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Displaying drugs 1 - 25 of 389 in total
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Synonyms: … Nicotinamida ... Nicotinamide ... Nicotinamidum
Matched Name: … Nicotinamide
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and
Matched Mixtures name: … Ribotin-E ... Nicotinamide Zcf ... Nicotinamide
Matched Salts name: … Nicotinamide hydrochloride …
Matched Categories: … nicotinamide ... Alimentary Tract and Metabolism …
Matched Products: … NICOTINAMIDE ... NICOTINAMIDE IDI ... NICOTINAMIDE NOVASOREL …
Nicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and Mitochondrial Biogenesis).
Investigational
Matched Name: … Nicotinamide riboside
Matched Description: … Nicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Synonyms: … Nicotinamide dinucleotide ... Nicotinamide adenine dinucleotide ... Nicotinamide-adenine dinucleotide …
Matched Description: … electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet...
Investigational
Matched Synonyms: … (E)-resveratrol ... trans-resveratrol
Matched Name: … Resveratrol
Matched Description: … It exists as cis-(Z) and trans-(E) isomers. ... Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. ... It has been claimed that it is readily degraded by exposure to light, heat, and oxygen. …
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Synonyms: … trans-resveratrol 3-β-glucoside ... resveratrol-3-O-b-mono-D-glucoside ... trans-resveratrol 3-β-D-glucoside …
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. ... in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid nicotinamide complex ... Nicotinamide-ascorbic acid complex …
Matched Mixtures name: … Stress B Complex With C and E Tab ... Stress B Complex With C, E and Iron Tab ... Stress B Complex With C,e, Zinc and Copper …
Matched Categories: … Vitamin C and analogues …
NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by...
Approved
Nutraceutical
Matched Synonyms: … Reduced nicotinamide adenine diphosphate ... Nicotinamide adenine dinucleotide (reduced) ... Nicotinamide-adenine dinucleotide, reduced …
Matched Description: … electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an ... NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Synonyms: … N-(2-Hydroxyethyl)nicotinamide nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate (ester) …
Matched Description: … It is shown to dilate normal and stenotic coronary arteries and reduces both ventricular preload and ... , most of Europe, India, Philippines, Japan, South Korea, and Taiwan. ... Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia …
An analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.
Experimental
Matched Synonyms: … 6-methyl MP riboside ... 6-methyl MP-riboside ... 6-methylthiopurine riboside
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Acadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) for the prevention of adverse cardiovascular outcomes in patients undergoing coronary artery bypass graft (CABG) surgery. It is being developed jointly by PeriCor and Schering-Plough. Acadesine has been granted Orphan Drug Designation for...
Investigational
Matched Synonyms: … AICA-riboside
Matched Description: … It is being developed jointly by PeriCor and Schering-Plough. ... Acadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties that is currently …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem]
Experimental
Matched Name: … Nicotinamide Mononucleotide …
Matched Description: … Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem] ... A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … Reduced nicotinamide adenine dinucleotide phosphate …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Allopurinol riboside is a nucleoside analogue of allopurinol with a beta-D-ribofuranosyl moiety at the 1-position.
Investigational
Matched Name: … Allopurinol riboside
Matched Description: … Allopurinol riboside is a nucleoside analogue of [allopurinol] with a beta-D-ribofuranosyl moiety at …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … Purine riboside
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … Carba-nicotinamide-adenine-dinucleotide …
Experimental
Matched Name: … Nicotinamide adenine dinucleotide cyclohexanone …
CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Synonyms: … immunity- and matrix-regulatory cells ... Immunity-and-matrix-regulatory cells …
Matched Description: … anti-fibrotic functions, and being stronger in potential treatment of lung injury and fibrosis. ... CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can ... These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. …
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... ) at the HBG1 and HBG2 promoters ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and
Investigational
Matched Synonyms: … Hypothiocyanite and lactoferrin …
Experimental
Matched Name: … Purine Riboside-5'-Monophosphate …
SP1049C is a novel anthracycline chemotherapeutic agent containing doxorubicin and two nonionic pluronic block copolymers. It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. Preliminary data, in its first clinically tested indication,...
Investigational
Matched Synonyms: … doxorubicin with pluronics F-127 and L-61 ... Doxorubicin HCl with pluronic L-61 and pluronic F-127 …
Matched Description: … Median survival is encouraging and correlates strongly with dose levels.[A260416] ... SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic …
PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).
Investigational
Matched Synonyms: … Human umbilical cord and placental blood plasma …
Matched Description: … PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental ... [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory …
Displaying drugs 1 - 25 of 389 in total