Displaying drugs 3626 - 3650 of 11300 in total
Noscapine
Approved
Investigational
Cefotetan
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Approved
Matched Description: … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range ... A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. …
Indinavir
A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Approved
Matched Description: … A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. …
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … generic and as a brand name product. ... [L6301] The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs. ... sees extensive use worldwide via millions of prescriptions annually and has since become available as a …
Lisdexamfetamine
Lisdexamfetamine is a prodrug of dextroamphetamine, a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February...
Approved
Investigational
Matched Description: … Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine …
Leniolisib
Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of...
Approved
Investigational
Matched Description: … Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). ... [L45758] APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Vibrio cholerae CVD 103-HgR strain live antigen
Vibrio cholerae CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against Vibrio cholerae serogroup O1. Cholera is an acute bacterial disease of the small intestine caused by Vibrio cholerae, which is gram-negative bacteria. Two serogroups of V. cholerae, O1 and O139, are causative...
Approved
Investigational
Matched Description: … _Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization ... [A244494] Cholera outbreaks remain a major global public health problem that mainly affects countries …
Manganese gluconate
Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder. Manganese gluconate is a direct ingredient in food substances...
Approved
Matched Description: … Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. ... In pharmaceutical preparations it is used as a [DB06757] supplement. ... Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O …
Ferric chloride
Approved
Experimental
Nicardipine
A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Description: … A potent calcium channel blockader with marked vasodilator action. …
Margetuximab
The HER2 oncoprotein, the product of the human ERBB2/mouse neu genes, is a member of the HER family of receptor tyrosine kinases that includes the epidermal growth factor receptor (EGFR). Of the various subtypes of breast cancer, HER2-positive breast cancer is characterized by ERBB2 overexpression, a higher grade, a more...
Approved
Investigational
Matched Description: … higher grade, a more aggressive phenotype, and a worse prognosis compared to HER2-negative cancer. ... The HER2 oncoprotein, the product of the human _ERBB2_/mouse _neu_ genes, is a member of the HER family ... subtypes of breast cancer, HER2-positive breast cancer is characterized by _ERBB2_ overexpression, a …
Ranolazine
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Description: … is a promising anti-anginal therapy. ... Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant ... [A189234] Ranolazine is a well-tolerated piperazine derivative used for the management of this condition …
Mumps virus strain B level jeryl lynn live antigen
Mumps virus strain B level jeryl lynn live antigen is a live attenuated virus vaccine for subcutenous injection. It is an active immunization against mumps, which is a common childhood disease.
Approved
Investigational
Matched Description: … It is an active immunization against mumps, which is a common childhood disease. ... Mumps virus strain B level jeryl lynn live antigen is a live attenuated virus vaccine for subcutenous …
Nepafenac
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Description: … Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop …
Monomethyl fumarate
Approved
Experimental
Investigational
Diazepam
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and...
Approved
Illicit
Investigational
Vet approved
Matched Description: … a long duration of action. ... A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and ... It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of …
Chlorpromazine
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Idursulfase
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Description: … Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. ... Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons. ... Idursulfase is produced by recombinant DNA technology in a human cell line. …
Potassium lactate
Approved
Dantrolene
Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other hydantoin derivates such as phenytoin.
Approved
Investigational
Matched Description: … Chemically, dantrolene is a hydantoin derivative, but does not exhibit antiepileptic activity like other …
Penciclovir
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Description: … Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. ... Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment …
Eltrombopag
Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Description: … ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets …
Displaying drugs 3626 - 3650 of 11300 in total