Displaying drugs 76 - 100 of 474 in total
Givastomig
Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 and 4.1BB Bispecific Antibody …
Matched Description: … Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody. …
Matched Description: … Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody. …
RP-72
Investigational
Matched Synonyms: … CXC chemokine receptor types 1 and 2 inhibitor RP72 ... 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin …
S,R-Warfarin alcohol
Experimental
Matched Name: … S,R-Warfarin alcohol …
Matched Categories: … Warfarin and isomers …
Matched Categories: … Warfarin and isomers …
Tolbutamide
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 1-Butyl-3-(p-tolylsulfonyl)urea ... 1-Butyl-3-(p-methylphenylsulfonyl)urea ... N-Butyl-N'-(p-tolylsulfonyl)urea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … Tolbutamide and its metabolites are excreted in urine (75-85%) and feces. ... It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea ... increase the number and sensitivity of insulin receptors. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Description: … Tolbutamide and its metabolites are excreted in urine (75-85%) and feces. ... It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea ... increase the number and sensitivity of insulin receptors. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Imidocarb
Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
Vet approved
Matched Synonyms: … 1,3-bis(3-(2-imidazolin-2-yl)phenyl)urea ... N,N'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea …
Matched Iupac: … 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea …
Matched Description: … of infection with Babesia and other parasites. ... Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment …
Matched Iupac: … 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea …
Matched Description: … of infection with Babesia and other parasites. ... Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment …
R,S-Warfarin alcohol
Experimental
Matched Name: … R,S-Warfarin alcohol …
Matched Categories: … Warfarin and isomers …
Matched Categories: … Warfarin and isomers …
Penicillium glaucum
Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus …
Chlormerodrin
Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Approved
Withdrawn
Matched Synonyms: … 1-[3-(chloromercuri)-2-methoxypropyl]urea …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Matched Description: … The radiolabeled form has been used as a diagnostic and research tool. ... It is no longer used and has been replaced with new classes of diuretic drugs. …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …
Matched Description: … The radiolabeled form has been used as a diagnostic and research tool. ... It is no longer used and has been replaced with new classes of diuretic drugs. …
PMC-403
PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …
TSHA-101
Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …
Aluminum zirconium octachlorohydrex gly
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. ... Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Dior Homme Sans Alcohol Free Antiperspirant ... Suave IS Sweet Pea and Violet Antiperspirant and Deodorant ... Degree Orange Flower and Cranberry Antiperspirant and Deodorant …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Dior Homme Sans Alcohol Free Antiperspirant ... Suave IS Sweet Pea and Violet Antiperspirant and Deodorant ... Degree Orange Flower and Cranberry Antiperspirant and Deodorant …
AT9283
AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.
Investigational
Matched Synonyms: … 1-Cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-urea …
Matched Description: … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid …
Matched Description: … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid …
LP-184
Investigational
Matched Synonyms: … N-HYDROXY-N-(METHYLACYLFULVENE)UREA ... HYDROXY-1-((6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXO-6',7'-DIHYDROSPIRO(CYCLOPROPANE-1,5'-INDEN)-3'-YL)METHYL)UREA ... UREA, N-(((6'R)-6',7'-DIHYDRO-6'-HYDROXY-2',4',6'-TRIMETHYL-7'-OXOSPIRO(CYCLOPROPANE-1,5'-(5H)INDEN)- …
Matched Iupac: … (6'R)-6'-hydroxy-2',4',6'-trimethyl-7'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-inden]-3'-yl]methyl}urea …
Matched Iupac: … (6'R)-6'-hydroxy-2',4',6'-trimethyl-7'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-inden]-3'-yl]methyl}urea …
MM-111
MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
CLL1-CD33 compound chimeric antigen receptor T cells
Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …
Vitamin A
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … all-trans-retinyl alcohol ... all-trans-vitamin A alcohol …
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... It is enriched in the liver, egg yolks, and the fat component of dairy products. ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina …
Matched Mixtures name: … Vitamin A and D ... A and D Ointment ... Calci A and D Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... It is enriched in the liver, egg yolks, and the fat component of dairy products. ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina …
Matched Mixtures name: … Vitamin A and D ... A and D Ointment ... Calci A and D Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
NS-3728
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Synonyms: … N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Reteplase
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Colestipol
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
SNS-314
SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis, leading to multiple rounds of endoreduplication and eventually cell death. SNS-314 inhibits tumor growth in a variety of preclinical models, and...
Investigational
Matched Synonyms: … 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Iupac: … 1-(3-chlorophenyl)-3-{5-[2-({thieno[3,2-d]pyrimidin-4-yl}amino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... SNS-314 inhibits tumor growth in a variety of preclinical models, and it is now being tested in single …
Matched Iupac: … 1-(3-chlorophenyl)-3-{5-[2-({thieno[3,2-d]pyrimidin-4-yl}amino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... SNS-314 inhibits tumor growth in a variety of preclinical models, and it is now being tested in single …
Romilkimab
Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …
DCVAC/OvCa
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …
CHF5633
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 76 - 100 of 474 in total