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Displaying drugs 1 - 25 of 971 in total
Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) ... Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein ... Ebola Zaire vaccine (live) …
Matched Name: … Ebola Zaire vaccine (live, attenuated) …
Matched Description: … Ervebo consists of an envelope glycoprotein of the Zaire ebolavirus (Kikwit 1995 strain) fused into a ... The mortality rate of the Zaire species is about 80%. ... [A188994,A188997] In the _Filoviridae_ family, there are five unique Ebolavirus species that are each …
Approved
Matched Synonyms: … Haemagglutinin-strain A (H3N2) …
Matched Name: … Haemagglutinin-strain A(H3N2) …
Approved
Matched Synonyms: … Haemagglutinin-strain B (Victoria) …
Matched Name: … Haemagglutinin-strain B (Victoria-like) …
Approved
Matched Synonyms: … Haemagglutinin-strain B (Yamagata) …
Matched Name: … Haemagglutinin-strain B (Yamagata-like) …
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate …
Matched Name: … Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Description: … Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is ... [PRP]), which is a high molecular weight polymer prepared from the *Haemophilus influenzae* type b strain
Approved
Matched Name: … Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle …
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Synonyms: … gE recombinant Varicella zoster virus (VZV) glycoprotein E ... Recombinant Varicella zoster virus (VZV) glycoprotein E ... gE: Recombinant Varicella Zoster Virus (VZV) glycoprotein E …
Matched Description: … The main immunological component of Shingrix vaccine is glycoprotein E (gE), a protein found on the surface …
Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis for percutaneous use. It is administered to prevent the development of tuberculosis.
Approved
Matched Synonyms: … BCG, Live, Tice Strain
Matched Description: … vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain
Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder and for the prophylaxis of primary or recurrent stage Ta and/or T1 papillary tumors following transurethral resection (TUR). The solution contains live, attenuated strain of Mycobacterium bovis....
Approved
Investigational
Matched Synonyms: … BCG, Live, Connaught Strain
Matched Description: … The solution contains live, attenuated strain of Mycobacterium bovis. ... It is prepared from the Connaught strain of Bacillus Calmette and Guérin. …
Approved
Matched Synonyms: … Haemagglutinin-strain A (H5N1) …
Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.
Approved
Investigational
Matched Synonyms: … Rabies virus vaccine flury-lep strain ... Rabies virus strain flury lep antigen (propiolactone inactivated) …
Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Synonyms: … Bacillus anthracis strain V770-NP1-R antigen ... Bacillus anthracis strain V770-NP1-R antigens ... Bacillus anthracis strain V770-NP1-R filtrate antigen …
Matched Description: … It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H1N1) …
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain B (Victoria) …
Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952. It is spread primarily by the bite of infected mosquitos of the Aedes genus. Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia. Prior to...
Approved
Matched Synonyms: … Chikungunya virus LR2006 OPY1 (attenuated strain) antigen …
Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Synonyms: … Varicella virus vaccine live (oka-merck) strain ... Varicella-zoster virus strain oka/merck live antigen ... Varicella-zoster virus strain oka/merck live (attenuated) antigen …
Matched Description: … Both Varivax and Zostavax are composed of a lyophilized preparation of live, attenuated Oka/Merck strain
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Synonyms: … Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying …
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human …
Matched Description: … [L44146] It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the …
Infection with pathogenic filoviruses, such as Zaire ebolavirus (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as 90%.[A225933, A225938] Virtually all steps of the EBOV lifecycle have been targeted for therapeutic development. However, to date, the most successful...
Approved
Investigational
Matched Description: … [A225933] Ansuvimab, formerly mAb114, is a fully human IgG1 mAb derived from a survivor of the 1995 Kikwit ... appears to be the development of monoclonal antibodies (mAbs) against the GP1,2 surface glycoprotein
Matched Categories: … Zaire Ebolavirus Glycoprotein-directed Antibody …
Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...
Approved
Matched Products: … E-Z-paque 95% ... Barosperse for Susp 95% ... Tonopaque for Suspension 95% …
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL …
Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Products: … Oxygen/Nitrogen 5/95 ... Carbon Dioxide/Oxygen 5/95 ... Carbon Dioxide Oxygen Mixture 5/95
Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … Synagis is a composite of human (95%) and murine (5%) antibody sequences. …
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … 2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … 2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein
Displaying drugs 1 - 25 of 971 in total