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Displaying drugs 1 - 25 of 35 in total

Bacillus calmette-guerin substrain connaught live antigen

Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder and for the prophylaxis of primary or recurrent stage Ta and/or T1 papillary tumors following transurethral resection (TUR). The solution contains live, attenuated strain of Mycobacterium bovis....
Approved
Investigational
Matched Name: … Bacillus calmette-guerin substrain connaught live antigen …
Matched Description: … It is prepared from the Connaught strain of Bacillus Calmette and Guérin. ... Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment …
Matched Categories: … Live Attenuated Bacillus Calmette-Guerin Vaccine ... Live Attenuated Bacillus Calmette-Guerin Immunotherapy …

Bacillus calmette-guerin substrain tice live antigen

Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis for percutaneous use. It is administered to prevent the development of tuberculosis.
Approved
Matched Name: … Bacillus calmette-guerin substrain tice live antigen …
Matched Description: … Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture ... preparation of the Bacillus of Calmette and Guerin (BCG) strain of *Mycobacterium bovis* for percutaneous …
Matched Categories: … Live Attenuated Bacillus Calmette-Guerin Vaccine ... Live Attenuated Bacillus Calmette-Guerin Immunotherapy …

Anthrax vaccine

Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Synonyms: … Bacillus anthracis inactivated antigen ... Bacillus anthracis strain V770-NP1-R antigen ... Bacillus anthracis strain V770-NP1-R antigens …
Matched Description: … post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to *Bacillus ... derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus …
Matched Categories: … Live Attenuated Bacillus Anthracis Vaccine …

Hexachlorophene

A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Approved
Withdrawn

Tyrothricin

Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus . This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely of the six predominant tyrocidines, TrcA/A1,...
Approved
Matched Description: … and Bacillus aneurinolyticus [A36353]. ... Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus ... Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis …

Bacitracin

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Description: … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the …

Tapinarof

Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Matched Description: … metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in _Photorhabdus luminescens_, a gram-negative bacillus …

Benzylpenicillin

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered...
Approved
Vet approved
Matched Description: … also be used as first or second line agents against susceptible gram positive aerobic bacilli such as *Bacillus …

Gramicidin D

Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis and called collectively gramicidin D. Gramcidins are 15 residue peptides with alternating D and L amino...
Approved
Matched Synonyms: … Bacillus brevis gramicidin D …
Matched Description: … , making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus …

Lactobacillus acidophilus

Approved
Experimental
Matched Synonyms: … Bacillus acidophilus whole …

Nadofaragene firadenovec

Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Description: … [L44381] It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin …

Raxibacumab

Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Approved

Pyrazinamide

A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational

Bacillus calmette-guerin substrain russian BCG-I live antigen

Bacillus Calmette-Guerin (BCG) substrain Russian BCG-I is a live BCG vaccine administered directly into the bladder for the adjuvant treatment of papillary urothelial cell carcinoma of the bladder. Live BCG vaccines administered intravesically have been a gold standard therapy in the adjuvant treatment of non-muscle-invasive bladder cancers for decades, used...
Approved
Matched Synonyms: … Bacillus Calmette-Guérin (BCG) - strain russian BCG-I …
Matched Name: … Bacillus calmette-guerin substrain russian BCG-I live antigen …
Matched Description: … Bacillus Calmette-Guerin (BCG) substrain Russian BCG-I is a live BCG vaccine administered directly into …

BCG vaccine

BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.
Approved
Investigational
Matched Synonyms: … Bacillus Calmette–Guérin (BCG) vaccine ... Bacillus calmette-guerin live antigen, unspecified substrain …
Matched Categories: … Live Attenuated Bacillus Calmette-Guerin Vaccine …

Clostridium tetani

Approved
Matched Synonyms: … Bacillus tetani whole …

Anthrax immune globulin human

Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified. Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing...
Approved
Matched Synonyms: … Bacillus anthracis immune globulin human …
Matched Description: … slow IV infusion containing polyclonal antibodies that bind the protective antigen (PA) component of Bacillus …

Eucalyptus oil

Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions....
Approved

Colistin

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … Cyclic polypeptide antibiotic from Bacillus colistinus. …

Clofazimine

Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin...
Approved
Investigational

Bacillus subtilis

Experimental
Matched Synonyms: … Bacillus subtilis whole …
Matched Name: … Bacillus subtilis …

Bacillus amyloliquefaciens

Experimental
Matched Synonyms: … Bacillus amyloliquefaciens ... Bacillus velezensis whole ... Bacillus amyloliquefaciens whole …
Matched Name: … Bacillus amyloliquefaciens …

Bacillus clausii

Experimental
Matched Name: … Bacillus clausii …

Bacillus calmette-guerin substrain danish 1331 live antigen

BCG SSI has been used in trials studying Tuberculosis.
Investigational
Matched Name: … Bacillus calmette-guerin substrain danish 1331 live antigen …
Matched Categories: … Live Attenuated Bacillus Calmette-Guerin Vaccine …

Bacillus calmette-guerin substrain tokyo 172-1 live antigen

Bacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial NCT03091660 (S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer).
Investigational
Matched Name: … Bacillus calmette-guerin substrain tokyo 172-1 live antigen …
Matched Description: … Bacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial …
Displaying drugs 1 - 25 of 35 in total