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Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Octinoxate

Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Description: … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize ... Its use in pharmaceutical and cosmetic formulations is approved by FDA. ... nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and …
Matched Mixtures name: … Soleil Satin - Eml Top ... Top White ... Hope In A Tinted Moisturizer …
Matched Categories: … Emollients and Protectives …
Matched Products: … Soleil D'uv - Liq Top 3% ... Huile Soleil - Liq Top 4% ... Bobbi Brown Beach Leave-IN Hair Conditioner SPF 15 …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

PMC-403

PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …

TSHA-101

Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... has structural and functional characteristics similar to those of endogenous factor IX. ... has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Allantoin

Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated ... , in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions [A32213]. …
Matched Mixtures name: … Phen-oris - Ont Top ... Aspiera Wound Care and Antiseptic ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Basic Ointments and Protectants ... Herbs and Natural Products …
Matched Products: … Soothex - Crm Top 1% ... Atobos Centella and Wash ... Healing Foot and Leg Balm …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Lavender oil

Approved
Experimental
Matched Synonyms: … Lavandula minor flowering top oil ... Lavandula spica flowering top oil ... Lavandula fragrans flowering top oil …
Matched Mixtures name: … Euky Bear Antiseptic Spray …

Aluminum zirconium tetrachlorohydrex gly

Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Body Satin Antiperspirant and Deodorant ... Ap 22% (regular,sport,musk and Unscented) ... Mate Antiperspirant - Stk Top 20% …

Triclosan

An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, …
Matched Mixtures name: … Benzocaine and Triclosan ... Benzocaine and Triclosan ... APRIL Bath and Shower Anti-bacterial Hand 3 Pack …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Topco Antibacterial ... G-995 - Lot Top 0.1% ... Bio-perle - Lot Top 0.1% …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … MENOPUR multidose 600IU Powder and Solvent for Solution for Injection ... Menopur Powder for Injection and Solvent 75 IU ... MENOPUR multidose 1200IU Powder and Solvent for Solution for Injection …

Selenium Sulfide

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Topco Associates ... Head and Shoulders Itch ... Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Guaifenesin

Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that time the agent has been a combination...
Approved
Investigational
Vet approved
Matched Description: … over-the-counter cough and cold products and is currently a widely available over-the-counter generic ... Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and ... continues to be one of very few - if not perhaps the only drug that is readily available and used as …
Matched Mixtures name: … Topco tussin cf max ... Premier Value Chest Congestion and cough releif DM ... Robitussin Cough and Cold D …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … Topco Mucus Relief ... COFEN 50 COUGH MIXTURE 50 mg/5 ml ... COFEN 100 COUGH MIXTURE 100 mg/5 ml …

Witch hazel

Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Avedana HEMORRHOIDAL COOLING Gel …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … W Lab WATER BEAM MASK ... W Lab HONEY BEAM MASK ... Up and Up Medicated Hemorrhoidal Pads …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …

Chamomile

Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Matricaria Recutita Flower ... Matricaria Recutita L. Flower ... Matricaria Recutita Preparation …
Displaying drugs 51 - 75 of 501 in total