Minor burns

Also known as: Burn / Burns / This code is not for inpatient use. Code to specified site and degree of burns / Burn of unspecified site, unspecified degree / Burns NOS / Thermal burns / Thermal burn

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
DB00479AmikacinAmikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A.[A39531] Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and Pseudomonas aeruginosa. Amikacin also exerts excellent activity against most aerobic gram-negative bacilli from the Enterobacteriaceae family, including Nocardia and some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. M. avium-intracellulare (MAC) is a type of nontuberculous mycobacteria (NTM) found in water and soil. Symptoms of this disease include a persistent cough, fatigue, weight loss, night sweats, and shortness of breath and the coughing up of blood.[L4680] Several forms of amikacin are used currently, including an intravenous (IV) or intramuscular (IM) injection.[F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population of patients with the disease who do not respond to traditional treatment.[L4680,L4681]
DB13501BendazacBendazac is an oxyacetic acid [A39863, A39869]. Despite possessing anti-inflammatory, anti-necrotic, choleretic, and anti-lipidemic characteristics, most research has revolved around studying and demonstrating the agent's principal action in inhibiting the denaturation of proteins - an effect that has primarily proven useful in managing and delaying the progression of ocular cataracts [A39863. A39863]. Bendazac, however, has since been withdrawn or discontinued in various international regions due to its capability or risk for eliciting hepatotoxicity [A39891, A39892, A39893, L4778] in patients although a small handful of regions may continue to have the medication available for purchase and use either as a topical anti-inflammatory/analgesic cream or eye drop formulation.
DB01744CamphorA bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent.
DB00048Collagenase clostridium histolyticumCollagenase clostridium histolyticum is an enzyme produced by the bacterium _Clostridium histolyticum_ that dismantles collagen. It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis. BioSpecifics Technologies developed the preparation, which is manufactured and marketed by Auxilium Pharmaceuticals as Xiaflex in the US and by Sobi as Xiapex in Europe.
DB00062Human Serum AlbuminHuman serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood [A33706]. It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately 50% of the total protein content in healthy humans [A40060]. Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain of 585 amino acids organized in three repeated homolog domains (sites I, II, and III). Each domain comprises two separate sub-domains (A and B) [A40060]. There are various preparations of albumin that are well established and widely available in the clinical setting [L3108], [L3109], [L3101]. Also known as _Albuminex_ 5% or 25%, one brand of human serum albumin is prepared from the pooled plasma of US donors in FDA-licensed facilities in the US [F229]. This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101].
DB14112Human vaccinia virus immune globulinHuman vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent/detergent-treated to sterilize the compound [A33814]. Most compounds used currently are intravenous formulations, which contain no preservatives - unlike prior intramuscular compounds which contained thiomersal, a mercury derivative preservative that could be potentially teratogenic [A33814]. Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human product that is only available in very limited quantities - all factors that may intervene with its availability and effectiveness [A33798, A33814].
DB09449Sodium phosphate, monobasicSodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidMultidrug resistance protein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidNuclear factor kappa b beta subunittarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00479Amikacin30S ribosomal protein S12target
DB13501BendazacFree radicalstarget
DB13501BendazacProstaglandin G/H synthase 1target
DB13501BendazacProstaglandin G/H synthase 2target
DB01744CamphorCamphor 5-monooxygenasetarget
DB01744CamphorTransient receptor potential cation channel subfamily V member 1target
DB01744CamphorTransient receptor potential cation channel subfamily V member 3target
DB01744CamphorTransient receptor potential cation channel subfamily A member 1target
DB01744CamphorTransient receptor potential cation channel subfamily M member 8target
DB00048Collagenase clostridium histolyticumCollagen alpha-1(I) chaintarget
DB00048Collagenase clostridium histolyticumCollagen alpha-1(II) chaintarget
DB00048Collagenase clostridium histolyticumCollagen alpha-1(III) chaintarget
DB00048Collagenase clostridium histolyticumCollagen alpha-2(I) chaintarget
DB00062Human Serum AlbuminNitric oxidetarget
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transporter 1transporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transporter 2transporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transport protein 2Atransporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transport protein 2Btransporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transport protein 2Ctransporter
DrugDrug NamePhaseStatusCount
DB00297Bupivacaine0Not Yet Recruiting1
DB11079Trolamine salicylate1Recruiting1
DB00633Dexmedetomidine1 / 2Recruiting1
DB00684Tobramycin1 / 2Completed1
DB05245Silver sulfadiazine2Completed1
DB00626Bacitracin2 / 3Withdrawn1
DB11121Chloroxylenol2 / 3Active Not Recruiting2
DB11121Chloroxylenol2 / 3Recruiting3
DB00575Clonidine2 / 3Completed1
DB01276Exenatide2 / 3Completed1
DB01039Fenofibrate2 / 3Completed1
DB01039Fenofibrate2 / 3Recruiting1
DB01039Fenofibrate2 / 3Withdrawn1
DB00196Fluconazole2 / 3Completed1
DB00196Fluconazole2 / 3Recruiting1
DB01109Heparin2 / 3Withdrawn1
DB01167Itraconazole2 / 3Completed1
DB01167Itraconazole2 / 3Recruiting1
DB01026Ketoconazole2 / 3Completed1
DB01026Ketoconazole2 / 3Recruiting1
DB06795Mafenide2 / 3Terminated1
DB01277Mecasermin2 / 3Completed1
DB00331Metformin2 / 3Completed1
DB00264Metoprolol2 / 3Active Not Recruiting1
DB00264Metoprolol2 / 3Recruiting3
DB00646Nystatin2 / 3Withdrawn1
DB00621Oxandrolone2 / 3Completed1
DB00621Oxandrolone2 / 3Recruiting1
DB00082Pegvisomant2 / 3Active Not Recruiting1
DB00082Pegvisomant2 / 3Completed1
DB00082Pegvisomant2 / 3Recruiting1
DB01132Pioglitazone2 / 3Completed1
DB00781Polymyxin B2 / 3Withdrawn1
DB05804Prasterone sulfate2 / 3Completed1
DB00571Propranolol2 / 3Active Not Recruiting1
DB00571Propranolol2 / 3Completed1
DB00571Propranolol2 / 3Recruiting3
DB11080Silver nitrate2 / 3Terminated1
DB00052Somatotropin2 / 3Active Not Recruiting1
DB06417Somatotropin2 / 3Completed1
DB00052Somatotropin2 / 3Recruiting1
DB06417Somatotropin2 / 3Recruiting1
DB00624Testosterone2 / 3Completed1
DB00624Testosterone2 / 3Recruiting1
DB00759Tetracycline2 / 3Terminated1
DB11300Thrombin2 / 3Withdrawn1
DB00163Vitamin E2 / 3Completed1
DB00036Coagulation factor VIIa Recombinant Human3Completed1
DB00986Glycopyrronium3Active Not Recruiting1
DB00105Interferon alfa-2b3Withdrawn1
DB01400Neostigmine3Active Not Recruiting1
DB06206Sugammadex3Active Not Recruiting1
DB11094Vitamin D3Withdrawn1
DB00062Human Serum Albumin4Terminated1
DB09106Hydroxyethyl Starch4Terminated1
DB01022Phylloquinone4Not Yet Recruiting1
DB05245Silver sulfadiazine4Completed1
DB09153Sodium chloride4Active Not Recruiting1
DB09153Sodium chloride4Recruiting2
DB00302Tranexamic acid4Recruiting1
DB00126Ascorbic acidNot AvailableWithdrawn1
DB00626BacitracinNot AvailableWithdrawn1
DB11121ChloroxylenolNot AvailableRecruiting1
DB09341Dextrose, unspecified formNot AvailableCompleted1
DB00668EpinephrineNot AvailableCompleted1
DB09222Fibrinogen HumanNot AvailableCompleted1
DB11571Human ThrombinNot AvailableCompleted1
DB09374Indocyanine green acid formNot AvailableCompleted1
DB00030Insulin HumanNot AvailableRecruiting1
DB00130L-GlutamineNot AvailableWithdrawn1
DB00281LidocaineNot AvailableCompleted1
DB06795MafenideNot AvailableCompleted1
DB00331MetforminNot AvailableRecruiting1
DB00295MorphineNot AvailableWithdrawn1
DB00994NeomycinNot AvailableCompleted1
DB00994NeomycinNot AvailableWithdrawn1
DB00571PropranololNot AvailableRecruiting1
DB05245Silver sulfadiazineNot AvailableCompleted2
DB00624TestosteroneNot AvailableUnknown Status1
DB00302Tranexamic acidNot AvailableRecruiting1