Displaying drugs 5076 - 5100 of 11308 in total
Droloxifene
Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more rapidly than tamoxifen. Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell...
Investigational
Matched Description: … Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor ... It may have a particular role in situations in which rapid pharmacokinetics, or an increased antiestrogenic ... Droloxifene may also be a potentially useful agent for the treatment of postmenopausal osteoporosis because …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Nonivamide
Nonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species. The structures of DB06774 and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) .
Nonivamide is a flavoring ingredient. Nonivamide is an...
Investigational
Matched Description: … Nonivamide is a flavoring ingredient. Nonivamide is an organic compound and a capsaicinoid. ... It is naturally found in chili peppers but manufactured to produce a synthetic form for various pharmacologic …
ARO-APOC3
ARO-APOC3 is an investigational RNAi therapeutic targeting apolipoprotein C-III (APOC3). It received an Orphan Drug designation by the FDA for the treatment of familial chylomicronemia syndrome.
Investigational
Cymarin
Experimental
Matched Iupac: … methoxy-6-methyloxan-2-yl]oxy}-11a-methyl-1-(5-oxo-2,5-dihydrofuran-3-yl)-hexadecahydro-1H-cyclopenta[a] …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Flortaucipir
Flortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Methyl-1-testosterone
Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It is a derivative of 1-testosterone with a methyl group in the carbon 17. Methyl-1-testosterone is considered a prohibited doping substance.
Experimental
Illicit
Matched Iupac: … 11aS)-1-hydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is a derivative of 1-testosterone with a methyl group in the carbon 17. ... Methyl-1-testosterone is considered a prohibited doping substance. ... Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never …
Matched Description: … It is a derivative of 1-testosterone with a methyl group in the carbon 17. ... Methyl-1-testosterone is considered a prohibited doping substance. ... Methyl-1-testosterone is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never …
BQ-123
BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
Investigational
Matched Iupac: … 1H-indol-3-yl)methyl]-6-(2-methylpropyl)-1,4,7,10,13-pentaoxo-3-(propan-2-yl)-hexadecahydro-1H-pyrrolo[1,2-a] …
Trestolone acetate
Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate ester of DB05830.
Experimental
Matched Iupac: … ,9aR,9bS,11aS)-4,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of …
Matched Description: … Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of …
Boldenone undecylenate
Illicit
Vet approved
Matched Iupac: … 3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Saralasin
Investigational
ADU-S100
ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable...
Investigational
Matched Description: … Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. ... ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon ... human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a …
Bentiromide
Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. It is typically administered orally. Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is...
Investigational
Withdrawn
Matched Description: … Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Maxacalcitol
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Fenthion
Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase...
Vet approved
Matched Description: … Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Guar gum
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tocopherylquinone
Experimental
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
p-Coumaric acid
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Hydroxyprogesterone
Experimental
Matched Iupac: … -1-acetyl-1-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Dimethandrolone Undecanoate
Dimethandrolone Undecanoate is under investigation in clinical trial NCT03455075 (Study of Spermatogenesis Suppression With DMAU Alone or With LNG Versus Placebo Alone in Normal Men).
Investigational
Matched Iupac: … ,10S,11aS)-4,10,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Lonaprisan
Lonaprisan is under investigation in clinical trial NCT00555919 (ZK 230211 in Postmenopausal Woman With Metastatic Breast Cancer).
Investigational
Matched Iupac: … hydroxy-11a-methyl-1-(1,1,2,2,2-pentafluoroethyl)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a] …
Aprobarbital
Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment indicated for the use of aprobarbital was subsequently insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives...
Experimental
Illicit
Matched Description: … Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. ... A primary treatment indicated for the use of aprobarbital was subsequently insomnia. …
Lenomorelin
Lenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others.
Investigational
Alcuronium
A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
Experimental
Matched Description: … A non-depolarizing skeletal muscle relaxant similar to [tubocurarine]. …
ASP-4058
ASP4058 has been used in trials studying Food Effect of ASP4058 and Pharmacokinetics of ASP4058.
Investigational
Azidocillin
Azidocillin is a penicillin antibiotic similir to ampicillin.
Experimental
Matched Description: … Azidocillin is a penicillin antibiotic similir to ampicillin. …
Displaying drugs 5076 - 5100 of 11308 in total