Displaying drugs 351 - 375 of 11559 in total
Idarubicin
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Categories: … Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Allopurinol
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals .
Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially ... Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective …
Tiludronic acid
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Description: … Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate ... [A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's ... [A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification …
Matched Categories: … Phospholipases A, antagonists & inhibitors …
Matched Categories: … Phospholipases A, antagonists & inhibitors …
Fructose
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Chloramphenicol succinate
Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Description: … [A192987] Chloramphenicol is a bacteriostatic antibiotic. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Clonidine
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.[L7237,L7240,L7243,L7246]
Clonidine was granted FDA approval on 3 September 1974.
Approved
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Amantadine
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Description: … An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. …
Matched Categories: … Influenza A M2 Protein Inhibitor …
Matched Categories: … Influenza A M2 Protein Inhibitor …
Meradimate
Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Description: … products as a UV filter. ... Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different …
Matched Mixtures name: … Clinic A Retinol Vital Day Moist Lot Spf20 …
Matched Mixtures name: … Clinic A Retinol Vital Day Moist Lot Spf20 …
Cetylpyridinium
Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Description: … Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. …
Matched Mixtures name: … Kank-A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Kank-A …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Mafenide
Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. In November 2022, the use of mafenide acetate (powder...
Approved
Vet approved
Withdrawn
Matched Description: … Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. …
Avibactam
Avibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metronidazole, and the treatment of complicated urinary tract infections, including pyelonephritis caused by antibiotic resistant-pathogens,...
Approved
Matched Description: … Avibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime ( …
Amifostine
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Approved
Investigational
Matched Description: … A phosphorothioate proposed as a radiation-protective agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Propyliodone
Radiopaque medium usually in oil; used in bronchography.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Recombinant Cholera Toxin B Subunit
Recombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Antihemophilic factor, human recombinant
Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Hemophilia A …
Podophyllin
Podophyllin is a resin extracted from the roots of Podophyllum peltatum (American mandrake) and Podophyllum emodi, which contains numerous compounds, amongst which is podophyllin (as well as the drug podophyllotoxin). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Approved
Matched Description: … Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Estramustine
A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Approved
Investigational
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Matched Description: … A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also …
Alprostadil
Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Description: … Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator ... A257088]
Alprostadil is also used in neonatal patients with congenital heart defects that depend on a …
Diethylpropion
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Description: … A appetite depressant considered to produce less central nervous system disturbance than most drugs in …
Phendimetrazine
Phendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.
Approved
Illicit
Matched Description: … Phendimetrazine is a weight loss medication. ... Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention …
Ferumoxytol
Ferumoxytol is an intravenously administered iron preparation indicated in the EU and the US for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD) .
It is comprised of superparamagnetic iron oxide nanoparticles which are coated by a semi-synthetic carbohydrate shell in an isotonic, neutral...
Approved
Investigational
Matched Description: … It is comprised of superparamagnetic iron oxide nanoparticles which are coated by a semi-synthetic carbohydrate …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Carfilzomib
Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor. FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.
Approved
Investigational
Matched Description: … It is also a selective proteasome inhibitor. ... Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index …
Dipotassium phosphate
Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Description: … as a source of phosphorus and potassium as well as a buffering agent. ... Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ferumoxides
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 351 - 375 of 11559 in total