Chronic Alcoholism

Also known as: Chronic alcohol abuse / Alcohol addiction / Alcohol abuse chronic / Alcohol dependence / Alcoholism / Dipsomania / Alcohol abuse, continuous drinking behaviour / Alcohol abuse, continuous drinking behavior / Alcohol dependence syndrome

DrugDrug NameDrug Description
DB00822DisulfiramA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
DrugDrug NamePhaseStatusCount
DB00683MidazolamNot AvailableTerminated1