Displaying drugs 3701 - 3725 of 11727 in total
Levobetaxolol
Levobetaxolol is a beta-blocker used to lower the pressure in the eye to treat conditions such as glaucoma. It was marketed as a 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon but has been discontinued.
Approved
Investigational
Matched Description: … Levobetaxolol is a beta-blocker used to lower the pressure in the eye to treat conditions such as glaucoma ... It was marketed as a 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon …
Ecallantide
Ecallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema. Ecallantide is a recombinant 60-amino-acid protein produced in Pichia pastoris yeast cells that contains three intramolecular disulfide bonds [FDA Label]. It was discovered by phage display technology . It shares...
Approved
Investigational
Matched Description: … By reversibly binding to plasma kallikrein, ecallantide displays a rapid on-rate and a slow off-rate ... Ecallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic ... Ecallantide is a recombinant 60-amino-acid protein produced in _Pichia pastoris_ yeast cells that contains …
Pegcetacoplan
Pegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH).[A235000,L34095] Prior to its FDA approval, patients with PNH were typically treated with the C5 inhibiting monoclonal antibody eculizumab. Patients given eculizumab experienced less hemolysis caused by the membrane attack complex, but were still somewhat susceptible to...
Approved
Matched Description: … Pegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria ... [A235000,A235005] Pegcetacoplan is a pegylated C3 inhibitor that can disrupt the processes leading to ... [A235000,A235005] Pegcetacoplan was developed out of a need for an inhibitor of complement mediated hemolysis …
Quaternium-15
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. In 2005,...
Approved
Experimental
Matched Description: … Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including ... Sensitivity to Quaternium-15 may be identified with a clinical patch test. ... contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. …
Cladribine
An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia. Cladribine is also used to treat relapsing forms of multiple sclerosis.
Approved
Investigational
Noscapine
Approved
Investigational
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … generic and as a brand name product. ... [L6301] The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs. ... sees extensive use worldwide via millions of prescriptions annually and has since become available as a …
Lisdexamfetamine
Lisdexamfetamine is a prodrug of dextroamphetamine, a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February...
Approved
Investigational
Matched Description: … Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine …
Leniolisib
Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). The FDA approved leniolisib on March 24, 2023, making it the first treatment for activated phosphoinositide 3-kinase delta syndrome (APDS). APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby increasing the activity of...
Approved
Investigational
Matched Description: … Leniolisib is a potent and selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ). ... [L45758] APDS is a primary immunodeficiency caused by mutations in genes encoding the PI3Kδ, thereby …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Vibrio cholerae CVD 103-HgR strain live antigen
Vibrio cholerae CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against Vibrio cholerae serogroup O1. Cholera is an acute bacterial disease of the small intestine caused by Vibrio cholerae, which is gram-negative bacteria. Two serogroups of V. cholerae, O1 and O139, are causative...
Approved
Investigational
Matched Description: … _Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization ... [A244494] Cholera outbreaks remain a major global public health problem that mainly affects countries …
Manganese gluconate
Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder. Manganese gluconate is a direct ingredient in food substances...
Approved
Matched Description: … Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. ... In pharmaceutical preparations it is used as a [DB06757] supplement. ... Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O …
Ferric chloride
Approved
Experimental
Nicardipine
A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Description: … A potent calcium channel blockader with marked vasodilator action. …
Margetuximab
The HER2 oncoprotein, the product of the human ERBB2/mouse neu genes, is a member of the HER family of receptor tyrosine kinases that includes the epidermal growth factor receptor (EGFR). Of the various subtypes of breast cancer, HER2-positive breast cancer is characterized by ERBB2 overexpression, a higher grade, a more...
Approved
Investigational
Matched Description: … higher grade, a more aggressive phenotype, and a worse prognosis compared to HER2-negative cancer. ... The HER2 oncoprotein, the product of the human _ERBB2_/mouse _neu_ genes, is a member of the HER family ... subtypes of breast cancer, HER2-positive breast cancer is characterized by _ERBB2_ overexpression, a …
Nepafenac
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Description: … Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop …
Monomethyl fumarate
Approved
Experimental
Investigational
Mumps virus strain B level jeryl lynn live antigen
Mumps virus strain B level jeryl lynn live antigen is a live attenuated virus vaccine for subcutenous injection. It is an active immunization against mumps, which is a common childhood disease.
Approved
Investigational
Matched Description: … It is an active immunization against mumps, which is a common childhood disease. ... Mumps virus strain B level jeryl lynn live antigen is a live attenuated virus vaccine for subcutenous …
Ranolazine
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Description: … is a promising anti-anginal therapy. ... Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant ... [A189234] Ranolazine is a well-tolerated piperazine derivative used for the management of this condition …
Diazepam
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and...
Approved
Illicit
Investigational
Vet approved
Matched Description: … a long duration of action. ... A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and ... It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of …
Idursulfase
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Description: … Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. ... Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons. ... Idursulfase is produced by recombinant DNA technology in a human cell line. …
Displaying drugs 3701 - 3725 of 11727 in total