Displaying drugs 3626 - 3650 of 11743 in total
Streptococcus pneumoniae type 11a capsular polysaccharide antigen
Streptococcus pneumoniae type 11a capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 11a of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 11a capsular polysaccharide antigen is a vaccine that contains highly purified …
Streptococcus pneumoniae type 19a capsular polysaccharide antigen
Streptococcus pneumoniae type 19a capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 19a of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 19a capsular polysaccharide antigen is a vaccine that contains highly purified …
Cycrimine
Cycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.
Approved
Matched Description: … Cycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment …
Gemtuzumab ozogamicin
Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp. calichensis. Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody [FDA Label]. The antibody is specifically...
Approved
Investigational
Matched Description: … Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin ... derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ... lower dosing regimen and a different schedule in combination with chemotherapy or on its own [L941]. …
Gallium citrate Ga-67
Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy...
Approved
Matched Description: … Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble …
Relatlimab
Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 (LAG-3).[A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013, and has garnered interest in the treatment of a variety of cancers, including leukemia and melanoma. As immune checkpoint...
Approved
Investigational
Matched Description: … Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte ... antibody, entering clinical trials in 2013,[A246155] and has garnered interest in the treatment of a ... [L41265,L41300] It was the first anti-LAG-3 antibody to demonstrate benefit in a Phase 3 study, as well …
Grazoprevir
Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Description: … It can be used in patients with compensated cirrhosis, human immunodeficiency virus co-infection, or ... Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 …
Pinus nigra pollen
Pinus nigra pollen is the pollen of the Pinus nigra plant. Pinus nigra pollen is mainly used in allergenic testing.
Approved
Elaeagnus angustifolia pollen
Elaeagnus angustifolia pollen is the pollen of the Elaeagnus angustifolia plant. Elaeagnus angustifolia pollen is mainly used in allergenic testing.
Approved
Aluminum sesquichlorohydrate
Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts .
Approved
Roxithromycin
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched Description: … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. …
Beeswax
The wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins. Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to produce water-in-oil emulsions. It is also used as a coating...
Approved
Matched Description: … It is also used as a coating in the manufacture of modified-release oral preparations ... Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to …
Tasimelteon
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of...
Approved
Investigational
Matched Description: … Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour ... In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle …
Netarsudil
A Rho kinase inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous
As of December 18, 2017 the FDA approved Aerie Pharmaceutical's Rhopressa (netarsudil ophthalmic solution) 0.02% for the indication of reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Acting as both a rho...
Approved
Matched Description: … Acting as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel ... A Rho kinase inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous …
Smallpox (Vaccinia) Vaccine, Live
The New York City Board of Health strain of Vaccinia is a viral strain used as a component of some smallpox vaccinations. ACAM2000, a percutaneously administered smallpox vaccine that was approved by the FDA in 2007, contains live antigens of this strain.
Approved
Matched Description: … The New York City Board of Health strain of _Vaccinia_ is a viral strain used as a component of some ... [L12747] ACAM2000, a percutaneously administered smallpox vaccine that was approved by the FDA in 2007 …
Casuarina equisetifolia pollen
Casuarina equisetifolia pollen is the pollen of the Casuarina equisetifolia plant. Casuarina equisetifolia pollen is mainly used in allergenic testing.
Approved
Prazosin
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists.
Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Description: … Prazosin is a drug used to treat hypertension. …
Peramivir
Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic. Being an influenza virus neuraminidase inhibitor, peramivir works by...
Approved
Investigational
Matched Description: … Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. ... by the US Department of Health and Human Services as part of the government's effort to prepare for a …
Ornithine
Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Description: … L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine …
Myrothecium verrucaria
Myrothecium verrucaria is a fungus which can provoke allergic reactions. Myrothecium verrucaria extract is used in allergenic testing.
Approved
Matched Description: … Myrothecium verrucaria is a fungus which can provoke allergic reactions. …
Tramadol
Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain. It is considered...
Approved
Investigational
Matched Description: … its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a ... Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor ... It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th …
Vismodegib
Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. Since it targets the hedgehog signaling pathway, vismodegib...
Approved
Investigational
Matched Description: … [A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule …
Trifarotene
Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to vitamin A, though later generation retinoids such as trifarotene and adapalene bear little...
Approved
Investigational
Matched Description: … [L9013] Retinoids are a class of medications structurally and functionally analogous to [vitamin A], ... Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved ... generation retinoids such as trifarotene and [adapalene] bear little structural resemblance to vitamin A …
Displaying drugs 3626 - 3650 of 11743 in total