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Displaying drugs 76 - 100 of 329 in total
Brimonidine
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Macitentan
Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension. It was first approved by the FDA in 2013. Macitentan differs from its predecessor bosentan due to its lower risk of hepatotoxicity.
Approved
Brivudine
Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Approved
Investigational
Ambroxol
Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Salts name: … Edrophonium bromide …
Lonafarnib
Hutchinson-Gilford progeria syndrome (HGPS) is a rare autosomal dominant disorder estimated to affect approximately one in 20 million individuals resulting in adverse symptoms associated with premature ageing: skeletal dysplasia, joint contractures, atherosclerosis, myocardial fibrosis/dysfunction, scleroderma-like cutaneous effects, lipoatrophy, alopecia, and a severe failure to thrive; HGPS is uniformly fatal.[A224379, A224384,...
Approved
Investigational
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Benzalkonium
Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Salts name: … Benzalkonium bromide …
Binimetinib
Binimetinib, also known as Mektovi, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with Encorafenib.[A34275,L3335]
On June 27, 2018, the Food and Drug Administration approved the combination of Encorafenib and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients...
Approved
Investigational
Dequalinium
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Salts name: … Dequalinium bromide …
Cadmium
An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
Experimental
Matched Synonyms: … Cadmium metal ... Cadmium metallicum ... Colloidal cadmium …
Matched Name: … Cadmium …
Matched Iupac: … cadmium …
Matched Description: … It is a metal and ingestion will lead to CADMIUM POISONING. …
Matched Name: … Cadmium …
Matched Iupac: … cadmium …
Matched Description: … It is a metal and ingestion will lead to CADMIUM POISONING. …
Azoximer bromide
Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Synonyms: … Azoximer bromide ... Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene …
Matched Name: … Azoximer bromide …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Matched Name: … Azoximer bromide …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Fazadinium bromide
Experimental
Matched Synonyms: … Fazadinium bromide …
Matched Name: … Fazadinium bromide …
Matched Categories: … fazadinium bromide …
Matched Name: … Fazadinium bromide …
Matched Categories: … fazadinium bromide …
Ciclonium bromide
Experimental
Matched Synonyms: … Ciclonium bromide ... Cyclonium bromide …
Matched Name: … Ciclonium bromide …
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
Matched Name: … Ciclonium bromide …
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
Perflubron
Perflubron (Oxygent) is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients.
Investigational
Matched Synonyms: … Perfluorooctyl-bromide …
JBI-802
Investigational
Matched Synonyms: … N-hydroxy-4-((4-((((1R,2S)-2-phenylcyclopropyl) amino)methyl)-1H-pyrazol-1-yl)methyl)benzamide hydrogen bromide …
Hexatantalum Dodecabromide
Experimental
Matched Iupac: … tantalum(1+) undecahydrobromide pentatantalum bromide …
Bibenzonium
Experimental
Matched Salts name: … Bibenzonium bromide …
Matched Categories: … bibenzonium bromide …
Matched Categories: … bibenzonium bromide …
16-Bromoepiandrosterone
16-Bromoepiandrosterone is an injectable formulation of a compound called alpha-epi-bromide. It is a chemical relative of DHEA which was selected for development after it showed antiretroviral activity in laboratory tests.
Investigational
Matched Description: … 16-Bromoepiandrosterone is an injectable formulation of a compound called alpha-epi-bromide. …
Leuvectin
Leuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE).
Investigational
Matched Description: … of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide …
Timepidium
Experimental
Matched Salts name: … Timepidium bromide …
Matched Categories: … timepidium bromide …
Matched Categories: … timepidium bromide …
Thienylfentanyl
Thienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the Federal Analog Act scheduled drugs based on structural similarity rather than scheduling drugs individually. Thienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide.
Illicit
Matched Description: … similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide …
Otilonium
Experimental
Investigational
Matched Salts name: … Otilonium bromide …
Matched Categories: … otilonium bromide ... otilonium bromide and psycholeptics …
Matched Categories: … otilonium bromide ... otilonium bromide and psycholeptics …
Prifinium
Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome .
Experimental
Matched Salts name: … Prifinium bromide …
Matched Categories: … prifinium bromide …
Matched Categories: … prifinium bromide …
Displaying drugs 76 - 100 of 329 in total