2A6enzyme
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineMultidrug resistance protein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target
DB00474MethohexitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00474MethohexitalCytochrome P450 2C19enzyme
DB00475ChlordiazepoxideCytochrome P450 3A4enzyme
DB00475ChlordiazepoxideGABA-A receptor (anion channel)target
DB00476DuloxetineSodium-dependent serotonin transportertarget
DB00476DuloxetineSodium-dependent dopamine transportertarget
DB00476DuloxetineSodium-dependent noradrenaline transportertarget
DB00476DuloxetineCytochrome P450 1A2enzyme
DB00476DuloxetineCytochrome P450 2D6enzyme
DB00476DuloxetineCytochrome P450 3A4enzyme
DB00477ChlorpromazineD(2) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Atarget
DB00477ChlorpromazineCytochrome P450 2D6enzyme
DB00477ChlorpromazineCytochrome P450 1A2enzyme
DB00477ChlorpromazineSerum albumincarrier
DB00477ChlorpromazineMultidrug resistance protein 1transporter
DB00477ChlorpromazineD(1A) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 1Atarget
DB00477ChlorpromazineAlpha-1A adrenergic receptortarget
DB00477ChlorpromazineAlpha-1B adrenergic receptortarget
DB00477ChlorpromazineCytochrome P450 2E1enzyme
DB00477ChlorpromazineCytochrome P450 3A4enzyme
DB00477ChlorpromazineHistamine H1 receptortarget
DB00477ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
DB00477ChlorpromazineD(1) dopamine receptortarget
DB00477ChlorpromazineD(3) dopamine receptortarget
DB00477ChlorpromazineD(4) dopamine receptortarget
DB00477ChlorpromazineD(1B) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
DB00477Chlorpromazine5-hydroxytryptamine 2 receptortarget
DB00477ChlorpromazineAlpha-1 adrenergic receptorstarget
DB00477ChlorpromazineAlpha-2 adrenergic receptorstarget
DB00477ChlorpromazineMuscarinic acetylcholine receptor M1target
DB00477ChlorpromazineMuscarinic acetylcholine receptor M3target
DB00477ChlorpromazineSphingomyelin phosphodiesterasetarget
DB00477Chlorpromazinealpha1-acid glycoproteintarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 6target
DB00477Chlorpromazine5-hydroxytryptamine receptor 7target
DB00477ChlorpromazineHistamine H4 receptortarget
DB00477ChlorpromazineBile salt export pumptransporter
DB00482CelecoxibProstaglandin G/H synthase 2target
DB00482Celecoxib3-phosphoinositide-dependent protein kinase 1target
DB00482CelecoxibCytochrome P450 2C9enzyme
DB00482CelecoxibCytochrome P450 2D6enzyme
DB00482CelecoxibMultidrug resistance-associated protein 4transporter
DB00482CelecoxibCytochrome P450 3A4enzyme
DB00482CelecoxibCytochrome P450 2C8enzyme
DB00482CelecoxibCarbonic anhydrase 2target
DB00482CelecoxibCarbonic anhydrase 3target
DB00482CelecoxibATP-binding cassette sub-family B member 5target
DB00482CelecoxibATP-binding cassette sub-family G member 2target
DB00482CelecoxibMultidrug resistance protein 1target
DB00482CelecoxibBile salt export pumptransporter
DB00486NabiloneCannabinoid receptor 2target
DB00486NabiloneCannabinoid receptor 1target
DB00486NabiloneCytochrome P450 2E1enzyme
DB00486NabiloneCytochrome P450 2C8enzyme
DB00486NabiloneCytochrome P450 2C9enzyme
DB00490Buspirone5-hydroxytryptamine receptor 1Atarget
DB00490BuspironeD(2) dopamine receptortarget
DB00490BuspironeCytochrome P450 3A4enzyme
DB00490BuspironeCytochrome P450 3A5enzyme
DB00490BuspironeCytochrome P450 3A7enzyme
DB00490BuspironeMultidrug resistance protein 1transporter
DB00490BuspironeCytochrome P450 2D6enzyme
DB00494EntacaponeCatechol O-methyltransferasetarget
DB00494EntacaponeCatechol O-methyltransferaseenzyme
DB00494EntacaponeUDP-glucuronosyltransferase 1-9enzyme
DB00494EntacaponeCytochrome P450 2D6enzyme
DB00497OxycodoneMu-type opioid receptortarget
DB00497OxycodoneKappa-type opioid receptortarget
DB00497OxycodoneDelta-type opioid receptortarget
DB00497OxycodoneCytochrome P450 2D6enzyme
DB00497OxycodoneCytochrome P450 3A4enzyme
DB00497OxycodoneCytochrome P450 3A5enzyme
DB00497OxycodoneKappa-type opioid receptor 2btarget
DB00497Oxycodonealpha1-acid glycoproteintarget
DB00500TolmetinProstaglandin G/H synthase 1target
DB00500TolmetinProstaglandin G/H synthase 2target
DB00500TolmetinSolute carrier family 22 member 6transporter
DB00500TolmetinTryptophan 2,3-dioxygenaseenzyme
DB00500TolmetinSerum albumincarrier
DB00502HaloperidolD(2) dopamine receptortarget
DB00502HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
DB00502HaloperidolD(1A) dopamine receptortarget
DB00502HaloperidolCytochrome P450 1A2enzyme
DB00502HaloperidolCytochrome P450 2D6enzyme
DB00502Haloperidol5-hydroxytryptamine receptor 2Atarget
DB00502HaloperidolD(3) dopamine receptortarget
DB00502HaloperidolCytochrome P450 3A4enzyme
DB00502HaloperidolCytochrome P450 3A5enzyme
DB00502HaloperidolCytochrome P450 3A7enzyme
DB00502HaloperidolMultidrug resistance protein 1transporter
DB00502HaloperidolCarbonyl reductase [NADPH] 1enzyme
DB00502HaloperidolUDP-glucuronosyltransferase 1-9enzyme
DB00502HaloperidolCytochrome P450 1A1enzyme
DB00502HaloperidolCytochrome P450 2C19enzyme
DB00502HaloperidolCytochrome P450 2C9enzyme
DB00502HaloperidolMelanin-concentrating hormone receptor 1target
DB00502HaloperidolSynaptic vesicular amine transportertarget
DB00504LevallorphanMu-type opioid receptortarget
DB00508TriflupromazineD(1A) dopamine receptortarget
DB00508TriflupromazineD(2) dopamine receptortarget
DB00508TriflupromazineMuscarinic acetylcholine receptor M1target
DB00508TriflupromazineMuscarinic acetylcholine receptor M2target
DB00508Triflupromazine5-hydroxytryptamine receptor 2Btarget
DB00508TriflupromazineMultidrug resistance protein 1transporter
DB00514DextromethorphanSigma non-opioid intracellular receptor 1target
DB00514DextromethorphanHCG20471, isoform CRA_ctarget
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DB00514DextromethorphanSodium-dependent serotonin transportertarget
DB00514DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DB00514DextromethorphanCytochrome P450 2D6enzyme
DB00514DextromethorphanCytochrome P450 3A4enzyme
DB00514DextromethorphanCytochrome P450 3A5enzyme
DB00514DextromethorphanCytochrome P450 3A7enzyme
DB00514DextromethorphanCytochrome P450 2C9enzyme
DB00514DextromethorphanCytochrome P450 2B6enzyme
DB00514DextromethorphanCytochrome P450 2C19enzyme
DB00514DextromethorphanCytochrome P450 2C8enzyme
DB00514DextromethorphanCytochrome P450 2E1enzyme
DB00514DextromethorphanMembrane-associated progesterone receptor component 1target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DB00514DextromethorphanMu-type opioid receptortarget
DB00514DextromethorphanDelta-type opioid receptortarget
DB00514DextromethorphanKappa-type opioid receptortarget
DB00514DextromethorphanNADPH oxidasetarget
DB00514DextromethorphanSodium-dependent noradrenaline transportertarget
DB00527CinchocaineSodium channel protein type 5 subunit alphatarget
DB00527CinchocaineSodium channel protein type 10 subunit alphatarget
DB00532MephenytoinSodium channel protein type 5 subunit alphatarget
DB00532MephenytoinCytochrome P450 2B6enzyme
DB00532MephenytoinCytochrome P450 2C9enzyme
DB00532MephenytoinCytochrome P450 2C19enzyme
DB00532MephenytoinCytochrome P450 1A2enzyme
DB00532MephenytoinCytochrome P450 2D6enzyme
DB00532MephenytoinCytochrome P450 2C8enzyme
DB00532MephenytoinNuclear receptor subfamily 1 group I member 2target
DB00532MephenytoinThyroxine-binding globulincarrier
DB00533RofecoxibProstaglandin G/H synthase 2target
DB00533RofecoxibCytochrome P450 3A4enzyme
DB00533RofecoxibCytochrome P450 1A2enzyme
DB00533RofecoxibMultidrug resistance-associated protein 4transporter
DB00533RofecoxibProstaglandin G/H synthase 1enzyme
DB00533RofecoxibCytochrome P450 2C8enzyme
DB00533RofecoxibCytochrome P450 2C9enzyme
DB00540NortriptylineSodium-dependent serotonin transportertarget
DB00540NortriptylineSodium-dependent noradrenaline transportertarget
DB00540NortriptylineCytochrome P450 1A2enzyme
DB00540NortriptylineCytochrome P450 2D6enzyme
DB00540NortriptylineSerum albumincarrier
DB00540NortriptylineAlpha-1-acid glycoprotein 1carrier
DB00540NortriptylineHistamine H1 receptortarget
DB00540NortriptylineMuscarinic acetylcholine receptor M1target
DB00540NortriptylineMuscarinic acetylcholine receptor M2target
DB00540NortriptylineMuscarinic acetylcholine receptor M3target
DB00540NortriptylineMuscarinic acetylcholine receptor M4target
DB00540NortriptylineMuscarinic acetylcholine receptor M5target
DB00540Nortriptyline5-hydroxytryptamine receptor 2Atarget
DB00540NortriptylineAlpha-1A adrenergic receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Atarget
DB00540NortriptylineCytochrome P450 3A4enzyme
DB00540NortriptylineCytochrome P450 3A5enzyme
DB00540NortriptylineAlpha-1D adrenergic receptortarget
DB00540NortriptylineCytochrome P450 2C19enzyme
DB00540NortriptylineProstaglandin G/H synthase 1enzyme
DB00540NortriptylineCytochrome P450 2E1enzyme
DB00540Nortriptyline5-hydroxytryptamine receptor 2Ctarget
DB00540Nortriptyline5-hydroxytryptamine receptor 6target
DB00540NortriptylineAlpha-1B adrenergic receptortarget
DB00540NortriptylineAlpha-2 adrenergic receptorstarget
DB00540NortriptylineBeta adrenergic receptortarget
DB00540NortriptylineD(2) dopamine receptortarget
DB00540NortriptylineSigma receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Ctarget
DB00543AmoxapineSodium-dependent serotonin transportertarget
DB00543AmoxapineSodium-dependent noradrenaline transportertarget
DB00543AmoxapineAlpha-2A adrenergic receptortarget
DB00543AmoxapineD(2) dopamine receptortarget
DB00543AmoxapineAlpha-1A adrenergic receptortarget
DB00543AmoxapineD(1A) dopamine receptortarget
DB00543AmoxapineMuscarinic acetylcholine receptor M1target
DB00543AmoxapineGamma-aminobutyric acid receptor subunit alpha-1target
DB00543AmoxapineAlpha-1-acid glycoprotein 1carrier
DB00543AmoxapineCytochrome P450 2D6enzyme
DB00543Amoxapine5-hydroxytryptamine receptor 2Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Ctarget
DB00543Amoxapine5-hydroxytryptamine receptor 6target
DB00543Amoxapine5-hydroxytryptamine receptor 7target
DB00543AmoxapineD(3) dopamine receptortarget
DB00543AmoxapineD(4) dopamine receptortarget
DB00543AmoxapineHistamine H1 receptortarget
DB00543AmoxapineAlpha-1 adrenergic receptorstarget
DB00543AmoxapineMuscarinic acetylcholine receptortarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Btarget
DB00543Amoxapine5-hydroxytryptamine receptor 3Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Btarget
DB00543AmoxapineAlpha-2 adrenergic receptorstarget
DB00543AmoxapineHistamine H4 receptortarget
DB00543AmoxapineGABA-A receptor (anion channel)target
DB00543AmoxapineSodium-dependent dopamine transportertarget
DB00546AdinazolamCytochrome P450 2C19enzyme
DB00546AdinazolamCytochrome P450 3A4enzyme
DB00546AdinazolamGamma-aminobutyric acid receptor subunit alpha-1target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit alpha-2target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit alpha-3target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit alpha-5target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit gamma-1target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit gamma-2target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit gamma-3target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit beta-1target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit beta-2target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit beta-3target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit deltatarget
DB00546AdinazolamGamma-aminobutyric acid receptor subunit epsilontarget
DB00546AdinazolamGamma-aminobutyric acid receptor subunit pitarget
DB00546AdinazolamGamma-aminobutyric acid receptor subunit rho-1target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit rho-2target
DB00546AdinazolamGamma-aminobutyric acid receptor subunit rho-3target
DB00554PiroxicamProstaglandin G/H synthase 1target
DB00554PiroxicamProstaglandin G/H synthase 2target
DB00554PiroxicamSerum albumincarrier
DB00554PiroxicamCytochrome P450 2C9enzyme
DB00554PiroxicamSolute carrier family 22 member 6transporter
DB00554PiroxicamSolute carrier family 22 member 8transporter
DB00554PiroxicamSolute carrier family 22 member 11transporter
DB00554PiroxicamCytochrome P450 2C8enzyme
DB00554PiroxicamSolute carrier organic anion transporter family member 2B1transporter
DB00555LamotrigineSodium channel protein type 2 subunit alphatarget
DB00555LamotrigineUDP-glucuronosyltransferase 1-4enzyme
DB00555LamotrigineMultidrug resistance protein 1transporter
DB00555LamotrigineUDP-glucuronosyltransferase 1-3enzyme
DB00555LamotrigineDihydrofolate reductaseenzyme
DB00555Lamotrigine5-hydroxytryptamine receptor 3Atarget
DB00555LamotrigineVoltage-dependent R-type calcium channel subunit alpha-1Etarget
DB00555LamotrigineAdenosine receptor A1target
DB00555LamotrigineAdenosine receptor A2atarget
DB00555LamotrigineAlpha-1A adrenergic receptortarget
DB00555LamotrigineAlpha-2A adrenergic receptortarget
DB00555LamotrigineBeta-1 adrenergic receptortarget
DB00555LamotrigineD(1) dopamine receptortarget
DB00555LamotrigineD(2) dopamine receptortarget
DB00555LamotrigineGABA-A receptor (anion channel)target
DB00555LamotrigineGABA-A receptor (benzodiazepine site)target
DB00555LamotrigineHistamine H1 receptortarget
DB00555LamotrigineKappa-type opioid receptortarget
DB00555LamotrigineMuscarinic acetylcholine receptortarget
DB00555Lamotrigine5-hydroxytryptamine receptor 2Atarget
DB00555LamotrigineUDP-glucuronosyltransferase 1-1enzyme
DB00555LamotrigineSolute carrier family 22 member 2transporter
DB00561DoxapramPotassium channel subfamily K member 3target
DB00561DoxapramPotassium channel subfamily K member 9target
DB00564CarbamazepineSodium channel protein type 5 subunit alphatarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineMultidrug resistance protein 1transporter
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineCytochrome P450 3A7enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNeuronal acetylcholine receptor subunit beta-2target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineThyroxine-binding globulincarrier
DB00572AtropineMuscarinic acetylcholine receptor M2target
DB00572AtropineMuscarinic acetylcholine receptor M1target
DB00572AtropineMuscarinic acetylcholine receptor M4target
DB00572AtropineMuscarinic acetylcholine receptor M5target
DB00572AtropineMuscarinic acetylcholine receptor M3target
DB00572AtropineGlycine receptor subunit alpha-1target
DB00572AtropineNeuronal acetylcholine receptor subunit alpha-4target
DB00572AtropineNeuronal acetylcholine receptor subunit beta-2target
DB00572AtropineBile salt export pumptransporter
DB00573FenoprofenProstaglandin G/H synthase 1target
DB00573FenoprofenProstaglandin G/H synthase 2target
DB00573FenoprofenSerum albumincarrier
DB00573FenoprofenPeroxisome proliferator-activated receptor alphatarget
DB00573FenoprofenPeroxisome proliferator-activated receptor gammatarget
DB00575ClonidineAlpha-2A adrenergic receptortarget
DB00575ClonidineCytochrome P450 2D6enzyme
DB00575ClonidineAlpha-2B adrenergic receptortarget
DB00575ClonidineAlpha-2C adrenergic receptortarget
DB00575ClonidineSolute carrier family 22 member 3transporter
DB00575ClonidineSolute carrier family 22 member 5transporter
DB00575ClonidineSolute carrier family 22 member 4transporter
DB00575ClonidineMultidrug resistance protein 1transporter
DB00575ClonidineCytochrome P450 1A2enzyme
DB00575ClonidineCytochrome P450 3A4enzyme
DB00575ClonidineCytochrome P450 1A1enzyme
DB00575ClonidineCytochrome P450 3A5enzyme
DB00575ClonidineAlpha-1A adrenergic receptortarget
DB00575ClonidineAlpha-1B adrenergic receptortarget
DB00575ClonidineAlpha-1D adrenergic receptortarget
DB00579MazindolSodium-dependent noradrenaline transportertarget
DB00579MazindolSodium-dependent dopamine transportertarget
DB00579MazindolSodium-dependent serotonin transportertarget
DB00579MazindolSynaptic vesicular amine transportertarget
DB00580ValdecoxibProstaglandin G/H synthase 2target
DB00580ValdecoxibCytochrome P450 2C9enzyme
DB00580ValdecoxibCytochrome P450 3A4enzyme
DB00580ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
DB00580ValdecoxibCarbonic anhydrase 2target
DB00580ValdecoxibCarbonic anhydrase 3target
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-1enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance protein 1transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacProstaglandin G/H synthase 1enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 1A1enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacArachidonate 5-lipoxygenasetarget
DB00586DiclofenacSodium channel protein type 4 subunit alphatarget
DB00586DiclofenacAcid-sensing ion channel 1target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3target
DB00586DiclofenacPhospholipase A2, membrane associatedtarget
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00589LisurideD(1A) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Atarget
DB00589LisurideD(2) dopamine receptortarget
DB00589LisurideAlpha-2A adrenergic receptortarget
DB00589LisurideAlpha-2B adrenergic receptortarget
DB00589LisurideAlpha-2C adrenergic receptortarget
DB00589LisurideD(3) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Dtarget
DB00589Lisuride5-hydroxytryptamine receptor 2Btarget
DB00589Lisuride5-hydroxytryptamine receptor 2Atarget
DB00589LisurideD(4) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 2Ctarget
DB00589LisurideD(1B) dopamine receptortarget
DB00589Lisuride5-hydroxytryptamine receptor 1Btarget
DB00589LisurideCytochrome P450 2D6enzyme
DB00589LisurideCytochrome P450 3A4enzyme
DB00589Lisuride5-hydroxytryptamine receptor 7target
DB00593EthosuximideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00593EthosuximideCytochrome P450 3A4enzyme
DB00593EthosuximideCytochrome P450 2E1enzyme
DB00593EthosuximideCytochrome P450 3A43enzyme
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-1target
DB00599ThiopentalFatty-acid amide hydrolase 1target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-2target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-3target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-4target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-5target
DB00599ThiopentalGamma-aminobutyric acid receptor subunit alpha-6target
DB00599ThiopentalNeuronal acetylcholine receptor subunit alpha-4target
DB00599ThiopentalNeuronal acetylcholine receptor subunit alpha-7target
DB00599ThiopentalGlutamate receptor 2target
DB00599ThiopentalGlutamate receptor ionotropic, kainate 2target
DB00599ThiopentalCytochrome P450 2E1enzyme
DB00599ThiopentalCytochrome P450 3A4enzyme
DB00599ThiopentalMuscarinic acetylcholine receptor M3target
DB00599ThiopentalCytochrome P450 2C19enzyme
DB00605SulindacProstaglandin G/H synthase 2target
DB00605SulindacAldose reductasetarget
DB00605SulindacProstaglandin G/H synthase 1target
DB00605SulindacMitogen-activated protein kinase 3target
DB00605SulindacPeroxisome proliferator-activated receptor deltatarget
DB00605SulindacProstaglandin D2 receptor 2target
DB00605SulindacSerum albumincarrier
DB00605SulindacSolute carrier family 22 member 6transporter
DB00605SulindacCytochrome P450 1A1enzyme
DB00605SulindacAldo-keto reductase family 1 member B10target
DB00608ChloroquineTumor necrosis factortarget
DB00608ChloroquineToll-like receptor 9target
DB00608ChloroquineGlutathione S-transferase A2target
DB00608ChloroquineCytochrome P450 2D6enzyme
DB00608ChloroquineCytochrome P450 3A4enzyme
DB00608ChloroquineCytochrome P450 1A1enzyme
DB00608ChloroquineCytochrome P450 2C8enzyme
DB00608ChloroquineCytochrome P450 3A5enzyme
DB00608ChloroquineFe(II)-protoporphyrin IXtarget
DB00608ChloroquineGlutathione S-transferasetarget
DB00608ChloroquineMultidrug resistance protein 1transporter
DB00611ButorphanolKappa-type opioid receptortarget
DB00611ButorphanolMu-type opioid receptortarget
DB00611ButorphanolDelta-type opioid receptortarget
DB00623FluphenazineD(2) dopamine receptortarget
DB00623FluphenazineD(1A) dopamine receptortarget
DB00623FluphenazineCytochrome P450 2D6enzyme
DB00623FluphenazineMultidrug resistance protein 1transporter
DB00623FluphenazineCytochrome P450 2E1enzyme
DB00623FluphenazineAndrogen receptortarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Atarget
DB00623Fluphenazine5-hydroxytryptamine receptor 2Ctarget
DB00628Clorazepic acidTranslocator proteintarget
DB00628Clorazepic acidCytochrome P450 3A4enzyme
DB00628Clorazepic acidGABA-A receptor (anion channel)target
DB00633DexmedetomidineAlpha-2A adrenergic receptortarget
DB00633DexmedetomidineCytochrome P450 2E1enzyme
DB00633DexmedetomidineCytochrome P450 1A2enzyme
DB00633DexmedetomidineCytochrome P450 1A1enzyme
DB00633DexmedetomidineCytochrome P450 2D6enzyme
DB00640AdenosineAdenosine receptor A3target
DB00640AdenosineAdenosine deaminaseenzyme
DB00640AdenosineAdenosine kinaseenzyme
DB00640AdenosineAdenosine receptor A1target
DB00640AdenosineAdenosine receptor A2atarget
DB00640AdenosineAdenosine receptor A2btarget
DB00640AdenosineSolute carrier family 28 member 3transporter
DB00645DyclonineSodium channel protein type 10 subunit alphatarget
DB00647DextropropoxypheneMu-type opioid receptortarget
DB00647DextropropoxypheneDelta-type opioid receptortarget
DB00647DextropropoxypheneKappa-type opioid receptortarget
DB00647DextropropoxypheneCytochrome P450 2D6enzyme
DB00647DextropropoxypheneCytochrome P450 3A4enzyme
DB00647DextropropoxypheneCytochrome P450 2C8enzyme
DB00647DextropropoxypheneLiver carboxylesterase 1target
DB00652PentazocineMu-type opioid receptortarget
DB00652PentazocineKappa-type opioid receptortarget
DB00652PentazocineSigma non-opioid intracellular receptor 1target
DB00653Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
DB00653Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00656Trazodone5-hydroxytryptamine receptor 2Atarget
DB00656TrazodoneSodium-dependent serotonin transportertarget
DB00656TrazodoneAlpha-1A adrenergic receptortarget
DB00656TrazodoneAlpha-2A adrenergic receptortarget
DB00656TrazodoneHistamine H1 receptortarget
DB00656Trazodone5-hydroxytryptamine receptor 1Atarget
DB00656TrazodoneCytochrome P450 2D6enzyme
DB00656TrazodoneCytochrome P450 3A4enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Ctarget
DB00656TrazodoneAlpha-1-acid glycoprotein 1carrier
DB00656TrazodoneCytochrome P450 3A5enzyme
DB00656TrazodoneCytochrome P450 3A7enzyme
DB00656TrazodoneMultidrug resistance protein 1transporter
DB00659AcamprosateMetabotropic glutamate receptor 5target
DB00659AcamprosateProton-coupled amino acid transporter 1transporter
DB00659AcamprosateGABA-A receptor (anion channel)target
DB00659AcamprosateGlutamate (NMDA) receptortarget
DB00673AprepitantSubstance-P receptortarget
DB00673AprepitantCytochrome P450 3A4enzyme
DB00673AprepitantCytochrome P450 2C9enzyme
DB00673AprepitantCytochrome P450 3A5enzyme
DB00673AprepitantCytochrome P450 3A7enzyme
DB00673AprepitantCytochrome P450 2C19enzyme
DB00674GalantamineCytochrome P450 3A4enzyme
DB00674GalantamineCytochrome P450 2D6enzyme
DB00674GalantamineAcetylcholine receptor subunit alphatarget
DB00674GalantamineAcetylcholine receptor subunit betatarget
DB00674GalantamineAcetylcholine receptor subunit deltatarget
DB00674GalantamineAcetylcholine receptor subunit gammatarget
DB00674GalantamineAcetylcholine receptor subunit epsilontarget
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-4target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-5target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-6target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-7target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-9target
DB00674GalantamineNeuronal acetylcholine receptor subunit alpha-10target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-2target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-3target
DB00674GalantamineNeuronal acetylcholine receptor subunit beta-4target
DB00679ThioridazineAlpha-1A adrenergic receptortarget
DB00679ThioridazineD(2) dopamine receptortarget
DB00679Thioridazine5-hydroxytryptamine receptor 2Atarget
DB00679ThioridazineD(1A) dopamine receptortarget
DB00679ThioridazineCytochrome P450 2C19enzyme
DB00679ThioridazineCytochrome P450 2D6enzyme
DB00679ThioridazineAlpha-1B adrenergic receptortarget
DB00679ThioridazinePotassium voltage-gated channel subfamily H member 2target
DB00679ThioridazineCytochrome P450 2C8enzyme
DB00679ThioridazineCytochrome P450 2E1enzyme
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-1target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-5target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-3target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-2target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-4target
DB00683MidazolamGamma-aminobutyric acid receptor subunit alpha-6target
DB00683MidazolamCytochrome P450 3A4enzyme
DB00683MidazolamCytochrome P450 3A5enzyme
DB00683MidazolamUDP-glucuronosyltransferase 1-4enzyme
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-4target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit alpha-6target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit pitarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00690FlurazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00690FlurazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00690FlurazepamCytochrome P450 3A4enzyme
DB00690FlurazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00690FlurazepamMultidrug resistance protein 1transporter
DB00690FlurazepamCytochrome P450 2E1enzyme
DB00690FlurazepamCytochrome P450 2A6enzyme
DB00690FlurazepamSolute carrier family 22 member 2transporter
DB00696ErgotamineAlpha-1A adrenergic receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Dtarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Btarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Atarget
DB00696ErgotamineAlpha-2A adrenergic receptortarget
DB00696ErgotamineD(2) dopamine receptortarget
DB00696ErgotamineAlpha-2B adrenergic receptortarget
DB00696ErgotamineSodium-dependent noradrenaline transportertarget
DB00696ErgotamineCytochrome P450 3A4enzyme
DB00696ErgotamineAlpha-1B adrenergic receptortarget
DB00696ErgotamineAlpha-1D adrenergic receptortarget
DB00696ErgotamineMultidrug resistance protein 1transporter
DB00696ErgotamineD(1) dopamine receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Atarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Ftarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Ctarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Btarget
DB00697TizanidineAlpha-2 adrenergic receptorstarget
DB00697TizanidineCytochrome P450 1A2enzyme
DB00697TizanidineAlpha-1 adrenergic receptorstarget
DB00699NicergolineAlpha-1A adrenergic receptortarget
DB00699NicergolineCytochrome P450 2D6enzyme
DB00704NaltrexoneMu-type opioid receptortarget
DB00704NaltrexoneKappa-type opioid receptortarget
DB00704NaltrexoneDelta-type opioid receptortarget
DB00704NaltrexoneHCG20471, isoform CRA_ctarget
DB00704NaltrexoneUDP-glucuronosyltransferase 1-1enzyme
DB00708SufentanilMu-type opioid receptortarget
DB00708SufentanilDelta-type opioid receptortarget
DB00708SufentanilKappa-type opioid receptortarget
DB00708SufentanilCytochrome P450 3A4enzyme
DB00712FlurbiprofenProstaglandin G/H synthase 2target
DB00712FlurbiprofenProstaglandin G/H synthase 1target
DB00712FlurbiprofenCytochrome P450 2C9enzyme
DB00712FlurbiprofenSerum albumincarrier
DB00712FlurbiprofenMultidrug resistance-associated protein 4transporter
DB00712FlurbiprofenSolute carrier family 22 member 6transporter
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
DB00714ApomorphineD(2) dopamine receptortarget
DB00714ApomorphineD(1A) dopamine receptortarget
DB00714ApomorphineD(4) dopamine receptortarget
DB00714ApomorphineD(3) dopamine receptortarget
DB00714ApomorphineD(1B) dopamine receptortarget
DB00714ApomorphineNeuron-specific vesicular protein calcyontarget
DB00714ApomorphineAlpha-2C adrenergic receptortarget
DB00714ApomorphineAlpha-2B adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Ctarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Atarget
DB00714Apomorphine5-hydroxytryptamine receptor 2Btarget
DB00714ApomorphineAlpha-2A adrenergic receptortarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Dtarget
DB00714Apomorphine5-hydroxytryptamine receptor 1Btarget
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineMuscarinic acetylcholine receptor M1target
DB00715ParoxetineMuscarinic acetylcholine receptor M2target
DB00715ParoxetineMuscarinic acetylcholine receptor M3target
DB00715ParoxetineMuscarinic acetylcholine receptor M4target
DB00715ParoxetineMuscarinic acetylcholine receptor M5target
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineMultidrug resistance protein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 2C8enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00721ProcaineSodium channel protein type 10 subunit alphatarget
DB00721ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
DB00721Procaine5-hydroxytryptamine receptor 3Atarget
DB00721ProcaineSodium-dependent dopamine transportertarget
DB00721ProcaineNeuronal acetylcholine receptor subunit alpha-2target
DB00721ProcaineCalcium-activated potassium channeltarget
DB00721ProcainePhospholipase A2target
DB00721ProcaineMonoamine oxidasetarget
DB00726TrimipramineSodium-dependent serotonin transportertarget
DB00726TrimipramineSodium-dependent noradrenaline transportertarget
DB00726TrimipramineCytochrome P450 2D6enzyme
DB00726TrimipramineSodium-dependent dopamine transportertarget
DB00726Trimipramine5-hydroxytryptamine receptor 2Atarget
DB00726Trimipramine5-hydroxytryptamine receptor 1Atarget
DB00726TrimipramineAlpha-1A adrenergic receptortarget
DB00726TrimipramineAlpha-1B adrenergic receptortarget
DB00726TrimipramineD(2) dopamine receptortarget
DB00726TrimipramineAlpha-2B adrenergic receptortarget
DB00726TrimipramineHistamine H1 receptortarget
DB00726TrimipramineCytochrome P450 2C19enzyme
DB00726TrimipramineCytochrome P450 3A4enzyme
DB00726TrimipramineMultidrug resistance protein 1transporter
DB00726TrimipramineCytochrome P450 2C9enzyme
DB00726Trimipramine5-hydroxytryptamine receptor 2Ctarget
DB00726Trimipramine5-hydroxytryptamine receptor 3Atarget
DB00726Trimipramine5-hydroxytryptamine receptor 1Dtarget
DB00726TrimipramineAlpha-2A adrenergic receptortarget
DB00726TrimipramineD(1) dopamine receptortarget
DB00726TrimipramineBeta adrenergic receptortarget
DB00726TrimipramineMuscarinic acetylcholine receptortarget
DB00726Trimipramine5-hydroxytryptamine receptor 1Ctarget
DB00734RisperidoneHistamine H1 receptortarget
DB00734RisperidoneD(2) dopamine receptortarget
DB00734RisperidoneAlpha-1A adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 2Atarget
DB00734RisperidoneAlpha-1B adrenergic receptortarget
DB00734RisperidoneCytochrome P450 2D6enzyme
DB00734RisperidoneD(1A) dopamine receptortarget
DB00734RisperidoneAlpha-2A adrenergic receptortarget
DB00734RisperidoneAlpha-2B adrenergic receptortarget
DB00734RisperidoneAlpha-2C adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 1Atarget
DB00734Risperidone5-hydroxytryptamine receptor 1Dtarget
DB00734Risperidone5-hydroxytryptamine receptor 2Ctarget
DB00734RisperidoneD(3) dopamine receptortarget
DB00734RisperidoneD(4) dopamine receptortarget
DB00734RisperidoneCytochrome P450 3A4enzyme
DB00734RisperidoneCytochrome P450 3A5enzyme
DB00734RisperidoneCytochrome P450 3A7enzyme
DB00734Risperidone5-hydroxytryptamine receptor 7target
DB00734RisperidoneMultidrug resistance protein 1transporter
DB00737MeclizineHistamine H1 receptortarget
DB00737MeclizineNuclear receptor subfamily 1 group I member 3target
DB00740RiluzoleSodium channel protein type 5 subunit alphatarget
DB00740RiluzoleCytochrome P450 1A2enzyme
DB00740RiluzoleCystine/glutamate transportertarget
DB00740RiluzoleATP-binding cassette sub-family G member 2transporter
DB00740RiluzoleCytochrome P450 1A1enzyme
DB00744ZileutonArachidonate 5-lipoxygenasetarget
DB00744ZileutonCytochrome P450 2C9enzyme
DB00744ZileutonCytochrome P450 1A2enzyme
DB00744ZileutonCytochrome P450 3A4enzyme
DB00744ZileutonProstaglandin G/H synthase 1enzyme
DB00744ZileutonUDP-glucuronosyltransferase 1-9enzyme
DB00744ZileutonSerum albumincarrier
DB00745ModafinilSodium-dependent dopamine transportertarget
DB00745ModafinilAlpha-1B adrenergic receptortarget
DB00745ModafinilCytochrome P450 3A4enzyme
DB00745ModafinilCytochrome P450 2C19enzyme
DB00745ModafinilCytochrome P450 1A2enzyme
DB00745ModafinilCytochrome P450 2B6enzyme
DB00745ModafinilCytochrome P450 2C9enzyme
DB00745ModafinilCytochrome P450 3A5enzyme
DB00747ScopolamineMuscarinic acetylcholine receptor M1target
DB00747ScopolamineSucrase-isomaltase, intestinaltarget
DB00747ScopolamineMuscarinic acetylcholine receptor M2target
DB00747ScopolamineMuscarinic acetylcholine receptor M3target
DB00747ScopolamineMuscarinic acetylcholine receptor M4target
DB00747ScopolamineMuscarinic acetylcholine receptor M5target
DB00747ScopolamineMultidrug resistance protein 1transporter
DB00747ScopolamineNeuronal acetylcholine receptor subunit alpha-4target
DB00747ScopolamineNeuronal acetylcholine receptor subunit beta-2target
DB00749EtodolacProstaglandin G/H synthase 1target
DB00749EtodolacProstaglandin G/H synthase 2target
DB00749EtodolacCytochrome P450 2C9enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-9enzyme
DB00749EtodolacRetinoic acid receptor RXR-alphatarget
DB00749EtodolacSerum albumincarrier
DB00749EtodolacSolute carrier family 22 member 6transporter
DB00749EtodolacUDP-glucuronosyltransferase 1-3enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-10enzyme
DB00749EtodolacUDP-glucuronosyltransferase 2B7enzyme
DB00750PrilocaineSodium channel protein type 5 subunit alphatarget
DB00752TranylcypromineAmine oxidase [flavin-containing] Btarget
DB00752TranylcypromineAmine oxidase [flavin-containing] Atarget
DB00752TranylcypromineCytochrome P450 2C19enzyme
DB00752TranylcypromineCytochrome P450 2A6enzyme
DB00752TranylcypromineCytochrome P450 2D6enzyme
DB00752TranylcypromineCytochrome P450 1A2enzyme
DB00752TranylcypromineCytochrome P450 2C9enzyme
DB00752TranylcypromineCytochrome P450 2E1enzyme
DB00752TranylcypromineCytochrome P450 3A4enzyme
DB00753IsofluraneCalcium-transporting ATPase type 2C member 1target
DB00753IsofluraneATP synthase subunit delta, mitochondrialtarget
DB00753IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB00753IsofluranePotassium voltage-gated channel subfamily A member 1target
DB00753IsofluraneGlutamate receptor 1target
DB00753IsofluraneGlycine receptor subunit alpha-1target
DB00753IsofluraneCytochrome P450 2E1enzyme
DB00753IsofluraneSerum albumincarrier
DB00753IsofluraneCytochrome P450 2B6enzyme
DB00753IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
DB00753IsofluraneGABA-A receptor (anion channel)target
DB00753IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
DB00753IsofluraneNeuronal acetylcholine receptor subunit beta-2target
DB00754EthotoinSodium channel protein type 5 subunit alphatarget
DB00754EthotoinNuclear receptor subfamily 1 group I member 2target
DB00754EthotoinThyroxine-binding globulincarrier
DB00757Dolasetron5-hydroxytryptamine receptor 3Atarget
DB00757DolasetronCytochrome P450 3A4enzyme
DB00757DolasetronCytochrome P450 2D6enzyme
DB00757DolasetronCytochrome P450 2C9enzyme
DB00768OlopatadineHistamine H1 receptortarget
DB00768OlopatadineProtein S100-A1target
DB00768OlopatadineProtein S100-A12target
DB00768OlopatadineProtein S100-Btarget
DB00768OlopatadineProtein S100-A13target
DB00768OlopatadineProtein S100-A2target
DB00768OlopatadineCytochrome P450 3A4enzyme
DB00776OxcarbazepineSodium channel protein type 5 subunit alphatarget
DB00776OxcarbazepineCytochrome P450 2C19enzyme
DB00776OxcarbazepineCytochrome P450 3A4enzyme
DB00776OxcarbazepineCytochrome P450 3A5enzyme
DB00776OxcarbazepineSerum albumincarrier
DB00776OxcarbazepineUDP-glucuronosyltransferase 1-1enzyme
DB00776OxcarbazepineMultidrug resistance protein 1transporter
DB00780PhenelzineMembrane primary amine oxidasetarget
DB00780PhenelzineAmine oxidase [flavin-containing] Btarget
DB00780PhenelzineAmine oxidase [flavin-containing] Atarget
DB00780PhenelzineAmine oxidase [flavin-containing] Aenzyme
DB00780PhenelzineAmine oxidase [flavin-containing] Benzyme
DB00780PhenelzineCytochrome P450 2E1enzyme
DB00780Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
DB00780PhenelzineGlutamic acid decarboxylasetarget
DB00780PhenelzineAlanine aminotransferase 1target
DB00780PhenelzineAlanine aminotransferase 2target
DB00780PhenelzineCytochrome P450 2C19enzyme
DB00780PhenelzineCytochrome P450 2C8enzyme
DB00780PhenelzineCytochrome P450 3A4enzyme
DB00780PhenelzineCytochrome P450 3A43enzyme
DB00780PhenelzineCytochrome P450 3A5enzyme
DB00780PhenelzineCytochrome P450 3A7enzyme
DB00780PhenelzineCytochrome P450 2D6enzyme
DB00784Mefenamic acidProstaglandin G/H synthase 2target
DB00784Mefenamic acidProstaglandin G/H synthase 1target
DB00784Mefenamic acidCytochrome P450 2C9enzyme
DB00784Mefenamic acidCytochrome P450 2C8enzyme
DB00784Mefenamic acidSerum albumincarrier
DB00784Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-1enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenMultidrug resistance protein 1transporter
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
DB00794PrimidoneCytochrome P450 2C19enzyme
DB00794PrimidoneCytochrome P450 1A2enzyme
DB00794PrimidoneCytochrome P450 2B6enzyme
DB00794PrimidoneCytochrome P450 2C8enzyme
DB00794PrimidoneCytochrome P450 2C9enzyme
DB00794PrimidoneCytochrome P450 3A4enzyme
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
DB00794PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
DB00794PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
DB00794PrimidoneGlutamate receptor 2target
DB00794PrimidoneGlutamate receptor ionotropic, kainate 2target
DB00794PrimidoneGABA-A receptor (anion channel)target
DB00794PrimidoneUDP-glucuronosyltransferase 1-1enzyme
DB00795SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
DB00795SulfasalazineCystine/glutamate transportertarget
DB00795SulfasalazineATP-binding cassette sub-family G member 2transporter
DB00795SulfasalazineCanalicular multispecific organic anion transporter 1transporter
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00795SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00795SulfasalazineProstaglandin G/H synthase 2target
DB00795SulfasalazinePeroxisome proliferator-activated receptor gammatarget
DB00795SulfasalazineProstaglandin G/H synthase 1target
DB00795SulfasalazineArachidonate 5-lipoxygenasetarget
DB00795SulfasalazineProton-coupled folate transportertransporter
DB00795SulfasalazineThromboxane-A synthasetarget
DB00795SulfasalazinePhospholipase A2target
DB00795SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
DB00795SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
DB00795SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
DB00801HalazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00801HalazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00801HalazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00801HalazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00801HalazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00801HalazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00801HalazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00801HalazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00801HalazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00801HalazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00801HalazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00801HalazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00801HalazepamGamma-aminobutyric acid receptor subunit pitarget
DB00801HalazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00801HalazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00801HalazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00801HalazepamGABA-A receptor (anion channel)target
DB00802AlfentanilMu-type opioid receptortarget
DB00802AlfentanilCytochrome P450 3A4enzyme
DB00802AlfentanilCytochrome P450 3A5enzyme
DB00802AlfentanilAlpha-1-acid glycoprotein 1carrier
DB00802AlfentanilSerum albumincarrier
DB00802AlfentanilCytochrome P450 3A7enzyme
DB00802AlfentanilMultidrug resistance protein 1transporter
DB00805MinaprineD(1A) dopamine receptortarget
DB00805MinaprineD(2) dopamine receptortarget
DB00805Minaprine5-hydroxytryptamine receptor 2Atarget
DB00805Minaprine5-hydroxytryptamine receptor 2Btarget
DB00805Minaprine5-hydroxytryptamine receptor 2Ctarget
DB00805MinaprineSodium-dependent serotonin transportertarget
DB00805MinaprineCytochrome P450 2D6enzyme
DB00805MinaprineMuscarinic acetylcholine receptor M1target
DB00805MinaprineAmine oxidase [flavin-containing] Atarget
DB00807ProparacaineSodium channel protein type 10 subunit alphatarget
DB00810BiperidenNeuronal acetylcholine receptor subunit alpha-2target
DB00810BiperidenMuscarinic acetylcholine receptor M1target
DB00810BiperidenCytochrome P450 2D6enzyme
DB00812PhenylbutazoneProstaglandin G/H synthase 2target
DB00812PhenylbutazoneProstacyclin synthasetarget
DB00812PhenylbutazoneCytochrome P450 2C9enzyme
DB00812PhenylbutazoneSolute carrier family 22 member 6transporter
DB00812PhenylbutazoneSolute carrier family 22 member 8transporter
DB00812PhenylbutazoneSolute carrier family 22 member 11transporter
DB00812PhenylbutazoneProstaglandin G/H synthase 1target
DB00812PhenylbutazoneCytochrome P450 3A4enzyme
DB00813FentanylMu-type opioid receptortarget
DB00813FentanylDelta-type opioid receptortarget
DB00813FentanylCytochrome P450 3A4enzyme
DB00813FentanylCytochrome P450 3A5enzyme
DB00813FentanylCytochrome P450 3A7enzyme
DB00813FentanylMultidrug resistance protein 1transporter
DB00813FentanylKappa-type opioid receptortarget
DB00813FentanylMultidrug resistance protein 1target
DB00814MeloxicamProstaglandin G/H synthase 2target
DB00814MeloxicamCytochrome P450 2C9enzyme
DB00814MeloxicamProstaglandin G/H synthase 1target
DB00814MeloxicamCytochrome P450 3A4enzyme
DB00814MeloxicamMultidrug resistance-associated protein 4transporter
DB00814Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00814MeloxicamCytochrome P450 2C8enzyme
DB00818PropofolCytochrome P450 2B6enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-1enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-9enzyme
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-2target
DB00818PropofolGamma-aminobutyric acid receptor subunit beta-3target
DB00818PropofolSerum albumincarrier
DB00818PropofolSodium channel protein type 4 subunit alphatarget
DB00818PropofolSodium channel protein type 2 subunit alphatarget
DB00818PropofolFatty-acid amide hydrolase 1enzyme
DB00818PropofolCytochrome P450 2C9enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-8enzyme
DB00818PropofolCytochrome P450 2E1enzyme
DB00818PropofolCytochrome P450 1B1enzyme
DB00818PropofolCytochrome P450 1A1enzyme
DB00818PropofolCytochrome P450 1A2enzyme
DB00818PropofolCytochrome P450 2C18enzyme
DB00818PropofolCytochrome P450 2C19enzyme
DB00818PropofolCytochrome P450 2C8enzyme
DB00818PropofolUDP-glucuronosyltransferase 1-6enzyme
DB00818PropofolGABA-A receptor (anion channel)target
DB00819AcetazolamideCarbonic anhydrase 1target
DB00819AcetazolamideCarbonic anhydrase 14target
DB00819AcetazolamideSolute carrier family 22 member 6transporter
DB00819AcetazolamideCarbonic anhydrase 2target
DB00819AcetazolamideCarbonic anhydrase 3target
DB00819AcetazolamideCarbonic anhydrase 4target
DB00819AcetazolamideCytochrome P450 3A4enzyme
DB00819AcetazolamideCarbonic anhydrase 7target
DB00819AcetazolamideCarbonic anhydrase 12target
DB00821CarprofenProstaglandin G/H synthase 2target
DB00821CarprofenProstaglandin G/H synthase 1target
DB00821CarprofenSolute carrier family 22 member 6transporter
DB00822DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DB00822DisulfiramCytochrome P450 2E1enzyme
DB00822DisulfiramDopamine beta-hydroxylasetarget
DB00822DisulfiramCytochrome P450 3A4enzyme
DB00822DisulfiramCytochrome P450 3A5enzyme
DB00822DisulfiramBile salt export pumptransporter
DB00829DiazepamTranslocator proteintarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00829DiazepamCytochrome P450 3A4enzyme
DB00829DiazepamSerum albumincarrier
DB00829DiazepamCytochrome P450 2C9enzyme
DB00829DiazepamCytochrome P450 2C19enzyme
DB00829DiazepamCytochrome P450 3A5enzyme
DB00829DiazepamCytochrome P450 3A7enzyme
DB00829DiazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit pitarget
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00829DiazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00829DiazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00829DiazepamMultidrug resistance protein 1transporter
DB00829DiazepamCytochrome P450 2B6enzyme
DB00829DiazepamProstaglandin G/H synthase 1enzyme
DB00829DiazepamCytochrome P450 2C18enzyme
DB00829DiazepamCytochrome P450 2C8enzyme
DB00829DiazepamCytochrome P450 2E1enzyme
DB00829DiazepamGABA-A receptor (anion channel)target
DB00830PhenmetrazineSodium-dependent noradrenaline transportertarget
DB00830PhenmetrazineSodium-dependent dopamine transportertarget
DB00831TrifluoperazineD(2) dopamine receptortarget
DB00831TrifluoperazineAlpha-1A adrenergic receptortarget
DB00831TrifluoperazineNeuron-specific vesicular protein calcyontarget
DB00831TrifluoperazineXanthine dehydrogenase/oxidaseenzyme
DB00831TrifluoperazineUDP-glucuronosyltransferase 1-4enzyme
DB00831TrifluoperazineCytochrome P450 1A2enzyme
DB00831TrifluoperazineMultidrug resistance protein 1transporter
DB00831TrifluoperazineTroponin C, slow skeletal and cardiac musclestarget
DB00831TrifluoperazineProtein S100-A4target
DB00837ProgabideGamma-aminobutyric acid receptor subunit alpha-1target
DB00837ProgabideGamma-aminobutyric acid type B receptor subunit 1target
DB00842OxazepamGamma-aminobutyric acid receptor subunit alpha-1target
DB00842OxazepamGamma-aminobutyric acid receptor subunit alpha-2target
DB00842OxazepamGamma-aminobutyric acid receptor subunit alpha-3target
DB00842OxazepamGamma-aminobutyric acid receptor subunit alpha-4target
DB00842OxazepamGamma-aminobutyric acid receptor subunit alpha-5target
DB00842OxazepamGamma-aminobutyric acid receptor subunit alpha-6target
DB00842OxazepamGamma-aminobutyric acid receptor subunit beta-1target
DB00842OxazepamGamma-aminobutyric acid receptor subunit beta-2target
DB00842OxazepamGamma-aminobutyric acid receptor subunit beta-3target
DB00842OxazepamGamma-aminobutyric acid receptor subunit gamma-1target
DB00842OxazepamGamma-aminobutyric acid receptor subunit gamma-2target
DB00842OxazepamGamma-aminobutyric acid receptor subunit gamma-3target
DB00842OxazepamGamma-aminobutyric acid receptor subunit deltatarget
DB00842OxazepamGamma-aminobutyric acid receptor subunit epsilontarget
DB00842OxazepamGamma-aminobutyric acid receptor subunit pitarget
DB00842OxazepamGamma-aminobutyric acid receptor subunit rho-1target
DB00842OxazepamGamma-aminobutyric acid receptor subunit rho-2target
DB00842OxazepamGamma-aminobutyric acid receptor subunit thetatarget
DB00842OxazepamGamma-aminobutyric acid receptor subunit rho-3target
DB00842OxazepamCytochrome P450 3A4enzyme
DB00842OxazepamCytochrome P450 3A43enzyme
DB00842OxazepamUDP-glucuronosyltransferase 2B15enzyme
DB00842OxazepamUDP-glucuronosyltransferase 2B7enzyme
DB00842OxazepamUDP-glucuronosyltransferase 1-9enzyme
DB00842OxazepamGABA-A receptor (anion channel)target
DB00843Donepezil5-hydroxytryptamine receptor 2Atarget
DB00843DonepezilCytochrome P450 3A4enzyme
DB00843DonepezilCytochrome P450 2D6enzyme
DB00843DonepezilCytochrome P450 2C9enzyme
DB00844NalbuphineKappa-type opioid receptortarget
DB00844NalbuphineMu-type opioid receptortarget
DB00844NalbuphineDelta-type opioid receptortarget
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB00849MethylphenobarbitalCytochrome P450 2C19enzyme
DB00849MethylphenobarbitalCytochrome P450 2B6enzyme
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
DB00849MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
DB00849MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB00849MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB00849MethylphenobarbitalGlutamate receptor 2target
DB00849MethylphenobarbitalGlutamate receptor ionotropic, kainate 2target
DB00849MethylphenobarbitalNuclear receptor subfamily 1 group I member 2target
DB00850PerphenazineD(1A) dopamine receptortarget
DB00850PerphenazineD(2) dopamine receptortarget
DB00850PerphenazineCytochrome P450 2D6enzyme
DB00850PerphenazineCytochrome P450 1A2enzyme
DB00850PerphenazineCytochrome P450 2B6enzyme
DB00850PerphenazineCytochrome P450 2C18enzyme
DB00850PerphenazineCytochrome P450 2C19enzyme
DB00850PerphenazineCytochrome P450 2C8enzyme
DB00850PerphenazineCytochrome P450 2C9enzyme
DB00850PerphenazineCytochrome P450 3A4enzyme
DB00854LevorphanolMu-type opioid receptortarget
DB00854LevorphanolDelta-type opioid receptortarget
DB00854LevorphanolKappa-type opioid receptortarget
DB00856ChlorphenesinCYP2B proteinenzyme
DB00856ChlorphenesinCytochrome P450 19A1enzyme
DB00856ChlorphenesinCytochrome P450 3A4enzyme
DB00856ChlorphenesinXanthine dehydrogenase/oxidaseenzyme
DB00856ChlorphenesinProstaglandin G/H synthase 2enzyme
DB00861DiflunisalProstaglandin G/H synthase 1target
DB00861DiflunisalProstaglandin G/H synthase 2target
DB00861DiflunisalSerum albumincarrier
DB00861DiflunisalSolute carrier family 22 member 6transporter
DB00861DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DB00861DiflunisalUDP-glucuronosyltransferase 1-9enzyme
DB00865BenzphetamineAlpha-2A adrenergic receptortarget
DB00865BenzphetamineAlpha-1A adrenergic receptortarget
DB00865BenzphetamineCytochrome P450 3A4enzyme
DB00865BenzphetamineCytochrome P450 2B6enzyme
DB00865BenzphetamineNADPH--cytochrome P450 reductaseenzyme
DB00865BenzphetamineSynaptic vesicular amine transportertarget
DB00865BenzphetamineSodium-dependent dopamine transportertarget
DB00868BenzonatateSodium channel protein type 5 subunit alphatarget
DB00870SuprofenProstaglandin G/H synthase 1target
DB00870SuprofenProstaglandin G/H synthase 2target
DB00870SuprofenCytochrome P450 2C9enzyme
DB00870SuprofenUDP-glucuronosyltransferase 1-1enzyme
DB00870SuprofenUDP-glucuronosyltransferase 2B7enzyme
DB00875FlupentixolAlpha-1A adrenergic receptortarget
DB00875FlupentixolD(2) dopamine receptortarget
DB00875FlupentixolD(1A) dopamine receptortarget
DB00875FlupentixolAromatic-L-amino-acid decarboxylaseenzyme
DB00875Flupentixol5-hydroxytryptamine receptor 2Atarget
DB00875FlupentixolMultidrug resistance protein 1transporter
DB00875FlupentixolMuscarinic acetylcholine receptor M1target
DB00889Granisetron5-hydroxytryptamine receptor 3Atarget
DB00889GranisetronCytochrome P450 3A4enzyme
DB00889GranisetronCytochrome P450 1A1enzyme
DB00892OxybuprocaineSodium channel protein type 10 subunit alphatarget
DB00897TriazolamTranslocator proteintarget
DB00897TriazolamCytochrome P450 3A4enzyme
DB00897TriazolamCytochrome P450 3A5enzyme
DB00897TriazolamCytochrome P450 3A7enzyme
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-4target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-5target
DB00897TriazolamGamma-aminobutyric acid receptor subunit alpha-6target
DB00897TriazolamGamma-aminobutyric acid receptor subunit beta-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit beta-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit beta-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit gamma-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit gamma-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit gamma-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit deltatarget
DB00897TriazolamGamma-aminobutyric acid receptor subunit epsilontarget
DB00897TriazolamGamma-aminobutyric acid receptor subunit pitarget
DB00897TriazolamGamma-aminobutyric acid receptor subunit rho-1target
DB00897TriazolamGamma-aminobutyric acid receptor subunit rho-2target
DB00897TriazolamGamma-aminobutyric acid receptor subunit rho-3target
DB00897TriazolamGamma-aminobutyric acid receptor subunit thetatarget
DB00897TriazolamCytochrome P450 2C8enzyme
DB00897TriazolamGABA-A receptor (anion channel)target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-1target
DB00898EthanolGlutamate receptor ionotropic, NMDA 3Atarget
DB00898EthanolGlycine receptor subunit alpha-1target
DB00898EthanolGlycine receptor subunit alpha-2target
DB00898EthanolCytochrome P450 2E1enzyme
DB00898EthanolCytochrome P450 1A1enzyme
DB00898EthanolCytochrome P450 1A2enzyme
DB00898EthanolCytochrome P450 2B6enzyme
DB00898EthanolCytochrome P450 2C19enzyme
DB00898EthanolCytochrome P450 2C9enzyme
DB00898EthanolCytochrome P450 3A4enzyme
DB00898EthanolCytochrome P450 4A11enzyme
DB00898EthanolAlcohol dehydrogenase 1Aenzyme
DB00898EthanolAlcohol dehydrogenase 1Benzyme
DB00898EthanolAlcohol dehydrogenase 1Cenzyme
DB00898EthanolAlcohol dehydrogenase class-3enzyme
DB00898EthanolVoltage-dependent L-type calcium channel subunit beta-1target
DB00898Ethanol5-hydroxytryptamine receptor 3Atarget
DB00898EthanolAlcohol dehydrogenase 4enzyme
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-2target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-10target
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-5target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-4target
DB00898EthanolAlcohol dehydrogenase class 4 mu/sigma chainenzyme
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-3target
DB00898EthanolGlutamate receptor 1target
DB00898EthanolVoltage-dependent calcium channel gamma-1 subunittarget
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-2target
DB00898EthanolGamma-aminobutyric acid receptor subunit alpha-6target
DB00898EthanolGlutamate receptor 2target
DB00898EthanolGlutamate receptor 4target
DB00898EthanolGlutamate receptor 3target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-4target
DB00898EthanolNeuronal acetylcholine receptor subunit beta-2target
DB00898EthanolG protein-activated inward rectifier potassium channel 1target
DB00898EthanolG protein-activated inward rectifier potassium channel 2target
DB00898EthanolVascular cell adhesion protein 1target
DB00898EthanolEquilibrative nucleoside transporter 1target
DB00898EthanolG protein-activated inward rectifier potassium channel 4target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-7target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-9target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-1target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit beta-2target
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00898EthanolAlcohol dehydrogenase 6enzyme
DB00898EthanolNeuronal acetylcholine receptor subunit beta-4target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-3target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-5target
DB00898EthanolNeuronal acetylcholine receptor subunit alpha-6target
DB00898EthanolNeuronal acetylcholine receptor subunit beta-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit gamma-1target
DB00898EthanolGamma-aminobutyric acid receptor subunit gamma-3target
DB00898EthanolGamma-aminobutyric acid receptor subunit epsilontarget
DB00898EthanolGamma-aminobutyric acid receptor subunit pitarget
DB00898EthanolGamma-aminobutyric acid receptor subunit thetatarget
DB00898EthanolGamma-aminobutyric acid receptor subunit deltatarget
DB00898EthanolAlcohol dehydrogenase [NADP(+)]enzyme
DB00898EthanolEquilibrative nucleoside transporter 2target
DB00898Ethanol5-hydroxytryptamine receptor 3Etarget
DB00898Ethanol5-hydroxytryptamine receptor 3Btarget
DB00898Ethanol5-hydroxytryptamine receptor 3Dtarget
DB00898Ethanol5-hydroxytryptamine receptor 3Ctarget
DB00898EthanolVoltage-dependent calcium channel gamma-2 subunittarget
DB00898EthanolG protein-activated inward rectifier potassium channel 3target
DB00898EthanolNeural cell adhesion molecule L1target
DB00899RemifentanilMu-type opioid receptortarget
DB00899RemifentanilDelta-type opioid receptortarget
DB00899RemifentanilKappa-type opioid receptortarget
DB00904Ondansetron5-hydroxytryptamine receptor 3Atarget
DB00904OndansetronCytochrome P450 3A4enzyme
DB00904OndansetronCytochrome P450 1A2enzyme
DB00904OndansetronCytochrome P450 2D6enzyme
DB00904OndansetronCytochrome P450 3A5enzyme
DB00904OndansetronCytochrome P450 3A7enzyme
DB00904Ondansetron5-hydroxytryptamine receptor 4target
DB00904Ondansetron5-hydroxytryptamine receptor 1Atarget
DB00904Ondansetron5-hydroxytryptamine receptor 1Btarget
DB00904OndansetronMu-type opioid receptortarget
DB00904OndansetronCytochrome P450 2C9enzyme
DB00904OndansetronCytochrome P450 2E1enzyme
DB00906TiagabineSodium- and chloride-dependent GABA transporter 1target
DB00906TiagabineCytochrome P450 3A4enzyme
DB00906TiagabineUDP-glucuronosyltransferase 1-1enzyme
DB00907CocaineSodium-dependent noradrenaline transportertarget
DB00907CocaineSodium channel protein type 5 subunit alphatarget
DB00907CocaineSodium channel protein type 11 subunit alphatarget
DB00907CocaineSodium channel protein type 10 subunit alphatarget
DB00907CocaineSodium-dependent serotonin transportertarget
DB00907CocaineSodium-dependent dopamine transportertarget
DB00907CocaineCytochrome P450 3A4enzyme
DB00907CocaineMuscarinic acetylcholine receptor M1target
DB00907CocaineMuscarinic acetylcholine receptor M2target
DB00907CocaineCytochrome P450 3A5enzyme
DB00907CocaineCytochrome P450 3A7enzyme
DB00907CocaineCytochrome P450 2D6enzyme
DB00907CocaineSolute carrier family 22 member 2transporter
DB00907CocaineCytochrome P450 2C8enzyme
DB00907CocaineSigma non-opioid intracellular receptor 1target
DB00907CocaineLiver carboxylesterase 1target
DB00909ZonisamideSodium channel protein type 1 subunit alphatarget
DB00909ZonisamideCarbonic anhydrase 1target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00909ZonisamideCytochrome P450 3A4enzyme
DB00909ZonisamideAldehyde oxidaseenzyme
DB00909ZonisamideAmine oxidase [flavin-containing] Btarget
DB00909ZonisamideCarbonic anhydrase 2target
DB00909ZonisamideCarbonic anhydrase 3target
DB00909ZonisamideCarbonic anhydrase 4target
DB00909ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
DB00909ZonisamideCarbonic anhydrase 6target
DB00909ZonisamideCarbonic anhydrase 7target
DB00909ZonisamideCarbonic anhydrase-related proteintarget
DB00909ZonisamideCarbonic anhydrase 9target
DB00909ZonisamideCarbonic anhydrase-related protein 10target
DB00909ZonisamideCarbonic anhydrase-related protein 11target
DB00909ZonisamideCarbonic anhydrase 12target
DB00909ZonisamideCarbonic anhydrase 13target
DB00909ZonisamideCarbonic anhydrase 14target
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00909ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00909ZonisamideSodium channel protein type 2 subunit alphatarget
DB00909ZonisamideSodium channel protein type 3 subunit alphatarget
DB00909ZonisamideSodium channel protein type 4 subunit alphatarget
DB00909ZonisamideSodium channel protein type 5 subunit alphatarget
DB00909ZonisamideSodium channel protein type 9 subunit alphatarget
DB00909ZonisamideSodium channel protein type 11 subunit alphatarget
DB00909ZonisamideSodium channel subunit beta-1target
DB00909ZonisamideSodium channel subunit beta-2target
DB00909ZonisamideSodium channel subunit beta-3target
DB00909ZonisamideSodium channel subunit beta-4target
DB00909ZonisamideAmine oxidase [flavin-containing] Atarget
DB00909ZonisamideCytochrome P450 2C19enzyme
DB00909ZonisamideUDP-glucuronosyltransferase 1-1enzyme
DB00909ZonisamideCytochrome P450 3A5enzyme
DB00915AmantadineD(2) dopamine receptortarget
DB00915AmantadineMatrix protein 2target
DB00915AmantadineAromatic-L-amino-acid decarboxylaseenzyme
DB00915AmantadineAmine oxidase [flavin-containing] Benzyme
DB00915AmantadineSolute carrier family 22 member 2transporter
DB00915AmantadineSolute carrier family 22 member 1transporter
DB00915AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-7target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-4target
DB00915AmantadineNeuronal acetylcholine receptor subunit alpha-3target
DB00921BuprenorphineKappa-type opioid receptortarget
DB00921BuprenorphineMu-type opioid receptortarget
DB00921BuprenorphineCytochrome P450 3A4enzyme
DB00921BuprenorphineCytochrome P450 2D6enzyme
DB00921BuprenorphineMultidrug resistance protein 1transporter
DB00921BuprenorphineATP-binding cassette sub-family G member 2transporter
DB00921BuprenorphineCytochrome P450 2C9enzyme
DB00921BuprenorphineCytochrome P450 3A5enzyme
DB00921BuprenorphineCytochrome P450 2C8enzyme
DB00921BuprenorphineCytochrome P450 3A7enzyme
DB00921BuprenorphineUDP-glucuronosyltransferase 1-9enzyme
DB00921BuprenorphineDelta-type opioid receptortarget
DB00921BuprenorphineCytochrome P450 2A6enzyme
DB00921BuprenorphineCytochrome P450 2C18enzyme
DB00921BuprenorphineCytochrome P450 2C19enzyme
DB00921BuprenorphineNociceptin receptortarget
DB00921BuprenorphineUDP-glucuronosyltransferase 1-1enzyme
DB00924Cyclobenzaprine5-hydroxytryptamine receptor 2Atarget
DB00924CyclobenzaprineCytochrome P450 1A2enzyme
DB00924CyclobenzaprineCytochrome P450 3A4enzyme
DB00924CyclobenzaprineCytochrome P450 2D6enzyme
DB00924CyclobenzaprineUDP-glucuronosyltransferase 1-1enzyme
DB00933MesoridazineD(2) dopamine receptortarget
DB00933Mesoridazine5-hydroxytryptamine receptor 2Atarget
DB00933MesoridazineCytochrome P450 2D6enzyme
DB00934MaprotilineHistamine H1 receptortarget
DB00934MaprotilineSodium-dependent noradrenaline transportertarget
DB00934MaprotilineAlpha-1 adrenergic receptorstarget
DB00934MaprotilineCytochrome P450 2D6enzyme
DB00934MaprotilineAlpha-1-acid glycoprotein 1carrier
DB00934MaprotilineMuscarinic acetylcholine receptor M1target
DB00934MaprotilineMuscarinic acetylcholine receptor M2target
DB00934MaprotilineMuscarinic acetylcholine receptor M3target
DB00934MaprotilineMuscarinic acetylcholine receptor M4target
DB00934MaprotilineMuscarinic acetylcholine receptor M5target
DB00934MaprotilineCytochrome P450 1A2enzyme
DB00934Maprotiline5-hydroxytryptamine receptor 2Atarget
DB00934Maprotiline5-hydroxytryptamine receptor 2Ctarget
DB00934Maprotiline5-hydroxytryptamine receptor 7target
DB00934MaprotilineD(2) dopamine receptortarget
DB00934MaprotilineAlpha-2 adrenergic receptorstarget
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB00937DiethylpropionSodium-dependent noradrenaline transportertarget
DB00937DiethylpropionSodium-dependent dopamine transportertarget
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB00949FelbamateGlutamate receptor ionotropic, NMDA 3Atarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Btarget
DB00949FelbamateGlutamate receptor ionotropic, NMDA 2Atarget
DB00949FelbamateCytochrome P450 2C19enzyme
DB00949FelbamateCytochrome P450 3A4enzyme
DB00949FelbamateCytochrome P450 2E1enzyme
DB00949FelbamateCytochrome P450 2C9enzyme
DB00956HydrocodoneMu-type opioid receptortarget
DB00956HydrocodoneDelta-type opioid receptortarget
DB00956HydrocodoneCytochrome P450 3A4enzyme
DB00956HydrocodoneCytochrome P450 2D6enzyme
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneMultidrug resistance protein 1transporter
DB00961MepivacaineSodium channel protein type 10 subunit alphatarget
DB00962ZaleplonTranslocator proteintarget
DB00962ZaleplonGamma-aminobutyric acid receptor subunit alpha-1target
DB00962ZaleplonCytochrome P450 3A4enzyme
DB00962ZaleplonAldehyde oxidaseenzyme
DB00962ZaleplonCytochrome P450 3A5enzyme
DB00962ZaleplonCytochrome P450 3A7enzyme
DB00963BromfenacProstaglandin G/H synthase 1target
DB00963BromfenacProstaglandin G/H synthase 2target
DB00963BromfenacProstaglandin G/H synthase 2enzyme
DB00985DimenhydrinateHistamine H1 receptortarget
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M1target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M3target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M2target
DB00989RivastigmineCytochrome P450 3A4enzyme
DB00991OxaprozinProstaglandin G/H synthase 2target
DB00991OxaprozinProstaglandin G/H synthase 1target
DB00996GabapentinAdenosine receptor A1target
DB00996GabapentinVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00996GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
DB00996GabapentinNMDA receptortarget
DB00996GabapentinGamma-aminobutyric acid type B receptor subunit 1target
DB00996GabapentinGamma-aminobutyric acid type B receptor subunit 2target
DB00996GabapentinCytochrome P450 3A4enzyme
DB01002LevobupivacaineSodium channel protein type 10 subunit alphatarget
DB01002LevobupivacaineCytochrome P450 3A4enzyme
DB01002LevobupivacaineCytochrome P450 1A2enzyme
DB01009KetoprofenProstaglandin G/H synthase 1target
DB01009KetoprofenProstaglandin G/H synthase 2target
DB01009KetoprofenC-X-C chemokine receptor type 1target
DB01009KetoprofenSerum albumincarrier
DB01009KetoprofenMultidrug resistance-associated protein 4transporter
DB01009KetoprofenSolute carrier organic anion transporter family member 1A2transporter
DB01009KetoprofenSolute carrier family 22 member 6transporter
DB01009KetoprofenSolute carrier family 22 member 8transporter
DB01009KetoprofenSolute carrier family 22 member 11transporter
DB01009KetoprofenSolute carrier family 22 member 7transporter
DB01009KetoprofenCytochrome P450 2C9enzyme
DB01009KetoprofenCytochrome P450 2C8enzyme
DB01009KetoprofenUDP-glucuronosyltransferase 1-1enzyme
DB01014BalsalazideProstaglandin G/H synthase 1target
DB01014BalsalazideProstaglandin G/H synthase 2target
DB01014BalsalazideArachidonate 5-lipoxygenasetarget
DB01014BalsalazidePeroxisome proliferator-activated receptor gammatarget
DB01014BalsalazideNADPH azoreductaseenzyme
DB01028MethoxyfluraneCalcium-transporting ATPase type 2C member 1target
DB01028MethoxyfluraneATP synthase subunit delta, mitochondrialtarget
DB01028MethoxyfluraneNADH-ubiquinone oxidoreductase chain 1target
DB01028MethoxyfluraneGamma-aminobutyric acid receptor subunit alpha-1target
DB01028MethoxyfluranePotassium voltage-gated channel subfamily A member 1target
DB01028MethoxyfluraneGlutamate receptor 1target
DB01028MethoxyfluraneGlycine receptor subunit alpha-1target
DB01028MethoxyfluraneCytochrome P450 2E1enzyme
DB01028MethoxyfluraneCytochrome P450 1A2enzyme
DB01028MethoxyfluraneCytochrome P450 2A6enzyme
DB01028MethoxyfluraneCytochrome P450 2B6enzyme
DB01028MethoxyfluraneCytochrome P450 2C9enzyme
DB01028MethoxyfluraneCytochrome P450 2D6enzyme
DB01028MethoxyfluraneCytochrome P450 3A4enzyme
DB01028MethoxyfluraneGABA-A receptor (anion channel)target
DB01037SelegilineAmine oxidase [flavin-containing] Btarget
DB01037SelegilineCytochrome P450 2B6enzyme
DB01037SelegilineAmine oxidase [flavin-containing] Atarget
DB01037SelegilineCytochrome P450 2A6enzyme
DB01037SelegilineCytochrome P450 3A4enzyme
DB01037SelegilineMultidrug resistance protein 1transporter
DB01037SelegilineCytochrome P450 1A2enzyme
DB01037SelegilineCytochrome P450 2C19enzyme
DB01037SelegilineCytochrome P450 2C8enzyme
DB01037SelegilineCytochrome P450 2C9enzyme
DB01037SelegilineCytochrome P450 2D6enzyme
DB01037SelegilineCytochrome P450 2E1enzyme
DB01043MemantineCytochrome P450 2B6enzyme
DB01043MemantineSolute carrier family 22 member 2transporter
DB01043Memantine5-hydroxytryptamine receptor 3Atarget
DB01043MemantineAlpha-7 nicotinic cholinergic receptor subunittarget
DB01043MemantineCytochrome P450 2A6enzyme
DB01043MemantineCytochrome P450 2C19enzyme
DB01043MemantineD(2) dopamine receptortarget
DB01043MemantineGlutamate receptor ionotropic, NMDA 1target
DB01043MemantineSodium/hydrogen exchanger 1transporter
DB01043MemantineSolute carrier family 22 member 4transporter
DB01043MemantineMultidrug and toxin extrusion protein 1transporter
DB01043MemantineGlutamate (NMDA) receptortarget
DB01043MemantineGABA-A receptor (anion channel)target
DB01043MemantineGlycine receptorstarget
DB01049Ergoloid mesylateDopamine receptortarget
DB01049Ergoloid mesylateAlpha adrenergic receptortarget
DB01049Ergoloid mesylateBeta adrenergic receptortarget
DB01049Ergoloid mesylateSerotonin Receptorstarget
DB01049Ergoloid mesylateCytochrome P450 3A4enzyme
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenMultidrug resistance protein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01065MelatoninAcetylserotonin O-methyltransferasetarget
DB01065MelatoninMelatonin receptor type 1Atarget
DB01065MelatoninMelatonin receptor type 1Btarget
DB01065MelatoninNuclear receptor ROR-betatarget
DB01065MelatoninRibosyldihydronicotinamide dehydrogenase [quinone]target
DB01065MelatoninEstrogen receptor alphatarget
DB01065MelatoninEosinophil peroxidasetarget
DB01065MelatoninCytochrome P450 1A1enzyme
DB01065MelatoninCytochrome P450 1A2enzyme
DB01065MelatoninCytochrome P450 2C19enzyme
DB01065MelatoninCytochrome P450 2C9enzyme
DB01065MelatoninAcetylserotonin O-methyltransferaseenzyme
DB01065MelatoninIndoleamine 2,3-dioxygenase 1enzyme
DB01065MelatoninCytochrome P450 1B1enzyme
DB01065MelatoninSolute carrier family 22 member 8transporter
DB01065MelatoninCytochrome P450 19A1enzyme
DB01068ClonazepamTranslocator proteintarget
DB01068ClonazepamCytochrome P450 3A4enzyme
DB01068ClonazepamSerum albumincarrier
DB01068ClonazepamCytochrome P450 2E1enzyme
DB01068ClonazepamArylamine N-acetyltransferase 2enzyme
DB01068ClonazepamGABA-A receptor (anion channel)target
DB01068ClonazepamNuclear receptor subfamily 1 group I member 2target
DB01075DiphenhydramineHistamine H1 receptortarget
DB01075DiphenhydramineCytochrome P450 2D6enzyme
DB01075DiphenhydramineCytochrome P450 2C9enzyme
DB01075DiphenhydramineCytochrome P450 2C19enzyme
DB01075DiphenhydramineCytochrome P450 2C18enzyme
DB01075DiphenhydramineSolute carrier family 22 member 2transporter
DB01075DiphenhydramineSolute carrier family 22 member 5transporter
DB01075DiphenhydramineProstaglandin G/H synthase 1enzyme
DB01075DiphenhydramineMuscarinic acetylcholine receptor M2target
DB01080Vigabatrin4-aminobutyrate aminotransferase, mitochondrialtarget
DB01080VigabatrinGamma-aminobutyric acid type B receptor subunit 1target
DB01080VigabatrinProton-coupled amino acid transporter 1transporter
DB01080VigabatrinCytochrome P450 2C9enzyme
DB01081DiphenoxylateMu-type opioid receptortarget
DB01081DiphenoxylateDelta-type opioid receptortarget
DB01083OrlistatPancreatic triacylglycerol lipasetarget
DB01083OrlistatFatty acid synthasetarget
DB01083OrlistatGastric triacylglycerol lipasetarget
DB01083OrlistatCytochrome P450 3A4enzyme
DB01083OrlistatCytosolic phospholipase A2enzyme
DB01086BenzocaineSodium channel protein type 10 subunit alphatarget
DB01086BenzocaineMultidrug resistance protein 1transporter
DB01086BenzocaineLiver carboxylesterase 1enzyme
DB01100PimozideD(2) dopamine receptortarget
DB01100PimozidePotassium voltage-gated channel subfamily H member 2target
DB01100PimozideCytochrome P450 3A4enzyme
DB01100PimozideCytochrome P450 1A2enzyme
DB01100PimozideCytochrome P450 3A5enzyme
DB01100PimozideCytochrome P450 3A7enzyme
DB01100PimozideMultidrug resistance protein 1transporter
DB01100PimozideD(3) dopamine receptortarget
DB01100PimozideCytochrome P450 2D6enzyme
DB01100PimozideCytochrome P450 2E1enzyme
DB01104SertralineSodium-dependent serotonin transportertarget
DB01104SertralineCytochrome P450 2B6enzyme
DB01104SertralineCytochrome P450 2C19enzyme
DB01104SertralineCytochrome P450 2C9enzyme
DB01104SertralineCytochrome P450 2D6enzyme
DB01104SertralineSodium-dependent dopamine transportertarget
DB01104SertralineCYP2B proteinenzyme
DB01104SertralineCytochrome P450 3A4enzyme
DB01104SertralineAmine oxidase [flavin-containing] Benzyme
DB01104SertralineAmine oxidase [flavin-containing] Aenzyme
DB01104SertralineMultidrug resistance protein 1transporter
DB01104SertralineSerum albumincarrier
DB01104SertralineSigma receptortarget
DB01105SibutramineSodium-dependent serotonin transportertarget
DB01105SibutramineSodium-dependent noradrenaline transportertarget
DB01105SibutramineCytochrome P450 3A4enzyme
DB01105SibutramineSodium-dependent dopamine transportertarget
DB01116TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
DB01142DoxepinSodium-dependent serotonin transportertarget
DB01142DoxepinSodium-dependent noradrenaline transportertarget
DB01142DoxepinHistamine H1 receptortarget
DB01142DoxepinHistamine H2 receptortarget
DB01142DoxepinCytochrome P450 2D6enzyme
DB01142DoxepinMuscarinic acetylcholine receptor M1target
DB01142DoxepinMuscarinic acetylcholine receptor M2target
DB01142DoxepinMuscarinic acetylcholine receptor M3target
DB01142DoxepinMuscarinic acetylcholine receptor M4target
DB01142DoxepinMuscarinic acetylcholine receptor M5target
DB01142DoxepinAlpha-1A adrenergic receptortarget
DB01142Doxepin5-hydroxytryptamine receptor 1Atarget
DB01142Doxepin5-hydroxytryptamine receptor 2Atarget
DB01142DoxepinCytochrome P450 2C19enzyme
DB01142DoxepinCytochrome P450 2C9enzyme
DB01142DoxepinCytochrome P450 1A2enzyme
DB01142DoxepinMultidrug resistance protein 1transporter
DB01142Doxepin5-hydroxytryptamine receptor 2Btarget
DB01142Doxepin5-hydroxytryptamine receptor 2Ctarget
DB01142DoxepinAlpha-1B adrenergic receptortarget
DB01142DoxepinAlpha-1D adrenergic receptortarget
DB01142DoxepinCytochrome P450 3A4enzyme
DB01142Doxepin5-hydroxytryptamine receptor 6target
DB01142DoxepinHistamine H4 receptortarget
DB01142DoxepinPotassium voltage-gated channel subfamily H member 2target
DB01142DoxepinSerum albumincarrier
DB01142DoxepinAlpha-1-acid glycoprotein 1carrier
DB01149Nefazodone5-hydroxytryptamine receptor 2Atarget
DB01149NefazodoneSodium-dependent serotonin transportertarget
DB01149NefazodoneSodium-dependent noradrenaline transportertarget
DB01149NefazodoneAlpha-1A adrenergic receptortarget
DB01149NefazodoneAlpha-1B adrenergic receptortarget
DB01149NefazodoneCytochrome P450 3A4enzyme
DB01149NefazodoneCytochrome P450 2D6enzyme
DB01149NefazodoneSodium-dependent dopamine transportertarget
DB01149NefazodoneAlpha-2A adrenergic receptortarget
DB01149Nefazodone5-hydroxytryptamine receptor 1Atarget
DB01149NefazodoneCYP2B proteinenzyme
DB01149NefazodoneCytochrome P450 3A5enzyme
DB01149NefazodoneMultidrug resistance protein 1transporter
DB01149Nefazodone5-hydroxytryptamine receptor 2Ctarget
DB01149NefazodonePotassium voltage-gated channel subfamily H member 2target
DB01149NefazodoneSolute carrier organic anion transporter family member 1B3transporter
DB01149NefazodoneSolute carrier organic anion transporter family member 2B1transporter
DB01149NefazodoneBile salt export pumptransporter
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineMultidrug resistance protein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2A6enzyme
DB01151DesipramineCytochrome P450 2C18enzyme
DB01151DesipramineCytochrome P450 2C19enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineD(2) dopamine receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB01154ThiamylalGamma-aminobutyric acid receptor subunit alpha-1target
DB01154ThiamylalATP-sensitive inward rectifier potassium channel 8target
DB01154ThiamylalATP-sensitive inward rectifier potassium channel 11target
DB01154ThiamylalCytochrome P450 2C9enzyme
DB01154ThiamylalCytochrome P450 3A4enzyme
DB01154ThiamylalCytochrome P450 2E1enzyme
DB01156BupropionSodium-dependent dopamine transportertarget
DB01156BupropionSodium-dependent noradrenaline transportertarget
DB01156BupropionCytochrome P450 2B6enzyme
DB01156BupropionCytochrome P450 2D6enzyme
DB01156BupropionAlpha-1-acid glycoprotein 1carrier
DB01156BupropionNeuronal acetylcholine receptor subunit alpha-3target
DB01156BupropionCytochrome P450 2A6enzyme
DB01156BupropionCytochrome P450 2C8enzyme
DB01156BupropionCytochrome P450 2C9enzyme
DB01156BupropionCytochrome P450 2E1enzyme
DB01156BupropionCytochrome P450 3A4enzyme
DB01156BupropionSolute carrier family 22 member 2transporter
DB01159HalothaneGamma-aminobutyric acid receptor subunit alpha-1target
DB01159HalothaneGlycine receptor subunit alpha-1target
DB01159HalothaneCalcium-activated potassium channel subunit alpha-1target
DB01159HalothaneCalcium-transporting ATPase type 2C member 1target
DB01159HalothaneNADH-ubiquinone oxidoreductase chain 1target
DB01159HalothaneIntermediate conductance calcium-activated potassium channel protein 4target
DB01159HalothaneATP synthase subunit delta, mitochondrialtarget
DB01159HalothaneG protein-activated inward rectifier potassium channel 2target
DB01159HalothaneG protein-activated inward rectifier potassium channel 1target
DB01159HalothaneGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2target
DB01159HalothaneNeuropeptide S receptortarget
DB01159HalothaneCytochrome P450 2E1enzyme
DB01159HalothaneCytochrome P450 2A6enzyme
DB01159HalothaneCytochrome P450 3A4enzyme
DB01159HalothaneGlutamate receptor ionotropic, NMDA 3Atarget
DB01159HalothaneGlutamate receptor ionotropic, NMDA 3Btarget
DB01159HalothaneGlutamate receptor ionotropic, NMDA 2Atarget
DB01159HalothanePotassium channel subfamily K member 3target
DB01159HalothanePotassium channel subfamily K member 9target
DB01159HalothaneSerum albumincarrier
DB01159HalothaneCytochrome P450 2B6enzyme
DB01159HalothaneCytochrome P450 2C9enzyme
DB01159HalothaneGABA-A receptor (anion channel)target
DB01161ChloroprocaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineNeuronal acetylcholine receptor subunit alpha-10target
DB01161ChloroprocaineSodium-dependent dopamine transportertarget
DB01161ChloroprocaineGlutamate receptor ionotropic, NMDA 3Atarget
DB01161Chloroprocaine5-hydroxytryptamine receptor 3Atarget
DB01166CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01166CilostazolCytochrome P450 2C19enzyme
DB01166CilostazolCytochrome P450 3A4enzyme
DB01166CilostazolCytochrome P450 3A5enzyme
DB01166CilostazolCytochrome P450 3A7enzyme
DB01166CilostazolCytochrome P450 1A2enzyme
DB01166CilostazolCytochrome P450 2D6enzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Atarget
DB01171MoclobemideCytochrome P450 2C19enzyme
DB01171MoclobemideCytochrome P450 2D6enzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Aenzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Benzyme
DB01171MoclobemideCytochrome P450 2C9enzyme
DB01171MoclobemideMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 1target
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
DB01173OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
DB01173OrphenadrineHistamine H1 receptortarget
DB01173OrphenadrineCytochrome P450 2B6enzyme
DB01173OrphenadrineCytochrome P450 2E1enzyme
DB01173OrphenadrineCytochrome P450 3A4enzyme
DB01173OrphenadrineSodium-dependent noradrenaline transportertarget
DB01173OrphenadrineSodium channel protein type 10 subunit alphatarget
DB01173OrphenadrineCytochrome P450 1A2enzyme
DB01174PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
DB01174PhenobarbitalCytochrome P450 2C19enzyme
DB01174PhenobarbitalCytochrome P450 2C9enzyme
DB01174PhenobarbitalCytochrome P450 2B6enzyme
DB01174PhenobarbitalCytochrome P450 2C8enzyme
DB01174PhenobarbitalCytochrome P450 1A2enzyme
DB01174PhenobarbitalCytochrome P450 3A4enzyme
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
DB01174PhenobarbitalBile salt export pumptransporter
DB01174PhenobarbitalMultidrug resistance protein 1transporter
DB01174PhenobarbitalMultidrug resistance-associated protein 1transporter
DB01174PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
DB01174PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
DB01174PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
DB01174PhenobarbitalGlutamate receptor 2target
DB01174PhenobarbitalGlutamate receptor ionotropic, kainate 2target
DB01174PhenobarbitalCytochrome P450 2A6enzyme
DB01174PhenobarbitalCytochrome P450 2E1enzyme
DB01174PhenobarbitalCytochrome P450 3A5enzyme
DB01174PhenobarbitalCytochrome P450 4A11enzyme
DB01174PhenobarbitalCytochrome P450 1A1enzyme
DB01174PhenobarbitalCytochrome P450 1B1enzyme
DB01174PhenobarbitalCytochrome P450 2C18enzyme
DB01174PhenobarbitalCytochrome P450 3A7enzyme
DB01174PhenobarbitalCytochrome P450 4B1enzyme
DB01174PhenobarbitalNMDA receptortarget
DB01174PhenobarbitalNuclear receptor subfamily 1 group I member 2target
DB01174PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
DB01174PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
DB01175EscitalopramSodium-dependent serotonin transportertarget
DB01175EscitalopramCytochrome P450 3A4enzyme
DB01175EscitalopramCytochrome P450 2D6enzyme
DB01175EscitalopramSodium-dependent dopamine transportertarget
DB01175EscitalopramSodium-dependent noradrenaline transportertarget
DB01175EscitalopramAlpha-1A adrenergic receptortarget
DB01175EscitalopramMuscarinic acetylcholine receptor M1target
DB01175EscitalopramHistamine H1 receptortarget
DB01175EscitalopramCytochrome P450 2C19enzyme
DB01176CyclizineHistamine H1 receptortarget
DB01176CyclizineEstrogen sulfotransferasetarget
DB01176CyclizineCytochrome P450 2C9enzyme
DB01178ChlormezanoneTranslocator proteintarget
DB01183NaloxoneMu-type opioid receptortarget
DB01183NaloxoneEstrogen receptor alphatarget
DB01183NaloxoneCyclic AMP-responsive element-binding protein 1target
DB01183NaloxoneDelta-type opioid receptortarget
DB01183NaloxoneSolute carrier organic anion transporter family member 1A2transporter
DB01183NaloxoneMultidrug resistance protein 1transporter
DB01183NaloxoneKappa-type opioid receptortarget
DB01183NaloxoneCytochrome P450 2C8enzyme
DB01183NaloxoneCytochrome P450 3A4enzyme
DB01183NaloxoneSerum albumincarrier
DB01183NaloxoneToll-like receptor 4target
DB01183NaloxoneLiver carboxylesterase 1target
DB01183NaloxoneUDP-glucuronosyltransferase 1-1enzyme
DB01184DomperidoneD(2) dopamine receptortarget
DB01184DomperidoneCytochrome P450 3A4enzyme
DB01184DomperidoneCytochrome P450 3A5enzyme
DB01184DomperidoneCytochrome P450 3A7enzyme
DB01184DomperidoneMultidrug resistance protein 1transporter
DB01184DomperidoneCytochrome P450 1A2enzyme
DB01184DomperidoneCytochrome P450 2B6enzyme
DB01184DomperidoneCytochrome P450 2C8enzyme
DB01184DomperidoneCytochrome P450 2D6enzyme
DB01184DomperidoneD(3) dopamine receptortarget
DB01189DesfluraneCalcium-transporting ATPase type 2C member 1target
DB01189DesfluraneNADH-ubiquinone oxidoreductase chain 1target
DB01189DesfluraneGlycine receptor subunit alpha-1target
DB01189DesfluraneGlutamate receptor 1target
DB01189DesfluraneGABA-A receptor (anion channel)target
DB01189DesfluranePotassium voltage-gated channel subfamily A member 1target
DB01189DesfluraneATP synthase subunit delta, mitochondrialtarget
DB01189DesfluraneSerum albumincarrier
DB01192OxymorphoneMu-type opioid receptortarget
DB01192OxymorphoneCytochrome P450 2D6enzyme
DB01192OxymorphoneDelta-type opioid receptortarget
DB01192OxymorphoneCytochrome P450 3A4enzyme
DB01198ZopicloneTranslocator proteintarget
DB01198ZopicloneCytochrome P450 2C8enzyme
DB01198ZopicloneCytochrome P450 2C9enzyme
DB01198ZopicloneCytochrome P450 3A4enzyme
DB01198ZopicloneProstaglandin G/H synthase 1enzyme
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-1target
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-2target
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-3target
DB01198ZopicloneGamma-aminobutyric acid receptor subunit alpha-5target
DB01198ZopicloneCytochrome P450 2E1enzyme
DB01200BromocriptineD(2) dopamine receptortarget
DB01200BromocriptineCytochrome P450 3A4enzyme
DB01200Bromocriptine5-hydroxytryptamine receptor 1Dtarget
DB01200BromocriptineAlpha-2A adrenergic receptortarget
DB01200BromocriptineD(3) dopamine receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Atarget
DB01200BromocriptineAlpha-2C adrenergic receptortarget
DB01200BromocriptineAlpha-2B adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Btarget
DB01200BromocriptineD(4) dopamine receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Atarget
DB01200Bromocriptine5-hydroxytryptamine receptor 1Btarget
DB01200Bromocriptine5-hydroxytryptamine receptor 2Ctarget
DB01200BromocriptineD(1B) dopamine receptortarget
DB01200BromocriptineD(1A) dopamine receptortarget
DB01200BromocriptineAlpha-1A adrenergic receptortarget
DB01200BromocriptineAlpha-1B adrenergic receptortarget
DB01200BromocriptineAlpha-1D adrenergic receptortarget
DB01200Bromocriptine5-hydroxytryptamine receptor 7target
DB01200BromocriptineMultidrug resistance protein 1transporter
DB01202LevetiracetamSynaptic vesicle glycoprotein 2Atarget
DB01202LevetiracetamMultidrug resistance protein 1transporter
DB01202LevetiracetamCanalicular multispecific organic anion transporter 1transporter
DB01202LevetiracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB01202LevetiracetamCytochrome P450 3A4enzyme
DB01204MitoxantroneDNA topoisomerase 2-alphatarget
DB01204MitoxantroneCytochrome P450 2E1enzyme
DB01204MitoxantroneMultidrug resistance protein 1transporter
DB01204MitoxantroneMultidrug resistance-associated protein 1transporter
DB01204MitoxantroneATP-binding cassette sub-family G member 2transporter
DB01204MitoxantroneCytochrome P450 1B1enzyme
DB01204MitoxantroneCytochrome P450 3A4enzyme
DB01209DezocineMu-type opioid receptortarget
DB01209DezocineKappa-type opioid receptortarget
DB01215EstazolamCytochrome P450 3A4enzyme
DB01215EstazolamGamma-aminobutyric acid receptor subunit alpha-1target
DB01215EstazolamGamma-aminobutyric acid receptor subunit alpha-2target
DB01215EstazolamGamma-aminobutyric acid receptor subunit alpha-3target
DB01215EstazolamGamma-aminobutyric acid receptor subunit alpha-5target
DB01215EstazolamGamma-aminobutyric acid receptor subunit gamma-1target
DB01215EstazolamGamma-aminobutyric acid receptor subunit gamma-2target
DB01215EstazolamGamma-aminobutyric acid receptor subunit gamma-3target
DB01215EstazolamGamma-aminobutyric acid receptor subunit beta-1target
DB01215EstazolamGamma-aminobutyric acid receptor subunit beta-2target
DB01215EstazolamGamma-aminobutyric acid receptor subunit beta-3target
DB01215EstazolamGamma-aminobutyric acid receptor subunit deltatarget
DB01215EstazolamGamma-aminobutyric acid receptor subunit epsilontarget
DB01215EstazolamGamma-aminobutyric acid receptor subunit pitarget
DB01215EstazolamGamma-aminobutyric acid receptor subunit rho-1target
DB01215EstazolamGamma-aminobutyric acid receptor subunit rho-2target
DB01215EstazolamGamma-aminobutyric acid receptor subunit rho-3target
DB01215EstazolamGABA-A receptor (anion channel)target
DB01219DantroleneRyanodine receptor 1target
DB01219DantroleneCytochrome P450 3A4enzyme
DB01219DantroleneThyroxine-binding globulincarrier
DB01221KetamineGlutamate receptor ionotropic, NMDA 3Atarget
DB01221KetamineSubstance-P receptortarget
DB01221KetamineCytochrome P450 2B6enzyme
DB01221KetamineCytochrome P450 2C9enzyme
DB01221KetamineCytochrome P450 3A4enzyme
DB01221KetamineD(2) dopamine receptortarget
DB01221KetamineProstaglandin G/H synthase 1enzyme
DB01221KetamineCytochrome P450 2C8enzyme
DB01221KetamineDelta-type opioid receptortarget
DB01221KetamineSodium-dependent noradrenaline transportertarget
DB01221KetamineKappa-type opioid receptortarget
DB01221KetamineMu-type opioid receptortarget
DB01221KetamineMuscarinic acetylcholine receptortarget
DB01221Ketamine5-hydroxytryptamine receptor 2target
DB01221Ketamine5-hydroxytryptamine receptor 1target
DB01221Ketamine5-hydroxytryptamine receptor 3Atarget
DB01221KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
DB01221KetamineNitric oxide synthase, braintarget
DB01224Quetiapine5-hydroxytryptamine receptor 2Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 2Ctarget
DB01224QuetiapineD(2) dopamine receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Atarget
DB01224QuetiapineHistamine H1 receptortarget
DB01224QuetiapineCytochrome P450 3A4enzyme
DB01224QuetiapineAlpha-1A adrenergic receptortarget
DB01224QuetiapineAlpha-1B adrenergic receptortarget
DB01224QuetiapineAlpha-1D adrenergic receptortarget
DB01224QuetiapineAlpha-2A adrenergic receptortarget