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Displaying drugs 226 - 250 of 12359 in total
Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning...
Approved
Matched Synonyms: … 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one …
Matched Iupac: … 2-{6'-oxo-1'-phenyl-1',6'-dihydro-[2,3'-bipyridine]-5'-yl}benzonitrile …
Matched Description: … Perampanel is a noncompetitive AMPA glutamate receptor antagonist. …
Matched Products: … FYCOMPA (2 MG) ... FYCOMPA® 2 MG ... Fypalan 2 mg-Filmtabletten …
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Equine Botulinum Neurotoxin F Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype F. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes F in...
Approved
Experimental
Investigational
Matched Synonyms: … Botulinum Neurotoxin F immune FAB2 (equine) ... BOTULINUM NEUROTOXIN F IMMUNE FAB2, EQUINE …
Matched Name: … Equine Botulinum Neurotoxin F Immune FAB2 …
Matched Description: … Equine Botulinum Neurotoxin F Immune FAB2 is composed of a mixture of immune globulin fragments purified ... from plasma of horses that were previously immunized with botulinum toxin serotype F. ... of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes F
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... in a BCR-ABL fusion protein. ... [A6902,A261796,A261801] The first BCR-ABL inhibitor, [imatinib], was introduced over a decade ago as …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Approved
Experimental
Matched Products: … Dr.g A-clear Balancing Toner ... DR.G A-CLEAR SPOT Repairing SERUM …
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac ... Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and …
Matched Mixtures name: … TUSBRON-A JARABE …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … FILINSEL 24 MG/ML IV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 10 ML X 3 AMPUL …
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid ... (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Iupac: … 5-(hex-3-yn-2-yl)-1-methyl-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … lentiviral vector encoding the human arylsulfatase A (ARSA) gene ... enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a ... Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary …
Matched Description: … lentiviral vector encoding the human arylsulfatase A (ARSA) gene. ... Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically ... modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using a
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Matched Synonyms: … N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol- ... 2-yl)phenyl)urea …
Matched Iupac: … 3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶ …
Matched Description: … maintenance monotherapy resulted in a 22% reduction in the risk of death. ... Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug ... demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although with a
Matched Categories: … Heterocyclic Compounds, 2-Ring …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common ... Interestingly enough, it is precisely via this mechanism why sildenafil was at first researched as a ... recognized as Pfizer's brand name Viagra, sildenafil is currently available generically and even as a
Matched Mixtures name: … DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOXIL 30/50 MG FILM KAPLI TABLET, 3 FILM KAPLI TABLET …
Matched Products: … Managra F/C Tablet 50mg ... Managra F/C Tablet 100mg ... A-Sildenafil Tablets 100mg …
Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties . Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. They...
Approved
Matched Description: … It is a clear viscous liquid at room temperature with non-volatile, stable properties [A33116]. ... Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 ... PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings.
Approved
Matched Mixtures name: … Kerr 100 Triple Dye Dispos-A
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Pentafluoropropane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
Approved
Investigational
Equine Botulinum Neurotoxin G Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype G. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes G in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin G Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Equine Botulinum Neurotoxin D Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype D. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes D in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin D Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Equine Botulinum Neurotoxin B Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype B. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes B in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin B Immune FAB2 is composed of a mixture of immune globulin fragments purified …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … 7-(D-2-Amino-2-phenylacetamido)-3-acetoxymethyl-delta(sup3)-cephem-4-carboxylic acid ... 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct- ... 2-ene-2-carboxylic acid …
Matched Description: … A cephalorsporin antibiotic that is no longer commonly used. …
Matched Salts cas: … 22202-76-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Synonyms: … 5-(2-methylpropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione ... 5-allyl-5-(2-methylpropyl)barbituric acid ... 5-allyl-5-(2'-methyl-n-propyl) barbituric acid …
Matched Iupac: … 5-(2-methylpropyl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index. ... Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety …
Matched Salts cas: … 23554-70-3
Matched Mixtures name: … Fiorinal-C 1/2 ... Teva-tecnal C 1/2 ... Pronal - C1/2 Capsules …
Fluorodopa F 18 is a fluorinated analog of levodopa used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.
Approved
Experimental
Matched Synonyms: … Fluorodopa F-18 …
Matched Iupac: … (2S)-2-amino-3-[2-(¹⁸F)fluoro-4,5-dihydroxyphenyl]propanoic acid …
Matched Description: … Fluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission ... [L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily …
Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Matched Synonyms: … chromium(3+) trichloride …
Matched Iupac: … chromium(3+) ion trichloride …
Matched Description: … Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive …
Matched Mixtures name: … M T E 4 Concentrate Inj ... One-A-day Advance Men's …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 33F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... antigens of *Streptococcus pneumoniae* serotype 33F individually conjugated to the CRM197 protein, a
Domestic dog hair is used in allergenic testing.
Approved
Displaying drugs 226 - 250 of 12359 in total