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Displaying drugs 651 - 675 of 749 in total
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human …
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ARANTIL TOPIC ... VERAN-D ... VERAN D® CAPSULAS 20 MG …
Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Description: … 5000 and about 90% of the material within the range of 2000-9000. ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than ... It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … FRAGMIN INJECTION 10,000 iu/ml (WITH PRESERVATIVE) …
Polymeric phosphoric acid ester of estradiol.
Approved
Matched Synonyms: … (17-beta)-Estra-1,3,5(10)-triene-3,17-diol polymer with phosphoric acid …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion ... protein with adnectin, anti-(human growth differentiation factor 8) (human clone bms-986089 fibronectin …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and ... Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy). …
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE WITH
Matched Description: … Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … , anti-(human tissue factor pathway inhibitor) (human monoclonal 1093884 .gamma.2-chain), disulfide with
Investigational
Matched Synonyms: … anti-(human programmed cell death protein 1) (human monoclonal bi754091 .gamma.4-chain), disulfide with
Investigational
Matched Synonyms: … proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 .gamma.4-chain), disulfide with
Matched Categories: … Amino Acids, Peptides, and Proteins …
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Investigational
Matched Synonyms: … necrosis factor superfamily protein TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide with
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Matched Description: … antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and ... Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and
Matched Categories: … olodaterol and tiotropium bromide ... formoterol and tiotropium bromide …
Matched Products: … SPIRIVA INHALATION CAPSULE 18 mcg with HandiHaler …
Investigational
Matched Synonyms: … anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 1a9 .gamma.1-chain), disulfide with
Investigational
Matched Synonyms: … OF NEWLY DIAGNOSED X-LINKED SEVERE COMBINED IMMUNODEFICIENCY (X-SCID) PATIENTS, TRANSDUCED EX VIVO WITH
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … CHAIN (HUMAN SUSHI DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT ... RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION PROTEIN WITH
Matched Description: … the activation and proliferation of natural killer cells and CD8+ memory T cells, which also synergistically ... transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (BCG) immunotherapy; however ... initial treatment with BCG. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -chain), disulfide with human-mouse monoclonal huvtm1.1 .kappa.-chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 2g11 .gamma.1-chain), disulfide with
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4-chain)), disulfide with
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Synonyms: … 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy …
Matched Description: … The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects ... very low-density lipoprotein (VLDL). ... for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and ezetimibe ... sitagliptin and simvastatin ... simvastatin and fenofibrate ... simvastatin and acetylsalicylic acid ... simvastatin, acetylsalicylic acid and ramipril …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(hepatitis b surface antigen) (human monoclonal gc1102 .gamma.1-chain), disulfide with
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN), DISULFIDE WITH
Matched Description: … is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … necrosis factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with
Investigational
Matched Synonyms: … glycoprotein ectodomain epitope g-iii) (mus musculus monoclonal 62-71-3 .gamma.2b-chain), disulfide with ... evelyn-rockitniki-abelseth glycoprotein ectodomain epitope g-iii) (mus musculus monoclonal .gamma.2-chain), disulfide with
NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). It is under investigation for the treatment of retinitis pigmentosa and age-related macular degeneration.
Investigational
Matched Synonyms: … allogenic retinal epithelial cells transfected with plasmid vector expressing ciliary neurotrophic growth …
Matched Description: … [L46762] It is under investigation for the treatment of retinitis pigmentosa and age-related macular …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Displaying drugs 651 - 675 of 749 in total