Displaying drugs 3576 - 3600 of 11855 in total
Albumin iodinated I-125 serum
I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of total blood and plasma volume.
Approved
Matched Description: … I-125 iodinated albumin is a radiolabeled albumin-based diagnostic agent used in the determination of …
Cetirizine
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … One of the most common uses for this drug is for a condition called _allergic rhinitis_. …
Furosemide
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … a higher diuretic potential. ... Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in …
Tioguanine
An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Allogeneic processed thymus tissue
Allogeneic processed thymus tissue is used for immune reconstitution in immune disorders where the patients are severely immunocompromised due to the absence of a functional thymus, such as congenital athymia. As part of the immune system, the thymus is an organ responsible for the maturation and selection of T cells...
Approved
Matched Description: … [L38929] Congenital athymia is a rare condition that leads to the absence of a thymus at birth and a ... an organ responsible for the maturation and selection of T cells [A239814]; thus, patients without a ... reconstitution in immune disorders where the patients are severely immunocompromised due to the absence of a …
Aspergillus nidulans
Aspergillus nidulans is a fungus which can provoke allergic reactions. Aspergillus nidulans extract is used in allergenic testing.
Approved
Matched Description: … Aspergillus nidulans is a fungus which can provoke allergic reactions. …
Evinacumab
Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein 3 (ANGPTL3) and the first drug of its kind. The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the regulation of lipid metabolism - which have made them desirable therapeutic targets in...
Approved
Investigational
Matched Description: … rationale for the development of a therapy targeted against ANGPTL3. ... Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein ... The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the …
Regdanvimab
Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate. Trials...
Approved
Investigational
Matched Description: … Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding ... Trials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 …
Telbivudine
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Description: … Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B …
Florbetaben F-18
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Description: … Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography …
Deucravacitinib
Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. Unlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity to this therapeutic target.[A246938, A246943] This selectivity towards TYK2 may...
Approved
Investigational
Matched Description: … Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. ... to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a …
Lomustine
An alkylating agent of value against both hematologic malignancies and solid tumors.
Approved
Investigational
Bendroflumethiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Naloxegol
Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca. It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain. The advantage of naloxegol over the opioid antagonist naloxone is that its...
Approved
Matched Description: … Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Edetate disodium anhydrous
Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Approved
Vet approved
Matched Description: … Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis …
Tolmetin
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of …
Iobenguane sulfate I-123
Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].
Approved
Investigational
Matched Description: … Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated …
Juniperus ashei pollen
Juniperus ashei pollen is the pollen of the Juniperus ashei plant. Juniperus ashei pollen is mainly used in allergenic testing.
Approved
Sodium aurotiosulfate
Approved
Experimental
Oxyphenisatin acetate
Oxyphenisatin acetate is the pro-drug of oxyphenisatin (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.
Approved
Investigational
Withdrawn
Magnesium Aluminum Silicate
Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant, and
tablet binder. It also...
Approved
Matched Description: … Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite ... It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking ... It also has antacid properties and is used as a component of some over the counter antacid medications …
Granisetron
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Metronidazole
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. ... antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat a …
Dabigatran etexilate
Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects...
Approved
Hydromorphone
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … Hydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine ... carbonyl and the absence of a double bond between the carbon 7 and 8. ... hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a …
Displaying drugs 3576 - 3600 of 11855 in total