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Displaying drugs 26 - 40 of 40 in total

Folic acid

Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Description: … Levoleucovorin and leucovorin are analogs of tetrahydrofolate (THF) and are able to bypass DHFR reduction ... cofactor for enzymes involved in DNA and RNA synthesis. ... therefore prevent the formation of DHF and THF. …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Isotonix Advanced B-complex Vitamins With Potassium and Magnesium …
Matched Salts name: … Folate sodium …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... ferrous sulfate and folic acid ... ferrous fumarate and folic acid …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Salts name: … Dexamethasone sodium phosphate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... dexamethasone and antibiotics ... dexamethasone and antiinfectives ... dexamethasone and antiinfectives …
Matched Products: … DEXAMETHASONE Sodium Phosphate ... Dexamethasone Sodium Phosphate ... Dexamethasone Sodium Phosphates …

Bendroflumethiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … bendroflumethiazide and potassium ... bendroflumethiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones …

Thiamine

Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … and the nervous and digestive systems. ... It is essential for normal growth and development and helps to maintain proper functioning of the heart ... It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. …
Matched Mixtures name: … Chela Potassium Plus ... Potassium Plus Vit B Complex ... Multi Vitamin and Fluoride …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …

Hydroflumethiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
Approved
Investigational
Withdrawn
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … hydroflumethiazide and potassium ... Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Vonoprazan

Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Description: … Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+- ... Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require ... In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and …
Matched Categories: … Potassium-competitive Acid Blockers ... Alimentary Tract and Metabolism ... vonoprazan, amoxicillin and metronidazole ... vonoprazan, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Delamanid

Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Description: … response to standardized antituberculosis treatments as [DB00951] and [DB01045]. ... It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in ... Delamanid is approved by the EMA and is marketed under the trade name Deltyba as oral tablets. …

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Description: … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …

Saprisartan

Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
Matched Salts name: … Saprisartan potassium …

Telcagepant

Telcagepant has been investigated for the treatment of Migraine. It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the...
Investigational
Matched Description: … CGRP and its receptors are found in areas of the central and peripheral nervous system that are important ... During migraine attacks, CGRP activates these receptors and facilitates the transmission of pain impulses …
Matched Salts name: … Telcagepant potassium …

Vanoxerine

Vanoxerine is a highly selective dopamine transporter antagonist. It was synthesized in the late 1970s and developed as a potential treatment for depression. Vanoxerine was later evaluated as a potential treatment for cocaine addiction due to its ability to block dopamine reuptake with a slower dissociation rate than cocaine. Although...
Investigational
Matched Description: … agent due to its ability to block the hKV11.1 (hERG) cardiac potassium channel. ... It was synthesized in the late 1970s and developed as a potential treatment for depression. ... [A248555] Vanoxerine is an investigational drug and has not been approved for therapeutic use. …

Elinogrel

A P2Y12 inhibitor and platelet aggregation inhibitor.
Investigational
Matched Description: … A P2Y12 inhibitor and platelet aggregation inhibitor. …
Matched Salts name: … Elinogrel potassium …

Flupirtine

Flupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe. It is not approved for use in the U.S. or Canada, but is currently in phase II trials for the treatment of fibromyalgia.
Investigational

Morniflumate

Morniflumate is a non-steroidal anti-inflammatory drug with antipyretic properties. It is the morpholinoethyl ester of niflumic acid . In one study, post morniflumate ingestion, physical examination and clinical symptoms of those with bronchitis showed improvement .
Experimental
Matched Description: … In one study, post morniflumate ingestion, physical examination and clinical symptoms of those with bronchitis …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Displaying drugs 26 - 40 of 40 in total