BCG vaccine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
BCG vaccine
Accession Number
DB12768
Type
Biotech
Groups
Investigational
Biologic Classification
Vaccines
Other vaccines
Description

BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.

Synonyms
  • Bacillus calmette-guerin live antigen, unspecified substrain
  • BCG
Categories
UNII
8VJE55B0VG
CAS number
Not Available

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
2-MethoxyethanolThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with 2-Methoxyethanol.
2-MethoxyethanolThe risk or severity of infection can be increased when BCG vaccine is combined with 2-Methoxyethanol.
6-Deoxyerythronolide BThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with 6-Deoxyerythronolide B.
9-(N-methyl-L-isoleucine)-cyclosporin AThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with 9-(N-methyl-L-isoleucine)-cyclosporin A.
9-(N-methyl-L-isoleucine)-cyclosporin AThe risk or severity of infection can be increased when BCG vaccine is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
AbataceptThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Abatacept.
AbataceptThe risk or severity of infection can be increased when BCG vaccine is combined with Abatacept.
AbetimusThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Abetimus.
AbetimusThe risk or severity of infection can be increased when BCG vaccine is combined with Abetimus.
Acetyl sulfisoxazoleThe therapeutic efficacy of BCG vaccine can be decreased when used in combination with Acetyl sulfisoxazole.
Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Substance
347911376
Wikipedia
BCG_vaccine
ATC Codes
L03AX03 — Bcg vaccine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0Active Not RecruitingBasic ScienceTuberculosis Infection1
0CompletedBasic ScienceTuberculosis Infection1
0CompletedTreatmentBladder Cancers1
1CompletedBasic ScienceTuberculosis Infection1
1CompletedPreventionHealthy Volunteers / Tuberculosis Infection1
1CompletedPreventionTuberculosis Infection7
1CompletedTreatmentBladder Cancers1
1CompletedTreatmentDiabetes, Diabetes Mellitus Type 11
1CompletedTreatmentUrinary Bladder Neoplasms1
1RecruitingOtherTuberculosis Infection1
1RecruitingTreatmentRecurrent Bladder Carcinoma / Stage 0a Bladder Urothelial Carcinoma / Stage 0is Bladder Urothelial Carcinoma / Stage I Bladder Cancer1
1TerminatedTreatmentMetastatic Melanoma1
1WithdrawnTreatmentBladder Cancers1
1, 2Active Not RecruitingTreatmentBladder Cancers1
1, 2Active Not RecruitingTreatmentNon-muscle Invasive Bladder Cancer (NMIBC)1
1, 2CompletedPreventionTuberculosis Infection1
1, 2CompletedTreatmentBladder Cancers1
1, 2Not Yet RecruitingPreventionTuberculosis Infection1
1, 2Not Yet RecruitingTreatmentImmunogenicity / Safety1
1, 2RecruitingTreatmentBladder Cancers / Transitional Cell Carcinoma1
1, 2TerminatedTreatmentMelanoma1
2Active Not RecruitingTreatmentBladder Cancers2
2Active Not RecruitingTreatmentBladder Cancers / High Risk Superficial1
2CompletedBasic ScienceHIV Exposure / Human Immunodeficiency Virus (HIV) Infections1
2CompletedDiagnosticTuberculosis Infection1
2CompletedPreventionImmunity, Cellular / Type IV hypersensitivity reaction1
2CompletedPreventionPlasmodium Infections1
2CompletedPreventionTuberculosis Infection3
2CompletedTreatmentPoisoning by BCG Vaccine1
2Not Yet RecruitingPreventionTuberculosis Infection1
2Not Yet RecruitingTreatmentEndoscopic Surgical Procedure / High Risk Superficial Upper Urinary Tract Transitional Cell Carcinoma / Transitional Epithelial Cells1
2Not Yet RecruitingTreatmentFibromyalgia1
2RecruitingTreatmentBladder Cancers1
2RecruitingTreatmentBladder Cancers / Bladder Tumors / Neoplasms, Bladder1
2Unknown StatusTreatmentBladder Cancers1
2, 3CompletedPreventionHealthy Volunteers2
2, 3CompletedPreventionInfluenza Virus Infection / Trained Immunity1
3Active Not RecruitingPreventionAllergies / Dermatitis, Eczematous / Respiratory Tract Infections (RTI)1
3CompletedDiagnosticTuberculosis Infection1
3CompletedPreventionPlasmodium Infections1
3Not Yet RecruitingTreatmentBladder Cancers1
3Not Yet RecruitingTreatmentHigh-risk Non-muscle Invasive Bladder Cancer1
3RecruitingTreatmentBladder Cancers2
3RecruitingTreatmentNon-muscle-invasive Bladder Cancer1
3RecruitingTreatmentStage 0 Bladder Urothelial Carcinoma / Stage 0is Bladder Urothelial Carcinoma / Stage I Bladder Urothelial Carcinoma1
3TerminatedTreatmentBladder Cancers1
3TerminatedTreatmentMalignant Tumor of Urinary Bladder / Neoplasms / Neoplasms by Site / Urinary Bladder Cancer / Urinary Bladder Diseases / Urinary Bladder Neoplasms / Urologic Diseases / Urologic Neoplasms1
3Unknown StatusTreatmentBladder Cancers1
3WithdrawnTreatmentBladder Cancers1
3WithdrawnTreatmentGenitourinary tract neoplasm / Neoplasms / Neoplasms by Site / Urinary Bladder Diseases / Urinary Bladder Neoplasms / Urologic Diseases / Urologic Neoplasms1
4CompletedPreventionTuberculosis Infection1
4RecruitingBasic ScienceBacille Calmette-Guérin / Innate Immunity1
4RecruitingPreventionHospitalization / Infection NOS / The Mortality Rate1
4TerminatedPreventionEarly Neonatal Mortality1
4TerminatedPreventionPlasmodium Infections1
Not AvailableActive Not RecruitingTreatmentBladder Cancers1
Not AvailableCompletedBasic ScienceBCG Vaccination1
Not AvailableCompletedPreventionAsthma Bronchial / Atopic Dermatitis (AD) / Food Allergy / Rhinitis1
Not AvailableCompletedPreventionTuberculosis Infection1
Not AvailableCompletedTreatmentTransitional Carcinoma of Urinary Bladder1
Not AvailableNot Yet RecruitingPreventionBCG Vaccination Reaction1
Not AvailableRecruitingBasic ScienceNewborn Vaccine Immunogenicity1
Not AvailableTerminatedBasic ScienceDiabetes Mellitus (DM) / Tuberculosis Infection1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Classification
Not classified

Drug created on October 20, 2016 18:07 / Updated on November 02, 2018 07:29