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Displaying drugs 651 - 675 of 13635 in total

Triclocarban

Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Description: … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products ... In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products …

Diflunisal

Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Description: … Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic ... Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of …

Potassium citrate

Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat...
Approved
Investigational
Vet approved
Matched Description: … In the monohydrate form it is highly hygroscopic and deliquescent. ... Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis ... It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. …
Matched Mixtures name: … Multi-force for Women Tab …

Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Systemic Use ... Antifungals for Dermatological Use …
Matched Products: … Lamisil AT for Jock Itch …

Motixafortide

Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … , for use in stem cell mobilization prior to autologous stem cell transplant in patients with multiple ... Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection ... of C-X-C Motif Chemokine Receptor 4 (CXCR4), a protein that helps to anchor stem cells to bone marrow …

Hydroxyzine

Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment ... Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane ... L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in …

Isometheptene

Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Approved
Matched Description: … It is used for treating migraines and tension headaches. ... Isometheptene is a sympathomimetic drug that causes vasoconstriction. …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …

Tetrofosmin

Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds. It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.
Approved
Matched Description: … Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788] ... It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. …
Matched Products: … MYOVIEW POWDER FOR INJECTION ... MYOVIEW FOR INJECTION 0.23 mg/vial …

Luspatercept

Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients...
Approved
Investigational
Matched Description: … [A187829,L42455] It was first approved for use in the United States in November 2019 under the brand ... Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin ... name Reblozyl® for the treatment of anemia in patients with beta thalassemia who require regular blood …

Pizotifen

Pizotifen belongs to the class of antamines and is related to cyproheptadine. It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating properties . Some patients receiving pizotifen...
Approved
Matched Description: … Sandomigran is available in a number of countries but is not approved by the FDA nor EMA. ... [A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention ... Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management …

Oritavancin

Oritavancin is a glycopeptide antibiotic used for the treatment of skin infections. It was developed by The Medicines Company (acquired by Novartis). Oritavancin was initially approved by the FDA in 2014 and formulated to combat susceptible gram-positive bacteria that cause skin and skin structure infections. It boasts the option of...
Approved
Investigational
Matched Description: … Oritavancin is a glycopeptide antibiotic used for the treatment of skin infections. ... [A39384,A193482,L8492] On March 12, 2021 the FDA approved Kimyrsa, a complete course of therapy in ... Marketed by Melinta Therapeutics, Kimyrsa offers effective and time-efficient treatment for skin and …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Parecoxib

Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral...
Approved
Matched Description: … A letter of non-approval for parecoxib was issued by the FDA in 2005. ... It is approved through much of Europe for short term perioperative pain control much in the same way ... Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx …
Matched Products: … Dynastat Powder for Solution for Injection 40mg ... DYNASTAT (POWDER FOR SOLUTION FOR INJECTION 40 MG/2ML) ... Dynastat Powder and Solvent for Solution for Injection 40mg …

Regadenoson

Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Approved
Investigational
Matched Description: … Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial …
Matched Categories: … Adenosine A receptor agonists …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Description: … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria ... [A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …

Liotrix

Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Description: … Administration of levothyroxine alone is sufficient for maintaining serum T4 and T3 levels in most patients ... In fact, administration of T3 may result in supratherapeutic levels of T3. ... a 4 to 1 ratio by weight. …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Description: … in chronic renal failure. ... A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful …
Matched Categories: … Medications that reduce magnesium levels ... Antihypertensive Agents Indicated for Hypertension …

Didanosine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral...
Approved
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced ... This modification prevents the formation of phosphodiester linkages which are needed for the completion ... by a hydrogen. …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …

Avapritinib

Avapritinib, or BLU-285, is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal stromal tumors and advanced systemic mastocytosis.[A189339,L40363] It is one of the first medications available for the treatment of multidrug resistant cancers. Avapritinib shares a...
Approved
Investigational
Matched Description: … [A189327] Avapritinib shares a similar mechanism with [ripretinib]. ... Avapritinib, or BLU-285,[A189327] is a selective tyrosine kinase inhibitor of KIT and platelet derived ... growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal …

Lenograstim

Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Description: … Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent …
Matched Products: … GRANOCYTE 34 FOR INJECTION 263 mcg/ml …

Celiprolol

Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Description: … In 2010 a clinical trial has suggested a use for this medication in the prevention of vascular complications ... Celiprolol is not approved for use by the FDA in the treatment of vascular Ehlers–Danlos syndrome. ... Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina …

Masoprocol

A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Description: … It also serves as an antioxidant in fats and oils. [PubChem] ... A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. ... The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Oxytetracycline

A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Description: … A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety …
Matched Categories: … Antibiotics for Topical Use ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Antiinfectives and Antiseptics for Local Oral Treatment …

Lasofoxifene

Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. It was initially developed as Oporia by Pfizer as...
Approved
Investigational
Matched Description: … atrophy, in which were both rejected for approval by FDA. ... with a newly submitted New Drug Application in 2008. ... It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment …

Nafcillin

A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections ... It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360 ... A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …

Altretamine

An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Approved
Matched Description: … It also acts as a chemosterilant for male houseflies and other insects. …
Displaying drugs 651 - 675 of 13635 in total